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Anesthetic efficacy of supplemental buccal infiltration versus intraligamentary injection in mandibular first and second molars with irreversible pulpitis: a prospective randomized clinical trial

  • Zargar, Nazanin;Shojaeian, Shiva;Vatankhah, Mohammadreza;Heidaryan, Shirin;Ashraf, Hengameh;Baghban, Alireza Akbarzadeh;Dianat, Omid
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.22 no.5
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    • pp.339-348
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    • 2022
  • Background: To compare the anesthetic efficacy of supplemental buccal infiltration (BI) (1.7 ml) versus intraligamentary (IL) injection containing 0.4 ml of 4% articaine with 1:100.000 epinephrine after an inferior alveolar nerve block (IANB) with 1.7 ml 2% lidocaine in the first and second mandibular molars diagnosed with irreversible pulpitis (IP). Methods: One hundred subjects diagnosed with IP of either the mandibular first (n = 50) or second molars (n = 50) and failed profound anesthesia following an IANB were selected. They randomly received either the IL or BI techniques of anesthesia. Pain scores on a 170 mm Heft-Parker visual analog scale were recorded initially, before, and during supplemental injections. Furthermore, pulse rate was measured before and after each supplemental injection. During the access cavity preparation and initial filing, no or mild pain was assumed to indicate anesthetic success. The chi-square test, Mann-Whitney U test, and independent samples t-test were used for the analyses. Results: The overall success rates were 80% in the IL group and 74% in the BI group, with no significant difference (P = 0.63). In the first molars, there was no significant difference between the two techniques (P = 0.088). In the second molars, IL injection resulted in a significantly higher success rate (P = 0.017) than BI. IL injection was statistically more successful (P = 0.034) in the second molars (92%) than in the first molars (68%). However, BI was significantly more successful (P = 0.047) in the first molars (88%) than in the second molars (64%). The mean pulse rate increase was significantly higher in the IL group than in the BI group (P < 0.001). Conclusions: Both the IL and BI techniques were advantageous when used as supplemental injections. However, more favorable outcomes were observed when the second molars received IL injection and the first molars received BI.

Anti-inflammatory and Anti-oxidant Activities of Aster Scaber Ethanol Extract

  • Saba, Evelyn;Je, Nayeong;Song, Ji Eun;Shi, Sangwoo;Lee, Juho;Jung, Oneyoung;Han, Beom Jun;Lee, Soo Young;Park, Jongwon;Lee, Yuan Yee;Rhee, Man Hee
    • Biomedical Science Letters
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    • v.28 no.3
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    • pp.170-177
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    • 2022
  • In mountainous regions, wild herbs which can also be edible in nature for humans and animals possess a wide array of biologically diversified properties. It is because of the fact that due to the cold weather of mountains; they are enriched in certain kinds of phytochemicals such as anti-oxidants, anti-inflammatory and many more. One such kind of an herb is Aster scaber (AS) in Korean. It is a widely cultivated culinary herb in Korean peninsula and used as a side dish in Korean culinary cuisine. In view of its extensive use in cuisine, we geared to unravel the anti-oxidant and anti-inflammatory effects of AS in murine alveolar macrophage cell line (MH-S). 2,2'-Azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) and 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) assays revealed a dose dependent (7.8~1,000 ㎍/mL) inhibition of oxidation by AS 70% ethanol (ASE) extract as compared to Trolox and Ascorbic acid respectively. Nitric oxide assay (NO) showed a dose dependent decrease (5~40 ㎍/mL) in MH-S cells with ASE when stimulated with Coal Fly Ash (CFA). Moreover, this dose for NO reduction was also found to be least cytotoxic for cells as determined by cellular viability (MTT) assay. The gene expression of pro-inflammatory mediators (iNOS and COX-2) and cytokines (IL-6 and IL-1β) and were also dose dependently inhibited by ASE in MH-S cells through RT-PCR. Therefore, in light of these findings, AS exhibited a strong anti-oxidant and anti-inflammatory agent. These results also justify the extensive use of this mountainous herb in culinary practices for beneficial effects on human health.

Opening New Horizons with the L4 Mission: Vision and Plan

  • Kyung-Suk Cho;Junga Hwang;Jeong-Yeol Han;Seong-Hwan Choi;Sung-Hong Park;Eun-Kyung Lim;Rok-Soon Kim;Jungjoon Seough;Jong-Dae Sohn;Donguk Song;Jae-Young Kwak;Yukinaga Miyashita;Ji-Hye Baek;Jaejin Lee;Jinsung Lee;Kwangsun Ryu;Jongho Seon;Ho Jin;Sung-Jun Ye;Yong-Jae, Moon;Dae-Young Lee;Peter H. Yoon;Thiem Hoang;Veerle Sterken;Bhuwan Joshi;Chang-Han Lee;Jongjin Jang;Jae-Hwee Doh;Hwayeong Kim;Hyeon-Jeong Park;Natchimuthuk Gopalswamy;Talaat Elsayed;John Lee
    • Journal of The Korean Astronomical Society
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    • v.56 no.2
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    • pp.263-275
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    • 2023
  • The Sun-Earth Lagrange point L4 is considered as one of the unique places where the solar activity and heliospheric environment can be observed in a continuous and comprehensive manner. The L4 mission affords a clear and wide-angle view of the Sun-Earth line for the study of the Sun-Earth and Sun-Moon connections from he perspective of remote-sensing observations. In-situ measurements of the solar radiation, solar wind, and heliospheric magnetic field are critical components necessary for monitoring and forecasting the radiation environment as it relates to the issue of safe human exploration of the Moon and Mars. A dust detector on the ram side of the spacecraft allows for an unprecedented detection of local dust and its interactions with the heliosphere. The purpose of the present paper is to emphasize the importance of L4 observations as well as to outline a strategy for the planned L4 mission with remote and in-situ payloads onboard a Korean spacecraft. It is expected that the Korean L4 mission can significantly contribute to improving the space weather forecasting capability by enhancing the understanding of heliosphere through comprehensive and coordinated observations of the heliosphere at multi-points with other existing or planned L1 and L5 missions.

Prognostic Value of Coronary CT Angiography for Predicting Poor Cardiac Outcome in Stroke Patients without Known Cardiac Disease or Chest Pain: The Assessment of Coronary Artery Disease in Stroke Patients Study

  • Sung Hyun Yoon;Eunhee Kim;Yongho Jeon;Sang Yoon Yi;Hee-Joon Bae;Ik-Kyung Jang;Joo Myung Lee;Seung Min Yoo;Charles S. White;Eun Ju Chun
    • Korean Journal of Radiology
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    • v.21 no.9
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    • pp.1055-1064
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    • 2020
  • Objective: To assess the incremental prognostic value of coronary computed tomography angiography (CCTA) in comparison to a clinical risk model (Framingham risk score, FRS) and coronary artery calcium score (CACS) for future cardiac events in ischemic stroke patients without chest pain. Materials and Methods: This retrospective study included 1418 patients with acute stroke who had no previous cardiac disease and underwent CCTA, including CACS. Stenosis degree and plaque types (high-risk, non-calcified, mixed, or calcified plaques) were assessed as CCTA variables. High-risk plaque was defined when at least two of the following characteristics were observed: low-density plaque, positive remodeling, spotty calcification, or napkin-ring sign. We compared the incremental prognostic value of CCTA for major adverse cardiovascular events (MACE) over CACS and FRS. Results: The prevalence of any plaque and obstructive coronary artery disease (CAD) (stenosis ≥ 50%) were 70.7% and 30.2%, respectively. During the median follow-up period of 48 months, 108 patients (7.6%) experienced MACE. Increasing FRS, CACS, and stenosis degree were positively associated with MACE (all p < 0.05). Patients with high-risk plaque type showed the highest incidence of MACE, followed by non-calcified, mixed, and calcified plaque, respectively (log-rank p < 0.001). Among the prediction models for MACE, adding stenosis degree to FRS showed better discrimination and risk reclassification compared to FRS or the FRS + CACS model (all p < 0.05). Furthermore, incorporating plaque type in the prediction model significantly improved reclassification (integrated discrimination improvement, 0.08; p = 0.023) and showed the highest discrimination index (C-statistics, 0.85). However, the addition of CACS on CCTA with FRS did not add to the prediction ability for MACE (p > 0.05). Conclusion: Assessment of stenosis degree and plaque type using CCTA provided additional prognostic value over CACS and FRS to risk stratify stroke patients without prior history of CAD better.

Analysis of Microbiological Contamination in Cultivation and Distribution Stage of Melon

  • Park, Kyeong-Hun;Yun, Hye-Jeong;Kim, Won-Il;Kang, Jun-Won;Millner, Patricia D.;Micallef, Shirley A.;Kim, Byeong-Seok
    • Korean Journal of Soil Science and Fertilizer
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    • v.46 no.6
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    • pp.615-622
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    • 2013
  • The purpose of this study was to evaluate microbial contamination of melons in Korea. A total of 123 samples including melon fruits, leaves, seeds, soils, and irrigation water were collected from farms and markets to detect total aerobic bacteria, coliform, Escherichia coli, and pathogenic bacteria such as Bacillus cereus, Listeria monocytogenes, Salmonella spp., and Staphylococcus aureus. Samples were collected from Iksan and Nonsan farms to monitor bacterial levels on pre-market melons. The total aerobic and coliform bacteria on melon cultivation were between 0.43 and 6.65 log CFU $g^{-1}$, and 0.67 and 2.91 log CFU $g^{-1}$, respectively. Bacillus cereus, a fecal coliform, was detected in soils and melon leaves from Iksan farm at 2.95, 0.73 log CFU $g^{-1}$, respectively, and in soils from Nonsan farm at 3.16 log CFU $g^{-1}$. Market melon samples were collected to assay bacterial load on melon being sold to consumers. The contamination levels of total aerobic bacteria in agricultural markets, big-box retailers, and traditional markets were 4.82, 3.94, 3.99 log CFU $g^{-1}$, respectively. The numbers of coliform in melon on the markets ranged from 0.09 to 0.49 log CFU $g^{-1}$. Listeria monocytogenes, Salmonella spp., and Staphylococcus aureus were not detected in any samples. The count of total aerobic bacteria on melon seeds ranged from 0.33 to 3.34 log CFU $g^{-1}$. This study found that irrigation water, soil, manure and various farm work activities including post-harvest processes were latent sources of microbial contamination. These results suggest that hygienic management and monitoring of soil, water, and agricultural material should be performed to reduce microbial contamination in melon production.

Comparison of Work Values of Undergraduate-level Foodservice Major Students (외식.급식경영 전공 학생들의 근로 가치관 비교)

  • Yoon, Ji-Young
    • Journal of the East Asian Society of Dietary Life
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    • v.21 no.1
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    • pp.134-145
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    • 2011
  • The purpose of this study was to examine the work values of undergraduate-level foodservice major students. In order to assess work values of the participating students, this study adopted 'Maryland Work Values Inventory'. Data from a total of 290 surveys were collected. The participants consisted of 146 commercial foodservice major students and 144 institutional foodservice major students. Among the seven work values, both groups ranked 'job advancement' as the most important work value. Commercial foodservice major students rated 'altruism' as the least important work value, whereas it was 'stimulation' for institutional foodservice major students. 'Need for work' was evaluated statistically higher by junior and senior students compared to sophomore students of commercial foodservice major (p<0.05). In both foodservice majors, a positive relationship was found between work value scores and grade levels. All work value scores tended to be higher for students in higher grades. This tendency was especially statistically clear for the value 'need for work' for commercial foodservice major students and 'money and prestige' for institutional foodservice major students (p<0.05). There were some gaps in the work values between students with different career field choices. For the commercial foodservice majors, those interested in fine dining perceived 'satisfaction and accomplishment' and 'altruism' as more important [4.33 (p<0.05) and 4.05 (p<0.01), respectively] compared to students who had interests in fast food restaurants (4.06 and 3.67 respectively). Scores for 'satisfaction & accomplishment' (p<0.05), 'money & prestige' (p<0.001), and 'stimulation' (p<0.001) were significantly different among institutional foodservice major students. In addition, students more interested in industrial foodservice field regarded 'money & prestige' and 'stimulation' as less important as indicated by noticeably lower scores (3.74, 3.55 respectively) in comparison to the other group (p<0.001). The results of this study, which explored foodservice major students' work values, suggest that there is an increased need for the students to build up their work values as well as for the foodservice industry to offer appropriate work values to future foodservice employees.

The Visitors Characteristics of Urban Ecological Park - The Cases of Gildong Ecological Park, Yeouido Tributary Ecological Park - (도시 생태공원 이용자 특성 연구 - 길동생태공원, 여의도샛강생태공원을 사례로 -)

  • Kim, Eun-Young;Lee, Jung-A;Kim, Hyoung-Gon;Chon, Jin-Hyung
    • Journal of the Korean Institute of Landscape Architecture
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    • v.42 no.1
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    • pp.64-74
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    • 2014
  • Ecological parks enable the sustainable use of natural resources and can be used as a place for site based environmental education. This study presented an opportunity to expand the scope of user perceptions and leisure benefits into urban ecological parks. However, in-depth studies which are aimed at eco-park visitors seeking the leisure benefits of the eco experience programs are lacking. The primary purpose of this study was to examine the urban ecological park user' characteristics which were derived by analyzing the leisure benefits and attitudes for the environment. Also, the attitudes about the environment, and the leisure benefits of visiting urban ecological parks was found to influence visitors' overall satisfaction. To accomplish the purposes of this study, a questionnaire survey with 282 samples was carried out on the urban ecological park(Gildong ecological park, Yeouido tributary ecology park). The results of the analyses are as following: urban ecological park visitors had a positive attitude about the environment, and felt satisfied by the visitors' leisure benefits. The study also examined the relationships between visitors' expectations of the leisure benefits both before visiting and after visiting. The results showed that ecological park visitors had greater expectations regarding the leisure benefits of the ecological program. Leisure benefits have a positive influence on overall satisfaction, and a positive attitude for the environment does not affect satisfaction. This study reaches the conclusion that the ecology experience program utilizing ecological parks is very effective with regard to overall satisfaction in urban areas toward the general environment and ecological parks. One of the major implications of this study is to offer a way to improve user leisure benefits and promote ecological programs by developing ecological parks for the future.

Quantification of Odorants from Animal Husbandry using Solid-phase Microextraction (고상(固相) 미세 추출법에 의한 축산 관리시설에서 발생하는 악취성 가스 화합물의 정량적 평가)

  • Kim, Jae-Hyuck;Choi, Hong-Lim;Kown, So-Young;Lim, Hong-Lae;McConnell, Laura L.;Arispe, Susana;Park, Chul-Hwi;Kim, Hyun-Ook
    • Journal of Korean Society of Environmental Engineers
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    • v.28 no.2
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    • pp.158-164
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    • 2006
  • Offensive odor from CAFO(concentrated animal feeding operation) and its control have become a significant issue in Korea. Control of odors from the CAFO requires to identify major odorant and their generation mechanisms. In this study, an easy method to collect gas sample and to quantify its odorants is proposed. The method involves on-site odorant extraction with solid-phase microextraction and quantitation with GC/MSD or GC/FID. Analytes of the current study include: trimethylamine(TMA), carbon disulfide($CS_2$), dimethyl sulfide(DMS), dimethyl disulfide(DMDS), acetic acid(AA), propionic acid(PA) and n-butyric acid(BA). The resulting linearity($R^2$) of calibration curve for each analyte was good over the range from several ppbv to ppmv; 0.984 for TMA(0.056-1.437), 0.996 for $CS_2$(0.039-0.999), 0.994 for DMS(0.029-0.756), 0.995 for DMDS(0.024-0.623), 0.992 for AA(0.068-1.314), 0.955 for PA(0.047-0.940), and 0.976 for BA(0.036-0.712). Method detection limits were 5.67, 6.39, 5.78, 25.2, 0.098, 0.363 and 0.099 ppbv for AA, PA, BA, TMA, DMS, $CS_2$, and DMDS, respectively. With the developed method, odorants from poultry, swine, and cattle barns were analysed. All the compounds but DMDS were detected from the sample collected in the poultry barn, and their levels exceeded the representative published human olfactory threshold.

Clinical Implementation of an Eye Fixing and Monitoring System with Head Mount Display (Head Mount Display (HMD)를 이용한 안구의 고정 및 감시장치의 임상사용 가능성 확인)

  • Ko, Young-Eun;Park, Seoung-HO;Yi, Byong-Yong;Ahn, Seung-Do;Lim, Sang-Wook;Lee, Sang-Wook;Shin, Seong-Soo;Kim, Jong-Hoon;Choi, Eun-Kyung;Noh, Young-Ju
    • Progress in Medical Physics
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    • v.18 no.1
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    • pp.1-6
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    • 2007
  • A system to non-invasively fix and monitor eye by a head mounted display (HMD) with a CCD camera for stereotactic radiotherapy (SRS) of uveal melanoma has been developed and implemented clinically. The eye fixing and monitoring system consists of a HMD showing patient a screen for fixing eyeball, a CCD camera monitoring patient's eyeball, and an immobilization mask. At flrst, patient's head was immobilized with a mask. Then, patient was Instructed to wear HMD, to which CCD camera was attached, on the mask and see the given reference point on its screen. While patient stared at the given point in order to fix eyeball, the camera monitored Its motion. Four volunteers and one patient of uveal melanoma for SRS came into this study. For the volunteers, setup errors and the motion of eyeball were analyzed. For the patient, CT scans were peformed, with patient's wearing HMD and fixing the eye to the given point. To treat patient under the same condition, daily CT scans were also peformed before every treatment and the motion of lens was compared to the planning CT Setup errors for four volunteers were within 1mm and the motion of eyeball was fixed within the clinically acceptable ranges. For the patient with uveal melanoma, the motion of lens was fixed within 2mm from daily CT scans. An eye fixing and monitoring system allowed Immobilizing patient as well as monitoring eyeball and was successfully implemented in the treatment of uveal melanoma for SRS.

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Effects of the Field Management Training Program for Home Care Services : Understanding and Professional Competence (현장관리중심 교육훈련프로그램의 방문건강관리 이해도 및 업무수행능력 인식에 대한 효과)

  • Kim, Jae-Hee
    • Journal of agricultural medicine and community health
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    • v.35 no.2
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    • pp.111-123
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    • 2010
  • Objectives: The purpose of the present study is to examine the effects of the Field Management Training Program for home care services personnel on their understanding and professional competences. Methods: The subjects were 373 team managers of public home care services who participated in the training program. Data was collected with a self-administered questionnaire in April and September, 2007. The subjects' level of understanding of home care was measured by 35 questions divided into 8 categories while their professional competence was measured by 15 questions divided into 5 categories. Result: After attending the training, the subjects' understanding improved from 20.90 points (possible range: 4~32) to 26.11 points. The most improvement was evident in the Planning and Public Health Education categories. Their professional competences improved from 10.81 points (possible range: 4~16) to 12.51 points. The improvement of their understanding and professional competences differed across to training places. It was also evident that an increase in understanding brought about an increase in professional competence. Conclusion: The Field Management Training Program needs to be continued with efforts to reduce the differences of training effects between training places. And additional recommendations should be made through further evaluation of subsequent training programs.