• 대한토목학회논문집
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• 제36권5호
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• pp.867-879
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• 2016

1970년대 이후 지속적인 차량의 증가로 배기가스에 의한 환경오염과 보행자 중심의 고유영역이 점차 축소되어 가고 있고, 중심상업지역, 학교 주변의 통학로, 차량이 통행하지 않은 산책로, 골목길 등 불특정 다수가 통행하는 장소에 대한 체계적 관리나 보행자 안전을 위한 최소한의 시설 구축이 미흡한 실정이다. 최근 "보행안전 및 편의 증진에 관한 법률"이 시행됨에 따라 행정자치부를 중심으로 차없는 거리에 관한 연구가 활발히 진행되고 있으나, 그에 따른 평가가중치의 산정기준은 미흡한 실정이며, 지자체를 통해 자체적으로 이루어지고 있는 차없는 거리 사업추진에 대한 평가는 이용객의 목적 및 규모, 체류시간 등을 통해 정성적인 평가만 이루어지고 있는 것이 현실이다. 본 연구에서는 차없는 거리 선정방법을 제시함으로써 앞으로 조성될 차없는 거리에 대한 선정방법 정립에 목적을 두고 설문조사를 통하여 연구를 수행하였다. 설문조사는 차없는 거리의 유형별 평가지표를 토대로 차없는 거리의 평가를 위한 가중치 제시를 목적으로 도시 통공학과 학사 이상, 교수, 공무원, 엔지니어링 회사 종사자 총 200명을 대상으로 차없는 거리의 평가가중치 제시 및 평가지표 선정을 위한 전문가 설문조사(F.G.I)를 실시하였다. 차없는 거리의 유형별 평가목표와 목표별 항목을 분류하여 가중치를 부여하고, 각 항목에 따른 세부지표별 가중치 제시를 통해 그 결과값을 점수화하였다. 본 연구에서 도출된 차없는 거리 유형별 평가가중치는 차없는 거리 조성을 위한 선정기준 수립방법의 일환으로, 향후 차없는 거리 평가방법 및 선정 기준 수립시 충분한 기여를 할 수 있을 것으로 판단된다.

• 한국응용곤충학회지
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• 제48권2호
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• pp.237-243
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• 2009

양배추 유묘에서 도둑나방 유충의 경제적 피해허용수준과 요방제 수준을 설정하기 위하여 도둑나방 유충 접종 밀도에 따른 양배추의 생육, 피해 및 수량을 조사하였다. 포장실험에서 파종 40일 양배추 유묘에 주당 0, 1, 4, 8, 16마리의 도둑나방 2령 유충들을 접종하고 30일 후 수량조사결과 처리 간 사이가 없었고, 양배추는 도둑나방 가해에 대하여 보상적 반응을 보였다. 반면, 유리온실 실험에서 정식 25일 양배추 유묘에 주당 0, 2, 5, 8, 12마리의 도둑나방 2령 유충들을 접종한 결과 15일 후 양배추의 평균생체중은 무처리에서 38.3g, 2마리 접종구에서 36.7g, 5마리 접종구에서 21.7g, 8마리 접종구에서 23.3g, 12마리 접종구에서 16.7g으로 도둑나방 유충의 접종수가 증가할수록 양배추의 생체중은 유의하게 줄어들었다. 도둑나방 유충 발생과 수량손실과의 관계를 구명하기 위하여 누적발생일수(cumulative insect days)와 양배추 유묘의 손실률(%)과의 관계를 회귀분석한 결과 비선형식인 logistic 모형에 잘 적용되었다. 이 식으로부터 수익한계인(gain threshold) 5%와 양배추 상품화율(91%)을 감안했을 때, 수량 감소율 14%에서 도둑나방 2령 유충의 경제적피해수준은 44 CID 이었다. 또한 요방제 밀도는 경제적 피해수준의 80%가 되는 35 CID로 추정되었다. 본 결과는 양배추 유묘시기에 도둑나방 유충을 방제하기 위한 경제적인 방제적기를 제공함으로써 본 해충의 효율적인 관리에 활용될 수 있을 것으로 판단된다.

• 항공우주정책ㆍ법학회지
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• 제31권2호
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• pp.237-269
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• 2016

Asia-Pacific Space Cooperation Organization (APSCO) is the only intergovernmental space cooperation organization in Asia. Since its establishment to date, eight countries have signed the convention and become member states. South Korea participated actively in the preparatory phase of creating the organization, and one conference organized by AP-MCSTA which is the predecessor of APSCO was held in South Korea. However, after the APSCO Convention was opened for signature in 2005 to date, South Korea does not ratify the Convention and become a member. The rapid development of space commercialization and privatization, as well as the fastest growing commercial space market in Asia, provides opportunities for Asian countries to cooperate with each other in relevant space fields. And to participate in the existing cooperation framework (e.g., the APSCO) by the Asian space countries (e.g., South Korea) could be a proper choice. Even if the essential cooperation in particular space fields is challenging, joint space programs among different Asian countries for dealing with the common events can be initiated at the first steps. Since APSCO has learned the successful legal arrangements from ESA, the legal measures established by its Convention are believed to be qualified to ensure the achievement of benefits of different member states. For example, the regulation of the "fair return" principle confirms that the return of interests from the relevant programs is in proportion to the member's investment in the programs. Moreover, the distinguish of basic and optional activities intends to authorize the freedom of the members to choose programs to participate. And for the voting procedure, the acceptance of the "consensus" by the Council is in favor of protecting the member's interest when making decisions. However, political factors that are potential to block the participation of South Korea in APSCO are difficult to be ignored. A recent event is an announcement of deploying THAAD by South Korea, which causes tension between South Korea and China. The cooperation between these two states in space activities will be influenced. A long-standing barrier is that China acts as a non-member of the main international export control mechanism, i.e., the MTCR. The U.S takes this fact as the main reason to prevent South Korea to cooperate with China in developing space programs. Although the political factors that will block the participation of South Korea in APSCO are not easy to removed shortly, legal measures can be taken to reduce the political influence. More specifically, APSCO is recommended to ensure the achievement of commercial interests of different cooperation programs by regulating precisely the implementation of the "fair return" principle. Furthermore, APSCO is also suggested to contribute to managing the common regional events by sharing satellite data. And it is anticipated that these measures can effectively response the requirements of the rapid development of space commercialization and the increasing common needs of Asia, thereby to provide a platform for the further cooperation. In addition, in order to directly reduce the political influence, two legal measures are necessary to be taken: Firstly, to clarify the rights and responsibilities of the host state (i.e., China) as providing assistance, coordination and services to the management of the Organization to release the worries of the other member states that the host state will control the Organization's activities. And secondly, to illustrate that the cooperation in APSCO is for the non-military purpose (a narrow sense of "peaceful purpose") to reduce the political concerns. Regional cooperation in Asia regarding space affairs is considered to be a general trend in the future, so if the participation of South Korea in APSCO can be finally proved to be feasible, there will be an opportunity to discuss the creation of a comprehensive institutionalized framework for space cooperation in Asia.

• Tuberculosis and Respiratory Diseases
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• 제39권3호
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• pp.219-227
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• 1992

연구배경 : 기관지 천식의 병인에 염증반응이 중요한 역할을 한다고 알려져 있고 염증을 억제하기 위해 스테로이드제제가 치료제로서 가장 많이 사용되고 있다. 흡입용 스테로이드는 전신적 부작용이 적어 경구용 스테로이드보다 비교적 안전하게 사용되고 있으나 효과와 부작용에 대하여는 아직 논란이 많다. 이에 저자들은 기관지 천식환자에서 흡입용 스테로이드인 budesonide의 효과와 전신적 부작용의 지표로서 부신피질-뇌하수체축에 대한 영향을 알고자 본 실험을 했다. 방법 : 강남성모병원에 내원한 기관지 천식환자 23명에서 내원당시, placebo투여 2주후, budesonide투여후 3주와 6주에 임상증상, 폐기능 검사, 히스타민 기도 유발검사, 오전 8시와 오후 4시의 ACTH 및 cortisol을 측정하여 비교하였다. 결과 : 1) 폐기능의 변화 : PEFR, FEV1, FVC가 budesonide 치료 3주일부터 증가하기 시작하여 치료전보다 의미있는 개선효과가 있었다. 2) 증상의 변화 : 호흡곤란 치료후 3주일과 6주일후에 의미있는 증상의 개선이 있었다. 객담 : 치료후 3주일과 6주일에 치료전보다 의미있는 증상의 개선이 있었다. 수포음 : 치료후 3주일과 6주일에 의미있는 차이가 있었다. 3) 히스타민 기도 유발 시험 : 치료 3주일에는 의미있는 차이는 없었으나, 치료 6주일에 의미있는 차이가 있었다(p<0.05). 4) 혈중 Cortisol의 변화 : Budesonide 6주일 치료후에 오전 8시와 4시의 cortisol에는 의미있는 차이가 없었다. 5) 혈중 ACTH의 변화 : Budesonide 6주 치료 전후의 혈중 ACTH에는 영향이 없었다. 결론 : 이상의 결과로 기관지 천식의 치료에 흡입용 스테로이드인 budesonide는 하루 $800{\mu}g$씩 투여할 경우 치료후 3주일부터 유의한 증상의 개선효과가 나타나기 시작하여 6주일후에는 3주일보다 임상증상이 더욱 개선되고, 부신피질-뇌하수체축에는 뚜렷한 억제능이 없는 것으로 사료된다.

• 근관절건강학회지
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• 제5권1호
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• pp.57-71
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• 1998

This study purports to examine sociodemographic characteristics and those factors associated with osteoarthritis in women experiencing the disease in order to make suggestions for the prevention and management of osteoarthritis in women. The subjects were 143 women who were diagnosed to have osteoarthritis and under follow-up care at an outpatient department of a university-affiliated hospital. The data were collected through personal interviews by using the structured questionnaire between October 6 and October 24, 1997. The degree of daily living activities was measured with 24 items, which were made based upon Katz Index, Barthel Index and Functional Status Index. Each item has 4 response categories : (1) being able to do alone with any difficulty, (2) being able to do alone with some difficulty, (3) being able to do alone with the help of a person or an instrument, (4) not being able to do at all. The data was analyzed with correlation analysis, t-test, ANOVA, and regression analysis. The results are summarized as follows : 1. As for the age of the subjects, 59.4% were between 45 and 64 years, while 28% were 65 years and above. The subjects having religion were 71.7% and 44.1% of the subjects were protestants. The educational level was low : 31.5% graduated from elementary school, while 30.1% had no formal education. Those married subjects were 72%. Fifty nine percent of the subjects evaluated their economic status as middle class. 2. Those people from whom the subjects currently receive some help were spouses in 35.8% of the subjects. Likewise, 50% of the subjects indicated spouse as the people from whom they want to receive help. 3. The score of the ability of daily living activities ranged between 48 and 96, with the mean of 78.94. Those means of physical activity, ADL(activities of daily living) and IADL(instrumental activities of daily living) were 14.89, 13.97 and 50.09, respectively. Except for the items of carrying heavy stuff and of washing clothes in the sitting position the subjects showed independence in more than 90% of the items, where Independence is defined as being able to do alone or with the help of a person or an instrument. 4. The increase in age was a significant predictor of the decrease in the ability of daily living activities. Those graduated from middle school and above showed a significantly higher degree in the ability of daily living activities than those with less educational level. The married women revealed significantly higher scores in physical activity, ADL, and IADL than the unmarried ones. The ability of daily living activities was not significantly related to having religion, economic status and living with family. 5. The average duration of experiencing osteoarthritis was 4 years and 7 months. Regarding the site of the onset, 65% of the subjects indicated knees. The women with osteoarthritis for less than 3 years were 65%. The ability of daily living activities was significantly different by the duration of illness : the longer the duration of illness, the less the ability of activities. The above findings suggest the need for developing those programs for prevention disabilities in performing daily living activities and for managing diseases targeting the women of middle and old age, with low educational level, and with unmarried status. In addition, there should be developed an instrument for measuring the ability of daily living activities which reflects daily lives of Korean women with osteoarthritis in order to examine comprehensive effects of osteoarthritis on women's daily lives in this country.

• 경영정보학연구
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• 제18권1호
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• pp.57-78
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• 2016

해킹은 현대의 지식기반 사회에 심각한 문제를 야기하고 있다. 해킹으로 인한 피해 규모와 피해 금액 또한 꾸준히 증가하고 있다. 따라서 현재까지 해커 또는 해킹과 관련한 많은 연구들이 진행되어 왔다. 기존 연구에 의하면 해커들은 재미와 같은 내재적 동기에 의해 해킹 기술을 습득하며, 주로 해킹 커뮤니티에서 기술을 습득하는 것으로 알려져 왔다. 또한 최근에는 재미나 흥미 등 내재적 동기는 물론 금전적 보상 등과 같은 외재적 동기도 증가하고 있다고 한다. 그러나 현재까지의 관련 연구들은 표본 수집의 한계로 인해 정성적 연구에 치우쳐 왔다. 따라서 본 연구는 기존 연구의 한계를 극복하기 위해 해킹 커뮤니티에 소속된 멤버들을 대상으로 계획된 행동이론을 기반으로 한 정량적 연구를 진행했으며, 동기적, 사회적 그리고 환경적 요인이 해커의 학습에 미치는 영향 요인을 규명하였다. 본 연구는 보안 및 해킹 기술을 습득하기 위해 결성된 대학정보보호연합 동아리를 대상으로 2015년 5월에 약 2주 간 설문을 진행했다. 회원 전체에게 이메일을 보내 응답한 215개의 설문지를 바탕으로 연구가설을 검증하고 분석했다. 연구 결과, 해킹 기술 습득자들은 해킹 기술 습득이 사회적으로 비윤리적으로 인식되고 있다는 것을 스스로 인지하고 있었으며, 재미나 흥미와 같은 내재적 동기 및 타인의 인정을 추구하는 외재적 동기 모두 학습 태도에 영향을 주었고, 온라인 해킹 커뮤니티의 접근성과 정보 품질과 같은 환경적 특성이 해킹 기술 습득에 영향을 주는 것으로 나타났다. 본 연구는 학문적으로 해킹은 사회적으로 부정적으로 인식된다는 것을 밝혀내어 비윤리적 연구의 주관적 규범의 방향성에 대한 논의를 확장시켰고, 동기 요인들이 해킹 기술 습득 태도에 영향을 미친다는 점을 실증했다. 또한, 해킹 커뮤니티의 특성이 지각된 행동통제의 선행 요건임을 밝혀내어 계획된 행동이론의 적용 범위를 확장했다. 또한, 실무적으로 해커들을 윤리적 해커(정보보호전문가)로 만들기 위한 윤리 교육의 필요성과 해킹 방지를 위한 처벌의 강화 및 과징금 부과 등이 해커의 행동 변화에 영향을 줄 수 있음을 제시했다.

• Asia pacific journal of information systems
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• 제18권2호
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• pp.41-72
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• 2008

The purpose of this study is the investigation of the effects of user participation, network effect, social influence, and usefulness on stickiness and continued use on Internet communities. In this research, stickiness refers to repeat visit and visit duration to an Internet community. Continued use means the willingness to continue to use an Internet community in the future. Internet community-based companies can earn money through selling the digital contents such as game, music, and avatar, advertizing on internet site, or offering an affiliate marketing. For such money making, stickiness and continued use of Internet users is much more important than the number of Internet users. We tried to answer following three questions. Fist, what is the effects of user participation on stickiness and continued use on Internet communities? Second, by what is user participation formed? Third, are network effect, social influence, and usefulness that was significant at prior research about technology acceptance model(TAM) still significant on internet communities? In this study, user participation, network effect, social influence, and usefulness are independent variables, stickiness is mediating variable, and continued use is dependent variable. Among independent variables, we are focused on user participation. User participation means that Internet user participates in the development of Internet community site (called mini-hompy or blog in Korea). User participation was studied from 1970 to 1997 at the research area of information system. But since 1997 when Internet started to spread to the public, user participation has hardly been studied. Given the importance of user participation at the success of Internet-based companies, it is very meaningful to study the research topic of user participation. To test the proposed model, we used a data set generated from the survey. The survey instrument was designed on the basis of a comprehensive literature review and interviews of experts, and was refined through several rounds of pretests, revisions, and pilot tests. The respondents of survey were the undergraduates and the graduate students who mainly used Internet communities. Data analysis was conducted using 217 respondents(response rate, 97.7 percent). We used structural equation modeling(SEM) implemented in partial least square(PLS). We chose PLS for two reason. First, our model has formative constructs. PLS uses components-based algorithm and can estimated formative constructs. Second, PLS is more appropriate when the research model is in an early stage of development. A review of the literature suggests that empirical tests of user participation is still sparse. The test of model was executed in the order of three research questions. First user participation had the direct effects on stickiness(${\beta}$=0.150, p<0.01) and continued use (${\beta}$=0.119, p<0.05). And user participation, as a partial mediation model, had a indirect effect on continued use mediated through stickiness (${\beta}$=0.007, p<0.05). Second, optional participation and prosuming participation significantly formed user participation. Optional participation, with a path magnitude as high as 0.986 (p<0.001), is a key determinant for the strength of user participation. Third, Network effect (${\beta}$=0.236, p<0.001). social influence (${\beta}$=0.135, p<0.05), and usefulness (${\beta}$=0.343, p<0.001) had directly significant impacts on stickiness. But network effect and social influence, as a full mediation model, had both indirectly significant impacts on continued use mediated through stickiness (${\beta}$=0.11, p<0.001, and ${\beta}$=0.063, p<0.05, respectively). Compared with this result, usefulness, as a partial mediation model, had a direct impact on continued use and a indirect impact on continued use mediated through stickiness. This study has three contributions. First this is the first empirical study showing that user participation is the significant driver of continued use. The researchers of information system have hardly studies user participation since late 1990s. And the researchers of marketing have studied a few lately. Second, this study enhanced the understanding of user participation. Up to recently, user participation has been studied from the bipolar viewpoint of participation v.s non-participation. Also, even the study on participation has been studied from the point of limited optional participation. But, this study proved the existence of prosuming participation to design and produce products or services, besides optional participation. And this study empirically proved that optional participation and prosuming participation were the key determinant for user participation. Third, our study compliments traditional studies of TAM. According prior literature about of TAM, the constructs of network effect, social influence, and usefulness had effects on the technology adoption. This study proved that these constructs still are significant on Internet communities.

• Asia pacific journal of information systems
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• 제19권3호
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• pp.51-67
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• 2009

Developing an agile recommender system for nomadic users has been regarded as a promising application in mobile and ubiquitous settings. To increase the quality of personalized recommendation in terms of accuracy and elapsed time, estimating future context of the user in a correct way is highly crucial. Traditionally, time series analysis and Makovian process have been adopted for such forecasting. However, these methods are not adequate in predicting context data, only because most of context data are represented as nominal scale. To resolve these limitations, the alignment-prediction algorithm has been suggested for context prediction, especially for future context from the low-level context. Recently, an ontological approach has been proposed for guided context prediction without context history. However, due to variety of context information, acquiring sufficient context prediction knowledge a priori is not easy in most of service domains. Hence, the purpose of this paper is to propose a novel context prediction methodology, which does not require a priori knowledge, and to increase accuracy and decrease elapsed time for service response. To do so, we have newly developed pattern-based context prediction approach. First of ail, a set of individual rules is derived from each context attribute using context history. Then a pattern consisted of results from reasoning individual rules, is developed for pattern learning. If at least one context property matches, say R, then regard the pattern as right. If the pattern is new, add right pattern, set the value of mismatched properties = 0, freq = 1 and w(R, 1). Otherwise, increase the frequency of the matched right pattern by 1 and then set w(R,freq). After finishing training, if the frequency is greater than a threshold value, then save the right pattern in knowledge base. On the other hand, if at least one context property matches, say W, then regard the pattern as wrong. If the pattern is new, modify the result into wrong answer, add right pattern, and set frequency to 1 and w(W, 1). Or, increase the matched wrong pattern's frequency by 1 and then set w(W, freq). After finishing training, if the frequency value is greater than a threshold level, then save the wrong pattern on the knowledge basis. Then, context prediction is performed with combinatorial rules as follows: first, identify current context. Second, find matched patterns from right patterns. If there is no pattern matched, then find a matching pattern from wrong patterns. If a matching pattern is not found, then choose one context property whose predictability is higher than that of any other properties. To show the feasibility of the methodology proposed in this paper, we collected actual context history from the travelers who had visited the largest amusement park in Korea. As a result, 400 context records were collected in 2009. Then we randomly selected 70% of the records as training data. The rest were selected as testing data. To examine the performance of the methodology, prediction accuracy and elapsed time were chosen as measures. We compared the performance with case-based reasoning and voting methods. Through a simulation test, we conclude that our methodology is clearly better than CBR and voting methods in terms of accuracy and elapsed time. This shows that the methodology is relatively valid and scalable. As a second round of the experiment, we compared a full model to a partial model. A full model indicates that right and wrong patterns are used for reasoning the future context. On the other hand, a partial model means that the reasoning is performed only with right patterns, which is generally adopted in the legacy alignment-prediction method. It turned out that a full model is better than a partial model in terms of the accuracy while partial model is better when considering elapsed time. As a last experiment, we took into our consideration potential privacy problems that might arise among the users. To mediate such concern, we excluded such context properties as date of tour and user profiles such as gender and age. The outcome shows that preserving privacy is endurable. Contributions of this paper are as follows: First, academically, we have improved sequential matching methods to predict accuracy and service time by considering individual rules of each context property and learning from wrong patterns. Second, the proposed method is found to be quite effective for privacy preserving applications, which are frequently required by B2C context-aware services; the privacy preserving system applying the proposed method successfully can also decrease elapsed time. Hence, the method is very practical in establishing privacy preserving context-aware services. Our future research issues taking into account some limitations in this paper can be summarized as follows. First, user acceptance or usability will be tested with actual users in order to prove the value of the prototype system. Second, we will apply the proposed method to more general application domains as this paper focused on tourism in amusement park.

• Asia pacific journal of information systems
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• 제19권1호
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• pp.1-31
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• 2009

This paper empirically examines factors that potentially influence the success of a Web-based semantic search engine. A research model has been proposed that shows the impact of quality-related factors upon the effectiveness of a semantic search engine, based on DeLone and McLean's(2003) information systems success model. An empirical study has been conducted to test hypotheses formulated around the research model, and statistical methods were applied to analyze gathered data and draw conclusions. Implications for academics and practitioners are offered based on the findings of the study. The proposed model includes three quality dimensions of a Web-based semantic search engine-namely, information quality, system quality and service quality. These three dimensions each have measures designed to collectively assess the respective dimension. The model is intended to examine the relationship between measures of these quality dimensions and measures of two dependent constructs, including individuals' net benefit and user satisfaction. Individuals' net benefit was measured by the extent to which the user's information needs were adequately met, whereas user satisfaction was measured by a combination of the perceived satisfaction with search results and the perceived satisfaction with the overall system. A total of 23 hypotheses have been formulated around the model, and a questionnaire survey has been conducted using a functional semantic search website created by KT and Hakia, so as to collect data to validate the model. Copies of a questionnaire form were handed out in person to 160 research associates and employees working in the area of designing and developing semantic search engines. Those who received the form, 148 respondents returned valid responses. The survey form asked respondents to use the given website to answer questions concerning the system. The results of the empirical study have indicated that, of the three quality dimensions, information quality was found to have the strongest association with the effectiveness of a Web-based semantic search engine. This finding is consistent with the observation in the literature that the aspects of the information quality should serve as a basis for evaluating the search outcomes from a semantic search engine. Measures under the information quality dimension that have a positive effect on informational gratification and user satisfaction were found to be recall and currency. Under the system quality dimension, response time and interactivity, were positively related to informational gratification. On the other hand, only one measure under the service quality dimension, reliability was found to have a positive relationship with user satisfaction. The results were based on the seven hypotheses that have been accepted. One may wonder why 15 out of the 23 hypotheses have been rejected and question the theoretical soundness of the model. However, the correlations between independent variables and dependent variables came out to be fairly high. This suggests that the structural equation model yielded results inconsistent with those of coefficient analysis, because the structural equation model intends to examine the relationship among independent variables as well as the relationship between independent variables and dependent variables. The findings offer some useful implications for owners of a semantic search engine, as far as the design and maintenance of the website is concerned. First, the system should be designed to respond to the user's query as fast as possible. Also it should be designed to support the search process by recommending, revising, and choosing a search query, so as to maximize users' interactions with the system. Second, the system should present search results with maximum recall and currency to effectively meet the users' expectations. Third, it should be capable of providing online services in a reliable and trustworthy manner. Finally, effective increase in user satisfaction requires the improvement of quality factors associated with a semantic search engine, which would in turn help increase the informational gratification for users. The proposed model can serve as a useful framework for measuring the success of a Web-based semantic search engine. Applying the search engine success framework to the measurement of search engine effectiveness has the potential to provide an outline of what areas of a semantic search engine needs improvement, in order to better meet information needs of users. Further research will be needed to make this idea a reality.

• 핵의학기술
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• 제20권1호
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• pp.37-41
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• 2016

정도관리(Quality Control)는 오차를 최소한으로 하여 검사의 신뢰도를 증진 시키는 것을 목적으로 하고 있으며 이러한 정도관리 활동을 통해 환자의 진단과 치료방침에 영향을 주는 핵의학 혈액 검사의 신뢰도가 확보되고 있다. 이에 연구자들은 신뢰도 향상의 추가적인 기법으로 건강검진 수검자를 대상으로 시행한 핵의학 혈액검사의 모집단 분포를 이용한 통계적 품질관리의 유용성을 평가해 보고자 한다. 2014년 1월부터 2014년 12월까지 서울아산병원 건강증진센터를 이용한 건강검진 수검자 41,341명을 대상으로 핵의학 혈액 검사 12종목에 대해 통계 분석을 시행 하였다. 통계분석은 핵의학 혈액 검사 12종목에 대한 결과 보고 치를 참고치 이내, 참고치 이상, 참고치 이하의 세 가지 그룹의 월간 백분율로 구분하여 모집단 분포의 평균값과 표준편차, 그리고 표준편차 지수(Standard Deviation Index: SDI)를 산출 하였고 그 결과 모집단 분포의 표준편차는 모든 그룹에서 대부분 ${\pm}2SD$ 이내의 결과를 보였다. 건강검진 수검자에 대한 핵의학 혈액검사 12종목(AFP, CEA, CA19-9, CA125, PSA, TSH, FT4, Anti-Tg-Ab, Anti-TPO-Ab, Calcitonin, 25-OH-VitD3, Insulin)의 모집단 분포를 분석한 결과 월간 백분율의 표준편차 지수(SDI)가 ${\pm}2.0$ 이상인 경우는, 1월과 3월 Insulin검사에서 각각 2.3, 2.4, 5월 Anti-Tg-Ab검사에서 2.2, 그리고 9월 CA19-9에서 2.2의 결과를 보였다. 이는 검사 Kit 시약의 이상 (동위원소 시약의 최대 결합률 저하), 검사반응 시간의 저하가 원인 이었다. 연구대상이 되는 전체의 속성을 포함하고 모집단 분포의 특성을 이용한 통계적 품질관리는 검사실에서 시행하고 있는 내부정도관리 프로그램을 보완하는 역할을 할 수 있으리라 생각된다.