• Physical Therapy Korea
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• v.14 no.4
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• pp.21-27
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• 2007

The purposes of this study were to compare core muscle activities with and without the use of Pilates resistive equipment during bridging exercises and to investigate the efficacy of a Pilates device. Fourteen healthy individuals (6 males, 8 females) between 20 to 26 years of age were examined. They were engaged in a bridging exercise with and without a magic circle. Three consecutive repetitions of each exercise were performed. Surface electromyography (sEMG) was used to measure the electrical activities of the right side internal oblique, the adductor longus, the multifidus, and the gluteus maximus muscles. Normalized EMG activities were compared using a paired t-test and the level of significance was set at =.05. The results showed that the EMG activities of the internal oblique (p=.0078), the adductor longus (p=.0007), and the gluteus maximus (p=.0001) muscles were significantly higher when using the magic circle during the Pilates bridging exercise. Also, statistically significant change existed in the multifidus muscle (p=.0106). The bridging exercise, combined with hip adduction using the magic circle, may enhance core stabilization. Therefore, using a magic circle during hip adduction combined with bridging exercise may be recommended usefully for individuals wanting to strength the core muscles. Further research is needed to access the nature of motor control of the Pilates mat exercises and to deliver exercise intervention for lower back pain patients.

• Molecules and Cells
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• v.27 no.3
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• pp.365-381
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• 2009

The chloroplast DNA sequences of Megaleranthis saniculifolia, an endemic and monotypic endangered plant species, were completed in this study (GenBank FJ597983). The genome is 159,924 bp in length. It harbors a pair of IR regions consisting of 26,608 bp each. The lengths of the LSC and SSC regions are 88,326 bp and 18,382 bp, respectively. The structural organizations, gene and intron contents, gene orders, AT contents, codon usages, and transcription units of the Megaleranthis chloroplast genome are similar to those of typical land plant cp DNAs. However, the detailed features of Megaleranthis chloroplast genomes are substantially different from that of Ranunculus, which belongs to the same family, the Ranunculaceae. First, the Megaleranthis cp DNA was 4,797 bp longer than that of Ranunculus due to an expanded IR region into the SSC region and duplicated sequence elements in several spacer regions of the Megaleranthis cp genome. Second, the chloroplast genomes of Megaleranthis and Ranunculus evidence 5.6% sequence divergence in the coding regions, 8.9% sequence divergence in the intron regions, and 18.7% sequence divergence in the intergenic spacer regions, respectively. In both the coding and noncoding regions, average nucleotide substitution rates differed markedly, depending on the genome position. Our data strongly implicate the positional effects of the evolutionary modes of chloroplast genes. The genes evidencing higher levels of base substitutions also have higher incidences of indel mutations and low Ka/Ks ratios. A total of 54 simple sequence repeat loci were identified from the Megaleranthis cp genome. The existence of rich cp SSR loci in the Megaleranthis cp genome provides a rare opportunity to study the population genetic structures of this endangered species. Our phylogenetic trees based on the two independent markers, the nuclear ITS and chloroplast MatK sequences, strongly support the inclusion of the Megaleranthis to the Trollius. Therefore, our molecular trees support Ohwi's original treatment of Megaleranthis saniculifolia to Trollius chosenensis Ohwi.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.34 no.8
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• pp.1083-1089
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• 2010

Shape memory alloys (SMAs) are smart materials. The unique characteristics of SMAs enable the production of large force and displacement. Hence, SMAs can be used in many applications such as in actuators and active structural acoustic controllers; the SMAs can also be used for dynamic tuning and shape control. A SMA torque tube actuator consisting of SMA tubes and superelastic springs is proposed, and the behaviors of the actuator are investigated. From the results of heat transfer analysis, it is proved that the SMA torque tube actuator with both resistive heating of SMA itself and a separate conventional heating rod in the tube core has good performance. The behavior of an actuator system was analyzed by performing a contact analysis, and the twisting motion was noticed when checking the actuation. 3D SMA nonlinear constitutive equations were formulated numerically and implemented by performing a nonlinear analysis by using Abaqus UMAT.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.10 no.1
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• pp.37-45
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• 1990

An analytical procedure is proposed for the seismic analysis of a soil-structure interaction system with besemat uplift, including the effects of concurrent vertical seismic ground motion, nonlinear distribution of bearing soil pressure under the basemat, and 3-dimensional behavior of the system. The soil-structure interaction system is assumed to have rectangular-shaped basemat on elastic half-space. Nonlinearity of soil spring constants and soil damping coefficients induced by the base mat uplift is modeled by considering not only the reduction of contact area between soil and structure but also the effects of rigid body rotational motion of the superstructure, and the shift in the point of action of the resultant reaction on the basemat. Throught various parametric studies. it has been confirmed that the seismic responses of the superstructure reduce notably while response at the basemat increases considerably. The results also show that the effects of concurrent vertical ground motion. nonlinear soil pressure distribution under basemat, and 3-dimensional behavior of the system shall be included in uplift analysis in order to obtain the correct structural responses.

• Natural Product Sciences
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• v.25 no.4
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• pp.311-316
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• 2019

Artocarpus heterophyllus has been used as traditional medicine. This plant is one of the sources of flavonoid. Flavonoid compounds possessed a wide range of biological properties including anticancer. This study was performed to investigate the cytotoxic effect of flavonoids from A. heterophyllus on H460 and MCF-7 cell lines. The interaction of flavonoids and cisplatin against tested cancer cells was also evaluated. MTT assay was used to determine the cytotoxic effect of flavonoid. Isobologram analysis was selected to evaluate the synergistic effect between flavonoid and cisplatin, their interaction was then confirmed using AO/PI staining method. Amongst of flavonoid compounds, artocarpin exhibited strong cytotoxic effect on both MCF-7 and H460 cell lines with IC₅₀ values of 12.53 ㎍/mL (28.73 μM) and 9.77 ㎍/mL (22.40 μM), respectively. This compound enhanced anticancer activity of cisplatin against H460 and MCF-7. The combination produced a synergistic effect on H460 and MCF-7 cell lines with a combination index (CI) values of 0.2 and 0.18, respectively. The AO/PI stained demonstrated that the combination of artocarpin and cisplatin caused morphological changes that indicated apoptosis. Moreover, artocarpanone also significantly increased cytotoxic effect of cisplatin compared to its single concentration with CI below than 1. This result suggested the potency of flavonoid named artocarpin to enhance the anticancer activity of cisplatin on H460 and MCF-7 cell lines.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.14 no.8
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• pp.3366-3383
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• 2020

The Poisson point process (PPP) is widely used in wireless network modeling and performance analysis because it can provide tractable results for heterogeneous cellular networks (HetNets) analysis. However, it cannot accurately reflect the spatial distribution characteristics of the actual base stations (BSs). Considering the fact that the distribution of macro base stations (MBSs) is exclusive, the deployment of MBSs is modeled by the Matérn hard-core point process (MHCPP), and the deployment of pico base stations (PBSs) is modeled by PPP. This paper studies the performance of multiantenna HetNets and improves the energy efficiency (EE) of HetNets by optimizing the transmit power of PBSs. We use a simple approximate method to study the signal-to-interference ratio (SIR) distribution in two-tier MHCPP-PPP HetNets and derive the coverage probability, average data rate and EE of HetNets. Then, an optimization algorithm is proposed to improve the EE of HetNets. Finally, three transmission technologies are simulated and analyzed. The results show that multiantenna transmission has better system performance than single antenna transmission and that selecting the appropriate transmit power for a PBS can effectively improve the EE of the system. In addition, two-tier MHCPP-PPP HetNets have higher EE than two-tier PPP-PPP HetNets.

• Journal of Life Science
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• v.14 no.5
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• pp.840-846
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• 2004

A study for expression of Korean Mistletoe (KM) lectin gene (A,B) in Saccharomyces cerevisiae was done using transforming system of yeast. In order to overexpress the genes efficiently in yeast, two lectin genes (A,B) were re-cloned and modified including Kozak translation initiation sequence using PCR amplification. The constructed plasmids containing modified lectin A and B genes were transformed to S. cerevisea INVSc (MAT G, his3 $\Delta$1, leu2, trpl-289, ura3-52). The transformed cells were identified by DNA sequencing with ABI3700 system and induced with 2% of galactose for recombinant KM lectin (rKM lectin) protein. The rKM lectin A and B proteins were determinated about 29kDa size of protein by SOS-P AGE and western blotting analysis. The expressed recombinant lectin was determinated 1.24∼1.75 $\mu\textrm{g}$ per 1 mg of cytosolic soluble protein by sandwich ELISA method. Moreover the lectin genes were expressed as maximum level at 36 h after galactose induction and lectin A gene was were repressed after 48 h.

• Asian-Australasian Journal of Animal Sciences
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• v.19 no.10
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• pp.1399-1403
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• 2006

A total of 80 cows, including 40 top mastitis resistant and 40 top mastitis susceptible animals as Group I and Group II, were selected from a population of 520 cows based on clinical mastitis occurrence. PCR-SSCP analysis on four fragments within the 5'region and two fragments of Exons 4,15 of bovine lactoferrin (bLF) revealed that four fragments-P1,P4,E4,E15-had polymorphisms which totally included six base mutations, and only two of them had significant differences in allele frequencies between resistant and susceptible groups, P1 (53.7% vs. 70.0%, p<0.05) and P4 (55.0% vs. 68.8%, p<0.05). Further study on these two promising markers combined with the milk performance traits of cows demonstrated that their selection would result in higher fat percentage (p<0.05), lower Somatic Cell Score (SCS) (p<0.05) and Clinical Mastitis Residuals (CMR) (p<0.01) indicating higher mastitis resistance and lower milk yield (p<0.05). The putative transcription factor binding sites in the 5'region were also studied by using MatInspector 7.2.2 software, and two signal pathways regulating the expression of bLF including the NF-${\kappa}B$ pathway and nuclear hormone receptor pathway were predicted.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.19 no.4
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• pp.67-80
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• 2020

High-speed weigh in motion (HS-WIM) is a real-time unmanned system for measuring the weight of a freight-carrying vehicle while it is in motion without controlling vehicle traffic flow or deceleration. In Korea, HS-WIM systems are installed on the national highways and general national ways for pre-selection by law enforcement. In this study, to improve the measurement accuracy of HS-WIM, we devise improvements to the existing integral and peak weight conversion algorithms, and we provide a new fusion algorithm that can be applied to the mat-type HS-WIM. As a result of analyzing vehicle driving tests at a real site, we confirmed the highest level of weight-measuring accuracy.

• Physical Therapy Rehabilitation Science
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• v.5 no.3
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• pp.113-119
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• 2016

Objective: The effect of abdominal expansion maneuver (AEM) and abdominal draw-in maneuver (ADIM) on postural control in an unsupported position in stroke patients. Design: Randomized controlled trial. Methods: A total of 36 persons with hemiplegic stroke participated in this study. The subjects were randomly divided into an AEM experimental group (n=12), an experimental ADIM group (n=12), and a control group (n=12). We collected the general characteristics of all subjects and the pre-test results before the intervention and after 4 weeks of the intervention. The trunk stabilization training of the ADIM and AEM group were performed 15 minutes a day, 3 times a week for 4 weeks, and general physical therapy was performed 2 times a day, 30 minutes per session, 5 times a week for all three groups. The control group received joint mobilizations, muscle strengthening, endurance strengthening, and gait exercises along with treatment of the central nervous system, such as neuro-developmental treatment, mat, and gait training. The AEM is an inspiratory phase of tidal breathing expanding the lateral lower ribcage in a lateral direction with minimal superior movements of the chest. Then the lower abdomen expands and the navel moves in an anterior-caudal direction. The ADIM is a repeated contraction and relaxation of the anal sphincter during inspiration. The navel pulls the lower abdomen to the direction of the spine without the movement of the trunk and pelvis. Results: Before and after the interventions, medial-lateral axis movement distance, anterior-posterior axis movement distance, sway mean velocity, and sway area 95% was a statistically significant change in all three groups (p<0.05). The post-hoc test showed a significant improvement in medial-lateral axis movement distance, anterior-posterior axis movement distance, sway mean velocity, and sway area in the AEM group compared with the control group, and in the ADIM group compared with the control group (p<0.05). Conclusions: In conclusion, both AEM training and ADIM training are necessary interventions to maintain the independent sitting position according to the characteristics of the patient.