• Title/Summary/Keyword: Maximum oxygen saturation

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Methemoglobinemia caused by a low dose of prilocaine during general anesthesia

  • Shibuya, Makiko;Hojo, Takayuki;Hase, Yuri;Kimura, Yukifumi;Fujisawa, Toshiaki
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.21 no.4
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    • pp.357-361
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    • 2021
  • Methemoglobinemia is a blood disorder in which an abnormal amount of methemoglobin is produced, and prilocaine is one of the drugs that can cause this disorder. The maximum recommended dose of prilocaine is 8 mg/kg. We report a case of methemoglobinemia caused by the administration of 4.2 mg/kg of prilocaine without other methemoglobinemia-inducing drugs during general anesthesia. A 17-year-old girl with hyperthyroidism and anemia was scheduled to undergo maxillary sinus floor elevation and tooth extraction. The patient's peripheral oxygen saturation (SpO2) decreased from 100% at arrival to 95% after receiving prilocaine with felypressin following induction of general anesthesia. However, the fraction of inspired oxygen was 0.6. Blood gas analysis showed that the methemoglobin level was 3.8% (normal level, 1%-2%), fractional oxygen saturation was 93.9%, partial pressure of oxygen was 327 mmHg, and arterial oxygen saturation was 97.6%. After administration of 1 mg/kg of methylene blue, her SpO2 improved gradually to 99%, and the methemoglobin value decreased to 1.2%. When using prilocaine as a local anesthetic, it is important to be aware that methemoglobinemia may occur even at doses much lower than the maximum recommended dose.

Extent and persistence of dissolved oxygen enhancement using nanobubbles

  • Tekile, Andinet;Kim, Ilho;Lee, Jai-Yeop
    • Environmental Engineering Research
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    • v.21 no.4
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    • pp.427-435
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    • 2016
  • In this study, change in water-dissolved oxygen (DO) was analyzed under various synthetic water qualities and nanobubbles (NBs) application conditions, such as gas type, initial DO as well as water dissolved, suspended and organic matters contents. When oxygen, rather than air, was introduced into nitrogen-desorbed ultra-pure water, the stagnation time was significantly increased. It took ten days for DO concentration to drop back to saturation. The higher the initial DO concentration, the longer particles were observed above saturation due to particle stability improvement. The oxygen mass transfer rate of 0.0482 mg/L/min was found to reach a maximum at an electrolytic concentration of 0.75 g/L, beyond which the transfer rate decreased due to adsorption of negative ions of the electrolyte at the interface. High levels of turbidity caused by suspended solids have become a barrier to dissolution of NBs oxygen into the water solution, and thus affected the transfer performance. On the other hand, by applying NBs for just an hour, up to 7.2% degradation of glucose as representative organic matter was achieved. Thus, NBs technology would maintain a high DO extent for an extended duration, and thus can improve water quality provided that water chemistry is closely monitored during its application.

A Study on the Development of Sleep Monitoring Smart Wear based on Fiber Sensor for the Management of Sleep Apnea (수면 무호흡증 관리를 위한 섬유센서 기반의 슬립 모니터링 스마트 웨어 개발에 관한 연구)

  • Park, Jin-Hee;Kim, Joo-Yong
    • Science of Emotion and Sensibility
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    • v.22 no.1
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    • pp.89-100
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    • 2019
  • Sleep apnea, a medical condition associated with a variety of complications, is generally monitored by standard sleep polysomnography, which is expensive and uncomfortable. To overcome these limitations, this study proposes an unconstrained wearable monitoring system with stretch-fiber sensors that integrate with the wearer's clothing. The system allows patients to undergo examinations in a familiar environment while minimizing the occurrence of skin allergies caused by adhesive tools. As smart clothing for adult males with sleep apnea, long-sleeved T-shirts embedding fibrous sensors were developed, enabling real-time monitoring of the patients' breathing rate, oxygen saturation, and airflow as sleep apnea diagnostic indicators. The gauge factor was measured as 20.3 in sample 4. The maximum breathing intake, measured during three large breaths, was 2048 ml. the oxygen saturation was measured before and during breath-holding. The oxygen saturation change was 69.45%, showing a minimum measurable oxygen saturation of 70%. After washing the garment, the gauge factor reduced only to 18.0, confirming the durability of the proposed system. The wearable sleep apnea monitoring smart clothes are readily available in the home and can measure three indicators of sleep apnea: respiration rate, breathing flow and oxygen saturation.

Early Summer Dissolved Oxygen Characteristics in Restored Streams in Seoul (서울시 복원하천들의 초여름 용존 산소량 특성 분석)

  • Thoenen, Casey;Choi, Woonsup;Choi, Jinmu
    • Journal of the Korean Geographical Society
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    • v.48 no.3
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    • pp.336-347
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    • 2013
  • This paper presents an evaluation of stream restoration projects in Seoul with a focus on dissolved oxygen. Five test sites across four streams were measured for dissolved oxygen (DO) in late May to early June in 2012 and compared against a set of minimum and maximum thresholds. Only one test site, Hwarang-cheon, showed measurements below 6 mg/l DO. Towards the upper limit, the Hwarangcheon site was the only tested stream which was not at risk of DO supersaturation. The Danghyeon-cheon site had the highest probability of supersaturation, with DO saturation exceeding 130% expected 86.5% of the time. When measured every hour during daytime, DO levels showed diurnal variations, peaking in the afternoon. However, they showed inconsistent results along transects of the streams. Overall, the streams are rich in DO. To maintain the streams in good standing, nutrient loading should be addressed to prevent potential algal bloom induced hypoxic events down the line.

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Production of Bacillus thuringiensis Spore Using an Industrial Medium (산업용 배지를 이용한 Bacillus thuringiensis의 포지생산)

  • 최성호;강석권;유연우
    • KSBB Journal
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    • v.13 no.6
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    • pp.644-648
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    • 1998
  • In the production of a low cost bacterial insecticide, it is important to produce a high spore concentration using low price substrates. Experiments were carried out to investigate the effects of the addition of mineral salts and glucose, and of dissolved oxygen concentration on the cell growth and spore formation of Bacillus thuringiensis var aizawai using a cheap wheat and soybean meal in the batch culture. The maximum viable cell number was 1.2${\times}$109 CFU/mL at 12 hr culture and spore yield was 54.2% at 74 hr culture using an industrial medium containing 20 g/L wheat meal and 30 g/L soybean meal under 1.0 vvm aeration and 200 rpm agitation. The cell growth and the spore formation were not enhanced by the addition of mineral salts in industrial medium, whereas th addition of 10g/L glucose decreased the cell growth and spore formation. We could obtain a maximum viable cell number of 2.2${\times}$109 CFU/mL and spore number of 1.9${\times}$109 CFU/mL at the dissolved oxygen concentration of 60% of saturation. The spore concentration was enhanced approximately by 2 times as compared to the dissolved oxygen concentration of 50%. In the bench-scale culture, the maximum viable cell and spore number were 2.5${\times}$109 CFU/mL, and 2.2${\times}$109 CFU/mL, respectively under 1.0 vvm aeration and 400 rpm agitation. The spore yield was 88% based on the maximum viable cell number. As a result, it was confirmed that the production of high spore concentration could be obtained by a bench-scale culture using an industrial medium.

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Effect of Amino Acids and Dissolved Oxygen on Expression of Invertase in Recombinant Saccharomyces cerevisiae (재조합 Saccharomyces cerevisiae의 Invertase 발현에 미치는 아미노산과 용존산소의 영향)

  • 신해헌;조정섭;변유량;박혜영
    • Microbiology and Biotechnology Letters
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    • v.20 no.3
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    • pp.348-354
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    • 1992
  • In order to improve the productivity of invertase by recombinant Saccharomyces cerevisiae containing SUC2 gene, the effect of amino acids and dissolved oxygen concentration on the gene expression was investigated. Optimal concentrations of leucine and histidine for cell growth and cloned gene expression were 0.03 gig and 0.04 gig, respectively, expressed as the ratio of amino acid/glucose. The lack or excess of leucine and histidine has inhibitory effect on cell growth and invertase expression. In batch culture, the less aeration was, the higher invertase activity was. In continuous culture at a dilution rate of 0.09 h 1 with controlled dissolved oxygen tension, invertase activity increased dramatically at DOT levels below 5% air saturation, and a maximum activity of 215.54 KUlg cell was obtained under unaerated condition.

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Electronic Structure of the SrTiO3(001) Surfaces: Effects of the Oxygen Vacancy and Hydrogen Adsorption

  • Takeyasua, K.;Fukadaa, K.;Oguraa, S.;Matsumotob, M.;Fukutania, K.
    • Applied Science and Convergence Technology
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    • v.23 no.5
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    • pp.201-210
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    • 2014
  • The influence of electron irradiation and hydrogen adsorption on the electronic structure of the $SrTiO_3$ (001) surface was investigated by ultraviolet photoemission spectroscopy (UPS). Upon electron irradiation of the surface, UPS revealed an electronic state within the band gap (in-gap state: IGS) with the surface kept at $1{\times}1$. This is considered to originate from oxygen vacancies at the topmost surface formed by electron-stimulated desorption of oxygen. Electron irradiation also caused a downward shift of the valence band maximum indicating downward band-bending and formation of a conductive layer on the surface. With oxygen dosage on the electron-irradiated surface, on the other hand, the IGS intensity was decreased along with upward band-bending, which points to disappearance of the conductive layer. The results indicate that electron irradiation and oxygen dosage allow us to control the surface electronic structure between semiconducting (nearly-vacancy free: NVF) and metallic (oxygen de cient: OD) regimes by changing the density of the oxygen vacancy. When the NVF surface was exposed to atomic hydrogen, in-gap states were induced along with downward band bending. The hydrogen saturation coverage was evaluated to be $3.1{\pm}0.8{\times}10^{14}cm^{-2}$ with nuclear reaction analysis. From the IGS intensity and H coverage, we argue that H is positively charged as $H^{{\sim}0:3+}$ on the NVF surface. On the OD surface, on the other hand, the IGS intensity due to oxygen vacancies was found to decrease to half the initial value with molecular hydrogen dosage. H is expected to be negatively charged as $H^-$ on the OD surface by occupying the oxygen vacancy site.

Observation of Bottom Water Renewal and Export Production in the Japan Basin, East Sea Using Tritium and Helium Isotopes

  • Hahm, Do-Shik;Kim, Kyung-Ryul
    • Ocean Science Journal
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    • v.43 no.1
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    • pp.39-48
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    • 2008
  • Tritium ($^3H$ or T) has been produced mostly by atmospheric nuclear weapon tests, and entered the ocean in the form of water (HTO). As tritium exists as water itself, it has been regarded as an ideal tool to study the transport of water masses. In April 2001 we collected water samples in the western Japan Basin (WJB) for tritium and helium measurement. The timely sampling provided direct evidence of the bottom water formation, resulting in the drastic increase in tritium concentration from 0.3 TU in 2000 to 0.67 TU in 2001. Considering that the new bottom waters were found mostly in the WJB, it implies that maximum 1% of the whole bottom layer below 2600 m should be replaced with the surface water during the severely cold winter 2000 2001. $^3H-^3He$ age, showing the elapsed time since the water left from the surface, can be used to calculate oxygen utilization rate by dividing AOU by the age. Under the condition of 90% oxygen saturation in the surface water, the integration of OUR in the water column below 200 m yields net oxygen consumption of 12 mol $(O_2)m^{-2}yr^{-1}$, which corresponds to the export production of $99\;g\;C\;m^{-2}yr^{-1}$. This estimate is comparable to a previous estimate based on satellite data and implies that the ratio of export to primary production(f-ratio) is as high as 0.5 in the WJB.

Characterization of oxygen plasma by using a langmuir probe in the inductively coupled plasma (정전 탐침을 이용한 유도 결합형 반응기에서 발생하는 산소 플라즈마의 특성연구)

  • 김종식;김곤호;정태훈;염근영;권광호
    • Journal of the Korean Vacuum Society
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    • v.9 no.4
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    • pp.428-435
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    • 2000
  • Negative ion generation in an inductively coupled oxygen plasma was investigated by using a Langmuir probe. It was observed that the probe current ratio of the positive ion saturation current and the negative current which is consisted of the electron current and the negative ion current, and also the potential difference between the floating potential and plasma potential vary with the RF input power and more sensitively with the operating pressure, respectively. Results show that the operating condition to achieve the maximum probe current ratio and the minimum potential difference shift from the low pressure region to the high pressure regions with increasing the input power. It implies that the generation of the negative oxygen ions increases and the recombination of the positive and negative ions are enhanced in the plasma.

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Kinetic Analysis for Paper-mill Wastewater Treatment Using Pure Oxygen Activated Sludge Process (순산소 활성오니공정을 이용한 제지폐수처리의 동력학적 해석)

  • Kim, Sung Soon;Chung, Tai Hak
    • Journal of Korean Society of Water and Wastewater
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    • v.14 no.2
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    • pp.157-163
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    • 2000
  • An experimental study was conducted to evaluate the treatment efficiency of paper-mill wastewater using pure oxygen activated sludge process. Effects of hydraulic retention time (HRT) and organic loading on process performance and kinetics were investigated. The raw paper-mill wastewater(BOD concentration ${\leq}500mg/L$) and the effluent from dissolved air flotation(DAF) treatment(BOD concentration ${\geq}500mg/L$) were used as influent for pure oxygen activated sludge process. Average BOD removal efficiencies were above 89.3% under 6hours or longer of HRT, while under 3hours of HRT they decreased to about 82%. With the effluent from DAF process, the half saturation constants($K_S$) and the maximum specific substrate removal rate($K_{max}$) were 85 mg/L and 2.25 L/day, respectively. However, with the raw paper-mill wastewater, both $K_S$ and $K_{max}$ increased to 156 mg/L and 3.84 L/day, respectively. The microbial yield coefficient(Y) and the decay coefficient($K_d$) were 0.46 gVSS/gBOD and 0.03 L/day, respectively, with effluent from DAF process. While, Y and $K_d$ were 0.24 gVSS/gBOD and 0.035 L/day, respectively, with the raw paper-mill wastewater.

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