• Title/Summary/Keyword: Masculinization

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Sex Reversal and Masculinization according to Growth in Longtooth Grouper Epinephelus bruneus

  • Oh, Seong-Rip;Kang, Hyeong-Cheol;Lee, Chi-Hoon;Hur, Sang-Woo;Lee, Young-Don
    • Development and Reproduction
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    • v.17 no.2
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    • pp.79-85
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    • 2013
  • To understand the sex reversal characteristics in the longtooth grouper (Epinephelus bruneus), this study examined the sex reversal and artificial masculinization of wild caught E. bruneus reared in indoor rearing tank after a 17${\alpha}$-methyltestosterone injection. To domesticate a broodstock, 64 wild caught E. bruneus, between 47.0 to 110.0 cm in total length and from 1.5 to 21.4 kg in body weight, were reared in indoor rearing tank (4.0 to 5.0 m wide, and 2.5 to 3.0 m depth) for four years. Seven specimens showed sex reversal from female to male during indoor rearing condition, whose total length and body weights were from 63.0 to 99.0 cm and from 4.4 to 13.2 kg, respectively. After inducing artificial masculinization in 14 female E. bruneus with a 17${\alpha}$-methyltestosterone (2.0 mg/kg BW) implants for 3 years, spermiation occurred in 9 specimens (total length: 54.0 to 68.0 cm, body weight: 2.3 to 4.3 kg). Among the female to male sex reversals, two specimens returned back to being female, whose body weights were 2.8 kg (initially 2.6 kg) and 2.7 kg (initially 2.3 kg). Therefore, this study suggested that E. bruneus (> 3.0 kg) was more effective in masculinizing by 17${\alpha}$-methyltestosterone implants.

Masculinization of Femininity: A Gender-Based Reading of Đoạn tuyệt [Breaking Off] by Nhất Linh

  • TOAN, TRAN VAN
    • SUVANNABHUMI
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    • v.5 no.2
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    • pp.81-99
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    • 2013
  • Đoạn tuyệt is the representative of not only Nhất Linh's literary life but also of the Tự Lực Văn Đoàn [Self-Strength Literary Group]. Đoạn tuyệt's contributions are emphasized in the following aspects: 1) critique of the feudal family model, 2) an advocate of female and individual liberation, 3) nationalistic content, though rather vague. Based on analysis of gender power relations in the masculinization of femininity exemplified in the character Loan of the novel, this paper addresses the following points: - In Đoạn tuyệt, the woman is eager to free herself from feudalist ties not to construct her own identity but to identify her with men's identities. - The construction of new feminine identities was conditioned in new rising discourses of Western modernity-based nationalisms in pre-revolutionary Vietnam. - The feminization of masculinity echoes the crisis of Vietnamese masculine in facing colonial power.

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A sclerosing stromal tumor of the ovary with masculinization in a premenarchal girl

  • Park, Soo-Min;Kim, Young-Nam;Woo, Young-Jong;Choi, Ho-Sun;Lee, Ji-Shin;Heo, Suk-Hee;Kim, Chan-Jong
    • Clinical and Experimental Pediatrics
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    • v.54 no.5
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    • pp.224-227
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    • 2011
  • A sclerosing stromal tumor of the ovary is an extremely rare benign tumor; it usually is found during the second and third decades of life. Patients present with pelvic pain or a palpable abdominal mass. Hormonal effects such as masculinization are uncommon. Here, an 11-year old premenarchal girl presented with deepening of the voice. In addition, clitoromegaly and hirsutism with a male suprapubic hair pattern were observed. The laboratory findings showed that the testosterone level was elevated to 3.67 ng/ml, andostenedione to above 10 ng/ml, dehydroepiandrosterone-sulfate to 346 ${\mu}g$/dl and 17-hydroxy progesterone (17-OHP) to 11.28 ng/ml. The chromosome evaluation revealed a 46,XX female karyotype. An adrenocorticotropic hormone stimulation test was performed. The 17-OHP to cortisol ratio in 30 minutes was 0.045, which suggested a heterozygote for the 21-hydroxylase deficiency. However, the CYP21A2 gene encoding steroid 21-hydroxylase showed normal. The pelvic ultrasound showed a heterogeneous mass consisting of predominantly solid tissue in the pelvic cavity. The pelvic magnetic resonance imaging revealed an $8.9{\times}6.2{\times}6.6$ cm mass of the left ovary. A left oophrectomy was performed and microscopic examination confirmed a sclerosing stromal tumor. Immunohistochemical studies showed that the tumor was positive for smooth muscle actin and vimentin, but negative for S-100 protein and cytokeratin. Following surgery, the hormone levels returned to the normal range and the hirsutism resolved.

Immersion in sea cucumber's steroid extract to increase male production of juvenile freshwater crayfish

  • Gregorius Nugroho Susanto;Endang Linirin Widiastuti;Tri Rustanti;Sutopo Hadi
    • Fisheries and Aquatic Sciences
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    • v.26 no.1
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    • pp.48-57
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    • 2023
  • One of the ways to increase the production for aquaculture is through the cultivation of monosexuals by ensuring genital reversal from which energy for reproduction is diverted towards growth. Masculinization has been identified as one of the most prominent techniques, where sex development was directed from female to male. This approach only altered the phenotype and not the genotype. The red claw crayfish (Cherax quadricarinatus) was a relatively new commercial commodity, and the males were known to grow faster than females. Hence, it was proposed to use monocultures comprising an all-male population to increase yield using steroid hormone, synthetic 17α-methyltestosterone. However, this technique generated residues that detrimentally affect human health, the environment, and cultivated organisms. Therefore, finding new safe natural steroid sources was essential, and one of which is exploring of natural hormones extracted from the viscera of sea cucumbers (Holothuria scabra Jaeger). This study focused on the determination of male formation and testosterone levels among juvenile crayfish, after immersing in sea cucumber steroid extract (SCSE). A completely random design with factorial was used with two variables, encompassing the varied doses (0, 2, 4 mg/L, 2 mg/L 17α-methyl testosterone as control group) and immersion times of 18 and 30 h. The result showed the dose-dependent ability of SCSE increase the male genital formation and promote the testosterone level of juvenile crayfish. In addition, the testosterone was influenced by dose and immersion duration time, with the highest level of testosterone observed in treatments of 4 mg/L SCSE with 30 h immersion was 0.248 ng/mL, while the male percentage was 77%. In conclusion, the combination of dose and immersion time significantly affected growth and testosterone levels.

A Study on the Influence Made by the Women's Emancipation Movement ($1850\~1950$) on Western Clothing (여성해방운동이 서양복식에 미친 영향에 관한 연구($1850\~1950$))

  • Kwak Mi Young;Jung Hung Sook
    • Journal of the Korean Society of Clothing and Textiles
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    • v.15 no.3 s.39
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    • pp.239-250
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    • 1991
  • The purpose of this study was primarily aimed at the revealing changes in the aspects of women's clothing derivationed with the women's self-consciousness, liberation movement, women's suffrage and social participation from the mid-l9th century to the mid-20th century. According to the study, the main change of western women's costumes were eradication of corset, emergence of troussers and tailored suit, and transformation of sportwear. So that, women's liberation movement has an deep effect on leading up to a change tendency the functionalization and masculinization of women's costume.

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Thorax masculinization in a transsexual patient: Inferior pedicle mastectomy without an inverted T scar

  • Cely, Adriana Marcela Gonzalez;Triana, Carlos Enrique;Triana, Lina Maria
    • Archives of Plastic Surgery
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    • v.46 no.3
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    • pp.262-266
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    • 2019
  • Transsexual individuals with gender dysphoria or gender identity disorder are rare, with a prevalence reported to range from 0.002% to 0.014%. Studies have shown that mastectomy yields significant improvements in body image and self-esteem in female-to-male transsexual patients. In patients with grade III breast ptosis, mastectomy with a nipple-areolar complex (NAC) graft is the most commonly used technique, although it has several disadvantages. In the case described herein, a bilateral mastectomy preserving the NAC in an inferior pedicle was performed. Additionally, a thin superior thoracic dermal-fat flap was preserved and eventually sutured at the previous inframammary fold, preventing an inverted T scar. This case shows the advantage of this technique for preserving the blood supply and innervation of the NAC, with a low hypopigmentation risk. Furthermore, in this technique, the patch effect does not impair the results of the NAC graft, and there is no need to use an inverted T scar that may result in thoracic feminization.

Masculinization in juvenile longtooth grouper, $Epinephelus$ $bruneus$, with aromatase inhibitor: changes in GtH subunit mRNA expression and steroids hormone levels

  • Hur, Sung-Pyo;Lim, Bong-Soo;Hwang, In-Joon;Kim, Se-Jae;Ryu, Yong-Woon;Hur, Sang-Woo;Song, Young-Bo;Jeong, Hyung-Bok;Baek, Hae-Ja;Takemura, Akihiro;Lee, Young-Don
    • Animal cells and systems
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    • v.16 no.2
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    • pp.127-134
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    • 2012
  • We investigated the effects of fadrozol, an aromatase inhibitor (AI), and $17{\alpha}$-methyltestosterone (MT) on the induction of sex change in juvenile longtooth grouper $Epinephelus$ $bruneus$, via histological observation of gonads. Changes in the mRNA expression of GtH subunits (FSH-${\beta}$ and LH-${\beta}$) in the pituitary, and estradiol-$17{\beta}$ (E2) and 11-ketotestosterone (11-KT) levels in the blood were also surveyed after AI and MT treatment. Juvenile longtooth groupers ($113{\pm}17g\;body\;weight$; $16.2{\pm}1.2cm\;body\;length$) received intramuscular injections of AI at 3 (3-AI) and 5 (5-AI) mg/kg BWdoses and MT at a 5 mg/kg BW (5-MT) dose. At week 7 post-injection, 3-AI and 5-MT oocytes were degenerated, and gonads of the 5-AI group initiated spermatogenesis. At week 21 post-injection, 3-AI- and 5-MT-treated gonads contained spermatogonia and spermatocytes, while 5-AI treatment induced advanced stages of spermatogenesis. The serum E2 level showed no significant differences throughout the experimental period, whereas that of 11-KT was significantly elevated in the 5-AI group at weeks 7 and 21 post-injection. A significant increase in the expression of FSH-${\beta}$ mRNA was evident in the 5-AI group at week 21 post-injection. In contrast, LH-${\beta}$ mRNA expression did not significantly differ among groups during the experimental period. These results imply that sex change has two stages in the longtooth grouper. In the first stage, oocytes are degenerated by the stimulation by 11-KT, and in the second stage spermatogenesis occurs, owing to the co-effects of 11-KT and FSH-${\beta}$.

Induction of Intersex and Masculinization of the Equilateral Venus, Gomphina veneriformis (Bivalvia: Veneridae) by Zinc

  • Ju, Sun-Mi;Park, Jung-Jun;Lee, Jung-Sick
    • Animal cells and systems
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    • v.13 no.3
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    • pp.339-344
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    • 2009
  • This study aims to find out the effect of heavy metals, as is the case of EDCs (endocrine disrupting chemicals), on reproductive endocrine disruption of aquatic animals. In the present experiment zinc, which is a heavy metal well known for its androgenous activity, was used. The experimental period was 24 weeks, starting in November during the inactive stage of the clam's reproductive cycle. The experimental groups were composed of one control condition and three zinc exposure conditions (0.64, 1.07, and 1.79 mg/L). The sex ratio (F:M) was 1:1.06 in the control group and 1:1.70 in all the exposed group, illustrating the tendency for higher proportion of males with increases in zinc concentration. Gonad maturity was higher in 1.07, and 1.79 mg/L groups compared to the control group, with higher maturity observed in males than females. Intersex individuals made up 24.7% of the exposed group, while females exhibited a higher ratio than the males with increasing zinc concentration. The results of this study indicate that zinc functions as an androgenic effector on the reproduction of Gomphina veneriformis.

A Study on the Feminism through Contemporary Fashion (현대복식에 표현된 페미니즘에 관한 연구)

  • 장영주;김명숙
    • Korean Journal of Human Ecology
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    • v.2 no.2
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    • pp.63-79
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    • 1999
  • The essence of Feminism is to establish the women's subjecthood as representing women's sexual characteristic and emerging from the fixed idea about women in our androcentric society. Feminism has been developed in various stages : the homogeneous theory which emphasized the similarity between men and women, the heterogeneous theory which persisted in he difference between men and women and underscored womanhood as an unique quality, androgynous theory which insisted on the common of two sexes since 1980's. The purpose of the thesis is to discuss the correlation between the feminism and the fashion, to examine its influence on shaping the contemporary fashion, and to infer what the women's fashion be like in the coming 21st century. The result of the thesis is as follows : First, the Mannish Look had been developed from the masculinization of female clothing by borrowing the style of women from that of men clothes since 1970's. Second, the Glamor Look has been stressed as the feminism began to swing toward which emphasized the difference between men and women, and women's sexual characteristics from the late 1970's. Third, from the late 19th century, the Fetish Look is still employed in various ways by the avant-garde designers, which impowered to increase the visualization of sex. Fourth, the Androgynous Look was born, androgynous image and neutral image, by the influence of the socio-cultural aspect of gender rather than the physical aspect from the middle 1980's.

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Comparison of Socio-cultural Meaning on the Power Suit Expressed in American and Korean Feminism Films (미국과 한국 페미니즘 영화에 나타난 파워 수트의 사회문화적 의미 비교)

  • Yoon, Jin-Young;Yim, Eun-Hyuk
    • Journal of the Korean Society of Clothing and Textiles
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    • v.36 no.9
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    • pp.916-927
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    • 2012
  • In the $21^{st}$ century, woman leaders are able to influence society through improved social status and economic power. From 1980-1990 there was a rapid global social development of feminism and improved media perceptions. The progression of this process is reflected by female characters in feminism films that included a new dress style. The power suit emerged in the U.S.A of the 1980s, as a dress code that showed the workplace uniform of a professional woman and spread to Korea as an influential style. This study defines the different and similar aspects in the development of women's position and the role involved in a structural background through a comparison of the socio-cultural meaning of the power suit expressed in American and Korean feminism films. For analysis, this study chose American films in the 1980s and Korean films in 1990s that fulfilled elements about feminism films. Subsequently in American feminism films, the power suit expressed an equal authority with men, strategic use of femininity according to task type, and a dissipation of symbolic effects like a rich look. In Korean feminism films, the power suit expressed an end of femininity like female transvestite, independent female images with the masculinization of appearance, and a mix of new and traditional styles.