• The Transactions of the Korea Information Processing Society
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• v.7 no.2
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• pp.542-551
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• 2000

In this paper, a novel technique is presented for automatic brain region segmentation in single channel MR image data sets for 3D visualization and analysis. The method detects brain contours in 2D and 3D processing of four steps. The first and the second make a head mask and an initial brain mask by automatic thresholding using a curve fitting technique. The stage 3 reconstructs 3D volume of the initial brain mask by cubic interpolation and generates an intermediate brain mask using morphological operation and labeling of connected components. In the final step, the brain mask is refined by automatic thresholding using curve fitting. This algorithm is useful for fully automatic brain region segmentation of T1-weighted, T2-weighted, PD-weighted, SPGR MRI data sets without considering slice direction and covering a whole volume of a brain. In the experiments, the algorithm was applied to 20 sets of MR images and showed over 0.97 in comparison with manual drawing in similarity index.

• Journal of the Korea Society of Computer and Information
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• v.18 no.12
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• pp.21-26
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• 2013

In this paper, We are suggested methods of feature extraction in molecular images. The result of image transform DWT examination by suggested method, we are obtained as follows. 1-level and 2-levels of decomposition results showed the composition of the low frequency region. But, 3-level decomposition results did not appear in the data component is almost. Observed not with the naked eye is not, but the 3-level output data values of the results were decomposed. We are printed the horizontal and vertical directions of low-frequency region of the data, the high frequency region of the horizontal and vertical data, and diagonal high frequency region of the horizontal and vertical directions data. If the output data using molecular imaging and CT, PET, MR imaging will be compared with the data.

• International Journal of Computer Science & Network Security
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• v.21 no.2
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• pp.120-130
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• 2021

The spinal cord or CSF surgery is a very complex process. It requires continuous pre and post-surgery evaluation to have a better ability to diagnose the disease. To detect automatically the suspected areas of tumors and symptoms of CSF leakage during the development of the tumor inside of the brain. We propose a new method based on using computer software that generates statistical results through data gathered during surgeries and operations. We performed statistical computation and data collection through the Google Source for the UK National Cancer Database. The purpose of this study is to address the above problems related to the accuracy of missing hybrid KNN values and finding the distance of tumor in terms of brain cancer or CSF images. This research aims to create a framework that can classify the damaged area of cancer or tumors using high-dimensional image segmentation and Laplace transformation method. A high-dimensional image segmentation method is implemented by software modelling techniques with measures the width, percentage, and size of cells within the brain, as well as enhance the efficiency of the hybrid KNN algorithm and Laplace transformation make it deal the non-zero values in terms of missing values form with the using of Frobenius Matrix for deal the space into non-zero values. Our proposed algorithm takes the longest values of KNN (K = 1-100), which is successfully demonstrated in a 4-dimensional modulation method that monitors the lighting field that can be used in the field of light emission. Conclusion: This approach dramatically improves the efficiency of hybrid KNN method and the detection of tumor region using 4-D segmentation method. The simulation results verified the performance of the proposed method is improved by 92% sensitivity of 60% specificity and 70.50% accuracy respectively.

• Clinical Pain
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• v.19 no.2
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• pp.116-119
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• 2020

Cervical transforaminal epidural steroid injection (TFESI) is commonly performed to provide relief of pain caused by radiculopathy. Intra-arterial injection of particulate steroid or direct needle injury can lead to spinal artery embolism or thrombosis. Also there is a possibility of vascular spasm. To our knowledge, this is the first reported case of spinal cord infarction that occurred after TFESI with non-particulate steroid in Korea. A 47-year-old female patient underwent C7 TFESI at local pain clinic. Injected materials were dexamethasone and mepivacaine. Right after the intervention, she felt muscle weakness and decreased sensation. On physical examination, she had decreased sensation from C4 to T2 dermatome in light touch and pin-prick test. Proprioception and vibration were intact. The motor grades of upper extremities were grade 1. Cervical and thoracic spine MRI was checked. Diffusion-weighted image and apparent diffusion coefficient image showed long extension of spinal cord infarction from C2 to T1 level.

• The Korean Journal of Nuclear Medicine
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• v.36 no.3
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• pp.166-176
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• 2002

Purpose: The purpose of this study is to investigate the effects of visual activation and quantitative analysis of regional cerebral blood flow. Visual activation was known to increase regional cerebral blood flow in the visual cortex in occipital lobe. We evaluated that change in the distribution of $^{99m}Tc-HMPAO$ (Hexamethyl propylene amine oxime) to reflect in regional cerebral blood flow. Materials and Methods: The six volunteers were injected with 925 MBq (mean ages: 26.75 years, n=6, 3men, 3women) underwent MRI and $^{99m}Tc-HMPAO$ SPECT during a rest state with closed eyes and visual stimulated with 8 Hz LED. We delineate the legion of interest and calculated the mean count per voxel in each of the fifteen slices to quantitative analysis. The ROI to whole brain ratio and regional index was calculated pixel to pixel subtraction visual non-activation image from visual activation image and constructed brain map using a statistical parameter map (SPM99). Results: The mean regional cerebral blood flow was increased due to visual stimulation. The increase rate of the mean regional cerebral blood flow which of the activation region in primary visual cortex of occipital lobe was $32.50{\pm}5.67%$. The significant activation sites using a statistical parameter of brain constructed a rendering image and image fusion with SPECT and MRI. Conclusion: Visual activation was revealed significant increase through quantitative analysis in visual cortex. Activation region was certified in Talairach coordinate and primary visual cortex (Ba17),visual association area (Ba18,19) of Brodmann.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.34 no.3
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• pp.350-354
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• 2008

Mandibular chronic osteomyelitis with diffuse osteosclerosis is recognized as an intractable infectious disease. We emplyed decortication and intraarterial infusion of antibiotics in 6 cases. Decortication on the affected mandible was performed with retrocatherization to the superficial temporal artery of affected side under general anesthesia. Antibiotics, IPM/CS or FOMX was used through the artery for 4-11 days. In addition, we administered FOMX, PIPC intravenously for 8-17 days. CT and MRI were taken postoperatively. The postoperative follow-up period ranged from 1 year and 6 months to 2 years and 5 months. Postoperative MR showed that bone marrow signal was recovered to approximately normal in 4 cases. High signal area of bone marrow and osteosclerosis image remained in 2 cases, but showed improvement. The results were satisfactory without recurrence in all of 6 cases.

• The Journal of the Korea Contents Association
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• v.9 no.4
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• pp.247-253
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• 2009

PACS(Picture archiving communication system) is a system that enables medical images such as X -ray, CT, MRI, PET to be stored electronically viewed on computer screens so that doctors and other authorized people can access search the information as needed. But if they are not in hospital area for example on holiday or at night, that are not able to access the PACS system instantly. We have to solve this problem for more efficient patient care. So we try to suggest a method that use the PDA system that wireless LAN and CDMA cellular phone are equipped. This system may help to access easier to PACS system regardless of the location and can also attribute the development of telemedicne.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2009.11a
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• pp.99-102
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• 2009

본 연구에서는 실제 기증받은 시체를 이용하여 인체의 각 구조물을 실제 모습 그대로 3D 이미지화하는 과정에 대해 알아보았다. 인체의 구조물을 3D 로 이미지화하는 과정은 다음과 같다. 먼저 시체를 0.2mm 간격으로 절단하여 절단면의 사진을 찍은 후, 각 절단면의 사진에서 각각의 구조물을 구역화하여 색칠을 한 후, 구역화한 이미지에서 외곽선을 추출하여 벡터 이미지를 만든다. 이 외곽선을 1mm 간격으로 쌓아 올린 후 그 표면을 재구성하여 3D 이미지로 변환하는 과정으로 진행되었다. 3D 이미지의 제작은 가슴 부위에 한정하여 이루어졌다. 인체의 해부학적인 모형을 3D 이미지로 시각화함으로써 얻는 효과는 일반인을 대상으로 인체의 내부에 대한 시각적인 호기심을 충족시켜주고 의학 상식을 넓히는데 도움을 줄 수 있을 것 이다. 또한 의대생들을 비롯한 의학 전문가들에게는 생생한 해부학 강의용으로도 활용 가능하다. 향후 Haptic 시스템을 이용한 의료 실습 어플리케이션과 접목될 수도 있을것이고, fMRI 데이터를 비롯한 타 데이터와의 융합을 통해 시각화하여 서비스 할 수도 있다. 이처럼 인체의 3D 모형은 의료분야에서 광범위하게 활용될 수 있는 데이터로써 그 가치를 지닐 것이다.

• The Korean Journal of Cytopathology
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• v.15 no.1
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• pp.52-55
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• 2004

Secretory meningioma is a distinct subtype of meningioma. We describe the cytologic features of a secretory meningioma on squash preparations, in comparision with other cytologic mimickers. A 54-year-old woman presented with hearing loss, vertigo, tinnitus, and headache for seven years. A brain MRI study revealed a 4.5cm sized mass in the cerebellopontine angle, which showed homogenous signal intensity in T2-weighted image. The intraoperative squash smear showed some well-defined, thin rimmed intracytoplasmic inclusions, containing a finely granular eosinophilic core among less cohesive meningiomatous cells. Histologic sections revealed a meningothelial meningioma with scattered inclusions, with periodic acid-Schiff, carcinoembryonic antigen, and cytokeratin positivity. Identification of characteristic intracytoplasmic inclusions is helpful for diagnosing secretory meningiomas. On squash preparations, differential diagnoses included tumors with inclusions or cytoplasmic vacuolizations, such as metastatic mammary infiltrating ductal carcinoma, gastric adenocarcinoma, hepatocellular carcinoma, and clear cell ependymoma, oligodendroglioma, hemangioblastoma, chordoma, and other variants of meningiomas (clear cell, xanthomatous, microcytic, and chordoid variants). In addition, the possibilities of glioma with eosinophilic granular body, and metastatic tumors from mammary infiltrating ductal carcinoma, gastric adenocarcinoma, and hepatocellular carcinoma in meningioma should be considered.

• Korean Journal of Head & Neck Oncology
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• v.33 no.2
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• pp.49-53
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• 2017

Foregut cystic developmental malformations are rare developmental anomalies. It is important to diagnose the diseases and manage them properly because these cysts may generate feeding or respiratory difficulties depending on the size and location of the lesions. A newborn was referred for a congenital cervical swelling to our clinic on the second day of his life. Neck SONO and MRI showed an about 6cm sized cystic mass at left submandibular area. Aspirations and sclerotherapies were done repeatedly due to recurred cystic mass. Under the suspicious of cystic hygroma, the mass and submandibular gland were excised. Histologically, it was a benign cyst including gastrointestinal and bronchogenic mucosa and pancreatic tissue. Foregut cyst was suggested for the final diagnosis and the patient was discharged at 9 days after the operation without a complication. He has visited our out-patient department. Although several image studies have been introduced to find out foregut cyst, it is difficult to go through differential diagnosis because of similarity of other benign tumor. Further studies for early diagnosis of cervical foregut cyst are needed for preventing possible related problems.