• Journal of Korea Multimedia Society
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• v.19 no.8
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• pp.1236-1247
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• 2016

Recently, the level set has become a popular method in many research fields. The main reason is that it can be modified into many variants. One such case is our proposed method. We describe a contrast-enhancement method to segment the hippocampal region from the background. However, the hippocampus region has quite similar intensities to the neighboring pixel intensities. In addition, to handle the inhomogeneous intensities of the hippocampus, we used a bias correction before hippocampal segmentation. Thus, we developed a contrast-enhanced bias-corrected distance-regularized level set (CBDLS) to segment the hippocampus in magnetic resonance imaging (MRI). It shows better performance than the distance-regularized level set evolution (DLS) and bias-corrected distance-regularized level set (BDLS) methods in 33 MRI images of one normal patient. Segmentation after contrast enhancement and bias correction can be done more accurately than segmentation while not using a bias-correction method and without contrast enhancement.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.18 no.1
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• pp.105-125
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• 2024

Gliomas are the most common malignant brain tumor and cause the most deaths. Manual brain tumor segmentation is expensive, time-consuming, error-prone, and dependent on the radiologist's expertise and experience. Manual brain tumor segmentation outcomes by different radiologists for the same patient may differ. Thus, more robust, and dependable methods are needed. Medical imaging researchers produced numerous semi-automatic and fully automatic brain tumor segmentation algorithms using ML pipelines and accurate (handcrafted feature-based, etc.) or data-driven strategies. Current methods use CNN or handmade features such symmetry analysis, alignment-based features analysis, or textural qualities. CNN approaches provide unsupervised features, while manual features model domain knowledge. Cascaded algorithms may outperform feature-based or data-driven like CNN methods. A revolutionary cascaded strategy is presented that intelligently supplies CNN with past information from handmade feature-based ML algorithms. Each patient receives manual ground truth and four MRI modalities (T1, T1c, T2, and FLAIR). Handcrafted characteristics and deep learning are used to segment brain tumors in a Global Convolutional Neural Network (GCNN). The proposed GCNN architecture with two parallel CNNs, CSPathways CNN (CSPCNN) and MRI Pathways CNN (MRIPCNN), segmented BraTS brain tumors with high accuracy. The proposed model achieved a Dice score of 87% higher than the state of the art. This research could improve brain tumor segmentation, helping clinicians diagnose and treat patients.

• Journal of KIISE:Computing Practices and Letters
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• v.8 no.6
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• pp.705-716
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• 2002

This paper proposes a method which visualizes MRI head data in 3 dimensions with direct volume rendering. Though surface rendering is usually used for MRI data visualization, it has some limits of displaying little speckles because it loses the information of the speckles in the surfaces while acquiring the information. Direct volume rendering has ability of displaying little speckles, but it doesn't treat MRI data because of the data features of MRI. In this paper, we try to visualize MRI head data in 3 dimensions as follows. First, we separate the brain region from the head region of MRI head data, next increase the pixel level of the brain region, then combine the brain region with the increased pixel level and the head region without brain region, last visualizes the combined MRI head data with direct volume rendering. We segment the brain region from head region based on histogram threshold, morphology operations and snakes algorithm. The proposed segmentation method shows 91~95% similarity with a hand segmentation. The method rather clearly visualizes the organs of the head in 3 dimensions.

• Journal of Biosystems Engineering
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• v.27 no.3
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• pp.227-234
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• 2002

This study was conducted to nondestructively estimate the volumetric information of peach and pit and to visualize the 3D information of internal structure from magnetic resonance imaging(MRI) data. Bruker Biospec 7T spectrometer operating at a proton reosonant frequency of 300 MHz was used for acquisition of MRI data of peach. Image processing algorithms and visualization techniques were implemented by using MATLAB (Mathworks) and Visualization Toolkit(Kitware), respectively. Thresholding algorithm and Kohonen's self organizing map(SOM) were applied to MRI data fur region segmentation. Volumetric information were estimated from segemented images and compared to the actual measurements. The average prediction errors of peach and pit volumes were 4.5%, 26.1%, respectively for the thresholding algorithm. and were 2.1%, 19.9%. respectively for the SOM. Although we couldn't get the statistically meaningful results with the limited number of samples, the average prediction errors were lower when the region segmentation was done by SOM rather than thresholding. The 3D visualization techniques such as isosurface construction and volume rendering were successfully implemented, by which we could nondestructively obtain the useful information of internal structures of peach.

• Journal of Korea Society of Industrial Information Systems
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• v.8 no.4
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• pp.46-54
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• 2003

In this paper, we propose segmentation algorithm for MR brain images using the histogram of T1-weighted, T2-weighted and PD images. Segmentation algorithm is composed of 3 steps. The first step involves the extraction of cerebrum images by ram a cerebrum mask over three input images. In the second step, peak ranges are determined from the histogram of the cerebrum image. In the final step, cerebrum images are segmented using coarse to fine clustering technique. We compare the segmentation result and processing time according to peak ranges. Also compare with the other segmentation methods. The proposed algorithm achieved better segmentation results than the other methods.

• Korean Journal of Radiology
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• v.25 no.4
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• pp.363-373
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• 2024

Objective: To develop and evaluate a deep learning model for automated segmentation and detection of bone metastasis on spinal MRI. Materials and Methods: We included whole spine MRI scans of adult patients with bone metastasis: 662 MRI series from 302 patients (63.5 ± 11.5 years; male:female, 151:151) from three study centers obtained between January 2015 and August 2021 for training and internal testing (random split into 536 and 126 series, respectively) and 49 MRI series from 20 patients (65.9 ± 11.5 years; male:female, 11:9) from another center obtained between January 2018 and August 2020 for external testing. Three sagittal MRI sequences, including non-contrast T1-weighted image (T1), contrast-enhanced T1-weighted Dixon fat-only image (FO), and contrast-enhanced fat-suppressed T1-weighted image (CE), were used. Seven models trained using the 2D and 3D U-Nets were developed with different combinations (T1, FO, CE, T1 + FO, T1 + CE, FO + CE, and T1 + FO + CE). The segmentation performance was evaluated using Dice coefficient, pixel-wise recall, and pixel-wise precision. The detection performance was analyzed using per-lesion sensitivity and a free-response receiver operating characteristic curve. The performance of the model was compared with that of five radiologists using the external test set. Results: The 2D U-Net T1 + CE model exhibited superior segmentation performance in the external test compared to the other models, with a Dice coefficient of 0.699 and pixel-wise recall of 0.653. The T1 + CE model achieved per-lesion sensitivities of 0.828 (497/600) and 0.857 (150/175) for metastases in the internal and external tests, respectively. The radiologists demonstrated a mean per-lesion sensitivity of 0.746 and a mean per-lesion positive predictive value of 0.701 in the external test. Conclusion: The deep learning models proposed for automated segmentation and detection of bone metastases on spinal MRI demonstrated high diagnostic performance.

• Journal of Korea Multimedia Society
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• v.15 no.9
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• pp.1075-1085
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• 2012

In clinical research using medical images, the image segmentation is one of the most important processes. Especially, the hippocampal atrophy is helpful for the clinical Alzheimer diagnosis as a specific marker of the progress of Alzheimer. In order to measure hippocampus volume exactly, segmentation of the hippocampus is essential. However, the hippocampus has some features like relatively low contrast, low signal-to-noise ratio, discreted boundary in MRI images, and these features make it difficult to segment hippocampus. To solve this problem, firstly, We selected region of interest from an experiment image, subtracted a original image from the negative image of the original image, enhanced contrast, and applied anisotropic diffusion filtering and gaussian filtering as preprocessing. Finally, We performed an image segmentation using two level set methods. Through a variety of approaches for the validation of proposed hippocampus segmentation method, We confirmed that our proposed method improved the rate and accuracy of the segmentation. Consequently, the proposed method is suitable for segmentation of the area which has similar features with the hippocampus. We believe that our method has great potential if successfully combined with other research findings.

• Journal of radiological science and technology
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• v.27 no.3
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• pp.19-24
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• 2004

MRI imaging is one of the imaging techniques showing anatomical structures of human body for medical diagnosis, and has been researched in order to provide better quality of anatomical information. In this study, we propose a very useful method to extract an interest areas and how to diagnose necrolysis of femoral neck disease automatically. Regions of femoral neck is set using anatomical features and Hough transform and advantages of both region extension and histogram-based region segmentation method are combined for better region segmentation. As a result of the proposed method, good imaging quality was obtained for femoral neck with both normal and severe necrosis as well as for femoral neck in early stage of necrolysis.

• Proceedings of the IEEK Conference
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• 2002.07b
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• pp.802-805
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• 2002

In the three-dimensional domain image expressed with two-dimensional slice images, such as fMRI images and multi-slice CT images, we propose the three-dimensional domain automatic segmentation for the purpose of extracting region. In this paper, we segmented each domain from the fMRI images of the head of people and monkey. We used the neural network "Pulse-Coupled Neural Network" which is one of the models of visual cortex of the brain based on the knowledge from neurophysiology as the technique. By using this technique, we can segment the region without any learning. Then, we reported the result of division of each domain and extraction to the fMRI slice images of human's head using "three-dimensional Pulse-Coupled Neural Network" which is arranged and created the neuron in the shape of a three-dimensional lattice.

• Proceedings of the Korean Society of Computer Information Conference
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• 2022.07a
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• pp.223-224
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• 2022

본 논문에서는 축형 척추관절염으로 발전할 수 있는 천장관절염 환자들을 진단하기 위해 장골의 관심영역을 자동 생성할 수 있는 세그멘테이션 방법을 제안한다. 다양한 MRI 기기로부터 얻은 천장관절염 환자의 영상에서 장골의 GT(Ground Truth)를 생성하였으며, 대장 용종 검출을 위한 세그멘테이션 모델인 PraNet과 지역 특징 간의 표현 능력을 활용할 수 있는 Position Attention Module을 사용하여 유의미한 성능 향상을 보여주었다.