• Title/Summary/Keyword: Matrix structure

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STUDY ON EXPRESSION OF GLYCOSAMINOGLYCAN IN ADENOID CYSTIC CARCINOMA (선양낭성암종(Adenoid Cystic Carcinoma)에서의 Glycosaminoglycan의 발현에 관한 연구)

  • Son, Chang-Won;Kim, Kyung-Wook;Kim, Chul-Hwan
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.30 no.4
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    • pp.271-281
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    • 2004
  • Adenoid cystic carcinoma is malignant tumor in salivary gland, and its behavior is very invasive. Of all malignant tumor adenoid cystic carcinoma is occured in frequency of 4.4% in major salivary gland, and 1.29% in minor salivary gland. Histopathologically, adenoid cystic carcinoma is characterized by a cribriform appearance, and tubular form and solid nest type tumor can be seen. The tumor cell structure composed of modified myoepithelial cell, and basaloid cell. Extracellular matrix of this tumor cell contains variable ground substance with basement membrane component. Basement membrane matrix composed of collagen fibers, glycoproteins, proteoglycans, and its function is well known that it participate in differentiation, proliferation, and growth of tumor cell. Basement membrane molecule is essential for invasion of peripheral nerve, blood vessel, skeletal muscle in tumor cell of adenoid cystic carcinoma. In many studies, the tumor cell of adenoid cystic carcinoma containing modified myoepithelial cell participate in synthesis of proteoglycan. In this study, tissue sample of adenoid cystic carcinoma of human salivary gland were obtained from 15 surgical specimen, and all specimen were routinely fixed in 10% formalin and embedded. Serial $4-{\mu}m$ thick sections were cut from paraffin blocks. the histopathologic evaluation was done with light microscopy. And, the immunohistochemical staining, characteristics of glycosaminoglycan were observed. For biochemical analysis of glycosaminoglycan, isolation of crude glycosaminoglycan from tumor tissue and Western bolt analysis were carried out. With transmission electomicroscopy, tumor cell were observed. Biologic behavior of adenoid cystic carcinoma was observed with distribution and expression of basement membrane of glycosaminoglycan in tumor cells, The results obtained were as follows: 1. In immunohistochemical study, chondroitin sulfate is postively stained in tumor cell and interstitial space, dermatan sulfate is weakly stained in ductal cell. But keratan sulfate is negatively stained. 2. In immunohistochemical study, heparan sulfate is strong positive stained in tumor cell and basement membrane, especially in invasion area to peripheral nerve tissue. 3. In transmission electromicroscpic view, the tumor cells are composed modifed myoepithelial cells, and contains many microvilli and rough endoplasmic reticulum. 4. In Western blot analysis, the expression of glycosaminoglycan is expressed mostly in heparan sulfate. From the results obtained in this study, tumor cell of adenoid cystic carcinoma is composed modified myoepithelial cell, and glycosaminoglycan of basement membrane molecule of heparan sulfate and chondroitin sulfate mostly participate in the development and invasiveness of adenoid cystic carcinoma by immunohistochemical study and western blot analysis.

Stereo Vision Based 3D Input Device (스테레오 비전을 기반으로 한 3차원 입력 장치)

  • Yoon, Sang-Min;Kim, Ig-Jae;Ahn, Sang-Chul;Ko, Han-Seok;Kim, Hyoung-Gon
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.39 no.4
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    • pp.429-441
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    • 2002
  • This paper concerns extracting 3D motion information from a 3D input device in real time focused to enabling effective human-computer interaction. In particular, we develop a novel algorithm for extracting 6 degrees-of-freedom motion information from a 3D input device by employing an epipolar geometry of stereo camera, color, motion, and structure information, free from requiring the aid of camera calibration object. To extract 3D motion, we first determine the epipolar geometry of stereo camera by computing the perspective projection matrix and perspective distortion matrix. We then incorporate the proposed Motion Adaptive Weighted Unmatched Pixel Count algorithm performing color transformation, unmatched pixel counting, discrete Kalman filtering, and principal component analysis. The extracted 3D motion information can be applied to controlling virtual objects or aiding the navigation device that controls the viewpoint of a user in virtual reality setting. Since the stereo vision-based 3D input device is wireless, it provides users with a means for more natural and efficient interface, thus effectively realizing a feeling of immersion.

Photocurrent study on the splitting of the valence band and growth of $Cdln_2Te_4$ single crystal by Bridgman method (Bridgman법에 의한 $Cdln_2Te_4$단결정의 성장과 가전자대 갈라짐에 대한 광전류 연구)

  • 홍광준;이관교;이봉주;박진성;신동찬
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.13 no.3
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    • pp.132-138
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    • 2003
  • A stoichiometric mixture for $CdIn_2Te_4$ single crystal was prepared from horizontal electric furnace. The $CdIn_2Te_4$ single crystal was grown in the three-stage vertical electric furnace by using Bridgman method. The $CdIn_2Te_4$ single crystal was evaluated to be tetragonal by the power method. The (001) growth plane of oriented $CdIn_2Te_4$ single crystal was confirmed from back-reflection Laue patterns. The carrier density and mobility of $CdIn_2Te_4$ single crystal measured with Hall effect by van der Pauw method are $8.61\times 1016 \textrm {cm}^{-3}$ and 242 $\textrm{cm}^2$/V.s at 293 K, respectively. The temperature dependence of the energy band gap of the $CdIn_2Te_4$ single crystal obtained from the absorption spectra was well described by the Varshni's relation, $1.4750ev - (7.69\times10^{-3})\; ev/k)\;T^2$/(T + 2147k).The crystal field and the spin-orbit splitting energies for the valence band of the $CdIn_2Te_4$ single crystal have been estimated to be 0.2704 eV and 0.1465 eV, respectively, by means of the photocurrent spectra and the Hopfield quasicubic model. These results indicate that the splitting of the $\Delta$so definitely exists in the $\Gamma_7$ states of the valence band of the $CdIn_2Te_4$ single crystal. The three photocurrent peaks observed at 10 K are ascribed to the $A_{1-} B_{1-}$ and Cl-exciton peaks for n = 1.

Durability of Polymer-Modified Mortars Using Acrylic Latexes with Methyl Methacrylate (MMA계 아크릴 라텍스를 혼입한 폴리머시멘트 모르타르의 내구성)

  • Hyung Won-Gil;Kim Wan-Ki;Soh Yang-Seob
    • Journal of the Korea Concrete Institute
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    • v.17 no.3 s.87
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    • pp.411-418
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    • 2005
  • Polymer-modified mortar and concrete are prepared by mixing either a polymer or monomer in a dispersed, or liquid form with fresh cement mortar and concrete mixtures, and subsequently curing, and if necessary, the monomer contained in the mortar or concrete is polymerized in situ. Although polymers and monomers in any form such as latexes, water-soluble polymers, liquid resins, and monomers are used in cement composites such as mortar and concrete, it is very important that both cement hydration and polymer phase formation proceed well the yield a monolithic matrix phase with a network structure in which the hydrated cement phase and polymer phase interpenetrate. In the polymer-modified mortar and concrete structures, aggregates are bound by such a co-matrix phase, resulting in the superior properties of polymer-modified mortar and concrete compared to conventional mortar and concrete. The purpose of this study is to obtain the necessary basic data to develope appropriate latexes as cement modifiers, and to clarify the effects of the monomer ratios and amount of emulsifier on the properties of the polymer-modified mortars using methyl methacrylate-butyl acrylate(MMA/BA) and methyl methacrylate-ethyl acrylate(MMA/EA) latexes. The results of this study are as follows, the water absorption, chloride ion penetration depth and carbonation depth of MMA/BA-modified mortar are lowest. However, they are greatly affected by the polymer-cement ratio rather than the bound MMA content and type of polymer.

A Design of the New Three-Line Balun (새로운 3-라인 발룬 설계)

  • 이병화;박동석;박상수
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.14 no.7
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    • pp.750-755
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    • 2003
  • This paper proposes a new three-line balun. The equivalent circuit of the proposed three-line balun is presented, and impedance matrix[Z]of the equivalent circuit is derived from the relationship between the current and voltage at each port. The design equation for a given set of balun impedance at input and output ports is presented using[S]parameters, which is transferred fom impedance matrix,[Z]. To demonstrate the feasibility and validity of design equation, multi-layer ceramic(MLC) chip balun operated in the 2.4 GHz ISM band frequency is designed and fabricated by the use of the low temperature co-fired ceramic(LTCC) technology. By employing both the proposed new three-line balun equivalent circuit and multi-layer configuration provided by LTCC technology, the 2012 size MLC balun is realized. Measured results of the multi-layer LTCC three-line balun match well with the full-wave electromagnetic simulation results, and measured in band-phase and amplitude balances over a wide bandwidth are excellent. This proposed balun is very easily applicable to multi-layer structure using LTCC as shown in the paper, and also can be realized with microstrip lines on PCB. This distinctive performance is very favorable for wireless communication systems such as wireless LAN(Local Area Network) and Bluetooth applications.

Quality and Storage Characteristics of Mechanically Deboned Chicken Meat Added Chicken Sausage (기계발골 계육이 첨가된 계육 소시지의 품질 및 저장특성)

  • Lee, Jae-Joon;Choi, Jung-Soek;Jung, Dong-Soon;Park, Sung-Hyun;Choi, Yang-Il
    • Food Science of Animal Resources
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    • v.31 no.3
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    • pp.460-468
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    • 2011
  • We evaluated the effect of adding mechanically deboned chicken meat (MDCM) (0, 10, 20, 30 or 50%) on quality characteristics of chicken sausage. Adding MDCM decreased the protein content of chicken sausage, but ash content increased significantly. Adding MDCM had no effect on pH and water holding capacity of sausage. Adding MDCM increased cooking loss, but did not affect the shear force value of the sausage. Adding MDCM decreased the L- (lightness) and b- (yellowness) values but increased the a- (redness) value of sausage. Adding MDCM decreased the hardness and cohesiveness values, but did not affect the springiness value of chicken sausage. Adding MDCM decreased the juiciness and hardness but increased the flavor and chewiness scores of chicken sausage. Regardless of the MDCM addition level, all chicken sausage contained low residual nitrite ion (<4 ppm). During the 10 d of storage at $4^{\circ}C$, adding MDCM did not affect total microbial count or TBA values of chicken sausage, but the VBN value of the sausage increased slightly. However, all storage characteristic values in the sausage were within the safety range. Adding MDCM (0, 10 or 20%) to chicken sausage resulted in a finely structured protein matrix under scanning electron microscopy (SEM), which indicated a good meat emulsion, but adding MDCM at more than 20% resulted in a very coarse protein matrix structure.

Influence of Activation Temperature on Surface and Adsorption Properties of PAN-based Activated Carbon Fibers/Phenolic Resin Matrix Composites (활성화 온도에 의한 PAN계 활성탄소섬유/페놀수지 복합재료의 표면 및 흡착특성)

  • 박수진;김기동;이재락
    • Polymer(Korea)
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    • v.24 no.1
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    • pp.97-104
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    • 2000
  • PAN-based activated carbon fibers/phenolic resin matrix composites (ACFCs) were manufactured via molding process with oxidized carbon fabrics (plain-type) and phenolic resin (resole-type) compounded by 70 : 30 wt%. The green body (as molded) was submitted to carbonization (at 100$0^{\circ}C$) in an inert environment and activation (at 700, 800, 900 and 100$0^{\circ}C$) in a $CO_2$ environment. In this work, the influence of activation temperatures was investigated in surface properties, such as pH, acid- and base-values by titration method, and in adsorption properties, i.e., specific surface area and pore structures by BET-method of the composites. Also, the pressure drops of the specimens were calibrated by ASTM. As a result, the activation temperature influenced the surface property of ACFCs. When the activation temperature was higher than 90$0^{\circ}C$, the surface was gradually developed in basic nature. And, the evolutions of specific surface area, total pore volume and pore size distribution of ACFCs could be easily confirmed the dependence on the activation temperature. Among them, well-developed pore structure from adsorption characteristics was changed of the ACFCs activated at 90$0^{\circ}C$. Also, the pressure drop was slightly decreased with increasing the temperature due to increasing the burn-off with heat treatment temperature of ACFCs.

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Morphological Interpretation of the Transformation Process of Urban Form in Gosan-Up (형태학적 개념을 활용한 조선시대 고산현의 도시형태 변천과정 해석)

  • Lee, Kyung-Chan;Kang, In-Ae
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.32 no.4
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    • pp.37-49
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    • 2014
  • This paper aims to interpret the transformation process of town plan of Gosan-up(高山), which was provincial administrative focus town in Josun dynasty, basing on morphological viewpoint. Morphological concepts, such as morphological frame, urban plan, kernel, colonization, route system, fixation line, fringe belt, plan unit & plan division, morphological period derived from the study of Conzen, M.R.G. and Caniggia, G. epidome district, break point, broken plot, urban fallow, privatization are adopted for the interpretation of urban form. Morphological period of Gosan can be divided in four ; formation of kernel & morphological structure, disintegration & redevelopment of the kernel, augmentative development of the kernel & formation of modern epidome district, outwards expanding of urbanized area, transition & reorganization of epidome district. Especially public leading projects such as construction of new regional connection road and public facilities such as myeon(township) office, agricultural cooperatives federation office, market, are main factors of morphological transformation of townplan. In the early stage, under the Japanese imperialism, construction of the new matrix route(Gosan-ro) through the kernel and followed planned routes gave way to disintegrating traditional areal plan unit and forming small block plan units in administrative facilities area. And linear plan units with commercial buildings were formed along the new matrix route and planned route adjacent to periodical market. In the latter stage, with development of public facilities, private sectors' large circulation institution and terminal outside the kernel with planned routes formed areal block based plan units with commercial and public buildings. And part of the spatial area with the linear plan unit were turned into urban fallow. With the transformation of town plan, new roads outside the kernel have substituted for traditional fixation line of waterway with road and topographical feature. Fringe belts were made successively along the new road and around the major intersections outside of existing urbanized area. Land use in fringe belts, constituting of outer locational tendency early on formation, was gradually replaced with commercial & business buildings.

The Structure of Korean Consonants as Perceived by the Japanese (일본인이 지각하는 한국어 자음의 구조)

  • Bae, Moon-Jung;Kim, Jung-Oh
    • Korean Journal of Cognitive Science
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    • v.19 no.2
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    • pp.163-175
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    • 2008
  • Twelve Japanese students living in South Korea have been examined for their perceptual identification of an initial consonant in Korean syllables with or without a white noise. A confusion matrix was then subject to analyses of additive clustering, individual difference scaling, and probability of information transmission, the results of which were also compared to those of South Koreans. The Japanese in the present experiment confused /다/and/타/ most frequently, followed by /가/ and /카/, /자, 차, 짜/, /타/ and /따/, and so on. The results of additive clustering analysis of the Japanese significantly differed from those of the South Koreans. Individual difference scaling revealed dimensions of sonorant, aspiration and coronal. While South Koreans showed binary values on aspiration and tenseness dimensions, the Japanese did continuous values on such dimensions. An information transmission probability analysis revealed that the Japanese participants could not perceive very well such larynx features as tenseness and aspiration compared to the South Korean participants. The former group, however, perceived very well place of articulation features such as labial and coronal. The present results suggest that an approach dealing with structures of base representations is important in understanding the phonological categories of languages.

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Biochemical and Histological Effects of Phellinus linteus Methanol Extract on Liver Lipid Metabolism of Rats Fed $CCl_4$ and High Fat (상황버섯이 사염화탄소와 고지방을 투여한 흰쥐의 간지질 대사에 미치는 생화학적, 형태학적 연구)

  • 정차권;정명은;함승시;남상명;강일준;김수진
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.30 no.2
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    • pp.331-337
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    • 2001
  • The effect of Phellinus linteus methanol extract on the lipid metabolism in the liver of rat was investigated in this study. Rats were randomly divided into 6 groups including the control, $CCl_4$and high fat group plus sub-groups with Phellinus linteus methanol extract administration. Methanol extracts of Phellinus linteus were fed 50mg/kg B.W daily via drinking water. A 1.2mL of $CCl_4/kg$ body weight was administered by oral intubation twice a week for total six times. The administration of $CCl_4$ increased total cholesterol, TG, LDL and LDL-phospholipid. However, the level of liver cholesterol and triglycerides were significantly decreased while HDL-cholesterol was increased by the extract feeding. The activities of GOT, GPT, AP and LDH were greatly enhanced by the extract feeding. Electronmicrograph showed that $CCl_4$ treatment deteriorated the structure of cytoplasmic matrix with its uneven distribution. However, the extract treatment reconstituted the damaged cytoplasm and stimulated mitochondriagenesis. From these results, it was suggested that Phellinus linteus can help to recover the damaged liver function and further may help to prevent senescence diseases such as fatty liver, hypertension and hyperlipidemia.

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