• Title/Summary/Keyword: MPC

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Phospholipid Polymer, 2-Methacryloyloxyethyl Phosphorylcholine and Its Skin Barrier Function

  • LeeCho, Ae-Ri
    • Archives of Pharmacal Research
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    • v.27 no.11
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    • pp.1177-1182
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    • 2004
  • The effect of poly[2-methacryloyloxyethyl phosphorylcholine] (pMPC) on the skin permeation property was investigated by performing in vitro skin permeation study of a model drug, nicotinic acid (NA). Effect of pMPC polymer in donor solution on skin permeation rates was evaluated using side-by-side diffusion cells. Also, the structural alterations in the stratum corneum (SC), inter-lamellar bilayer (ILB) and dermis layers in pMPC-treated and -untreated skin sections were investigated with transmission electron microscopy (TEM). The permeation profile of NA without pMPC in donor solution showed biphasic mode: initial $1^{st} phase and 2^{nd}$ hydration phase. The sudden, more than 10-fold increase in flux from the initial steady state (43.5 $\mu g/cm^2$/hr) to the $2^{nd}$ hydration phase (457.3 $\mu g/cm^2$/hr) suggests the disruption of skin barrier function due to extensive hydration. The permeation profile of NA with 3% pMPC in the donor solution showed monophasic pattern: the steady state flux (10.9 $\mu g/cm^2$/hr) without abrupt increase of the flux. The degree of NA permeation rate decreased in a concentration-dependent manner of pMPC. TEM of skin equilibrated with water or 2% pMPC for 12 h showed that corneocytes are still cohesive and epidermis is tightly bound to dermis in 2% pMPC-treated skin, while wider separation between corneocytes and focal dilations in inter-cellular spaces were observed in water-treated skin. This result suggests that pMPC could protect the barrier property of the stratum corneum by preventing the disruption of ILB structure caused by extensive skin hydration during skin permeation study.

Development of the 120kW Class MPC Power Supply for DeNOx and DeSox System (120kW급 탈황탈질용 MPC전원장치 개발)

  • Kim, Soo-Hong;Kwon, Byung-Ki
    • Proceedings of the KIPE Conference
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    • 2009.11a
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    • pp.237-239
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    • 2009
  • This paper presents a new developed 160kV-120kW Class MPC (magnetic pulse compressor) power supply for DeNOx, DeSOx system. The circuit consists of N-series connected CCPS (capacitor charging power supply) and MPC Tank. The MPC power supply developed compared to the conventional LC resonant type has many advantage, it was verified reliability of a product by module, simulator and tank connection test. Now, the developed MPC power supply is installed POSCO sintering plant for DeSOx, DeNOx system.

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Obstacle Parameter Modeling for Model Predictive Control of the Unmanned Vehicle (무인자동차의 모델 예측제어를 위한 장애물 파라미터 모델링 기법)

  • Yeu, Jung-Yun;Kim, Woo-Hyun;Im, Jun-Hyuck;Lee, Dal-Ho;Jee, Gyu-In
    • Journal of Institute of Control, Robotics and Systems
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    • v.18 no.12
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    • pp.1132-1138
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    • 2012
  • The MPC (Model Predictive Control) is one of the techniques that can be used to control an unmanned vehicle. It predicts the future vehicle trajectory using the dynamic characteristic of the vehicle and generate the control value to track the reference path. If some obstacles are detected on the reference paths, the MPC can generate control value to avoid the obstacles imposing the inequality constraints on the MPC cost function. In this paper, we propose an obstacle modeling algorithm for MPC with inequality constraints for obstacle avoidance and a method to set selective constraint on the MPC for stable obstacle avoidance. Simulations with the field test data show successful obstacle avoidance and way point tracking performance.

MPC-based Active Steering Control using Multi-rate Kalman Filter for Autonomous Vehicle Systems with Vision (비젼 기반 자율주행을 위한 다중비율 예측기 설계와 모델예측 기반 능동조향 제어)

  • Kim, Bo-Ah;Lee, Young-Ok;Lee, Seung-Hi;Chung, Chung-Choo
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.61 no.5
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    • pp.735-743
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    • 2012
  • In this paper, we present model predictive control (MPC) applied to lane keeping system (LKS) based on a vision module. Due to a slow sampling rate of the vision system, the conventional LKS using single rate control may result in uncomfortable steering control rate in a high vehicle speed. By applying MPC using multi-rate Kalman filter to active steering control, the proposed MPC-based active steering control system prevents undesirable saturated steering control command. The effectiveness of the MPC is validated by simulations for the LKS equipped with a camera module having a slow sampling rate on the curved lane with the minimum radius of 250[m] at a vehicle speed of 30[m/s].

Research on improvement of water purification efficiency by porous concrete using bio-film (생물막을 이용한 다공성 콘크리트의 수질정화 효율 개선에 대한 연구)

  • Kim, Tae-Hoon;Li, Feng-Qi;Ahn, Tae-Woong;Choi, I-Song;Oh, Jong-Min
    • Journal of Environmental Impact Assessment
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    • v.20 no.6
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    • pp.815-821
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    • 2011
  • This study aims to estimate the biological decomposition capacity of MPC(Microorganism Porous-Concrete). MPC has specific surface area formed by inside pores, and bio compound was added to those pores to reduce pollutants loading. To evaluate the water purification capacity of MPC, we carried out the comparative studies using different media types [GPC(General Porous-concrete), CPC(Compound porous-concrete), LPC(Lightweight aggregate porous-concrete)] under the condition of CFSTR, and different retention times (30, 60 and 120 min). We also estimated the purification capacity of MPC under different concentrations of pollutant loadings. The MPC showed higher efficiency in water purification function than other conventional porous concretes with efficient decrease rates of SS, BOD, COD, and nutrient concentrations. In the comparison experiment for different retention times, MPC showed the highest removal efficiency for all tested pollutants in the longest retention time(120 min). In the long period test, the removal efficiencies of MPC concrete were high until 100 days after the set up of the operation, but began to decrease. Outflow flux was invariable compared with inflow flux so that extra detention time for media fouling such as back washing is not needed. But the results suggested that appropriate management is necessary for long-term operation of MPC. As the final outcome, MPC using bio organisms is considered to be efficient for stream water purification when they used as substrates for artificial river structure.

Effect of Phosphate Types on the Strength and pH of Magnesia-Phosphate Composites (마그네시아 인산염 복합체의 강도 및 pH에 대한 인산염 종류의 영향)

  • Lee, Kyung-Ho;Yang, Keun-Hyeok
    • Journal of the Korea Institute of Building Construction
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    • v.17 no.2
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    • pp.135-140
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    • 2017
  • As an elementary investigation to develop vegetation concrete with a relatively low pH value, magnesia-phosphate composites (MPC) were examined according to the phosphate types including Monoammonium, Monosodium, Monopotassium, Monocalcium, Diammonium, Disodium, Dipotassium, and Diacalcium phosphates. All of the MPC binders, the ratio of magnesia to phosphate was fixed to be 7:3. MPC mortars activated with Disodium, Dipotassium, and Diacalcium phosphates showed no compressive strength gain, even at age of 28 days. Meanwhile, MPC mortars with Monoammonium and Monosodium phosphates developed 28-day compressive strength of more than 34MPa, and showed a relatively low pH value below 9.8. Hence, Monoammonium and Monosodium phosphates have potentials as an activator for producing MPC-based vegetation concrete.

Human Papillomavirus Genotypes Associated with Mucopurulent Cervicitis and Cervical Cancer in Hangzhou, China

  • Shen, Xing-Hang;Liu, Shu-Hua
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.6
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    • pp.3603-3606
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    • 2013
  • Background: To investigate the infection status and predominant genotype distribution of human papillomavirus (HPV) infection among Chinese patients with mucopurulent cervicitis (MPC) or cervical cancer (CC) in Hangzhou. Methods: Initially, 217 cases of healthy cervix controls (n=50), acute MPC (n=89), and CC (n=78) were included; samples were collected between January 1, 2010, and January 30, 2013. Cervical specimens were screened for HPV using a nested polymerase chain reaction assay and DNA sequencing. Results: Overall prevalence of HPV infection was 16.7% in the control group, 51.9% in the MPC group, and 84.4% in the CC group. The predominant genotype detected in all 3 groups was the oncogenic variant HPV 16 (55.8%, 17.3%, and 6.3% in the CC, MPC and control specimens, respectively), HPV58 was the second most predominant HPV type in CC (9.1%), MPC (8.6%), and control group (4.2%). Most or all of the genotypes were oncogenic in the three groups. Conclusions: Infection with HPV was found to be prevalent among Chinese women with MPC or CC and oncogenic variants were in the majority. Therefore, peoples who suffered MPC with HPV DNA positive should be regularly followed-up, for prevention and early treatment of cervical cancer.

A Systematic Code Design for Reduction of the PAPR in OFDM (직교 주파수분할다중화에서 첨두전력 대 평균전력비 감소를 위한 체계적인 부호설계)

  • Kang Seog-Gen;Kim Jeong-Goo
    • Journal of Broadcast Engineering
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    • v.11 no.3 s.32
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    • pp.326-335
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    • 2006
  • Design criteria far a block code which guarantees minimized PAPR of the OFDM signals are proposed in this paper. Encoding procedure of the minimum PAPR codes (MPC) is composed of searching a seed codeword, circular shifting the register elements, and determining codeword inversion. It is shown that the PEP is invariant to the circular shift of register elements and codeword inversion. Based on such properties, systematic encoding rule for MPC is proposed. In addition proposed encoding rule can reduced greatly the size of look up table for MPC.

THE MODEL PREDICTIVE CONTROLLER FOR THE FEEDWATER AND LEVEL CONTROL OF A NUCLEAR STEAM GENERATOR

  • Lee, Yoon Joon;Oh, Seung Jin;Chun, Wongee;Kim, Nam Jin
    • Nuclear Engineering and Technology
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    • v.44 no.8
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    • pp.911-918
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    • 2012
  • Steam generator level control at low power is difficult due to its adverse thermal hydraulic properties, and is usually conducted by an operator. The basic model predictive control (MPC) is similar to the action of an operator in that the operator knows the desired reference trajectory for a finite period of time and takes the necessary control actions needed to ensure the desired trajectory. An MPC is based on a model; the performance as well as the efficiency of the MPC depends heavily on the exactness of the model. In this study, steam generator models that can describe in detail its thermal hydraulic behaviors, particularly at low power, are used in the MPC design. The design scope is divided into two parts. First, the MPC feedwater controller of the feedwater station is determined, and then the MPC level controller for the overall system is designed. Because the dynamic properties of a steam generator change with the power levels, a realistic situation is simulated by changing the transfer functions of the steam generator at every time step. The resulting MPC controller shows good performance.

Stability and Performance Investigations of Model Predictive Controlled Active-Front-End (AFE) Rectifiers for Energy Storage Systems

  • Akter, Md. Parvez;Mekhilef, Saad;Tan, Nadia Mei Lin;Akagi, Hirofumi
    • Journal of Power Electronics
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    • v.15 no.1
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    • pp.202-215
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    • 2015
  • This paper investigates the stability and performance of model predictive controlled active-front-end (AFE) rectifiers for energy storage systems, which has been increasingly applied in power distribution sectors and in renewable energy sources to ensure an uninterruptable power supply. The model predictive control (MPC) algorithm utilizes the discrete behavior of power converters to determine appropriate switching states by defining a cost function. The stability of the MPC algorithm is analyzed with the discrete z-domain response and the nonlinear simulation model. The results confirms that the control method of the active-front-end (AFE) rectifier is stable, and that is operates with an infinite gain margin and a very fast dynamic response. Moreover, the performance of the MPC controlled AFE rectifier is verified with a 3.0 kW experimental system. This shows that the MPC controlled AFE rectifier operates with a unity power factor, an acceptable THD (4.0 %) level for the input current and a very low DC voltage ripple. Finally, an efficiency comparison is performed between the MPC and the VOC-based PWM controllers for AFE rectifiers. This comparison demonstrates the effectiveness of the MPC controller.