• Biomolecules & Therapeutics
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• v.23 no.2
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• pp.110-118
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• 2015

According to the expansion of lifespan, neuronal disorder based on inflammation has been social problem. Therefore, we isolated shikonin from Lithospermum erythrorhizon and evaluated anti-inflammatory effects of shikonin in lipopolysaccharide (LSP)-stimulated BV2 microglial cells. Shikonin dose-dependently inhibits the expression of the proinflammatory mediators, nitric oxide (NO), prostaglandin $E_2$ ($PGE_2$), and tumor necrosis factor-${\kappa}B$ (TNF-${\alpha}$) as well as their main regulatory genes and products such as inducible NO synthase (iNOS), cyclooxygenase-2 (COX-2), and TNF-${\alpha}$ in LPS-stimulated BV2 microglial cells. Additionally, shikonin suppressed the LPS-induced DNA-binding activity of nuclear factor-${\kappa}B$ (NF-${\kappa}B$) to regulate the key regulatory genes of the proinflammatory mediators, such as iNOS, COX-2, and TNF-${\alpha}$, accompanied with downregulation of reactive oxygen species (ROS) generation. The results indicate that shikonin may downregulate the expression of proinflammatory genes involved in the synthesis of NO, $PGE_2$, and TNF-${\alpha}$ in LPS-treated BV2 microglial cells by suppressing ROS and NF-${\kappa}B$. Taken together, our results revealed that shikonin exerts downregulation of proinflammatory mediators by interference the ROS and NF-${\kappa}B$ signaling pathway.

• Journal of the Korean Society of Safety
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• v.17 no.1
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• pp.11-17
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• 2002

The purpose of this study was to present the method to choose the optimization machining condition for the wire electric machine. This was completed by examining the ever-changing quality of the material and by improving the function of the wire electric discharge machine. Precision metal mold products and the unmanned wire electric discharge machining system were used and then applied in industrial fields. This experiment uses the wire electric discharge machine with brass wire electrode of 0.25mm. To measure the precision of the machining surface, average values are obtained from 3 samples of measures of center-line average roughness by using a third dimension gauge and a stylus surface roughness gauge. In this experiment, we changed no-node voltage to 7 and 9, pulse-on-time to $6{\mu}s,\;8{\mu}s$ and $10{\mu}s$, pulse-off-time to $8{\mu}s,\;10{\mu}s$ and $13{\mu}s$, and experimented on wire tension at room temperature by 1000gf, 1200gf, and 1400gf, respectively.

• Journal of Advanced Marine Engineering and Technology
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• v.35 no.1
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• pp.102-107
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• 2011

LED-based lighting motivated by significant energy savings provides an opportunistic development of widespread free-space optical communications. Their transceivers have a variety of competitive advantages over RF including high bandwidth density, reliability, lower energy consumption, and long lifetime. But, it is difficult for existing buildings and structures such as ships and vehicles to install the communication cable to the ceiling. In this paper, controller area network (CAN)-based LED lighting communication systems were proposed. Results indicate the viability of developing inexpensive CAN interface modules and transceivers might be embedded in lighting products to support the indoor wireless networking.

• Journal of Fisheries and Marine Sciences Education
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• v.21 no.2
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• pp.291-305
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• 2009

As you known well, Ulsan port is very famous for handling chemical products which occupies about 80% of quantities of all Korean ports. Many ship's operators prefer to handle liquid cargo es at proper anchorages instead of the berth for saving port expenses. Ulsan M-10 anchorage was assigned for handling liquid cargoes, however this anchorage's space is restricted by the oil pipeline which lays under seabed about 400m off from the center of M-10 anchorage, for which we have to consider of the external force and counter force for keeping the safety of anchoring. Where, external force is induced by wind, tidal currents and wave while counter force is induced by holding power of anchor/chain. In this study, author evaluated a method to analyze theoretically the limit of external force condition up to which an anchoring ship can keep her position without dragging, and for which applied to many kinds of combined Ships as mother ship of 50,000 DWT Tanker and 4 sizes of Tanker as alongsided ship.

• Proceedings of the KSRS Conference
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• v.1
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• pp.56-59
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• 2006

In this paper, Korea's first geostationary Communication, Ocean and Meteorological Satellte(COMS) program is introduced. COMS program is one of the Korea National Space Programs to develop and operate a pure civilian satellite of practical-use for the compound missions of meteorological observation and ocean monitoring, and space test of experimentally developed communication payload on the geostationary orbit. The target launch of COMS is scheduled at the end of 2008. COMS program is international cooperation program between KARI and ASTRIUM SAS and funded by Korean Government. COMS satellite is a hybrid satellite in the geostationary orbit, which accommodates multiple payloads of MI(Meteorological Imager), GOCI(Geostationary Ocean Color Imager), and the Ka band Satellite Communication Payload into a single spacecraft platform. The MI mission is to continuously extract meteorological products with high resolution and multi-spectral imager, to detect special weather such as storm, flood, yellow sand, and to extract data on long-term change of sea surface temperature and cloud. The GOCI mission aims at monitoring of marine environments around Korean peninsula, production of fishery information (Chlorophyll, etc.), and monitoring of long-term/short-term change of marine ecosystem. The goals of the Ka band satellite communication mission are to in-orbit verify the performances of advanced communication technologies and to experiment wide-band multi-media communication service mandatory.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.1 no.1
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• pp.3-12
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• 1997

In this study, in Tongyeong area the distribution of marine products that were produced and treated through fishing and cultivating industry and the trend of main fisheries were investigated for fisheries distribution system and fisheries official circles, and then a structural model of fisheries distribution system for direct transaction was suggested under internet environment, which is an important scheme offering a necessary information rapidly and practically to both producers and consumers. Database system was structured according to distributed process. An op-elative scheme were suggested for sewers of local area information center, complementing functions to exceed each server's ability.

• Journal of Advanced Marine Engineering and Technology
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• v.34 no.6
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• pp.852-857
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• 2010

In this paper, we proposed and demonstrated an indoor visible-light communication system using an array of light-emitting diodes (LEDs). The main idea is based on that the LEDs can be used not only for lighting but also for free-space optical communications. Because LEDs offer advantageous properties such as high brightness, reliability, lower power consumption and long lifetime, the indoor visible-light communication systems are going to provide high quality of service by the high radiation power of the LED lighting. Prototype of simplex channel for audio and the full-duplex channel for text message were developed. Results indicates the viability of creating inexpensive free-space optical communication transceivers that might be embedded in commercial light products to supports indoor wireless networking.

• Journal of Advanced Marine Engineering and Technology
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• v.6 no.2
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• pp.21-41
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• 1982

Viscosity, especially characteristic among various properties of visco-elastic fluids such as high polymer solutions, is affected mainly by temperature and concentration. Hence, it is important for fluid engineering to express, by some equations, how the fluid characteristics vary with the change of temperature and concentration and to analyze them to obtain consistent viscous characteristics. High polymer solutions, synthetic products of modern chemical industry, suggest many interesting investigations because they are typical visco-elastic materials. Experimentation was made to derive some useful fluid characteristic equations of SEPARAN-NP10 (polyacylamide) expressed by n (flow behavior index) and K' (consistency index) when it is given temperature and concentration variation. To measure viscosity, capillary viscometer was adopted and the range of experimentation is 0-2,000 P.P.M. in concentration and 15-55 .deg.C in temperature. The experimental results are summarized as follows: The flow behavior index n 1) has nearly constant results irrespective of temperature variation at same conentration and the results are shown in (Table. 4-4-3) 2) has following equation, regardless of temperature, for the variation of concentration. n=-1.0765*10$^{-4}$ P+0.9915 (P:P.P.M.) The consistency index K' 1) has different results for the variation of temperature at same concentration and the results are given in (Table.4-7-2) 2) has following equation for the variation of concentration at same temperature. log 10$^{4}$K' =6.4785*10$^{-4}$ P-1.0529 (P:P.P.M)

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.3A
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• pp.279-286
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• 2010

Although seaman has made a contribution marine transportation and the marine products industry, the current status of preventing occupational disease by monitoring health danger factors is very unsatisfied. Therefore, a monitoring system regarding health condition and disease occurrence of seaman is required. In this paper, we propose a real-time sailor management system based on uniqutious healthcare, which collects various organic signals and analyzes their relation in order to confirm blood pressure, temperature and pulsation of seaman. The proposed system enables a medical doctor to manage the diseases anywhere at any time even via a PC and PDA.

• Fisheries and Aquatic Sciences
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• v.22 no.11
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• pp.24.1-24.7
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• 2019

Sporophylls from sea mustard, Undaria pinnatifida, which are by-products in seaweed production industries, were taken from Hansan Island, Tongyeong, and Gijang, Busan, and investigated for their fucoidan content and corresponding antioxidant activities. The extracted fucoidan yield from sporophylls of sea mustard samples from Tongyeong (TF) and Gijang (GF) were 12.1% and 13.6%, respectively. The antioxidant activities assessment of TF and GF extracts showed relative significant difference between samples, suggesting effect of location on bioactivities of fucoidan samples. GF was 50-68% more effective than TF against DPPH and superoxide radicals samples which may be attributed to the difference in their degree of sulfation and monosaccharide composition. Meanwhile, TF exhibited greater scavenging activity against hydroxyl radicals compared to GF which could be due to protein impurities.