• 제목/요약/키워드: Mature

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지방세포 3T3-L1에 인삼 사포닌 Re와 의이인 추출액 처리시 비만관련 유전자인 TNF-α, lipoprotein lipase, leptin 및 resistin 발현 조절에 미치는 영향 (Ginseng Saponin-Re and Coix lachrymajobi var. mayuen Regulate Obesity Related Genes Expressions, TNF-alpha, Leptin, Lipoprotein Lipase and Resistin in 3T3-L1 Adipocytes)

  • 김성옥
    • 생명과학회지
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    • 제17권11호
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    • pp.1523-1532
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    • 2007
  • 전통적인 한방약물로 이용되는 인삼(사포닌 Re)과 의이인 추출물을 분화단계별 지방세포에 $100\;{\mu}g/ml$ 씩 12일간 이틀에 한번씩 각각의 물질을 처리하였다. 비만지표 유전자로 알려져 있는 여러 유전자의 발현양을 mRNA와 단백질 수준에서 조사하였다. 완전성숙 지방세포에서 약물의 처리에 따라 $TNF-{\alpha}$ 발현이 비처리 세포에 비해 현저히 억제되었고, lipoprotein lipase는 mRNA와 단백질수준에서 그 발현 양이 증가하였다. 약물처리 세포에서 leptin과 resistin의 유전자 발현은 비처리세포에 비해 유의적인 감소되었다. 이러한 결과는 인삼 사포닌 뿐 아니라 의이인 추출액에서도 유사한 영향이 관찰되어 특히, 곡물인 의이인 추출액이 인삼 사포닌과 거의 비슷한 항비만 활성을 나타내어 장복으로 인한 세포독성을 최소화하면서 지방세포에 긍정적 영향을 미칠 뿐 아니라 인슐린 저항성 개선 효과도 기대되어진다. 향후 대사성 질환과 밀접한 관련이 있는 비만 관리 향상에 이용 할 수 있을 것으로 사료되어진다. 따라서 이 결과들을 바탕으로 동물실험을 통한 더 자세한 조절기능의 확인과 특히, 의이인 추출액에서의 생리활성물질에 대해서도 많은 체계적인 분석과 관련연구가 필요 할 것으로 사료된다.

모유의 셀레늄과 아연 함량에 관한 연구 (A Study on the Contents of Selenium and Zine in Human Milk)

  • 양혜란
    • Journal of Nutrition and Health
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    • 제28권9호
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    • pp.872-879
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    • 1995
  • The changes of selenium and zine contents of transitional milk and mature milk at 7 and 60 days postpartum were comparatively studied on 20 Korean lactating women. the selenium and zinc contents of transitional milk and mature milk were analyzed by atomic absorption spectrophotometer after wet-digestion. The mean selenium contents wer 12.2$\mu\textrm{g}$ /ι and 11.5$\mu\textrm{g}$/ι at 7 and 60 days postpartum, respectively. The mean zinc contents decreased significantly from 4.23mg/ι at 7 days to 1.62mg/ι at 60 days postpartum (p<0.05).

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가입자망 진화방향 (Evolution of optical access networks)

  • 김보겸;고석봉;이원형;한진우
    • 한국정보통신설비학회:학술대회논문집
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    • 한국정보통신설비학회 2009년도 정보통신설비 학술대회
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    • pp.187-189
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    • 2009
  • Fibre to the home (FTTH) in KOREA has grown rapidly in recent years. The number of FTTH subscribers exceeded 6.6 millions by end of DEC 2008. It seems that FTTH has moved from the initial, the growth stage to the mature stage. Some design techniques have been developed in order to construct the access network effectively for the mature stage. This paper deal with design, construction and maintenance of optical fibre access networks immediately, effectively and economically.

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Stability and Optimal Harvesting in Lotka-Volterra Competition Model for Two-species with Stage Structure

  • Al-Omari, J.F.M.
    • Kyungpook Mathematical Journal
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    • 제47권1호
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    • pp.31-56
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    • 2007
  • In this paper, we consider a delay differential equation model of two competing species with harvesting of the mature and immature members of each species. The time delay in the model represents the time from birth to maturity of that species, which appears in the adults recruitment terms. We study the dynamics of our model analytically and we present results on positivity and boundedness of the solution, conditions for the existence and globally asymptotically stable of equilibria, a threshold of harvesting, and the optimal harvesting of the mature populations of each species.

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생장조절제 및 경경도가 성숙Aloe 발근에 미치는 영향 (The effect of growth substance and stem hardness on rooting of mature aloe plant)

  • 심재성
    • 한국자원식물학회지
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    • 제8권3호
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    • pp.217-222
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    • 1995
  • Experiments were conducted to study the effect of IBA, mineral stone and stem hardness on rooting characteristics in mature Aloe vera plant. The rooting ability in matured Aloe vera was of highly significance when the amount of IBA treatment was increased to 5.000mg/l. The treatment of IBA 5.000mg/l, together with mineral stone(v/w 1.5 times), gave more root number, the length and the dry weight of root were, also, higher in semihard wood cutting than soft wood cutting in matured Aloe vera.

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Stability and Folding of a Mutant Ribose Binding Protein of Escherichia coli

  • Kim, Joon-Sik;Kim, Hyoungman
    • 한국생물물리학회:학술대회논문집
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    • 한국생물물리학회 1996년도 정기총회 및 학술발표회
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    • pp.25-25
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    • 1996
  • A mature mutant ribose binding protein (RBP) of Escherichia coli was obtained by site-directed mutagenesis, replacing Thr-3 in the N-domain of wild-type mature RBP (WT -mRBP) with a Trp residue (N- Trp-mRBP). The equilibrium unfolding properties and the refolding kinetics of this protein were monitored by fluorescence and circular dichroism (CD). (omitted)

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구개 편도 지방종 1례 (A Case of Lipoma of Palatine Tonsil)

  • 최홍식;신승호;김한수;서용석
    • 대한기관식도과학회지
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    • 제7권1호
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    • pp.59-61
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    • 2001
  • Lipomas is one of the most common benign neoplasm in the body, but only rarely occurs in the oral cavity We report here a case of a 49-year-old female with a lipoma of palatine tonsil. Microscopical examination revealed a stromal neoplasm composed of mature fat with the presence of a few thin and anastomosing fibrous septa. The surface epithelium was of nonkeratinizing stratified squamous type. There was the dense fibrous connective tissue between mature fat and surface epithelium. The histopathologic findings and literature on tonsillar lipoma is reviewed.

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황색종 잎담배 (N. tabacum L.)의 유기산과 숙도에 관한 연구 (Studies on the Relationship of Maturity and Organic Acids Composition in the Flue-cured Tobacco Leaves.)

  • 이문수;김찬호
    • 한국연초학회지
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    • 제6권1호
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    • pp.73-78
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    • 1984
  • The changes of contents of organic acids in flue-cured tobacco leaves depending on stalk position and maturity viz immature, mature and overmature were studied in 1982-83. Among them, particularly, the leaves harvested at mature stage have the lowest amounts of oxalic and citric acids in smoking or cutter leaves but the acid contents has increased during the overmature. The linolenic acid content tended to be lower with increase of maturity.

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Interaction of Beef Growth Type${\times}$Production System for Carcass Traits of Steers

  • Brown , A.H. Jr.;Camfield, P.K.;Johnson, Z.B.;Rakes, L.Y.;Pohlman, F.W.;Brown, C.J.;Sandelin, B.A.;Baublits, R.T.
    • Asian-Australasian Journal of Animal Sciences
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    • 제18권2호
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    • pp.259-266
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    • 2005
  • Steers (n=335) of known genetic backgrounds from four fundamentally different growth types were subjected to two production systems to study differences in carcass traits. Growth types were animals with genetic potential for large mature weight-late maturing, intermediate mature weight-late maturing, intermediate mature weight-early maturing and small mature weight-early maturing. Each year, in a nine-year study, calves of each growth type were weaned and five steers of each growth type were developed on pasture or feedlot and slaughtered at approximately 20 and 14 months of age, respectively. Data collected were pre-slaughter shrunk body weight (SBW); hot carcass weight (HCW); dressing percentage (DRESS); fat thickness at the $12^{th}$ and $13^{th}$ rib interface (FAT); percentage kidney, pelvic, and heart fat (KPH); longissimus muscle area (LMA); marbling score (MARB); quality grade (QG); and yield grade (YG). Year and growth type were significant for all carcass traits. The growth type${\times}$production system interaction was an important source of variation in SBW, HCW; FAT, YG and MARB. The same interaction was non-significant for DRESS, KPH, LMA and QG. Carcass differences in measures of fatness were greater in the feedlot system than in the pasture system. These data could aid producers in matching beef growth type to the production system most suitable for efficient use of resources.

Improvement of the Vitrification Method Suppressing the Disturbance of Meiotic Spindle and Chromosome Systems in Mature Oocytes

  • Jung, Yun Jin;Cheon, Yong-Pil
    • 한국발생생물학회지:발생과생식
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    • 제18권2호
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    • pp.117-125
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    • 2014
  • Vitrification method is widely used in oocyte cryopreservation for IVF but the birth rates are lower than that of the fresh oocyte. One of the known main reasons is structural instability of meiotic spindle and chromosome systems of mature oocyte. To get the best way for keeping competence of matured oocytes, we studied the best conditions for vitrification focused on equilibration times. The mature oocytes were underwent vitrification with current popular method and analyzed the survival rates, microtubule stability and DNA integrity. The survival rates of recovered oocyte are almost same between groups and are more than 93%. The structural configuration of meiotic spindle was well kept in 10 min equilibration group and the stability rate was almost same with that of control. The chromosomal breakdown was observed in all experimental groups, but the chromosomal stability was higher in 10 min equilibration group than the other groups. The 10 min equilibration group showed best condition compared with the other groups. Based on these results, the equilibration time is one of the key factors in successful keeping for competence of mature oocyte. Although, more fine analysis about the effects of physical stress on oocyte during vitrification is needed to define the optimal condition, it is suggested that the optimal equilibration time to get competent oocyte in mouse is 10 min. Information acquired this study may provide insight into intracellular structural events occurring in human oocytes after vitrification and application for cryopreservation of human oocyte.