• Journal of agriculture & life science
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• v.46 no.5
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• pp.1-10
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• 2012

This study analyzed on the characteristics of vegetation structure, species composition and DBH class distribution in order to conservation and effective management for Taxus cuspidata community in Mt. Seorak, Mt. Balwang, Mt. Taebaek, and Mt. Odae. The vegetation in upper, subtree and shrub layer was consist of 11, 22, 33 species in Mt. Seorak, 15, 21, 33 species in Mt. Balwang, 10, 23, 36 species in Mt. Taebaek, and 14, 30, 32 species in Mt. Odae. As a result of importance value at all study sites, T. cuspidata and Abies nephrolepis in upper layer, T. cuspidata, A. nephrolepis and Acer komarovii in subtree layer, and Tripterygium regelii in shrub layer were high, respectively. Species diversity in upper and subtree layer at all study sited were ranged 0.834~1.234 and 1.125~1.329, respectively. According to the DBH class of major three species, T. cuspidata in Mt. Odae site showed a reverse J-shaped curve, which was estimated that T. cuspidata community of this site might be maintained continuously as a stable state.

• The Korean Journal of Blood Transfusion
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• v.29 no.3
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• pp.253-261
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• 2018

Background: A massive blood transfusion (MT) requires significant efforts by the Blood Bank. This study examined blood product use in MT and emergency O Rh Positive red cells (O RBCs) available directly for emergency patients from the Trauma Center in Ajou University Hospital. Methods: MT was defined as a transfusion of 10 or more RBCs within 24 hours. The extracted data for the total RBCs, fresh frozen plasma (FFP), platelets (PLTs, single donor platelets (SDP) and random platelet concentrates (PC)) issued from Blood Bank between March 2016 and November 2017 from Hospital Information System were reviewed. SDP was considered equivalent to 6 units of PC. Results: A total of 345 MTs, and 6233/53268 (11.7%) RBCs, 4717/19376 (24.3%) FFP, and 4473/94166 (4.8%) PLTs were used in MT (P<0.001). For the RBC products in MT and non-MT transfusions, 28.0% and 34.1% were group A; 27.1% and 26.0% were group B; 37.3% and 29.7% were group O, and 7.5% and 10.2% were group AB (P<0.001). The ratios of RBC:FFP:PLT use were 1:0.76:0.72 in MT and 1:0.31:1.91 in non-MT (P<0.001). A total of 461 O RBCs were used in 36.2% (125/345) of MT cases and the number of O RBCs transfused per patient ranged from 1 to 18. Conclusion: RBCs with the O blood group are most used for MT. Ongoing education of clinicians to minimize the overuse of emergency O RBCs in MT is required. A procedure to have thawed plasma readily available in MT appears to be of importance because FFP was used frequently in MT.

• Journal of Korean Neurosurgical Society
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• v.64 no.5
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• pp.693-704
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• 2021

Objective : Endovascular mechanical thrombectomy (MT) has been regarded as one of the standard treatments for acute ischemic stroke caused by large vessel occlusion. Despite the wide use of stent retrievers for MT, arterial intimal damage caused when deployed stent is pulled has been a certain disadvantage. We hypothesized that statin could protect and stabilize vessel damage after endovascular MT using a stent retriever. In this animal study, we observed the protective effects of the statins towards MT-induced vessel wall injury. Methods : Twenty-eight carotid arteries of fourteen rabbits were used in the experiments with MT using stent retriever. We divided the rabbits into four groups as follows : group 1, negative control; group 2, positive control; group 3, statin before MT; and group 4, statin after MT. After MT procedures, we harvested the carotid arteries and performed histomorphological and immunohistochemical analyses. Results : In histomorphological analysis with hematoxylin and eosin and Masson's trichrome stain, significant intimal thickening (p<0.05) was observed in the positive control (group 2), compared to in the negative control (group 1). Intimal thickening was improved in the statin-administered groups (groups 3 and 4 vs. group 2, p<0.05). We also observed that statin administration after MT (group 4) resulted in a more effective decrease in intimal thickness than statin administration before MT (group 3) (p<0.05). We performed immunohistochemical analysis with the antibodies for tumor necrosis factor-alpha (TNF-α), cluster of differentiation (CD)11b, and CD163. In contrast to the negative control (group 1), the stained percentage areas of all immunological markers were markedly increased in the positive control (group 2) (p<0.05). Based on statin administration, the percentage area of TNF-α staining was significantly reduced (p<0.05) in group 3, compared to the positive control group (group 2). However, significant differences were not observed for CD11b and CD163 staining. In group 4, no significant differences were observed for TNF-α, CD11b, and CD163 staining (p≥0.05). The differences in the percentage areas of the different markers between the statin-administered groups (groups 3 and 4) were also not revealed. Conclusion : We presented that statin administration before and after MT exerted protective effects towards vessel wall injury. The efficacy of statins was greater post-administration than pre-administration. Thus, statin administration in routine prescriptions in the peri-procedural period is strongly advised.

• Korean Journal of Plant Resources
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• v.10 no.4
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• pp.275-291
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• 1997

Floristic composition and medicinal plant resources were investigated in six regions, Mt. Sorak, Mt. Jumbong, Mt. Odae, Mt. Hwaak, Mt. Taebaek, and Mt. Bangtae, represent in Kangwon province. This study was conducted from December. 1995 to October, 1997. Vascular plants in investigated regions were composed of 118 families . 529 genera, 1,138 species, 7 subspecies, 223 varieties and 43 fromae, totaling 1,411 taxa. This taxa was correspond to 34.7% of Korean flora, 4,071 taxa (Lee, 1996b),and 73.8% of Kangwon province flora, 1,913 taxa (Kangwondo, 1996), respectively. Among them, medicinal plant resources was composed of 98 families, 238 genera, 337 species, 63. varieties, and 16 formae, totaling 416 taxa (29.5% of investigated 1.411 taxa). Medicinal plant resources in each regions were distributed ranging from 211(31.4%) to 285(33.1%) taxa.

• Journal of Electrochemical Science and Technology
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• v.3 no.2
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• pp.90-94
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• 2012

A simple and sensitive electrochemical sensor for simultaneous and quantitative detection of ranitidine (RT) and metronidazole (MT) was developed, based on a poly(thionine)-modified anodized glassy carbon electrode (PTH/GCE). The modified electrode showed the excellent electrocatalytic activity towards the reduction of both RT and MT in 0.1M phosphate buffer solution (PBS, pH 7.0). The peak-to-peak separations (${\Delta}E_p$) for the simultaneous detection of RT and MT between the two reduction waves in CV and DPV were increased significantly from ca. 100 mV at anodized GCE, to ca. 550 mV at the PTH/GCE. The reduction peak currents of RT and MT were linear over the range from 35 to $500{\mu}M$ in the presence of 200 and $150{\mu}M$ of RT and MT, respectively. The sensor showed the sensitivity of 0.58 and $0.78{\mu}A/cm^2/{\mu}M$ with the detection limits (S/N = 3) of 1.5 and $0.96{\mu}M$, respectively for RT and MT.

• Korean Journal of Microbiology
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• v.41 no.3
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• pp.195-200
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• 2005

Comamonas sp. strain DJ-12 is a bacterial isolate capable of degrading of 4-chlorobiphenyl (4CB) as a carbon and energy source. The degradation pathway was characterized as being conducted by consecutive reactions of the meta-degradation of 4CB, hydrolytic dechlorination of 4-chlorobenzoate (4CBA), hydroxylation of 4-hydroxybenzoate, and meta-degradation of protocatechuate to product TCA metabolites. The 6.8 kb fragment from the chromosomal DNA of Comamonas sp. strain DJ-12 included the genes encoding for the meta-degradation of PCA; the genes of protocatechuate 4,5-dioxygenase alpha and beta subunits (pmcA and pmcB), 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase (pmcC), 2-pyrone-4,6-dicarboxylate hydrolase (pmcD), 4-oxalomesaconate (OMA) hydratase(pmcE), 4-oxalocitramalate (OCM) aldolase (pmcF), and transporter gene (pmcT). They were organized in the order of pmcT-pmcE-pmcF-pmcD-pmcA-pmcB-pmcC. The amino acid sequences deduced from the nucleotide sequences of pmcABCDEFT genes from Comamonas sp. strain DJ-12 exhibited 94 to $98\%$ homologies with those of Comamonas testosteroni BR6020 and Pseudomonas ochraceae NGJ1, but only 52 to $74\%$ with homologies Sphingomonas paucimobilis SYK-6, Sphingomonas sp. LB126, and Arthrobacter keyseri 12B.

• Korean Journal of Environmental Biology
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• v.25 no.4
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• pp.289-296
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• 2007

Di-(ethyhexyl) phthalate (DEHP), commonly used as a plasticizer for manufacturing flexible vinyl products, has been the topic of extensive research, especially concerning endocrine disrupting properties. Metallothionein (MT) is a low molecular weight (6,000$\sim$7,000 Da), cysteine-rich (22$\sim$23%), metal-binding protein and is known to be induced by extrinsic factors such as chemical agents and stresses. Some of the known function of MT include detoxification of heavy metals and alkylating agents and neutralization of free radicals. Nonetheless, the definitive physiological function of MT are still unknown. This study was carried out to investigate the effects of DEHP on the ultrastructural changes and the expression of MT of the rat liver. The rats were orally intubated with either corn oil (experimental control) or 0.5 mg, 1.5 mg and 4.5 mg DEHP kg$^{-1}$ day$^{-1}$ in 0.5 mL of corn oil for 15 days before sacrificing and sampling. DEHP induced mild ultrastrctural changes of some cell organelles such as rough endoplasmic reticulum, mitochondria, lysosomes and peroxisomes in the rat liver treated with DEHP. In the respect of immunogold labelling and Western blotting, MT expression of the liver tissue was up-regulated by DEHP. In conclusion, DEHP has effects on the ultrastructures and hepatic function for MT expression in rat.

• Korean Journal of Plant Taxonomy
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• v.41 no.3
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• pp.287-297
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• 2011

The objective of this study was to discuss the characteristics of the moss flora of Mt. Deogyu located on the border of the Jeonbuk and Kyungnam provinces in Korea. A total of 21 field surveys were carried out at various sites in the mountain area from August 2007 to September 2008. All the collected materials were processed into voucher specimens and were currently deposited in the herbarium at Chonbuk National University (JNU). In this study, we collected and identified 158 moss taxa, which included 156 species, 1 subsp. and 1 var. of 96 genera and 37 families. Unconfirmed taxa in this study, but previously recorded, belonged to 25 taxa, which included 13 families, 19 genera and 25 species. In addition, 183 taxa were found on Mt. Dreogyu, which belonged to 37 families, 101 genera, 1 subsp. and 1 var. The habitat of each collection was examined and the classification system of Ignatov et al. (2006) was used. New vernacular names of 6 families and 11 genera were then determined. Six species, formerly thought be only in North Korea, were shown to be present on Mt. Deogyu, which included Bucklandiella laeta, Anomobryum filiforme var. concinnatum, Herzogiella turfacea, Brachythecium rutabulum, Eurhynchium angustirete and Campylidium hispidulum.

• 한국지구물리탐사학회:학술대회논문집
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• 2006.06a
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• pp.35-38
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• 2006

The polarized direction of MT field was analyzed using the MT dataset measured in the Korean Peninsula. The atmospherics above 1 Hz has a large dispersion of polarized direction, whereas the Schumann resonance near 8 Hz exhibits the predominant direction ranging from $N20^{\circ}W$ to NS. The electromagnetic field variations below 0.1 Hz, induced by magnetic pulsations, show a strongly polarized direction of nearly NS. It results from the regular pulsations since the regular pulsation fields, driven by Alfv.n's wave in the magnetosphere, has a worldwide predominant direction of NS. The MT field strongly polarized along NS direction causes the poorly behaved XY impedance.

• The Journal of Advanced Prosthodontics
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• v.9 no.3
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• pp.224-231
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• 2017

PURPOSE. This study was designed to evaluate the teeth and dental implants during dental maintenance therapy over 3 years in different conditions after periodontal and dental prosthetic treatment. MATERIALS AND METHODS. 166 patients received maintenance therapy. 59 patients were treated with 2% minocycline-HCl ointment as local drug delivery (LDD) (L group) and 107 patients were treated without LDD (NL group). Clinical data was collected in maintenance period for evaluation. Patients were classified into groups depending on the application of LDD with maintenance therapy, the type of dental treatment before maintenance period (Pre-Tx), the frequency (F-MT), and regularity (R-MT) of maintenance therapy. RESULTS. The numbers of lost teeth (N-teeth, P=.003) and newly placed dental implants (N-implants, P=.022) are significantly different according to Pre-Tx. F-MT among patients who received surgical dental treatment before maintenance period showed statistical differences in N-teeth (P=.041), but not in N-implants (P=.564). All of the patients in L group showed high F-MT (F-MT1). In NL group, there were no statistical differences in N-teeth or N-implants according to F-MT or R-MT. In F-MT1 group, application of LDD made N-teeth significantly different from both Pre-Tx groups while no significant difference could be found in N-implant. Independent t-test and one-way ANOVA were selected for statistical analysis. CONCLUSION. The regular maintenance therapy and LDD can be effective for teeth during maintenance period. It is not only pharmacological efficacy in decreasing bacterial species that makes LDD a useful adjunct. Application of LDD also motivates patients to take adequate check-ups in the aspects of both frequency and regularity.