• Title/Summary/Keyword: MP119

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Effect of Phyto-Extract Fermented Mixture (MP119) on the Sexual Functions and on the Toxicities of Cadmium (식물추출복합발효물(MP119)이 성기능에 미치는 영향 및 카드뮴 독성에 대한 효과)

  • Jang, Young-Sun;Jeong, Jong-Moon
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.38 no.12
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    • pp.1724-1731
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    • 2009
  • This study was aimed to investigate the effect of phyto-extract fermented mixture (MP119) on the male sexual functions. The MP119 was evaluated for anti-impotency and anti-hypertensive effects via ACE (angiotensin converting enzyme) or PDE (phosphodiesterase) inhibition assay. $IC_{50}$ values of MP119 against ACE and PDE were 241.3${\pm}$35.5 ppm and 372.2${\pm}$33.8 ppm, respectively. To investigate the effect of testosterone expression by MP119, we performed cell media test using mouse Leydig-derived TM3 cells. Production of testosterone in TM3 cell was increased by MP119. Also, NO (nitric oxide) production of HUVEC (human umbilical vein endothelial cell) was increased when MP119 was added to the cultures. Forty male ICR mice were divided into 4 groups. MP119 was orally intubated for 7 days to group 1 and 3, and same volume of vehicle to group 2 and 4 as controls. After that, group 3 and 4 were intraperitoneally injected cadmium chloride at a single dose of 2 mg/kg. On the 8th experimental day, weights of testis, epididymis and seminal vesicle, number of sperm, concentrations of serum testosterone and cGMP were determined. The number of sperm, the concentrations of testosterone and cGMP were significantly increased in two experimental groups (group 1, 3). These results suggest that MP119 enhanced the sexual function of male mice, and could protect the sexual organs from the cadmium chloride as one of the endocrine disrupters.

Environment-Usage-Performance Model on Participating Firms of Electronic Marketplace in Export Marketing (수출마케팅에서 무역e-Marketplace 참여기업의 환경-활용-성과모형에 관한 연구)

  • Chung, Chang-Kun;Kwak, Su-Young
    • International Commerce and Information Review
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    • v.9 no.1
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    • pp.119-148
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    • 2007
  • The purpose of this research is to study whether environments of participating firms of electronic marketplace(e-MP) have an influence on usage factors which are supplying from e-MP and usage factors affect usage performances. Based on the existing researches we found variables and executed a empirical study of environment-usage-performance model. Through this research we suggested useful factors for the performance of trade enterprises. Usage factors of e-MP will overcome geographical limitation and acquire new sales areas and simultaneously widen the relationships of global enterprises. Those firms could be accessible into global market promptly. To enhance usages of e-MP, service quality which can satisfy both buyer and seller at the same time should be strengtened. Finally, the usage of e-trade information should also heighten through usage factors.

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Naturally Derived Probiotic Supplementation Effects on Physiological Properties and Manure Gas Emission of Broiler Chickens

  • Hassan, Md R.;Ryu, Kyeong-Sun
    • Journal of agriculture & life science
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    • v.46 no.4
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    • pp.119-127
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    • 2012
  • To investigate the influence of multi-probiotic, fermented ginseng byproduct and fermented sulfone on the performance, intestinal microflora and immunity of broiler, a five weeks trial was conducted with 340, 1-d-old $Ross{\times}Ross$ broiler. All broilers were divided into five different groups having 68 birds in each treatment, and they were assigned as control, antibiotic avilamycin (AB), multi-probiotic (MP), fermented sulfone (FS) and fermented ginseng byproduct (FGB). Each artificial or naturally derived probiotic was inoculated 0.1% level with the basal diet, and all diets were provided to birds for five weeks. Weight gain and feed intake were measured weekly basis, and blood, spleen and feces were collectedand used for the physiological properties of broiler chickens. All performances and cholesterol profiles were not significantly differed but numerically lower level of neutral fat and LDL was found in multi-probiotics and FGB treatments respectively. The salmonella spp and E. coli numbers in the ileum were high in control in relation to those of other treatments and were significantly decreased in antibiotics treatments (p<0.05). In addition, Lactobacillus spp. showed significantly higher proliferation in MP as compared to that of others (p<0.05). Fecal ammonia and $CO_2$ gas emission was significantly decreased in MP, FGB and FS, respectively (p<0.05), but significantly increased proliferation of spleen was determined in MP group in comparison of other treatments (p<0.05). Therefore, the results indicates that multi-probiotics would be valuable feed additives to improve the salmonella, E. coli and Lactobacillus proliferation, and manure gas emission of broiler chickens, but further study related to the production of manure gas emission of MP is necessary.

Predictive model of fatigue crack detection in thick bridge steel structures with piezoelectric wafer active sensors

  • Gresil, M.;Yu, L.;Shen, Y.;Giurgiutiu, V.
    • Smart Structures and Systems
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    • v.12 no.2
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    • pp.97-119
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    • 2013
  • This paper presents numerical and experimental results on the use of guided waves for structural health monitoring (SHM) of crack growth during a fatigue test in a thick steel plate used for civil engineering application. Numerical simulation, analytical modeling, and experimental tests are used to prove that piezoelectric wafer active sensor (PWAS) can perform active SHM using guided wave pitch-catch method and passive SHM using acoustic emission (AE). AE simulation was performed with the multi-physic FEM (MP-FEM) approach. The MP-FEM approach permits that the output variables to be expressed directly in electric terms while the two-ways electromechanical conversion is done internally in the MP-FEM formulation. The AE event was simulated as a pulse of defined duration and amplitude. The electrical signal measured at a PWAS receiver was simulated. Experimental tests were performed with PWAS transducers acting as passive receivers of AE signals. An AE source was simulated using 0.5-mm pencil lead breaks. The PWAS transducers were able to pick up AE signal with good strength. Subsequently, PWAS transducers and traditional AE transducer were applied to a 12.7-mm CT specimen subjected to accelerated fatigue testing. Active sensing in pitch catch mode on the CT specimen was applied between the PWAS transducers pairs. Damage indexes were calculated and correlated with actual crack growth. The paper finishes with conclusions and suggestions for further work.

The Comparative Study on the wettability of the RGP lens multi-purpose solutions(MPSs) (RGP lens 다목적용액의 습윤성에 관한 비교 연구)

  • Park, Hyun-Ju;Goe, Eun-Kyung;Seo, Eun-Sun;Kim, Jai-Min;Lee, Ki-Young
    • Journal of Korean Ophthalmic Optics Society
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    • v.8 no.2
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    • pp.119-127
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    • 2003
  • We measured the effect of wettability of six MPSs for RGP lens. The used MPSs(multipurpose solutions) were OPTI-SOAK(ALCON), SOLO care hard(CIBA Vision), Total care(ALLERGAN), Simplicity(BOSTON). Wetting and Soaking Sol.(Bausch & Lomb) and Aquas-multi(Saehan). These MPSs keeps hydrophilic property of lens surface and increase the effect of cleaning or increase the effect of preservative effect. To compare with the effect of wettability we followed the way of contact angle measurement which was general way to measure wettability and compared lens which was conducted by each MPS made by different companies. As a control, 0.9% NaCl solution and artificial tears were used. The degree of the effect of wettability was decided by contact angle. It is hydrophilic property nearby $0^{\circ}$ of contact angle and it is closed by hydrophobic property as it increases. To compare with the effect of wettability we followed the way of contact angle measurement which was general way to measure wettability and compared lens which was conducted by each MPS made by different companies. As a control, 0.9% NaCl solution and artificial tears were used. The degree of the effect of wettability was decided by contact angle. It is hydrophilic property nearby $0^{\circ}$ of contact angle and it is closed by hydrophobic property as it increases. The results showed that every lens was nearby hydrophilic property within $25^{\circ}{\sim}36^{\circ}$. Also, it was differed by various factors. The surface tension showed various differences between 19.8 and 31.3(mN/m). In the viscosity, MPSs represented the highest viscosity between $4^{\circ}C$ and $20^{\circ}C$. It was much higher than compared with the viscosity of soft lens MPS. This experiment could be used to grasping the interaction between solutions used to MPS and the natural endowments of lens and to considering the relations of different factors effecting the wettability.

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A study on the effect that the green roof has on the performance of PV module (옥상녹화가 PV모듈 발전량에 미치는 영향 고찰)

  • Yoo, Dong-Cheol;Lee, Eung-Jik
    • Journal of the Korean Solar Energy Society
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    • v.32 no.2
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    • pp.113-119
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    • 2012
  • This study aims to examine the effect of the combined application of green roof and PV system on the PV efficiency by measuring the temperature and performance of PV module in order to reduce the temperature on the roof using roof planting system and determine the potential of efficient increase in solar-light power generation. In the experimental methodology, either monocrystalline or polycrystalline PV module was installed in green roof or non-green roof, and then the surface temperature of PV was measured by TR-71U thermometer and again the performance, module body temperature, and conversion efficiency were measured by MP-160, TC selector MI-540, and PV selector MI-520, respectively. As a result, the average body temperature of monocrystalline module was lower by $6.5^{\circ}C$ in green roof than in non-green roof; that of polycrystalline module was lower by $8.8^{\circ}C$ in green roof than in non-green roof. In the difference of generation, the electricity generation of monocrystalline module in green roof was 46.13W, but that of polycrystalline module was 68.82 W, which indicated that the latter produced 22.69W more than the former.

A Phenomenological Study on the Turnover Experience of Novice Nurses Working in General Hospital (종합병원근무 신규 간호사의 이직경험에 관한 현상학적 연구)

  • Im, Bo-Mi;Park, Jong-Min;Kim, Mi-Jin;Kim, Su-Yeon;Maeng, Jeong-Ho;Lee, Lu-Li;Kang, Kyung-Ah
    • Korean Journal of Occupational Health Nursing
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    • v.24 no.4
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    • pp.313-322
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    • 2015
  • Purpose: The purpose of this study was to identify novice nurses' experience of turnover. Methods: Data were collected from June to August, 2014 through in-depth interview and E-mail. Twelve novice nurses with turnover experiences were selected through snowball sampling method. All interviews were recorded with MP3 recorder and transcribed for analyzing by Van Kaam method of phenomenology. Results: The results were divided into 4 categories, 20 themes, and 119 formulated meaning related to turnover experience. These four categories were 'Excessively heavy working environment', 'Relationship problem', 'Physical/emotional withdrawal', and 'Realizing the absence of goal in job'. Conclusion: The result of this study will offer anticipatory information to understand of novice nurses' difficulties and to prevent their turnover. And these findings can be used for nursing administrators to design a turnover prevention program more effectively for nurses.

Studies on the Fermentative Production of Inosine-5′-monophosphate by Microorganisms (Part 1) Derivation of 5′-IMP Producing Mutants from Brevibacterium ammoniagenes (미생물에 의한 5′-이노신산의 생산에 관한 연구 (제1보) 5′-이노신산 생산균주의 분리)

  • Bae, Jong-Chan;Gong, Woon-Young;Son, Chung-Hong;Jang, Wook;Yoo, Ju-Hyun
    • Microbiology and Biotechnology Letters
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    • v.7 no.3
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    • pp.119-125
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    • 1979
  • As the first step of domestic developmint of the nucleic acid-related compounds, purine base required auxotrophs from Brevibacterium ammoniagenes ATCC 6872 were derived by the ultraviolet irradiation or the treatment of N-methyl-N'-nitro-N-nitroso guanidine (NTG), diethyl sulfate (DES), and ethylme-thyl sulfate (EMS). The optimum conditions of mutation by means of several mutagens were induced respectively. The yield of mutants was 0.083% by the ultraviolet irradiation, 0.67% by the NTG treatment, 1.1% by the DES treatment, and 0.45% by the EMS treatment. Six strains among 239 auxotrophs were screened out to accumulate 5'-lMP in the culture broth. Cry-stalline 5'-lMP was isolated from the culture broth of Brevifbacterium ammoniagenes adnine-guanine less mutant D-21530 by the use of anion exchange resin, Amberlite IRA-402, and it was identified physically and chemically as 5'-inosinic acid.

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Relationships between Milk Urea Nitrogen Concentration and Milk Components for Herd Management and Control in Gyeong-nam Dairy Cows (유우의 산유능력 검정성적과 MUN 농도와의 비교분석)

  • You, Yong-Sang;Kang, Dong-Joon;Kim, Cheol-Ho;Kim, Tae-Yung;Kang, Chung-Boo
    • Journal of Veterinary Clinics
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    • v.24 no.2
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    • pp.119-124
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    • 2007
  • Milk components analysis was carried out milk yield(MY), milk fat(MF), milk protein(MP), milk urea nitrogen(MUN), milk solid(MS), day of non-pregnant condition(DNPC), and days of primipara(DPRI) involved. Dairy farms were divided high, middle and low groups according to the standard records for milk components. Examination records were divided by farm, parity, year, season and month, the number of samples were 28,957. MUN concentration was below 12 mg and when the MPP was below 3.0%, the days of non-pregnant condition were $94{\pm}10.77$ days but concentration of MUN was under 12 mg and when MPP was above 3.2%, longer period of non-pregnant condtion of $181.3{\pm}9.25$ was noted. The days of gestation of the first calving cow was $495.9{\pm}9.04$ days when the concentration of MUN was below 12mg/dl and MPP was under 3.0%. If the concentration of MUN was 12 mg/dl and when the MPP was over 3.2%, the days of gestation were $511.0{\pm}8.36$ days. It was believed that the concentrations of MPP and MUN have significant effects on the days of non-pregnant condition and the days of gestation. Determination of MY, MF, MS, and MUN was Milkoscan $4,000{\sim}5,000$ Serier(FOSS Electric Co., Copenhagen, Denmark). MUN standard concentration was 12-18(mg/dl) similar to blood urea nitrogen(BUN). Mutual relationship of milk components(MF, SCC, MY, DNPC, MS) and MUN concentration was low in regression analysis.

Effects of Dietary Lipid Sources and Meal Frequency on Growing Performance and Lipid Metabolism in Rats (식이지방의 종류와 식이급여형태가 흰쥐의 성장 및 지방대사에 미치는 영향)

  • 이재준
    • Journal of Nutrition and Health
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    • v.26 no.2
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    • pp.119-130
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    • 1993
  • This study was carried out to investigate the effects of dietary lipid sources and meal frequency on growing performance and lipid metabolism in Sprague-Dawley strain male rats. The experiment was conducted in 4$\times$2 factorial arrangement with 4 sources of dietary lipid(palm oil, beef tallow, soybean oil and hydrogenated soyben oil) and 2 meal frequencies(ad-libitum or meal feeding). During the 4-week feeding period the rats were fed either ad-libitum (AL) or a single daily 3-hour meal (09 : 02-12 : 00) during the dark period. In vitro cultures were carried out to study the cholesterol synthetic activity in hte liver prepared from rats used in feeding trials. And in vitro cultures were also carried out to study the lipogenic and lipolytic activity in the liver and adipose tissues prepared from rats used in feeding trials. Present data indicated that body weight gain, feed intake and FER of AS(ad-libitum+soybean oil)and AHS(ad-libitum+hydrogenated soybean oil) group were significantly(p<0.05) higher than those of the other groups. It was found that the feed intake of MF group was much less than that of AL group. Total body weight gained by MF group was only 60% of AL group. Growing performance was not affected by dietary lipid sources. The cholesterol synthetic activity in liver tissues culture was markedly(p<0.05) increased in MF diets, especially in soybean oil group. The lipogenic activity in liver tissues culture of MP(meal feeding+palm oil) and MHS(meal feeding+hydrogenated soybean oil)group was significantly (p<0.05) higher than that of AP(ad-libitum+palm oil) group and AHS(ad-libitum+hydrogenated soybean oil) group(p<0.05). Rats fed ad-libitum+beef tallow and fed meal feeding+beef tallow showed significantly(p<0.05) higher lipogenesis than the other groups. It was apparent that the lipogenic activity in liver tissues culture was not affected by dietary lipid sources and meal frequency. Lipolytic activity in liver tissue culture was significantly(p<0.001)different with meal frequency; MF group was higher than AL group, but was not greatly affected by dietary lipid sources. In the in vitro studies with adipose tissue, MF diets increased the lipogenic activity and inhibited the lipolytic activity in adipocytes. The lipogenic activity in adipocytes was significantly (p<0.001) different with dietary lipid sources and found to be beef tallow group was the higherst, but the sources of lipid in the diet did not exert any effect on the lipolytic acitivity.

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