• 제목/요약/키워드: MX

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SYNTHESIS OF METASTABLE ALLOYS BY ION MIXING IN THE BINARY METAL SYSTEMS AND THEORETICAL MODELLING

  • Liu, B.X.;Zhang, Z.J.;Jin, O.;Pan, F.
    • Journal of the Korean Vacuum Society
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    • v.4 no.S2
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    • pp.148-155
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    • 1995
  • (1) The metastable crystalline(MX) phases formed by ion mixing are classified into 5 types, i.e. the super-saturated solid solutions and the enlarged HCP-I phases reported earlier, and the newly observed FCC-I phases in hcp-based alloys, The FCC-ll and HCP-ll phases in bcc-based alloys. The growth kinetics of the MX phases is discussed. (2) The interfacial free energy in the multilayered films was found to play an important role in ion beam mixing(IM) induced amorphization. By adding sufficient interfaces, amorphous alloys were obtained even in the systems with rather positive heat of formation. (3) Gibbs free energy diagrams of some representative systems were constructed, by calculating the free energy curves of all the competing phases. Steady-state thermal annealing was conducted and the results confirmed the relevance of the constructed diagrams, which were inturn employed to interpret the MX phase formation as well as the glass forming ability upon IM in the binary metal systems.

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Cytokine-cytokine receptor interactions in the highly pathogenic avian influenza H5N1 virus-infected lungs of genetically disparate Ri chicken lines

  • Vu, Thi Hao;Hong, Yeojin;Truong, Anh Duc;Lee, Jiae;Lee, Sooyeon;Song, Ki-Duk;Cha, Jihye;Dang, Hoang Vu;Tran, Ha Thi Thanh;Lillehoj, Hyun S.;Hong, Yeong Ho
    • Animal Bioscience
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    • v.35 no.3
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    • pp.367-376
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    • 2022
  • Objective: The highly pathogenic avian influenza virus (HPAIV) is a threat to the poultry industry as well as the economy and remains a potential source of pandemic infection in humans. Antiviral genes are considered a potential factor for HPAIV resistance. Therefore, in this study, we investigated gene expression related to cytokine-cytokine receptor interactions by comparing resistant and susceptible Ri chicken lines for avian influenza virus infection. Methods: Ri chickens of resistant (Mx/A; BF2/B21) and susceptible (Mx/G; BF2/B13) lines were selected by genotyping the Mx dynamin like GTPase (Mx) and major histocompatibility complex class I antigen BF2 genes. These chickens were then infected with influenza A virus subtype H5N1, and their lung tissues were collected for RNA sequencing. Results: In total, 972 differentially expressed genes (DEGs) were observed between resistant and susceptible Ri chickens, according to the gene ontology and Kyoto encyclopedia of genes and genomes pathways. In particular, DEGs associated with cytokine-cytokine receptor interactions were most abundant. The expression levels of cytokines (interleukin-1β [IL-1β], IL-6, IL-8, and IL-18), chemokines (C-C Motif chemokine ligand 4 [CCL4] and CCL17), interferons (IFN-γ), and IFN-stimulated genes (Mx1, CCL19, 2'-5'-oligoadenylate synthase-like, and protein kinase R) were higher in H5N1-resistant chickens than in H5N1-susceptible chickens. Conclusion: Resistant chickens show stronger immune responses and antiviral activity (cytokines, chemokines, and IFN-stimulated genes) than those of susceptible chickens against HPAIV infection.

Effect of Niobium on Corrosion Fatigue Properties of High Strength Steel

  • Cho, Young-Joo;Cho, Sang-Won;Kim, Jung-Gu
    • Corrosion Science and Technology
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    • v.17 no.2
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    • pp.81-89
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    • 2018
  • In this study, the effect of Nb alloying element on the corrosion fatigue properties of high strength steel is investigated by conducting fatigue experiments under corrosive condition and hydrogen induced condition, potentiodynamic polarization test, tensile test and surface analyses. Nb element is added to enhance the mechanical property of medium carbon steel. This element forms MX-type phases such as carbides and nitrides which are playing an important role in the grain refinement. The grain refinement is one of the effective way to improve mechanical property because both tensile strength and toughness can be improved at the same time. However, MX-type phase precipitates can be a susceptible site to localized corrosion in corrosive environment due to the potential difference between matrix and precipitate. The obtained results showed that Nb-added steel improved corrosion fatigue property by grain refinement. However, it is degraded for hydrogen-induced fatigue property due to Nb, Ti-inclusions acting as a stronger trap.

Effect of Ethanolamine Salts and Enhancers on the Percutaneous Absorption of Meloxicam from a Pressure Sensitive Adhesive Matrix

  • Ki, Han-Moe;Cheong, Hyun-Ah;Choi, Hoo-Kyun
    • Journal of Pharmaceutical Investigation
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    • v.37 no.3
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    • pp.173-177
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    • 2007
  • The purpose of this study was to investigate the effect of salt formation on the percutaneous absorption of meloxicam through hairless mouse skin from a pressure sensitive adhesive (PSA) matrix. In addition, the influences of enhancers on the permeation of meloxicam or meloxicam-ethanolamine (MX-EA) salts across the hairless mouse skin were evaluated using a flow-through diffusion cell system. The salt formation of meloxicam resulted in lower permeation rate than the parent drug. $Span^{(R)}$ 80 provided the highest enhancing effect for meloxicam and meloxicam monoethanolamine salt. The maximum amount of the drug that can be loaded without retarding permeation rate was different depending on the compound. No relationship was found between the fluxes of meloxicam or MX-EA salts from saturated solutions and those from PSA matrices containing the same enhancer.

Biological effect of recombinant IL-1$\beta$ on the expression of antiviral genes in the gill of rainbow trout, Oncorhynchus mykiss

  • Hyun, Do Jeong
    • Journal of fish pathology
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    • v.16 no.3
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    • pp.139-146
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    • 2003
  • We have investigated the biological effects of recombinant IL-1$\beta$ (rIL-1$\beta$) on the expression of antiviral genes such as Myxovirus-3 (MX-3) and Interferon regulating factor-1 (IRF-1), which are related to type I interferon. When ten micrograms of rIL-1$\beta$ were treated, we observed the stimulatory effect on the expression of these antiviral genes. Interestingly, at the early stage of stimulation, these genes were down-regulated and then up-regulated by the results obtained that the expressions of these genes were decreased at day 1 post-injection and gradually increased at day 3 post-injection. Thus, the stimulatory effect of rIL-1$\beta$ on the expression of MX-3 and IRF-3 gene might be an indirect stimulatory effect because significant up-regulation was delayed until day 3 post-injection.

The Survey Analysis on the Exterior Connection Facility Conditions of University Campuses for Handicapped Students (장애학생을 위한 대학캠퍼스 옥외매개시설의 실태에 관한 조사 분석)

  • Choi, Jang-Soon
    • Journal of the Korean Institute of Rural Architecture
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    • v.14 no.1
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    • pp.21-28
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    • 2012
  • Campus facilities were recently remodeled to provide the substantial learning rights of handicapped students in many campus to embody the dignity and value as man. So this study aims to identify the exterior connection facilities for handicapped students of S and D campuses. The summaries of this research are as follows. Installations of even crossing area(1.5mx1.5m) per 50m and even rest area(1.5mx1.5m) per 30m in walking or access ramp. Improving in accordance with exterior connection facility repairing master plan in S campus. Bringing down an angle degrees of the inclined walking or access ramp in D campus. Installation of exterior braille guide sign for blind students. All handicapped students must be guaranteed the same learning rights as normal men to remove obstacles as the upper mentioned imperfections in using exterior campus facilities.

11CrMoVNb 페라이트계 내열강의 크리프 파단 시간에 따른 미세조직의 변화

  • Lee, Gyu-Ho;Heo, Ju-Yeol;Jeong, U-Sang
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2011.05a
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    • pp.57.2-57.2
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    • 2011
  • MX 석출물 형성 원소인 V과 Nb을 첨가한 11Cr-1Mo-VNb 페라이트계 내열강의 각각의 시험 온도에서 파단 시간에 따른 미세조직의 변화를 연구하였다. 초기 조직은 템퍼드 마르텐사이트 조직을 갖고 있었으며, 고온 강도를 저하시키는 ${\delta}$-페라이트는 존재하지 않았다. 주 석출상은 $M_{23}C_6$와 MX로 확인되었다. 또한, 모든 크리프 파단재에서 응력을 받은 게이지 부분이 응력을 받지 않은 그립 부분보다 석출물 및 마르텐사이트 래스 폭의 성장이 가속되는 결과를 나타내었다. 이는 크리프 변형 중 응력 집중에 의해 래스 경계를 따라 전위가 집적되고, 이에 따른 용질원자의 확산 속도가 증가하여 석출물의 성장에 따른 래스 경계의 이동이 일어나 게이지 부분이 그립 부분보다 마르텐사이트 회복이 가속된 것으로 판단된다.

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Configuration of Mail Delivery System Based on Reinforcement Learning

  • Morishita, Soichiro;Hiraoka, Kazuyuki;Kobayashi, Hidetsune;Mishima, Taketoshi
    • Proceedings of the IEEK Conference
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    • 2002.07b
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    • pp.830-833
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    • 2002
  • To solve the internal security problem such as human error and bad faith, the automation of computer system management is significant. For this purpose, we focus attention in the automation of Mail Delivery Service. Today, requirement for reliable mail delivery system becomes larger and larger. However, existing systems are too strict about their configuration. Hence, we propose the method based on Reinforcement Learning (RL) to achieve proper MX record ordering. A measure on validity of the design of system, such as network topology number of servers and so on, is also obtained as side benefit. In order to verify the usability of the presented method, we did on a small model of mail delivery system. As a result, we show that RL is available for determination of the proper MX record ordering. Additionally, we suggest that it is also available for comparing validity of setting of MTA and the network design.

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The CG Binding of Multi-Threaded Process for CC-NUMA System (CC-NUMA 시스템을 위한 다중 스레드 프로세스의 CG 바인딩)

  • 김정녀;김해진;윤석한;이철훈
    • Proceedings of the Korean Information Science Society Conference
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    • 1999.10c
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    • pp.155-157
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    • 1999
  • 본 논문에서는 CC-NUMA 시스템인 고성능 멀티미디어 서버(MX Server)상에서 다중 스레드 프로세스의 CG(CPU Group) 바인딩 설계 및 구현 내용을 소개한다. 고성능 멀티미디어 서버의 컴퓨팅 서버용 운영체제인 COSMIX(cache COherent Shared Memory unIX)에서는 서버의 플랫폼에 알맞은 하드웨어 및 시스템 관련하여 CC-NUMA 시스템에 적합한 운영체제 기능을 설계하였다. 고성능 멀티미디어 서버에서는 데이터의 지역성을 고려하여 한 노드인 CG에 프로세스를 바인드 하는 기능이 있으나, 다중 스레드로 구성된 프로세스의 바인딩 기능은 없었다. Oracle8i와 같은 인터넷 DBMS에서는 하나의 프로세스내의 다중 스레드가 일정한 노드의 디스크를 점유하여 사용할 수 있으므로 이와 같은 다중 스레드의 프로세스를 해당 디스크가 있는 하나의 CG에 바인딩 하는 기능이 필요하다. 현재는 가용한 플랫폼이 없어서 MX Server 대신 PC 태스트베드인 CC-NUMA 시스템 시뮬레이션 환경에서 다중 스레드의 CG 바인딩 기능을 구현하고 그 시험을 완료하였다.

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