• Title/Summary/Keyword: MaaS

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$^{99m}TC-MAA$ Pulmonary Perfusion Scan in the Canine Single Luhg Transplant (개에서 시행한 한쪽 이식 폐의 $^{99m}TC-MAA$ 관류스캔)

  • Zeon, S.K.;Ryu, J.G.;Park, C.K.;Yoo, Y.S.;Jung, D.S.;Lee, J.K.
    • The Korean Journal of Nuclear Medicine
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    • v.31 no.3
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    • pp.365-371
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    • 1997
  • The aim of this study is to evaluate the efficiency of the pulmonary perfusion scan(Pp scan) in the experimental animal single lung transplantation. Eight left lung transplanted mongrel dogs were included in this study. The serial Pp scan with 111MBq $^{99m}TC-MAA$ were done at the periods of immediate postoperative period, POD 3 days, and POD 10-14 days and finally autopsy was done in each cases. The transplanted lung perfusion was analysed as a percentage radioactivity of trans planted/native lung(T/N) ratio. The Pp scan of a donor mongrel dog was used as a reference(left/right lung (T/N) ratio 85.2%). The average T/N ratio of all cases on immediate postoperative state(reperfusion injury) : 19.2%, three acute rejections. 12.6%, three bronchial dehiscences 6.1% and two pulmonary thromboses : 2.0%. Two cases showed moderate improvement of reperfusion injury as increasing the T/N ratio in POD 3 days Pp scan. The T/N ratio showed sequentially decreased in six cases. As a conclusion, the Pp scan could be a non-invasive method in the evaluation of the experimental one-lung transplanted mongrel dog.

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A Study on the Establishment of Education and Training Program for Urban Air Mobility(UAM) Pilot in Korea (국내 도심항공모빌리티(UAM) 조종사 교육·훈련제도 수립 방안 연구)

  • Young-jin Cho;Chul Park;Se-Hoon Yim
    • Journal of Advanced Navigation Technology
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    • v.27 no.4
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    • pp.330-336
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    • 2023
  • Rapid urbanization is rapidly progressing around the world, and urban problems such as traffic congestion, environmental pollution, and noise pollution are emerging, due to this urban concentration phenomenon, logistics and transportation costs are increasing. Urban Air Mobility(UAM) is a three-dimensional futuristic urban transportation that is expected to become an important transportation axis of smart cities as a service(MaaS) linked to roads, railways, and personal transportation. However, as of July 2023, research on airspace systems, Bertieport design, navigation, and communication for UAM operation is actively being conducted, but little research has been conducted on the concept of pilot education and training and education and training programs. Therefore, this paper aims to present a suitable plan for the domestic pilot training system through SWOT analysis of vertical takeoff and landing(VTOL) pilot education and training programs in the United States and Europe.

Enhanced Formation of Scrapie Prion Protein in Cultured Cells by Treatment with Mycosporine-like Amino Acids (MAAs) (Mycosporine-like amino acids (MAAs) 처리에 따른 배양세포 내 스크래피 프리온 단백질의 형성증가)

  • Lee, Jihyun;Moh, Sang-Hyun;Ryou, Chongsuk;Kim, Dae-Hwan
    • Microbiology and Biotechnology Letters
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    • v.43 no.2
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    • pp.91-96
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    • 2015
  • Prions are proteinaceous infectious particles that cause neurodegenerative diseases, such as scrapie in sheep, bovine spongiform encephalopathy in cattle and Creutzfeldt-Jakob disease (CJD) in humans. Although the detailed process, regarding the abnormal conversion of prion proteins (PrP), remains to be fully elucidated, a number of environmental factors appear to affect the formation of misfolded PrP, termed PrPSc. Because oceanic algae contain mycosporine-like amino acids (MAAs), which exhibit cellular defensive activities under a variety of stress conditions, we investigated the level of PrPSc in prion-infected neuroblastoma cells using mycosporine-glycine, porphyra-334 and shinorine. When judged by the level of protease-resistant PrPSc in western blots, porphyra-334 and shinorine increased the level of PrPSc in cells, but mycosporine-glycine did not. The current results indicate that the MAAs tested in this study enhance the formation of PrPSc.

An Implementation of Non-invasive Blood Pressure System Using Variable Characteristic Ratio (모듈방식의 가정용 혈압 측정 시스템 구현)

  • 이종수;노영아;이상용;박종억;김영길
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.5 no.7
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    • pp.1263-1271
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    • 2001
  • There are two methods in blood pressure measurement ; Invasive methode and Non-invasive method. The Invasive methode can get the 띠cod pressure measurement but, patient feel uncomfortable. So Non-invasive methode used generally. The Oscillometric method is typical Non-Invasive method. This method is commonly used to measure BP in electric sphygmomanometer and has various algorithm. In this paper it is described about a algorithm, it controls, determinates the cuff pressure, and fillers the measured BP data. This system can interface with PC(personal computer) by RS-232 and save the measured data in PC. This system deflates the cuff pressure by Solenoid valve. The main algorithm are oscillometric and maximum amplitude algorithm(MAA). MAA has various measured oscillation, it depends on patient's age, height, weight and arm circumference size. In this paper proposed system can measure Systolic BP, Diastolic BP, and Mean BP using Interpolation, Auto Reinflation algorithm.

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Production Yield Enhancement of Mycosporine-like amino acid(MAA)s in Transformed Microalgae Culture by Radiofrequency (형질전환 미세조류의 고주파 처리 배양을 통한 MAA 생산량 증가)

  • Seo, Hyo Hyun;Song, Mi Young;Kulkarni, Atul;Suh, Sung-Suk;Lee, Taek-Kyun;Moh, Sang Hyun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.6
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    • pp.3799-3804
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    • 2014
  • In sea water, microalgae are exposed to a range of critical environmental conditions. Microalgae are protected from UV-A radiation due to the presence of mycosporine like amino acids(MAAs). Owing to the UV-A absorption properties of MAAs, they are used widely as a UV protecting ingredient in cosmetics. Therefore, there is a need to increase the production yield of MAAs. This study investigated the production yield of MAAs in transformed microalgae by radiofrequency(RF) exposure. Initially, the Glut-1 gene was transformed to Chlamydomonas hedleyi microalgae as a glucose transporter. The biomass was enhanced after Glut-1 gene transformation. In addition, the MAAs production yield was increased during large scale production in bioreactors due to the RF treatment. Therefore, purified extracts of MAAs can be used as a sun block material in the cosmetic industrial field.

Characteristics of Severe Hallux Valgus Deformity with Moderate Intermetatarsal Angle (중등도 중족골간 각을 가지는 중증도 무지외반증의 특징)

  • Park, Chul Hyun;Lee, Woo Chun;Kim, Jung Rae;Lim, Seung Whan
    • Journal of Korean Foot and Ankle Society
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    • v.18 no.4
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    • pp.173-177
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    • 2014
  • Purpose: The purpose of this study is to evaluate the characteristics of hallux valgus with severe hallux valgus angle (HVA) and moderate intermetatarsal angle (IMA) after proximal chevron osteotomy. Materials and Methods: Between January 2008 and December 2010, 41 patients (48 feet) were treated with proximal chevron osteotomy and distal soft tissue procedure for symptomatic severe hallux valgus deformity ($HVA{\geq}40^{\circ}$). Patients were divided into two groups, group M (IMA< $18^{\circ}$) and group S ($IMA{\geq}18^{\circ}$). Mean age of patients was 55.7 years (34~70 years) in group M and 60.0 years (44~78 years) in group S. Mean duration of follow-up was 20.4 months (12~41 months) in group M and 18.5 months (12~35 months) in group S. Radiographic parameters, including HVA, IMA, sesamoid position, metatarsus adductus angle (MAA), and distal metatarsal articular angle (DMAA), were compared between groups. Clinical results were assessed using American Orthopaedic Foot and Ankle Society (AOFAS) score and visual analogue scale (VAS). Recurrence rate at the last follow-up was compared between group M and group S. Results: Preoperative HVA and grade of sesamoid position did not differ between the groups. However, immediate postoperative HVA and grade of sesamoid position were significantly larger in group M. Preoperative MAA and DMAA were significantly larger in group M. No significant difference in AOFAS score and VAS was observed between the groups at the last follow-up. Ten of the 27 feet (37.0%) in group M and two of the 21 feet (9.5%) in group S showed hallux valgus recurrence at the last follow-up. Group M showed a significantly higher recurrence rate than group S. Conclusion: Recurrence rate for severe hallux valgus with moderate IMA is higher than that of severe hallux valgus with severe IMA.

Preparation of Acryl Binder with Silane Type Chain Transfer Agent (실란계 사슬 이동제를 사용한 아크릴 바인더의 제조)

  • Kim, Jin-Gon;Shin, Min-Jae;Shin, Jae-Sup
    • Polymer(Korea)
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    • v.36 no.3
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    • pp.351-356
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    • 2012
  • Acryl binder is a representative organic additive for the manufacture of the display electronic equipment. Acryl binder is usually synthesized by radical copolymerization. Glycidyl methacrylate (GMA), methyl methacrylate (MMA), and methacrylic acid (MAA) were used in this copolymerization of acryl binder. In this study the silane type mercaptane compound was used as a chain transfer agent (CTA) to enhance the adhesion property of the acrylic binder. The CTA used in this experiment was (3-mercaptopropyl) trimethoxysilane (MPTMS). Molecular weight of the copolymer, thickness of the coating, transmittance, and adhesion property were measured. The molecular weight was controlled and the adhesion property was improved by using this silane type chain transfer agent.

Genetic and biochemical evidence for redundant pathways leading to mycosporine-like amino acid biosynthesis in the cyanobacterium Sphaerospermopsis torques-reginae ITEP-024

  • Geraldes, Vanessa;de Medeiros, Livia Soman;Lima, Stella T.;Alvarenga, Danillo Oliveira;Gacesa, Ranko;Long, Paul F.;Fiore, Marli Fatima;Pinto, Ernani
    • ALGAE
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    • v.35 no.2
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    • pp.177-187
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    • 2020
  • Cyanobacteria have been widely reported to produce a variety of UV-absorbing mycosporine-like amino acids (MAAs). Herein, we reported production of the unusual MAA, mycosporine-glycine-alanine (MGA) in the cyanobacterium Sphaerospermopsis torques-reginae ITEP-024 using a newly developed UHPLC-DAD-MS/HRMS (ultra-high performance liquid chromatography-diode array detection-high resolution tandem mass spectrometry) method. MGA had previously been first identified in a red-algae, but S. torques-reginae strain ITEP-024 is the first cyanobacteria to be reported as an MGA producer. Herein, the chemical structure of MGA is fully elucidated from one-dimensional / two-dimensional nuclear magnetic resonance and HRMS data analyses. MAAs are unusually produced constitutively in S. torques-reginae ITEP-024, and this production was further enhanced following UV-irradiance. It has been proposed that MAA biosynthesis proceeds in cyanobacteria from the pentose phosphate pathway intermediate sedoheptulose 7-phosphate. Annotation of a gene cluster encoded in the genome sequence of S. torques-reginae ITEP-024 supports these gene products could catalyse the biosynthesis of MAAs. However, addition of glyphosate to cultures of S. torques-reginae ITEP-024 abolished constitutive and ultra-violet radiation induced production of MGA, shinorine and porphyra-334. This finding supports involvement of the shikimic acid pathway in the biosynthesis of MAAs by this species.

Study on the fabrication and the characterization of 100 nm T-gate InGaAs/InAlAs/GaAs Metamorphic HEMTs (100 nm T-gate의 InGaAs/InAlAs/GaAs metamorphic HEMT 소자 제작 및 특성에 관한 연구)

  • Kim, H.S.;Shin, D.H.;Kim, S.K.;Kim, H.B.;Im, Hyun-Sik;Kim, H.J.
    • Journal of the Korean Vacuum Society
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    • v.15 no.6
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    • pp.637-641
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    • 2006
  • We present the DC and RF characteristics of 100 nm gate length InGaAs/InAlAs/GaAs metamorphic high electron mobility transistors (MHEMTs). We fabricated the T-gate with 100 nm foot print by using a positive resist ZEP520/P (MMA-MAA)/PMMA trilayer by double exposure method. The fabricated 100 nm MHEMT with a $70\;{\mu}m$ unit gate width and two fingers were characterized through do and rf measurements. The maximum drain current density of 465 mA/mm and extrinsic transconductance $(g_m)$ of 844 mS/mm were obtained with our devices. From rf measurements, we obtained the current gain cut-off frequency $(f_T)$ of 192 GHz, and maximum oscillation frequency $(f_{max})$ 310 GHz.

Design and fabrication of a Novel 60 GHz GaAs pHEMT Resistive Double Balanced Star MMIC Mixer (새로운 60 GHz 대역 GaAs pHEMT 저항성 이중평형 Star 혼합기 MMIC의 설계 및 제작)

  • 염경환;고두현
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.15 no.6
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    • pp.608-618
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    • 2004
  • In this paper, modifying the diode star double balanced mixer of Maas, a novel resistive 60 GHz pHEMT MMIC star mixer is suggested. Due to star configuration, troublesome IF balun for ring configuration FET mixer is not necessary. In addition, the sysematic design method of dual balun through EM simulation is suggested rather than the design by inspection as Maas. The mixer circuit is fabricated as MMIC on CPW base using 0.1 um GaAs pHEMT Library of MINT in Dongguk University. The size is 1.5 ${\times}$ 1.5 $\textrm{mm}^2$ and its performance is adjustable by DC supply. It can be operated as both up and down converters and it shows the conversion loss of about 13∼18 ㏈ over the full V-band frequencies.