• Title/Summary/Keyword: Mass Extinction

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Comparative analysis of urinary metabolites in methamphetamine self-administrated rats

  • Choi, Boyeon;Kim, Soo Phil;Jang, Choon-Gon;Yang, Chae Ha;Lee, Sooyeun
    • Analytical Science and Technology
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    • v.30 no.3
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    • pp.122-129
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    • 2017
  • Methamphetamine addiction is a critical issue due to the lack of effective pharmacotherapy and high potential for relapse. Nevertheless, there are no distinct biomarkers for diagnosis or prognosis for methamphetamine addiction. In the present study, a rat model for methamphetamine self-administration was established and alteration of urinary metabolites by methamphetamine addiction was investigated by the targeted metabolite analysis using mass spectrometry. Rat urine samples were collected at three time points (before and after addiction and after extinction) from the methamphetamine-addicted group as well as the age-matched control group. The collected samples were prepared using AbsoluteIDQ p180 kit and analyzed using flow injection analysis (FIA) - or high performance liquid chromatography (HPLC) - tandem mass spectrometry (MS/MS). The levels of lysine, acetylornithine and methioninesulfoxide were distinctively altered depending on the status of metheamphetamine addiction or extinction. In particular, the level of acetylornithine was reversely changed from addiction to extinction, for which further studies could be useful for biomarker discovery or mechanistic studies for methamphetamine addiction.

Numerical Study on Methane/Air Turbulent Jet Diffusion Flames Near-Extinction Using Conditional Moment Closure Model (CMC model에 의한 near-extinction methane/air turbulent jet diffusion flame의 수치적 모사)

  • Kang, Seung-Tak;Kim, Seung-Hyun;Huh, Kang-Yul
    • 한국연소학회:학술대회논문집
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    • 2002.11a
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    • pp.11-17
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    • 2002
  • The first-order conditional moment closure (CMC) model is applied to $CH_4$/Air turbulent jet diffusion flames(Sandia Flame D, E and F). The flow and mixing fields are calculated by fast chemistry assumption and a beta function pdf for mixture fraction. Reacting scalar fields are calculated by elliptic CMC formulation. The results for Flame D show reasonable agreement with the measured conditional mean temperature and mass fractions of major species, although with discrepancy on the fuel rich side. The discrepancy tends to increase as the level of local extinction increases. Second-order CMC may be needed for better prediction of these near-extinction flames.

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The Characteristics of Soot at the Post-Flame Region in Jet Diffusion Flames Added Carbon Dioxide (이산화탄소가 첨가된 제트확산화염 후류에서의 매연 특성)

  • Ji, Jung-Hoon;Lee, Eui-Ju
    • Journal of the Korean Society of Safety
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    • v.25 no.6
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    • pp.9-13
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    • 2010
  • An experimental study for characteristics of soot were conducted at the post-flame region in jet diffusion flames, where carbon dioxide was used as additives in oxidizer stream. Light-extinction method was performed using He-Ne laser with wave length at 632.8nm for the measurement of relative soot density and soot volume fraction with dimensionless extinction coefficient, $K_e$ and mass specific extinction coefficient, ${\sigma}_s$. To increase of resolution, laser light was modified for sheet-form using concave, convex lenses and slit. C/H ratio was introduced for quantitative analysis of soot growth which is expressed by carbonization and dehydrogen. Also transmission electron microscopy(TEM) was used for observation of morphological shape. The results show that the relative soot density in the post-flame region was lower when carbon dioxide was added in oxidizer stream because of reduction of flame temperature.

Vertical Change in Extinction and Atmospheric Particle Size in the Boundary Layers over Beijing: Balloon-borne Measurement

  • Chen, Bin;Shi, Guang-Yu;Yamada, Maromu;Zhang, Dai-Zhou;Hayashi, Masahiko;Iwasaka, Yasunobu
    • Asian Journal of Atmospheric Environment
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    • v.4 no.3
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    • pp.141-149
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    • 2010
  • Aerosol size and number concentration were observed in the atmospheric boundary layer over Beijing (from near the ground to 1,200 m) on March 15 (a clear day) and 16 (a dusty day), 2005. The results were further compared with lidar measurements in order to understand the dependency of extinction on the particle size distribution and their vertical changes. The boundary layer atmosphere was composed of several sub-layers, and a dry air layer appeared between 400 and 1,000 m under the influence of dust event. In this dry air layer, the concentration of the fine-mode particles (diameter smaller than $1.0\;{\mu}m$) was slightly lower than the value on the clear day, while the concentration of coarse-mode particles (diameter larger than $1.0\;{\mu}m$) was remarkably higher than that on the clear day. This situation was attributed to the inflow of an air mass containing large amounts of Asian dust particles and a smaller amount of fine-mode particles. The results strongly suggest that the fine-mode particles affect light extinction even in the dusty atmosphere. However, quantitatively the relation between extinction and particle concentration is not satisfied under the dusty atmospheric conditions since laser beam attenuates in the atmosphere with high concentration of particles. Laser beam attenuation effect becomes larger in the relation between extinction and coarse particle content comparing the relation between extinction and fine particle content. To clarify this problem technically, future in situ measurements such as balloon-borne lidar are suggested. Here extinction was measured at 532 nm wavelength. Measurements of extinction at other wavelengths are desired in the future.

Comparison between a Light-Scattering and a Light-Extinction Methods for the Study on Soot Yielding Characteristics of an Electric Cable Fire (전선 매연 생성 특성 연구를 위한 광산란법-광소멸법의 비교)

  • Cho, Sang-Moon;Lee, Min-Jung;Kim, Nam-Il
    • Journal of the Korean Society of Safety
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    • v.23 no.6
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    • pp.38-43
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    • 2008
  • Significant portion of the fire accident is caused by some troubles in electric circuits. To prevent the fire induced by those electric trouble, some indications of electric fire need to be suitably detected at the first stage of the fire development. With this background, the characteristics of soot yielding of electric cables have been investigated using a light extinction method. In this study, a light scattering method was compared with the light extinction method. A slot-type premixed-flame combustor was traversed to bum three types of electric cables by compulsion, then the mass decrease rate and the soot densities were measured. According to the experimental results, the light scattering method is preferred to the light extinction method when the soot yield ratio is relatively small. Thus the former method is more suitable to detect the occurrence of an electric fire in a power distributer box.

The New Mass Estimator of Black Hole in Active Galaxies with Near Infrared Hydrogen Line

  • Kim, Do-Hyeong;Im, Myeong-Sin;Kim, Min-Jin
    • The Bulletin of The Korean Astronomical Society
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    • v.35 no.1
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    • pp.80-80
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    • 2010
  • About 50% of Active Galactic Nuclei(AGNs) are found to be red and dust-obscured. They are believed to be in an early dusty stage of AGNs evolution or affected by dust torus in the direction of line of sight. However, optical spectrum is affected by dust extinction, making it difficult to study their properties, such as FWHM and luminosity. In order to reveal the mass of central Black Hole(BH) in red AGN, we establish a new BH mass estimator for typical type1 AGNs using Near InfraRed(NIR) hydrogen line($P_{\alpha}$ and $P_{\beta}$), since these lines are at longer wavelength, less affected by dust extinction than optical hydrogen lines, such as $H_{\alpha}$ and $H_{\alpha}$. To derive the new empirical formula, we use a sample of well-known 36 AGN with a wide BH mass range of $10^6-10^9\;M_{\odot}$, where $M_{BH}s$ are estimated by reverberation mapping method and single epoch method. The $P_{\alpha}/P_{\beta}$ luminosities and FWHMs are derived by analyzing IRTF NIR spectra or taken from literature values. We show that luminosities and FWHMs of these lines correlate well with those of Balmer lines. Suggesting that Paschen and Balmer broad lines are originated from same region. Finally, we present the new $M_{BH}$ formula that are based on $P_{\alpha}/P_{\beta}$ luminosity and FWHM. We hope that our result will be used for investigating red AGNs.

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Determination of some useful radiation interaction parameters for waste foods

  • Akman, F.;Gecibesler, I.H.;Sayyed, M.I.;Tijani, S.A.;Tufekci, A.R.;Demirtas, I.
    • Nuclear Engineering and Technology
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    • v.50 no.6
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    • pp.944-949
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    • 2018
  • The mass attenuation coefficients (${\mu}/{\rho}$) of food waste samples (pomegranate peel, acorn cap, lemon peel, mandarin peel, pumpkin peel, grape peel, orange peel, pineapple peel, acorn peel and grape stalk) have been measured employing a Si(Li) detector at 13.92, 17.75, 20.78, 26.34 and 59.54 keV. Also, the theoretical values of the mass attenuation coefficients have been evaluated utilizing mixture rule from WinXCOM program. The results showed that the lemon peel has the highest values of ${\mu}/{\rho}$ among the selected samples. From the obtained mass attenuation coefficients, we determined some absorption parameters such as effective atomic number ($Z_{eff}$), electron density ($N_E$) and molar extinction coefficient (${\varepsilon}$). It was found that the $Z_{eff}$ values of all food wastes lie within the range of 4.034-7.595, whereas the $N_E$ of the studied food wastes was found to be in the range of $0.301-1.720{\times}10^{25}$ (electrons/g) for present energy region.

Characteristics of Visibility Impairment by Semi-Continuous Optical and Chemical Property Monitoring of Aerosols in Seoul (에어로졸의 광학 및 화학 특성 준실시간 모니터링을 통한 서울지역 시정 감쇄 분석)

  • Park, Jong-Sung;Park, Seung-Myung;Song, In-Ho;Shin, Hye-Jung;Hong, You-Deog
    • Journal of Korean Society for Atmospheric Environment
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    • v.31 no.4
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    • pp.319-329
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    • 2015
  • The characteristics of aerosol light extinction were investigated by comparing measured and calculated extinction coefficient to understand the contribution of air pollutants on visibility impairment for data during 4 months (Jan~ April), 2014. The integrated nephelometer and aethalometer system were installed to measure the scattering and absorption coefficients of aerosol as well as BAM 1020, MARGA, semi-continuous OCEC analyzer, and online-XRF to calculate the extinction coefficient. The IMPROVE_2005 equation was used to determine the contributions of different chemical components on visibility impairment in $PM_{2.5}$ and $PM_{10}$ due to highest correlation with measured data. Sulfate, nitrate, and organic mass by carbon (OMC) of fine aerosol were the major contributors affecting on visibility impairment. Total contributions to light extinction were calculated as $631.0Mm^{-1}$ for the worst-case and $64.4Mm^{-1}$ for the best-case. The concentrations of aerosol component for the worst-case were 38.4 times and 45.5 times larger than those of the best-case for $(NH_4)_2SO_4$ and $NH_4NO_3$, respectively. At lower visibility condition, in which extinction coefficient was higher than $400Mm^{-1}$, extinction coefficient varied according to the relative humidity variation regardless of $PM_{2.5}$.

The KALION Automated Aerosol Type Classification and Mass Concentration Calculation Algorithm (한반도 에어로졸 라이다 네트워크(KALION)의 에어로졸 유형 구분 및 질량 농도 산출 알고리즘)

  • Yeo, Huidong;Kim, Sang-Woo;Lee, Chulkyu;Kim, Dukhyeon;Kim, Byung-Gon;Kim, Sewon;Nam, Hyoung-Gu;Noh, Young Min;Park, Soojin;Park, Chan Bong;Seo, Kwangsuk;Choi, Jin-Young;Lee, Myong-In;Lee, Eun hye
    • Korean Journal of Remote Sensing
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    • v.32 no.2
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    • pp.119-131
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    • 2016
  • Descriptions are provided of the automated aerosol-type classification and mass concentration calculation algorithm for real-time data processing and aerosol products in Korea Aerosol Lidar Observation Network (KALION, http://www.kalion.kr). The KALION algorithm provides aerosol-cloud classification and three aerosol types (clean continental, dust, and polluted continental/urban pollution aerosols). It also generates vertically resolved distributions of aerosol extinction coefficient and mass concentration. An extinction-to-backscatter ratio (lidar ratio) of 63.31 sr and aerosol mass extinction efficiency of $3.36m^2g^{-1}$ ($1.39m^2g^{-1}$ for dust), determined from co-located sky radiometer and $PM_{10}$ mass concentration measurements in Seoul from June 2006 to December 2015, are deployed in the algorithm. To assess the robustness of the algorithm, we investigate the pollution and dust events in Seoul on 28-30 March, 2015. The aerosol-type identification, especially for dust particles, is agreed with the official Asian dust report by Korean Meteorological Administration. The lidar-derived mass concentrations also well match with $PM_{10}$ mass concentrations. Mean bias difference between $PM_{10}$ and lidar-derived mass concentrations estimated from June 2006 to December 2015 in Seoul is about $3{\mu}g\;m^{-3}$. Lidar ratio and aerosol mass extinction efficiency for each aerosol types will be developed and implemented into the KALION algorithm. More products, such as ice and water-droplet cloud discrimination, cloud base height, and boundary layer height will be produced by the KALION algorithm.