• 제목/요약/키워드: Magnolia

검색결과 287건 처리시간 0.216초

후박(厚朴)의 생약학적 연구 (Pharmacognostical Studies on the ‘Hoo Bak’)

  • 박종희;난파항웅
    • 생약학회지
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    • 제25권2호
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    • pp.188-193
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    • 1994
  • 'Hoo Bak' is one of the Chinese crude drugs used mainly to cure a headache, apoplexy and dyspepsia. With regard to the botanical origin of 'Hoo Bak', it has been considered to be Machilus thunbergii of Lauraceae in Korea. But there has no pharmacognostical confirmation on it. To clarify the botanical origin of 'Hoo Bak', the anatomical characteristics of the bark of Machilus thunbergii, Magnolia officinalis and Magnolia obovata were studied. As a result, it was clarified that 'Hoo Bak' from Korea was the bark of Machilus thunbergii of Lauraceae.

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형태특징 및 RAPD분석에 의한 후박(厚朴) 약재의 진위감별 (Discrimination of Genuines and Misuses of Hu-Bak medicines by Morphological Characters and Random Amplified Polymorphic DNA Analysis)

  • 이미영;김홍준;주영승;고병섭
    • 한국한의학연구원논문집
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    • 제9권2호
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    • pp.83-94
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    • 2003
  • For identification of genuine and misuse samples of Hu-Bak medicines, an morphological characters, and RAPD (random amplified polymorphic DNA) were performed. In this study, three samples were collected, of which two were genuine and one was misuse sample. Genuine samples of 'Hu-Bak' were Magnolia obovata Thunberg and Magnolia officinalis Rehder et Wilson. Misuse samples was Machilus thunbergii S. et Z. In the morphological characters, M. obovata Thunberg and M. officinalis Rehder et Wilson were similar, but M. thunbergii S. et Z. was different with cortex, cambium, and fibrous layer. The result of RAPD analysis, seven primers can distinguish between genuines and counterfeit samples of Hu-Bak medicines.

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목련(Magnolia kobus DC. var. borealis Sarg.)의 추출성분 - 각 부위의 리그난 - (Extractives of Magnolia kobus DC. var. borealis Sarg. - Lignans from the each tissue -)

  • 김윤근
    • Journal of the Korean Wood Science and Technology
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    • 제26권4호
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    • pp.61-70
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    • 1998
  • Xylem, bark and flower buds of Magnolia kobus DC. var. borealis Sarg. were extracted with ethanol. And then the ethanol extracts were fractionated with diethyl ether. The lignans structure of the diethyl ether fractions were determined by spectroscopic methods. The results are summarized as follows : 1. Three compounds, aschantinn(X-I), yangambin(X-II), (-)syringaresinol(X-III), tetrahydrofurofuranoid lignans were isolated from the xylem. 2. Five compounds were isolated from the bark. These are all tetrahydrofurofuranoid lignans, aschantin(B-I), yangambin(B-II), medioresinol(B-III), (+)syringaresinol(B-IV), and tetrahydrofuranoid, kobusinol B(B-V). 3. Three tetrahydrofurofuranoid lignans, kobusin(F-I), aschantin(F-II), yangambin(F-III) were isolated from the flower buds. 4. Isolated lignans from the each tissue were two types of tetrahydrofurofuran type and tetrahydrofuran type. 5. The tetrahydrofurofuranoid lignans were five compounds such as kobusin, aschantin, yangambin, medioresinol, and syringaresinol, while the tetrahydrofuranoid lignans was kobusinol B. 6. Most of these lignans were substituted with the methylenedioxy or methoxyl groups.

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Anti-platelet Effect of the Phenolic Constituents Isolated from the Leaves of Magnolia obovata

  • Pyo, Mi-Kyung;Koo, Yean-Kyoung;YunChoi, Hye-Sook
    • Natural Product Sciences
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    • 제8권4호
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    • pp.147-151
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    • 2002
  • In the course of our work on anti-platelet constituents from plants, eight phenolic compounds, $({\pm})-syringaresinol$ (1), 4-hydroxybenzaldehyde (2), 4-hydroxybenzoic acid (3), vanillic acid (4), 4-hydroxy cinnamic acid (5), quercetin 3-O-rhamnoside (6), rutin (7), and quercetin $3-(2^G-rhamnosylrutinoside)$ (8) were isolated from the methanol extract of the leaves of Magnolia obovata. The compounds were identified based on the spectroscopic data. Compound 2, 3, 5, 6, 7 and 8 were isolated for the first time from genus Magnolia. 1 and 6 showed same order of inhibitory potencies as acetylsalicylic acid (ASA) to rat platelet aggregation induced by all the stimulators tested. The remaining six compounds showed only mild effects.

함박꽃나무(Magnolia sieboldii)의 추출성분 (Extractives from Magnolia siebildii)

  • 최인호;이학주;최돈하;박재인;최태호
    • Journal of the Korean Wood Science and Technology
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    • 제32권2호
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    • pp.33-39
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    • 2004
  • 함박꽃나무 수피 및 목부의 EtOH 조추출물로부터 prep. TLC, silica gel 및 Sephadex LH-20 칼럼 크로마토그라피를 이용하여 4종의 화합물을 단리하였다. 이들 화합물들은 NMR, MS 등의 기기분석에 의해 sesquiterpene lactone 구조의 costunolide (I)를 비롯하여, 리그난 배당체 화합물인 syringin (II)과 1, 2-dihydroxyxanthone (III) 및 vanillic acid (IV)으로 각각 동정하였다.

후박 및 은행잎 추출물의 향균, 향염 및 세포활성도에 미치는 영향 (BIOLOGICAL EFFECT OF MAGNOLIA AND GINKGO BILOBA EXTRACT TO THE ANTIMICROBIAL, ANTIINFLAMMATORY AND CELLULAR ACTIVITY)

  • 정종평;구영;배기환
    • Journal of Periodontal and Implant Science
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    • 제25권3호
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    • pp.478-486
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    • 1995
  • Periodontal therapy for treatment of periodontitis involves the elimination of bacterial plaque and elimination of the anatomic defects by regenerative procedure. The purpose of this study was to evaluate on the biological effect of magnolia and Ginkgo biloba extract to the antimicrobial, antiinflammatory and cellular activity. Antimicrobial assay was performed with the diffusion method of the extract by measuring of growth inhibitory zone of B. cereus from blood agar plate. Effect of the extract to cellular activity of gingival fibroblast were examined using MTT method and measured the result with optical density on 570nm by ELISA reader. Inhibitory effects of $PGE_2$ production from gingival fibroblast was performed with the addition of $IL-l{\beta}$ and the extract to the well and examined to the product of $PGE_2$ from cell by ELISA reader. In vivo anti-inflammatory effect was performed with injection examined with clinically and histologically for their extent of mecrosis and inflammation. Antimicrobial activity of Magnolia extract showed significantly higher activity than that of control. However, GBE did not showed significant activity to compare with control, and mixture of Magnolia and GBE extract showed significantly higher activity than that of control. The effect of cellular activity to gingival fibroblast showed no significant differences of between control and Magnolia extract. However, GBE showed significantly higher rate of cellular activity to compare with control and even to PDGF-BB, and also showed same degree of cellular activity even though mixed with Magnolia extract. The inhibitory effect of $PGE_2$ production showed significantly reduction of $PGE_2$ production to compare with control, but its inhibitory effect was not much strong to compare with Indomethacin. In vivo, antiinflammatory effect of Magnolia extract to P. gingivalis injection of Hamster buccal check showed significantly reduction of inflammatory cell infiltration and tissue necrosis, but GBE showed no effect on the inhibition of inflammatory process. These results suggested that Magnolia and GBE extract possessed different kind of biological activity and also can be compensated on their activity with each other for elimination of bacterial plaque and anatonical defect.

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관상식물 삽목발근에 있어서 NAA, IBA 및 Ethychlozate의 발근촉진효과와 그 생리학적연구 (The Promotive Effect of NAA, IBA and Ethychlozate on Rooting Cuttings of Certain Ornamental Plants and Some Physiological Studies.)

  • 정해준;곽병화
    • 자연과학논문집
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    • 제1권
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    • pp.115-198
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    • 1987
  • The present studies were undertaken to elucidate the influence of auxins, auxin-like substance-ethychlozate ("Figaron"),and pH and sort of rooting media on rooted propagation of certainornamental woody plant cuttings, and to see possible changes in internal compositions characterizing after root-promoting treatment as the cutting stage proceeded. The experimental check-up srevealed and summarized as seen in the following;I. Effect of three different auxin treatments on rooting cuttings: 1) Promotive influence of auxin varied according to different concentration levels, hours of dipping treatment of the auxins, and kind of plants. The greatest effect was obtained for Forsythia ksreana with NAA and IBA, for Ligustrurn obtusifolium var. variegatum with NAA and ethychlozate, for Hydrangea macrophylla, Magnolia kobus, and Magnolia liliflora with NAA, lBA and ethychlozate also. The most effective level of the promotive agents was found 200mg/l for NAA, 1000mg/l for IBA, and 200mg/l for ethychlozate. For Weigela florida and Gardenia jasminoides, range of the most effective level was shown relatively wide spread. 2) NAA was more effective at its optimal level of the rooting agent than ethychiozate for Weigela florida, Viburnum awabuki, Forsythia koreana, Acer palmatum 'Nomura', Bouga invillea glabra, Elaeagnus umbellata, Prunus tomentosa, Ligustrum obtusifolium, Pyracantha coccinea, Cestrum noctu rnum, Hydrangea macrophylla, Codiaeum variegatum, Rhododen dron lateritium, and Ilex crenata var. macrophylla, and yet ethychlozate was found either as equally as effective or more so than NAA for Zebrina pendula, Hibiscus syriacus, Fatshedera lizei, Schefflera arboricola, Campsis grandiflo ra, Ixora chinensis, Euonymus japonica, and Magnolia liliflora. On the contrary, no the auxin effect was noted with Lagerstroemia indica, Trachelospermum asiaticum, and Syringa vulgaris. This probably indicates that these species are genetically different for the auxin response.II. Effect of different pH and sorts of cutting media on rooting cuttings: 1) Bougainvillea showed best in rooting for the number and dry weight at pH 6.5, more with ethychlozate than NAA, while Ligustrum did at pH 5.0 more with NAA than ethychlozate. pH 4.0 medium resulted in the best rooting for Rhododendron with NAA, more than ethychlozate. 2) Use of cutting medium with peat: perlite: vermiculite = 1:1:1 showed to give the greatest rooting percent and dry weight, apart from considering the number of roots. This apparently meant the fact that cutting medium has more to do with root growth than root differentiation. Rhododendron yet showed results with cutting media that use of peat: perlite = 2:1 mixed is more effective on rooting than using peat alone.III. Effect of auxinic treatments on rooting cuttings and change in some cutting compositions: 1) Under the climatic conditions of July having temperature $26.3\pm$$2.4^{\circ}C$for cutting bed, new roots of Magnolia started to show up generally 20 days after the cutting was made, whereas Cestrum did much earlier than that, namely 14 days after. 2) Although total carbohydrate content of Magnolia cuttings showed no marked change without auxin treatment, it did so with the treatment, especially 30 days after the start of cutting. Cestrum cuttings demonstrated a gradual in crease in total carbohydrate content as rooting took place, and the content became reduced more with auxin than with out, just about when rooting proceeded to 14 days after the start of cutting. 3) Magnolia generally showed an increase in total nitrogen content as rooting proceeded more, and Cestrum showed a decrease in total nitrogen of cuttings. The auxin treatment exhibited no pertinent relation with change in plant nitro gen when rooting is promoted with auxin treatment. 4) An abrupt drop of total sugar and reducing sugar was noticed as Magnolia rooting started, and this reduction was parti cularly outstanding with auxin treatment. Starch content also was decreased in the later stage of cutting with auxin treatment, and was rather increased without auxin. Although sugar content soon increased as cutting started with auxin treatment in the case of Cestrum, it became reduced after rooting took place. 5) Total phenol content increased with rooting, and this was especially true when rooting started. This increase was reversed somehow regardless of auxin treatment. A decrease in phenol of Magnolia was found more striking with auxin than without in the later stage of the cutting period. 6)Avena coleoptile test for auxin-like substances presented the physiologically active factor is more in easy-to-root Magnolia liliflora than hard-to-root Magnolia kobus, and the activity of auxin-like substances was much increased with auxin treatment. The increase in the growth promoting substances was markedly pronounced when rooting just started. The active growth substances decreased in the later stage of cutting, and certain inhibitory substances started appearing. Cestrum also showed physiologically similar growth promoting substances accompanying auxin-like active substances if auxin is treated, and some strong inhibitory substances seemed to appear in the later stage of cutting. 7) Mung-bean-rooting test indicated biologically that endogenous growth substances in Magnolia all promoted mung-bean rooting, and activity of the growth substances apparently stimulated mung-bean rooting with auxin more than without. Here auxin treatment seemed to give a rise to an increased activity of endogenous growth substances in cuttings. This activity was found much greater with either NAA or IBA than ethychlozate, and showed its peak of the activity when rooting first started taking place. Certain inhibitory substances for Avena coleoptile growth strongly promoted mung-bean rooting, and it was also much like in the case of Cestrum.

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신이화(辛夷花, Magnoliae Flos)추출물의 화장품약리활성 및 항염증효과에 관한 연구 (Study on Cosmeceutical Activities and Anti-inflammatory Activities of Magnolia biondii Extracts)

  • 김영훈;성지연;서교성;신재천;김병소;염정현;이진태
    • 생명과학회지
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    • 제22권6호
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    • pp.730-735
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    • 2012
  • 본 연구에서는 신이화에 함유된 물질을 열수와 에탄올을 이용하여 추출한 후 화장품약리활성 및 항염증효과를 확인하고, 화장품 및 바이오산업에 적용하기 위한 천연소재로써의 이용 가능성을 살펴보았다. DPPH 라디칼 소거능 실험결과 농도의존적으로 소거능 효과를 보이며, 열수추출물의 경우 5,000 ug/ml 농도에서 대조군인 BHA보다 우수한 효능을 보였다. SOD 유사활성에서는 농도가 증가할수록 유사활성이 증가하는 것을 확인할 수 있었고, 5,000 ug/ml에서 열수추출물의 경우 85% 유사활성을 나타내었고, 에탄올 추출물의 경우 43%의 유사활성을 나타내었다. Xanthine oxidase 저해능 실험에서도 5,000 ug/ml 농도에서 대조군 BHA 보다 높은 저해능을 효여 우수한 항산화효과를 보였으며, 합성항산화제를 대체할 수 있는 천연항산화제로 사용이 가능할 것으로 사료된다. 항염증효과를 확인하기 위하여 NO 저해 활성 및 iNOS 발현량을 측정하였는데, 열수와 에탄올 추출물 모두 농도가 증가할 수로 NO 저해활성과 iNOS 발현량이 감소하여 우수한 항염증효과를 보였다. 이상의 결과에서 신이화 열수추출물과 에탄올추출물은 우수한 화장품약리활성 및 항염증효과가 있음을 확인할 수 있었고, 안티에이징 및 트러블 피부 개선 화장품 소재로서의 가능성을 확인할 수 있었다.

Characteristics of Volatile Components from Magnolia ovobata Thunb. by Different Analysis Methods

  • Chung, Hae-Gon;Bang, Jin-Ki;Kim, Geum-Soog;Seong, Nak-Sul;Cho, Joon-Hyeong;Kim, Seong-Min
    • 한국약용작물학회지
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    • 제12권2호
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    • pp.102-107
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    • 2004
  • This study was carried out to establish an optimum method for identifying the volatile components of Magnolia ovobata Thunb. using the dynamic headspace (Purge & Trap) and simultaneous distillation and extraction (SDE) method. Between the two different identification analysis, the volatile components were more easily detected in the SDE than the Purge & Trap method. Among the identified volatile components, the 12 compounds were detected to have similar retention times and match quality within the 45 minutes in both identification methods. The maximum values of the major volatile components were detected differently by SDE and (Purge & Trap) method such as ${\alpha}-pinene$ (3.4, 18.2%), ${\beta}-pinene$ (3.5, 10.3%), l-limonene (5.2, 15.4%). These results indicated that the Dynamic Headspace (Purge & Trap) was much more reliable method for identifying the volatile components of Magnolia ovobata Thunb. as compared to the SDE method.