• Title/Summary/Keyword: Mass Line

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LATEST RESULTS OF THE MAXI MISSION

  • MIHARA, TATEHIRO
    • Publications of The Korean Astronomical Society
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    • v.30 no.2
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    • pp.559-563
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    • 2015
  • Monitor of All-sky X-ray Image (MAXI) is a Japanese X-ray all-sky surveyer mounted on the International Space Station (ISS). It has been scanning the whole sky since 2009 during every 92-minute ISS rotation. X-ray transients are quickly found by the real-time nova-search program. As a result, MAXI has issued 133 Astronomer's Telegrams and 44 Gamma-ray burst Coordinated Networks so far. MAXI has discovered six new black holes (BH) in 4.5 years. Long-term behaviors of the MAXI BHs can be classified into two types by their outbursts; a fast-rise exponential-decay type and a fast-rise flat-top one. The slit camera is suitable for accumulating data over a long time. MAXI issued a 37-month catalog containing 500 sources above a ~0.6 mCrab detection limit at 4-10 keV in the region ${\mid}{b}{\mid}$ > $10^{\circ}$. The SSC instrument utilizing an X-ray CCD has detected diffuse soft X-rays extending over a large solid angle, such as the Cygnus super bubble. MAXI/SSC has also detcted a Ne emission line from the rapid soft X-ray nova MAXI J0158-744. The overall shapes of outbursts in Be X-ray binaries (BeXRB) are precisely observed with MAXI/GSC. BeXRB have two kinds of outbursts, a normal outburst and a giant one. The peak dates of the subsequent giant outbursts of A0535+26 repeated with a different period than the orbital one. The Be stellar disk is considered to either have a precession motion or a distorted shape. The long-term behaviors of low-mass X-ray binaries (LMXB) containing weakly magnetized neutron stars are investigated. Transient LMXBs (Aql X-1 and 4U 1608-52) repeated outbursts every 200-1000 days, which is understood by the limit-cycle of hydrogen ionization states in the outer accretion disk. A third state (very dim state) in Aql X-1 and 4U 1608-52 was interpreted as the propeller effect in the unified picture of LMXB. Cir X-1 is a peculiar source in the sense that its long-term behavior is not like typical LMXBs. The luminosity sometimes decreases suddenly at periastron. It might be explained by the stripping of the outer accretion disk by a clumpy stellar wind. MAXI observed 64 large flares from 22 active stars (RS CVns, dMe stars, Argol types, young stellar objects) over 4 years. The total energies are $10^{34}-10^{36}$ erg $s^{-1}$. Since MAXI can measure the spectrum (temperature and emission measure), we can estimate the size of the plasma and the magnetic fields. The size sometimes exceeds the size of the star. The magnetic field is in the range of 10-100 gauss, which is a typical value for solar flares.

Method Development for the Profiling Analysis of Urine Globotriaosylceramide (Gb3) for the Screening of Fabry Disease by Tandem Mass Spectrometry (ESI-MS/MS를 이용한 소변 중 Globotriaosylceramide(Gb3)의 정량 및 임상 응용; 패브리병(Fabry) 진단)

  • Yoon, Hye-Ran;Cho, Kyung-Hee;Kang, Seung-Woo;Kwon, Young-Joo;Jeong, Choon-Sik;Lee, Yong-Soo
    • YAKHAK HOEJI
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    • v.51 no.2
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    • pp.96-102
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    • 2007
  • Measurement of globotriaosylceramide (Gb3, ceramide trihexoside) in urine has clinical importance for monitoring after enzyme replacement therapy in Fabry disease patients. The disease is an X-linked lipid storage disorder that results from a deficiency of the enzyme ${\alpha}$-galactosidase A (${\alpha}$-Gal A). The lack of ${\alpha}$-Gal A causes an intracellular accumulation of glycosphingolipids, mainly Gb3. A simple, rapid, and highly sensitive analytical method for Gb3 in urine was developed without labor-extensive pre-treatment by electrospray ionization MS/MS (ESI-MS/MS). Only simple 5-fold dilution of urine is necessary for the extraction and isolation of Gb3 in urine. Gb3 in diluted urine was dissolved in dioxane containing C17:0 Gb3 as an internal standard. After centrifugation it was directly injected and analyzed through guard column by in combination with multiple reaction monitoring mode of ESI-MS/MS. Eight isoforms of Gb3 were completely resolved from urine matrix. C24:0 Gb3 occupied 50% of total Gb3 as a major component in urine. Linear relationship for Gb3 isoforms was found in the range of 0.005${\sim}$5.0 ${\mu}$g/ml. The limit of detection (S/N=5) was 0.005 ${\mu}$g/ml and limit of quantification was 0.05 ${\mu}$g/ml for C24:0 Gb3 with acceptable precision and accuracy. Correlation coefficient of calibration curves for 8 Gb3 isoforms ranged from 0.9598 to 0.9975. This method could be useful for rapid and sensitive 1st line Fabry disease screening, monitoring and/or diagnostic tool for Fabry disease.

Study on the design optimization of injection-molded DVD-Tray parts using CAE Simulation (플라스틱 DVD-Tray의 박막 사출성형을 위한 최적화 설계 Simulation에 관한 연구)

  • Chung, Jae-Youp;Kim, Dong-Hak
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.9 no.6
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    • pp.1726-1732
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    • 2008
  • Injection molding is one of plastic forming technology which can easily mass-produce plastic parts with various and even complex shape. The technology has lots of difficulties in making a good part due to phase change of material, high applied pressure, and fast melt flow speed in the cavity. To overcome the problems, they had to make trial and error method until the CAE(Computer Aided Engineering) could be a tool for concurrent engineering. In this paper, we investigate the optimal design for a plastic DVD tray part by systematic approach of the commercial CAE program. In design, we should consider two objectives which are both dimensional stability and cost-down. The dimension of the part is crucial because the tray should carry a DVD correctly, but the part is too thin to injection-mold easily. In order to improve the moldability, the mold is designed in the form of stack mold which is a kind of 4 hot runner system. In first, we changed the stack-mold system with one hot-runner to cost down, and decided the optimal position of the gate. After that, we investigate the effect of both the layout of cooling channels and the cooling temperature on the shrinkage of the DVD tray. A optimal simulation approach, the gate design is 2Gate#3 and the layout is Case2 cooling line as the optimal temperature of $70^{\circ}C$. The Moldflow and PC+ABS are used for the CAE program and material respectively.

Sterol Composition and Phytoestrogen Activity of Safflower(Carthamus tinctorius L.) Seed (홍화(Carthamus tinctorius L.)씨의 sterol 및 Phytoestrogen 분석)

  • 최영주;최상욱
    • Journal of Life Science
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    • v.13 no.4
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    • pp.529-534
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    • 2003
  • This study was done to investigated the phytosterol compositions of safflower (Carthamus tinctorius L.) seed. The phytoestrogen activity was also determined using CAT-ELISA Kit in ethanol extract of safflower seed. The phytosterol of safflower seeds was identified using gas chromatography-mass spectrometry after saponification of the oils. The phytosterol content and composition of safflower seed oils were 4% and identified stigmast-5-en-3-ol (3$\beta$, 24S)-form, ${\gamma}$-sitosterol (clionasterol) with Wiley MS spectrum library. The synergistic effect of human estrogen receptor (hER) has been investigated using a minimal chimeric promoters composed of the TATA region of the adenovirus-2 major late promoter (A22MLP) and two consensus perfectly polindromic Xenopus vitellogenin A2 gene estrogen responsive elements (XVEREl19). Transient transfection experiments in tile human breast adenocarcinoma cell line MCF-7, which is known to express the estrogen receptor endogenously, revealed that phytoestrogen from Carthamus tinctorius L. acts as estrogen. We have observed the transcriptional activities stimulated methanol and ethanol extract of safflower seed in MCF-7, were 0.43 and 0.37 respectively, compared to that by $\beta$-estradiol as 1.0. Our data showed that safflower seeds have estrogenic activity methanol and ethanol extracts and ethanol lower than that of $\beta$-estradiol. This result provides the first evidence that the beneficial effect of safflower seeds may be mediated, at least in part, by the stimulating effect of phytoestrogen ell bone-protecting.

Development of Outer Support Ring using Complex Forging Processes (복합단조 공정을 적용한 Outer Support Ring 개발)

  • Ju, Won Hong;Park, Sung-young
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.4
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    • pp.653-659
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    • 2017
  • In this study, the complex forging process of an outer support ring was developed and the prototype was manufactured. The current process, hot forging and MCT machining, has a disadvantage of excessive material removal rates and longer machining hours. To overcome this disadvantage, a general shape is given through hot forging and the precision is achieved through cold forging. The complex forging process was developed with the minimal machining process. Forging analysis was carried out to design a forging process using the commercial program, Deform-3D. The hot and cold forging processes were set up based on the analyzed result. The mold and prototype were manufactured. Hardness, surface roughness, internal defect, the grain low line of the prototype were evaluated. The results showed no particular problems, and there were no problems in mass production. Using complex forging, the material was reduced by approximately 27 % compared to the process using hot forging and MCT machining. In addition, the production speed was improved 2.15 fold compared to that of hot forging and MCT machining. Through this study, a cost-effective process and mold design technology were established, which is expected to have positive effects on other related automotive parts production.

A New Early-Heading and High Forage Yielding Rye Variety "Egreen" (극조숙, 다수성 조사료 및 녹비용 호밀 신품종 "이그린")

  • Heo, Hwa-Young;Park, Hyoung-Ho;Hwang, Jong-Jin;Kim, Hong-Sik;Han, Ouk-Kyu;Park, Tae-Il;Seo, Jae-Hwan;Kim, Dea-wook;Kim, Su-Yong;Kim, Si-Ju;Park, Ki-Hun
    • Korean Journal of Breeding Science
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    • v.41 no.4
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    • pp.620-624
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    • 2009
  • "Egreen" rye (Secale cereale L.) was developed by National Institute of Crop Science (NICS), RDA. It was released in 2007 because of its excellent earliness and yield potential. Crossing was made by an open pollination with 10 rye lines in 1995. Many lines from the open pollinated population were handled in a mass selection program in subsequent generations. Among them the line 'SR95POP-S1-116-1-1-2'was selected for earliness and promising agronomic appearance and placed in yield trial for two years from 2003 to 2004. In 2005, it was designated "Homil 34" and subjected to regional yield trials. Over 3 years, "Egreen" averaged 8.34 MT ha-1 of forage yield (based on dry matter) harvested at the heading date of check variety "Olhomil", which was superior to other varieties such as "Olhomil" and "Koolgrazer" with an increase of 8% and 10%, respectively. Heading date of "Egreen" was April 22, 3 days earlier than that of "Olhomil". It would be recommended as a winter crop forforage and green manure before planting either maize or rice in Korea.

The estimation of Draize score by in vitro cytotoxicity using continuous cell lines (In Vitro cytotoxicity에 의한 Draize score 측정 체계 수립)

  • 정민석;최종완
    • Proceedings of the SCSK Conference
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    • 1996.07a
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    • pp.33-51
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    • 1996
  • 화장품의 변질요인은 크게 물리적 또는 화학적 변화에 의한 요인과 미생물오염으로 인한 각종 문제점으로 대별될 수 있다. 이 중에서 미생물 오염문제는 제품의 상품가치에 미치는 영향 뿐만 아니라 지속적인 사용에 의한 피부의 위생적 측면때문에 그 중요성에 대한 인식이 높아지고 있다. 따라서, 제품개발시는 화장품 처방중의 영양성분의 배합, pH, 유화형태, 방부제의 혼합, 분배계수 및 그 안정성을 고려하여야 함은 물론이고 처방중의 모든 원료의 각각에 대한 항균능 및 피부자극여부를 사전에 미리 조사하여 각 제품별로 적당한 방부체계를 선택하는 것은 매우 중요한일이다. 독성실험방법에 있어서 in vivo 실험에 대체할 수 있는 새로운 in vitro 실험방법 수립 즉, 동물실험을 하지 않고 in vitro 실험결과로부터 in vivo 결과를 예측할 수 있도록 새로운 in vitro 실험체계의 가능성을 실험하였다. 4종의 cell line중 transformed mouse fibroblast L929가 본 실험에서 사용하기에 배양상의 용이성과 안정성, 재현성의 관점에서 가장 알맞은 cell line이었다. transformed mouse fibroblast L929를 사용한 NR$_{50}$ assay와 Draize score간의 regression coefficient ${\gamma}$값은 0.91이었다. 혈청은 시험물질의 세포에 대한 민감성에 영향을 주었다. 따라서, modified serum-free method를 이용함으로써 regression coefficient가 증가된 즉, 상관성 및 재현성이 높은 결과를 얻을 수 있었다. 이러한 기술은 독성실험에 실험동물을 사용하지 않고 in vivo test에 대체 할 수 있고, 또한 화학물질에 대한 prescreening으로 이용할 수 있을 것으로 판단된다.원과 섭식장소, 수중생물의 경우는 특히 수온, 수량 영양원등이다.(중략). 본 연구의 접근방법으로는 ASRS의 개념적인 Reference Model을 수립하고 이 Reference Model에 대한 Formal Model로 DEVS(Discrete Event System Specification)을 이용하여 시스템을 Modeling하였다. 이의 Computer Simulation을 위하여 DEVS형식론 환경에서의 Simulation Language인 DEVSim ++ⓒ를 이용하여 시스템을 구현하였다.. 실형 결과로는 먼저 선형 상미분방정식의 예로 mass-damper-spring system, 비선형 상미분방정식의 예로는 van der Pol 방정식, 연립 상미분방정식의 예로는 mixing tank problem 등을 보였으며, 그의 공학에서 일어나는 여러 가지 문제들도 다루었다.화물에 대한 방어력이 증가되어 나타난 결과로 여겨지며, 또한 혈청중의 ALT, ALP 및 LDH활성을 유의성있게 감소시키므로서 감잎 phenolic compounds가 에탄올에 의한 간세포 손상에 대한 해독 및 보호작용이 있는 것으로 사료된다.반적으로 홍삼 제조시 내공의 발생은 제조공정에서 나타나는 경우가 많으며, 내백의 경우는 홍삼으로 가공되면서 발생하는 경우가 있고, 인삼이 성장될 때 부분적인 영양상태의 불충분이나 기후 등에 따른 영향을 받을 수 있기 때문에 앞으로 이에 대한 많은 연구가 이루어져야할 것으로 판단된다.태에도 불구하고 [-wh]의미의 겹의문사는 병렬적 관계의 합성어가 아니라 내부구조를 지니지 않은 단순한 단어(minimal $X^{0}$ elements)로 가정한다. 즉, [+wh] 의미의 겹의문사는 동일한 구성요 소를 지닌 병렬적 합성어([$[W1]_{XO-}$ $[W1]_{XO}$ ]

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A Scientific Analysis of Gold Threads Used in Donggungbi-Wonsam(Ceremonial Robe Worn by a Crown Princess, National Folklore Cultural Heritage No.48) (동궁비 원삼에 사용된 금사의 과학적 분석)

  • Lee, Jang-Jon;An, Boyeon;Han, Kiok;Lee, Ryangmi;Yoo, Ji Hyun;Yu, Ji A
    • Journal of Conservation Science
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    • v.37 no.5
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    • pp.525-535
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    • 2021
  • This study identified material properties through scientific analysis on Jikgeumdan(satin with gold threads) from Donggungbi-Wonsam and the gold threads used in the embroidery. The Donggungbi-Wonsam's base of gold threads were estimated to have used mulberry fiber's Korean paper(Hanji) because non-wood-based fibers were observed. The X-ray spectrometer showed that the Tongsuseulan of Donggungbi-Wonsam was a flat gold thread of pure gold and Jikgeumdan of flat silver thread of its Saekdong and Hansam. High sulfur levels were detected in the flat silver thread, which appeared to have formed silver sulfide by either manufacturing process using sulfur or conservation environment. he dragon insignia's embroidery is also described as two types twisted gold threads; pure gold and alloying-gold and silver. while dragon insignia's border line is decorated with a twisted gold thread of pure gold. In particular, it was investigated that adhesives such as an animal glue, a protein-based compound by gas chromatography mass spectrometry. Additionally, XRF and Raman spectroscopy analysis on the mixture substances between the metal surface and the base paper of gold threads identified talc and quartz in the gold threads and Seokganju(hematite) in the flat silver threads.

Analysis of Korean News Report: Focusing on N. Korea-Russia Summit (국내 언론 보도 연구: 북-러 정상회담을 중심으로)

  • Ban, Hyun
    • The Journal of the Convergence on Culture Technology
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    • v.5 no.2
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    • pp.117-122
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    • 2019
  • This paper aims to investigate ideological preferences of news media outlets by looking at the news coverage of North Korea-Russia summit in April, 2019. The meeting has gained attention in South Korea, China, Japan and America in that the historical meeting will reflect the future direction for denuclearization on the Korean peninsular and the peace in the world. Given this, in particular, a special attention is paid to the editorials and headlines of news articles reported in two Korean quality newspapers, DongA Ilbo and Hankyoreh because both are quality newspapers, but are ideologically different. To achieve objectivity and fairness, the same issues dealt with during the summit were compared and analyzed within Martin and White (2005)'s Appraisal framework. As a result, it was found that in editorials of DongA Ilbo showed a negative stance to the summit by employing the 'attitude' factor, whereas the Hankyoreh was overwhelmingly positive toward the issue, also by employing the 'attitude' factor. The political stance is likely to be in line with those shown in the headlines of news articles from each newspaper. That is, it is clear that each news outlet shows its ideological stances to news consumers through linguistic expressions, in that both editorials and the headlines of news articles express their political preferences to the summit by means of linguistic appraisals.

Oedipa's Quest and Two Americas (에디파의 탐구와 두 개의 미국)

  • Son, Dongchul
    • English & American cultural studies
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    • v.9 no.1
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    • pp.273-295
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    • 2009
  • As Oedipa Mass, the heroine of Thomas Pynchon's The Crying of Lot 49, is apparently associated with Oedipus, the hero in Sophocles' tragedy, this paper aims to show some of their similarities in quest theme and plot development as well as in the use of dramatic irony. Oedipus the King opens with a priest's pleas to relieve the Theban people from a plague and the king's promise to rid its cause by avenging the murder of the former king, as told by the oracle. Lot 49 begins as a Los Angeles law firm informs Oedipa that she is named as the executrix in her former lover Inverarity's will to sort out the mogul's estate. Ironically, however, Oedipus' investigation reveals himself to be the very cause of the national disaster, the murderer for whom he searched. Likewise, Oedipa starts her inquiry dedicating herself to make sense out of what Inverarity had left behind, only to find that the legacy was America. Sophocles and Pynchon both employ dramatic irony to provide a controlling principle for plot development in their works. In Oedipus the King, Sophocles creates mounting tension as well as distance between the reader's knowledge and the protagonist's ignorance, compressing the play's action into the moment that Oedipus discovers his real identity. For dramatic irony, however, Pynchon tends to work through authorial comments and utilize allegorical meanings of the characters' names, directing his novel at illuminating Oedipa's discovery of Inverarity's legacy as well as the meaning of Tristero, an underground postal service system. Unlike Oedipus the King that proceeds on a single line of action, Lot 49 develops in esoteric, multi-layered allusions and intricately-interrelated double strains involving Oedipa's roles as executrix and quester. At the end of Sophocles' tragedy, Oedipus stabs his eyes and decides to live in exile, realizing that, blinded, he begot his children through his mother; Oedipa comes to a painful realization that she allowed her former lover to create death-orienting America without her diversity and moral system in old times. As Oedipa now discovers herself through her search for Tristero, her tragic spirit lies in her determination to confront her binary choices between two Americas: transcendence or entropy, the Tristero possibility or Inverarity's America. Ultimately, Oedipa tries to find who will be the bidder for the Tristero forged stamps designated as lot 49, awaiting the auctioneer's cry and the "crying" of a new-born America.