• Journal of Korean Neurosurgical Society
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• v.37 no.6
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• pp.453-455
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• 2005

Two young women were brought to the Emergency room with generalized tonic and clonic seizures. Seizure developed seven and ten days after delivery respectively without the clinical signs of pre-eclampsia throughout the pregnancies. Magnetic resonance(MR) image of the brain showed characteristically symmetrical abnormal signals in the parietal and occipital regions. After several days of medical treatment, they were discharged without neurologic sequelae and follow-up MR images taken three months after discharge showed complete disappearance of the previous abnormal signals.

• Proceedings of the Optical Society of Korea Conference
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• 2001.02a
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• pp.270-271
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• 2001

안과 실명 질환의 가장 많은 부분을 차지하는 안구 망막의 실시간 3차원 계측기술은 아직 초보단계에 머물고 있다. 다른 장기나 조직에 비해 3차원계측기술이 늦어진 몇 가지 이유를 들면 다음과 같다. 첫째, 망막이 150$\mu$에서 400$\mu$의 얇은 막이어서 기존의 초음파(ultrasonography), CT(computerized tomography)나 MRI(magnetic resonance image)의 해상력으로는 영상화되지 않는다. 둘째로는 망막이 안구내의 뒤쪽에 위치하여 오직 동공을 통해서만 관찰 가능하여 3차원이 영상화가 어렵다. (중략)

• Journal of information and communication convergence engineering
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• v.2 no.3
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• pp.167-171
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• 2004

The evolution of modern imaging modalities, followed by the rapid development of computer technology has introduced many new features in the communication networks used in medical facilities. Since it is very important to keep patient's record accurately, the ability to exchange medical data securely over the communication network is essential for any medical information. In this paper, therefore, we introduce some problems which occur from digitizing medical images such as MRI (Magnetic Resonance Imaging), CT (Computed Tomography), CR(Computed Radiography), etc., and then we propose a authentication mechanism for medical image verification using secret watermark images.

• Proceedings of the Korean Society of Computer Information Conference
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• 2019.01a
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• pp.83-86
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• 2019

Histogram equalization is extensively used for image contrast enhancement in various applications due to its effectiveness and its modest functions. In image research, image enhancement is one of the most significant and arduous technique. The image enhancement aim is to improve the visual appearance of an image. Different kinds of images such as satellite images, medical images, aerial images are affected from noise and poor contrast. So it is important to remove the noise and improve the contrast of the image. Therefore, for this purpose, we apply a median filter on MR image as the median filter remove the noise and preserve the edges effectively. After applying median filter on MR image we have used intensity transformation function on the filtered image to increase the contrast of the image. Than applied the histogram equalization (HE) technique on the filtered image. The simple histogram equalization technique over enhances the brightness of the image due to which the important information can be lost. Therefore, adaptive histogram equalization (AHE) and contrast limited histogram equalization (CLAHE) techniques are used to enhance the image without losing any information.

• Journal of radiological science and technology
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• v.39 no.1
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• pp.51-57
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• 2016

Acoustic noise during magnetic resonance imaging (MRI) is the main source for patient discomfort. we report our preliminary experience with this technique in neuroimaging with regard to subjective and objective noise levels and image quality. 60 patients(29 males, 31 females, average age of 60.1) underwent routine brain MRI with 3.0 Tesla (MAGNETOM Tim Trio; Siemens, Germany) system and 12-channel head coil. Q-$T_2$ and $T_2$ sequence were performed. Measurement of sound pressure levels (SPL) and heart rate on Q-$T_2$ and $T_2$ was performed respectively. Quantitative analysis was carried out by measuring the SNR, CNR, and SIR values of Q-$T_2$, $T_2$ and a statistical analysis was performed using independent sample T-test. Qualitative analysis was evaluated by the eyes for the overall quality image of Q-$T_2$ and $T_2$. A 5-point evaluation scale was used, including excellent(5), good(4), fair(3), poor(2), and unacceptable(1). The average noise and peak noise decreased by $15dB_A$ and $10dB_A$ on $T_2$ and Q-$T_2$ test. Also, the average value of heartbeat rate was lower in Q-$T_2$ for 120 seconds in each test, but there was no statistical significance. The quantitative analysis showed that there was no significant difference between CNR and SIR, and there was a significant difference (p<0.05) as SNR had a lower average value on Q-$T_2$. According to the qualitative analysis, the overall quality image of 59 case $T_2$ and Q-$T_2$ was evaluated as excellent at 5 points, and 1 case was evaluated as good at 4 points due to a motion artifact. Q-$T_2$ is a promising technique for acoustic noise reduction and improved patient comfort.

• Radiation Oncology Journal
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• v.36 no.1
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• pp.11-16
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• 2018

Purpose: To investigate interobserver variation in target volume delineations for prostate cancer salvage radiotherapy using planning computed tomography (CT) versus combined planning CT and magnetic resonance imaging (MRI). Materials and Methods: Ten radiation oncologists independently delineated a target volume on the planning CT scans of five cases with different pathological status after radical prostatectomy. Two weeks later, this was repeated with the addition of planning MRI. The volumes obtained with CT only and combined CT and MRI were compared, and the effect of the addition of planning MRI on interobserver variability was assessed. Results: There were large differences in clinical target volume (CTV) delineated by each observer, regardless of the addition of planning MRI ($9.44-139.27cm^3$ in CT only and $7.77-122.83cm^3$ in CT plus MRI) and no significant differences in the mean and standard deviation of CTV. However, there were decreases in mean volume and standard deviation as a result of using the planning MRI. Conclusion: This study showed substantial interobserver variation in target volume delineation for salvage radiotherapy. The combination of planning MRI with CT tended to decrease the target volume and the variation.

• Journal of the Korean Society of Radiology
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• v.12 no.4
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• pp.475-480
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• 2018

In lower abdominal MRI scan, patients have been tested by physically contacting with the body array coil. In this study, we have designed the acrylic assistant equipment (ACR) which allows the contactless scan of the patient to the coil and evaluated the feasibility by comparing the acquired images with ACR to those obtained without ACR. We tested 10 cases (F: 5, m: 5) by using the Ingenia $3.0T^{TM}$ MR system and dStreamTM torso coil (Philips Healthcare, Netherlands). We implemented T1 AX TSE and eTHRIVE (GRE) techniques. The scanned images were quantitatively and qualitatively assessed. In qualitatively, the TSE shows 4.44 and 4.56 mean values with and without the ACR and 4.34 and 4.28 at the GRE, respectively. In quantitatively, the TSE shows 12.15 CNR, 17.95 SNR and 12.71 CNR, 18.96 SNR with and without the ACR. And GRE shows 17.72 CNR, 22.59 SNR and 18.26 CNR, 24.47 SNR with and without the ACR, respectively. We have designed and implemented the acrylic assistant equipment to lower abdominal patients. Our data indicate that it is possible to obtain similar image qualities to current lower abdominal MRI scan without the physical contact to the patient.

• The Korean Journal of Nuclear Medicine
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• v.37 no.4
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• pp.229-234
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• 2003

Purpose: Since the prognosis of measles encephalitis is poor, early diagnosis and proper management are very important to improve clinical outcomes. We compared Tc-99m ECD brain SPECT (SPECT) with MR imaging (MRI) for the detection of acute measles encephalitis. Materials and Methods: Eleven patients(M : F=4 : 7, age range 18 months-14 yrs) with acute measles encephalitis were enrolled in this studies. All of them underwent both MRI and SPECT. The results of SPECT were scored from 0 (normal) to 3 (most severe defect) according to perfusion state. We compared two image modalities for the detection of brain abnormality in acute measles encephalitis. Results: Seven of 11 patients (63.6%) revealed high signal intensity in the white matter on T2WI of MRI, on the other hand all patients (100%) showed hypoperfusion on SPECT. Severe perfusion deficits above score 2 were located with decreasing frequencies in the frontal lobe (81.8%), temporal lobe (72.7%), occipital lobe (27.3%), basal ganglia (27.3%), and parietal lobe (9.1%). Conclusion: We conclude that SPECT is more useful than MRI for the detection of brain involvement in patients with acute measles encephalitis.

• Journal of The Korean Association For Science Education
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• v.27 no.1
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• pp.93-104
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• 2007

The purpose of this study is to investigate brain activity both during the processing of a scientific hypothesis about biological phenomena and mental arithmetic using 3.0T fMRI at the KAIST. For this study, 16 healthy male subjects participated voluntarily. Each subject's functional brain images by performing a scientific hypothesis task and a mental arithmetic task for 684 seconds were measured. After the fMRI measuring, verbal reports were collected to ensure the reliability of brain image data. This data, which were found to be adequate based on the results of analyzing verbal reports, were all included in the statistical analysis. When the data were statistically analyzed using SPM2 software, the scientific hypothesis generating process was found to have independent brain network different from the mental arithmetic process. In the scientific hypothesis process, we can infer that there is the process of encoding semantic derived from the fusiform gyrus through question-situation analysis in the pre-frontal lobe. In the mental arithmetic process, the area combining pre-frontal and parietal lobes plays an important role, and the parietal lobe is considered to be involved in skillfulness. In addition, the scientific hypothesis process was found to be accompanied by scientific emotion. These results enabled the examination of the scientific hypothesis process from the cognitive neuroscience perspective, and may be used as basic materials for developing a learning program for scientific hypothesis generation. In addition, this program can be proposed as a model of scientific brain-based learning.

• Progress in Medical Physics
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• v.3 no.1
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• pp.63-69
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• 1992

Recently, stereotactic radiosurgery plan is required with the information of 3-D image and dose distribution. The purpose of this research is to develop 3-D radiosurgery planning system using personal computer. The procedure of this research is based on three steps. The first step is to input the image information of the patient obtained from CT or MR scan into personal computer through on-line or digitizer. The position and shape of target are also transferred into computer using Angio or CT localization. The second step is to compute dose distribution on image plane, which is transformed into stereotactic frame coordinate. and to optimize dose distribution through the selection of optimal treatment parameters. The third step is to display both isodose distribution and patient image simultaneously using superimpose technique. This prototype of radiosurgery planning system was applied recently for several clinical cases. It was shown that our planning system is fast, accurate and efficient while making it possible to handle various kinds of image modelities such as angio, CT and MRI. It is also possible to develop 3-D planning system in radiation therapy using beam's eye view or CT simulation in future.