• Journal of Environmental Health Sciences
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• v.11 no.1
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• pp.9-14
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• 1985

This experiment was carried out to study on the effect of SO$_2$ gas to chemical composition of tobacco leaves during flue-curing. The results were as follows: SO$_2$ gas in briquet was the major factor to damage with tobacco leaves. The damage only occured in a presence of moisture in tobacco leaves, it did not occured after color fix'lng stage which is a little leaf moisture. The danger of damage to tobacco leaves lies in 10ppm of SO$_2$ gas concentration. Follow with the SO$_2$ gas concentration increased, sugar and nitrogen contents became higher, polyphenol contents were loss, and the quality of tobacco leaves declined.

• International Journal of Safety
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• v.9 no.1
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• pp.12-20
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• 2010

In this study, a series of random field test and dynamic analysis in the time domain were carried out in order to find in the reason of fatigue damage of the main and the secondary members in the 3-span continuous steel plate girder railway bridge being under in service over 60 years. From the measured and the analyzed results, the stress distribution patterns were investigated for the members with fatigue damage. In addition, global and local numerical stress analysis was performed for the members damaged severely by corrosion, to estimate variation of the distribution by corrosion. Finally, a reasonable cut-off ratio in the steel plate railway bridge will be proposed by analyzing the equivalent stress ranges according the ratio.

• Structural Engineering and Mechanics
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• v.64 no.5
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• pp.557-566
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• 2017

Fiber reinforced polymer (FRP) sheets are the most efficient structural materials in terms of strength to weight ratio and its application in strengthening and retrofitting of a structure or structural elements are inevitable. The performance enhancement of structural elements without increasing the cross sectional area and flexible nature are the major advantages of FRP in retrofitting/strengthening work. This research article presents a detailed study on the inelastic response of conventional and retrofitted Reinforced Concrete (RC) frames using Carbon Fibre Reinforced Polymers (CFRP) and Glass Fiber Reinforced Polymers (GFRP) subjected to quasi-static loading. The hysteretic behaviour, stiffness degradation, energy dissipation and damage index are the parameters employed to analyse the efficacy of FRP strengthening of brick in-filled RC frames. Repair and retrofitting of brick infilled RC frame shows an improved load carrying and damage tolerance capacity than control frame.

• Biomedical Science Letters
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• v.11 no.2
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• pp.103-108
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• 2005

2-Deoxyribonolactone (dL) arises as a major DNA damage induced by a variety of agents, involving free radical attack and oxidation of C1'-deoxyribose in DNA. We investigated whether dL lesions can be repaired in mammalian cells and the mechanisms underlying the role of DNA polymerase $\beta$ in processing of dL lesions. Pol $\beta$ appeared to be trapped by dL residues, resulting in stable DNA-protein cross-links. However, repair DNA synthesis at site-specific dL sites occurred effectively in cell-free extracts, but predominantly accompanied by long-patch base excision repair (BER) pathway. Reconstitution of long-patch BER demonstrated that FEN1 was capable of removing the displaced flap DNA containing a 5'-dL residue. Cellular repair of dL lesions was largely dependent on the DNA polymerase activity of Pol $\beta$. Our observations reveal repair mechanisms of dL and define how mammalian cells prevent cytotoxic effects of oxidative DNA lesions that may threaten the genetic integrity of DNA.

• Smart Structures and Systems
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• v.6 no.9
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• pp.1079-1105
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• 2010

Railway transport of goods and passengers is effective in terms of energy conservation and travel time savings. Safety and ride quality have become important issues as train speeds have increased. Due to increased speeds, minor damage to railway structures and abnormal interactions between trains and structures have given rise to increasingly serious accidents. Therefore, structural health and operational conditions must be monitored continuously in all service environments. Currently, various health and operation management systems are being developed and these are reducing both maintenance frequency and costs associated with disassembly. In this review, major damage and malfunctions and their locations are first analyzed based on numerous references. Then advanced train health and operation management technologies are classified into wayside detection methods and advanced integrated sensor methods and their operating principle and functions are reviewed and analyzed.

• 한국기계연구소 소보
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• s.19
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• pp.43-52
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• 1989

Material damage of Unifiner Change Heater: Tube used for nearly 20 years was evaluated and Mechanical tests such as tensile tests and creep-rupture tests were conducted to predict the residual life. After the investigation, any major damage or degradation was not found except the welded zone. Microstructural observation showed that most of delta-ferrite was transformed. to sigma-phase and consequently, the ductility was very much reduced. A KLA(Knife-Line Attack) crack with 60mm in length and 2.8mm in depth was found just near the welded zone, which is believed to be caused by intergranular corrosion. Creep-rupture tests, which are very essential to predict the residual life, showed that both used base and weld metals have similar results with the reference data.

• Korean Journal of Human Ecology
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• v.15 no.5
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• pp.849-858
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• 2006

This research aimed to survey problems related to the elderly's purchasing trends and habitual use of health food; it was in order to effectively prevent the monetary and health damage to the elderly of health foods. In February 2006, the data were collected from 271 of the elderly people living in Goyang-si, Kyunggi-Do. The results of the study indicated: first, more than 50% of the respondents had much interest in health foods, and 42.8% of them answered they were taking health foods. Second, about 62% of 116 respondents who were taking health foods were taking one kind of them, for the purpose of maintaining and improving their health condition. Third, the major information regarding health foods was acquired from their family members, relatives and friends, or TV, radio and journals. Lastly, 75% of respondents even did not know whether there was a relief system for damage related to health foods.

• Earthquakes and Structures
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• v.26 no.4
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• pp.269-283
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• 2024

When a reinforced concrete (RC) structure is exposed to a corrosive environment for an extended period of time, the material qualities deteriorate, resulting in a loss in seismic performance. Engineered Cementitious Composites (ECC) have been used to reinforce the corroded RC structure, which can achieve reinforcement effectiveness for a small change in cross-section size. In this work, finite element models of unjacketed RC pier and ECC jacketed pier were established and verified by experimental tests, with the buckling effect of longitudinal reinforcement considered. Compared with the unjacketed pier, the displacement of the pier top of the ECC jacketed pier was reduced by about 9.52% under earthquake action. In the case of moderate and major earthquakes, the probability of exceedance of ECC jacketed pier is significantly reduced. For the case of rare earthquake loading, with the ECC jacket, the e of the pier experiencing serious damage and complete damage states is reduced by 10.29% and 29.78%, respectively.

• Journal of Wetlands Research
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• v.22 no.4
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• pp.302-311
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• 2020

There are limitations to cope with flood damage by structural strategies alone because both frequency and intensity of floods are increasing due to climate change. Therefore, it is one of the necessary factors in the nonstructural countermeasures to collect and analyze historical flood damage records for the future flood damage assessments. In order to estimate flood damage costs in Gyeongsangbuk-do where severe flood damage occurs frequently due to geographical and climatic effects, this paper has performed the regression analysis on flood damage records over the past 20 years (1999-2018) by rainfall characteristics, which is one of the major causes of flood damage. This paper has then examined the relationship between the terrain features and rainfall characteristics in the regional regression functions, and also estimated the flood damage risk for 100-year rainfall by using the regional regression functions presented for the 22 administrative districts in Gyeongsangbuk-do excluding Ulleung-gun. The flood damage assessment shows that the relatively high damage risk is estimated for county areas adjacent to the eastern coast in Gyeongsangbuk-do. The regional damage estimate functions in this paper are expected to be used as one of the nonstructural countermeasures to estimate flood damage risk for the design or forecasting rainfall data.

• Toxicological Research
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• v.21 no.3
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• pp.195-208
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• 2005

Diabetes is a major cause of morbidity and mortality, and associated with a high risk of atherosclerosis, and liver, kidney, nerve and tissue damage. Defective insulin secretion in pancreas and/or insulin resistance in peripheral tissues is a central component of diabetes. It is well established that, regardless of the degree of muscle insulin resistance, glucose levels in diabetic and non-diabetic individuals are determined by the rate of hepatic glucose production. Moreover recently studies using liver-specific insulin receptor knockout mice show the paramount role of the liver in insulin resistance and diabetes. Insulin exerts a multifaceted and highly integrated series of actions via its intracellular signaling systems. The first major section of this review defines the major insulin-mediated signaling pathways including phosphatidylinositol 3-kinase and mitogen activated protein kinases. The second major section of the review presents a summary and evaluation of methods for determination of the role and function of signaling pathways, including methods for determination of kinase phosphorylation, the use of pharmacological inhibitors of kinase and dominant-negative kinase constructs, and the application of new RNA interference methods.