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Characterizations of Kefir Grains in Fermented Whey and Their Effects on Inflammatory Cytokine Modulation in Human Mast Cell-1 (HMC-1) (Kefir grain에 의한 유청발효액의 특성과 human mast cell-1 (HMC-1)에서 염증 cytokine 조절에 미치는 영향)

  • Son, Ji Yoon;Park, Young W.;Renchinkhand, Gereltuya;Han, Jung Pil;Bum, Jin Woo;Paik, Seung-Hee;Lee, Jo Yoon;Nam, Myoung Soo
    • Journal of Life Science
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    • v.26 no.6
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    • pp.689-697
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    • 2016
  • Kefir is an acidic-alcoholic fermented milk product originating from the Caucasian mountains. Kefir has long been known for its probiotic health benefits, including its immunomodulatory effects. The objectives of this study were to investigate the properties of a fermented whey product and to examine the effects of kefir grains on the in vitro immune-modulation of human mast cell-1 (HMC-1). The results showed that the whey fermented by kefir grains contained the maximum lactic acid bacteria and yeast for 16 hr by 1.83×108 and 6.5×105 CFU/ml, respectively, and lactose and whey proteins were partially hydrolyzed. The experimental whey fermented by kefir grains exhibited an in vitro anti-inflammatory effect on the HMC-1 line for 8, 16, and 24 hr, and this effect induced the expression of interleukin (IL)-4 as a pro-inflammatory cytokine, but not for 48 hr by RT-PCR in HMC-1 cells. In addition, the same phenomenon was observed for the expression of IL-8 as a pro-inflammatory cytokine by the kefir-fermented whey during the same periods of 8-48 hr under the same conditions. These cytokines resulted in the production of IL-4 at 20-25 ng in HMC-1 cells for 8, 16, and 24 hr, whereas 5 ng was produced for 48 hr by the fermented whey. In contrast, IL-8 was produced at 15-20 ng in HMC-1 cells during 4, 8, 16, and 24 hr, while 7 ng was produced at 48 hr. It was concluded that the whey fermented by kefir grains possesses a potential anti-inflammatory function, which could be used for an industrial application as an ingredient of functional foods and pharmaceutical products.

Water Landscape Displaying Techinques of Traditional Gardens between China and Korea - With Soswaewon and ZhuozhengYuan - (한.중 전통원림의 수경관 연출기법 비교 연구 - 소쇄원과 졸정원을 중심으로 -)

  • Lee, Hang Lyoul;Kim, Sun Rye
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.30 no.4
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    • pp.1-13
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    • 2012
  • Landscape Garden tradition of excellent examples of places that are focused on hydroponics management. South Korea and China, this thing was noticeable among them South Korea which emphasizes the natural contours of the natural streams in accordance with the basic idea to use examples that feature will do. Gardens in China by constructing a flat terrain also naturally expect to find examples of conscious ideas depending on the water and the mountains are characterized. These differences and similarities through the Gardens of the tradition of separating the two countries to build their Garden by site Soswaewon and Zolzengwon appear in the target hand is to identify the characteristics between the director. Research methods literature survey, field survey of the natural environment through the plantation, background history, the people who intend to study, to configure the ground water space, Jian, construction and management has been studied in hydroponics. As a result, Damyang-gun, Jeollanam-do, South Korea in the Garden of the Soswaewon(瀟灑園) organization with inner garden and outer garden of a small, but the scale of production to Yang San-Bo's 'eunilgwan' implement security based rock mooring takes the form of a linear channel and the water came down from riding pending to avoid artifacts gathered again took the form of streams flowing into that. Hutton was a rubble pile structure Jian. Building an Gwangpunggak, Jewoldang, as Daebongdae consist, respectively, depending on the purpose of the mooring was deployed by focusing. The other hand, is located at Suzhou, Jiangsu of China Zolzengwon(拙政園) flat terrain is located on. Largely divided eastern gardens, Central Gardens and the Gardens of the West was conducted by five thirds of the total area of Water accounted for. Pavilion the center of the pond, Seokgasan achieve a variety of landscapes and architectural features that are most of the Ming. The two countries, each region's natural environment and human environment, different, unique characteristics to each other in the implementation of a unique hydroponic Garden tube and ideological backgrounds, but especially the 'eunilgwan' and the terrain that is divided according to the conditions of this study, so fulfilling Garden was conducted.

Research on the Prototype Landscape of Former Donam SeoWon Located in YeonSan (연산 돈암서원(豚巖書院) 구지(舊址)의 원형경관 탐색)

  • Rho, Jae-Hyun;Choi, Jong-Hee;Shin, Sang-Sup;Lee, Won-Ho
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.30 no.4
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    • pp.14-22
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    • 2012
  • The position, size and landscape of the former Donam SeoWon as well as the physical organization of the old site, are studied to extract data for the enhancement of the authenticity of Donam SeoWon since its registration as a world heritage site. The results are as follows. The 'Donam(豚巖)' encaved rock, the tombstone of teacher Sagye(沙溪), Kimjipsadang(金集祠堂), the head of the Gwangsan Kim family, the Sagye stream in front of them, and the Gyeryong and Daedun mountains in the distance are united in the former Donam SeoWon as landscape elements that clearly show the characteristics of the former site, which was called 'Donam-Wollim(豚巖園林).' Moreover Yangseongdangsipyoung(養性堂十詠), adds the garden elements of a medical herb field, twins pond, a bamboo forest, a school, and a peach field. On this site, one can also engage in activities that are related to the land and are closely related to Neo-Confucianism such as fish watching, conferencing, visit in seclusion(訪隱), looking for monks, and overseeing farming. The former site facing east is assumed to have Sau(祠宇) - Eungdodang(凝道堂) - Ipdeokmum(入德門) - Sanangru(山仰樓: estimated). Jeonsacheong seems to have been located to the left of the Sau area, Yangseongdang, which contained upper and lower twin lotus ponds, on the right and was surrounded by various plants. As it has been used as a lecture hall for the past 250 years, the former Donam SeoWon, located 1.8km away from the current area, must be preserved, and the landscape should be formed to establish the authenticity of Donam SeoWon.

An Emergence of Tigers and Leopards in the Palace During the Joseon Period from the Environmental Historical Perspective (환경사 관점에서 본 조선시대 궁궐에 범과 표범의 출몰)

  • Hong, Hyoung-Soon
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.36 no.3
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    • pp.1-15
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    • 2018
  • This study aims to investigate an aspect of physical palace by reviewing the emergences of tigers and leopards in the palace in Hanyang from the environmental historical perspective. To do so, three topics in environmental history were reviewed including 'environment,' 'impact of human-beings on the environment,' and 'sense and attitude of human-beings on the environment' based on the historical records such as "'Wangjoshilok(王朝實錄)". The results of this study are as follows. First, It was confirmed that leopards and tigers were emerged not only in the palace but also near the City Wall of Hanyang from time to time in Joseon Dynasty. Moreover, tigers lived and propagated in the backyard. Second, This situation may be caused by the natural factors of palace in Hanyang including location, philosophy and technique of building, and so on. That means 'good location' placed by palace worked favorably not only for human-beings but also for the activities of tigers and leopards. Third, In addition to the locational environment, forest policies on the palace and capital may facilitate the emergences of leopards and tigers. With the managements of pine trees, prohibition of burials, prohibition of climbing, prohibition of mountain entrance, and so on, forests were developed in the mountainous territories, which might play a role of shelters or passages for the tigers and leopards. Fourth, It was confirmed that countermeasures on the emergences of tigers in the palace as well as the capital city were different by the kings. Out of these, Jeong-jo was highlighted to seek the realistic countermeasures with actual understanding on the emergences of tigers and leopards. Fifth, In summary, frequent emergences of tigers and leopards in the palace and capital city could be a practical evidence to show 'pro-naturalism' or 'eco-friendliness' of the palace in Joseon which was mentioned superficially, paradoxically speaking. Further studies with the related disciplines are required on the cultural or ecological history of the palace. In addition, it is considered to conduct more detailed scientific studies related to the trend of ecological changes in Joseon.

The Historical Geography of Land-Use and Agriculture Along the Lower Nam-River Floodplains (남강 하류 범람원의 토지이용과 농업형태 변화에 관한 연구)

  • Lee, Jeon;Son, Ill
    • Journal of the Korean association of regional geographers
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    • v.4 no.2
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    • pp.31-47
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    • 1998
  • This paper deals with the historical geography of land-use and agriculture along the Lower Nam-River floodplains. The reclamation process of the river floodplains, the cultivation methods on the reclaimed lands, and the land-use patterns and processes are investigated. The Nam River, one of the major tributaries of the Nakdong River, flows through the boundary between Ham-An and Eu-Ryong Guns. Larger floodplains are located in Ham-An Gun. The floodplains of Ham-An Gun have been surveyed intensively in this study. In South Korea, the alluvial plains, mostly located along the river valleys, have been reclaimed to provide fertile agricultural lands. Those along the upper river valleys were reclaimed before those along the lower river valleys. The flood-plains of Han-An Gun were reclaimed to be the largest agricultural lands of the Gun. The natural levees along the Lower Nam-River Valley were identified before the reclamation processes but now hardly identified. Relatively larger floodplains are located along the tributary streams of the Nam River. Often there are low-lying back swamps between the natural levees and the hills/mountains that rise above the floodplains. The back swamps, called 'natural bog lands' in this region, have been reduced in size and in number through reclamation for the purpose of agricultural and industrial land-uses. Now about ten 'natural bog lands' are found in the Ham-An floodplains, and some of them are being reclaimed for the industrial land-use. This study suggests the emergent need of conservation for the remaining 'natural bog lands' in terms of ecology. Seven agricultural fields of large size, originated from the Nam-River floodplains, are identified in this study: Kun(큰들), Chung-Am(정암들), Chang-chi(장지들), Baek-San(백산들), Ha-Ki(하기들), Gu-Hae(구혜들), and Chang-Po(장포들) fields. The Kun field was reclaimed during the Japanese control and the Gu-Hae, in the 1950s. All of those except the above two fields were reclaimed after the mid-1960s. The Nam-River Dam in Chinju, completed in 1969, contributed the reclamation processes along the Lower Nam-River floodplains. The rice acreage of the region has been reduced slowly since 1970 but the rice production of the region has been relatively stable (Table 4). Rice culture had been the most important agriculture on the reclaimed lands for decades before the greenhouse vegetable cultivation became more important in the 1980s. Among the vegetables cultivated in the greenhouse, the watermelon is the dominantly leading one. Watermelons are usually harvested two or three times in a year though it is possible to harvest four times in one year. The rotation of watermelons and rice is common in the region. It is known the physical conditions of the Nam-River floodplains in Ham-An Gun is the most suitable for watermelon cultivation in South Korea.

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Landscape of Erosional Basin in Korea -In case of land-use changes of hills- (우리 나라 침식분지의 경관 -구릉지의 토지이용 변화를 중심으로-)

  • Son, Myoung-Won
    • Journal of the Korean association of regional geographers
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    • v.6 no.2
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    • pp.83-96
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    • 2000
  • Erosional basins formed in middle and upper reaches of Korean great rivers have been main life space of local small and middle cities, but previous studies on erosional basins are widely apart from residents' life and are in shortage with the endeavor to elucidate the man and environment relationship. This paper analyzes the factors and the modes of land-use changes of hills in the erosional basin. In this paper four erosional basins with different geological conditions are selected to elucidate the effect of geological factor(Geochang: granite, Chogye: metamorphic rock, Angye: gravelly sedimentary rock, Maseong: limestone). And the distribution of land use on the transverse and longitudinal cross-section map of the hill is described. The landscape of erosional basin is consisted of surrounding mountains, hills, dissected valleys, and incoming river's floodplain. Dissected valleys and incoming river's floodplain were reclaimed early as paddy field and hills have been used as woodland up to recently. Residents have a new appreciation of hills as a productive hill out of a traditional holy space[mountain] by influence of capitalistic thought that 'natural environment is a sort of productive resource'. Population increase is the another pressure of hill reclamation. The modes of landscape changes due to natural conditions are as follow: (1) In Geochang basin with dense tectolineament spacing, the gentle part of hill is used as field, orchard and agricultural-industrial complex site and the steep part is as woodland. (2) Hills in Angye basin with sparse tectolineament spacing are relatively flat because of maintaining a part of original denudational surface, and are used as orchids, field, paddy fields and agricultural-industrial complex site. The dissection valleys between hills are gentle concave and are used as paddy fields. (3) Hills in Maseong basin are wide and flat, and are used as fields, orchards, and agricultural-industrial complex site. (4) Because hills in Chogye basin, a closed type, are weared by affluents and are narrow and short. Hills are used as woodland and wide dissected valleys are reclaimed as paddy fields.

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Reclassification of Winter Barley Cultivation Zones in Korea Based on Recent Evidences in Climate Change (최근의 기후변화를 고려한 가을보리 안전재배지대 구분)

  • Shim Kyo Moon;Lee Jeong Taek;Lee Yang Soo;Kim Gun Yeob
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.6 no.4
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    • pp.218-234
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    • 2004
  • Recent warm winters were evaluated for a possible shifting of the northern limit for winter barley cultivation in Korea. Therefore, safe zones for winter barley cultivation were reclassified based on the average and minimum January air temperature in recent years. The results are as follows: By analysis of mean values of January average air temperatures for 30 years (1971-2000), the northern limits for safe cultivation of hulled, naked, and malting barley were Ganghwa - Icheon - Chungju - Chunyang - Goseong, Cheonan - Geumsan - Mungyeong - Andong - Sokcho, and Gwangju - Jangheung - Sancheong - Pohang - Uljin lines, respectively. Meanwhile, based on the January average air temperature of 14 years (1987-2000) with warmer winters, the safe cultivation zone of winter barley shifted northward of the normal (1971-2000). So, the northern limits for hulled, naked, and malting barley were Pocheon - Chuncheon - Wonju - Yangpyeong - Chunyang, Ganghwa - Icheon - Chungju - Uiseong - Goseong, and Gunsan - Suncheon - Jinju - Miryang - Yeongdeok - Uljin lines, respectively. Winter barley cultivars with the strongest tolerance to low temperature can be grown up to the adjacent areas of Taebaek Mountains (that is, Inje, Hongcheon, Jecheon, and Taebaek areas). Based on January mean air temperatures of 10-year return period for 30 years (1971-2000), the northern limits for hulled and naked barley were Boryeong - Namwon - Geochang - Gumi - Goseong and Seocheon - Jeongeup - Hapcheon - Yeongdeok - Sokcho lines, respectively. It ~ppears that malting barley can be cultivated only at southern coastal areas (that is, Busan, Tongyeong, Yeosu, and Wando areas). On the other hand, based on the weather conditions of 14 years (1987-2000) with warmer winters, the northern limits for hulled, naked, and malting barley were Ganghwa - Icheon - Yeongju - Goseong, Seosan - Namwon - Mungyeong - Andong - Sokcho, and Gwangju - Jangheung - Sacheon - Ulsan - Uljin lines, respectively. The northern limit for winter barley cultivars including Olbori with the strongest tolerance to low temperature was the Ganghwa - Wonju - Chungju - Chunyang - Goseong line.

The Planting and Use of Landscaping Plants in Kangweon-Do (강원도내 조경식물의 배치과 이용)

  • 이기의;이우철;박봉우;조철길
    • Journal of the Korean Institute of Landscape Architecture
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    • v.15 no.3
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    • pp.33-50
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    • 1988
  • This study was executed to find out how to improve on the planting and use of the plants in Kangweon- Do by surveying the planting areas -gardens, parks, streets, schools, etc. - in five cities of this province, and to select available native plants by surveying the main mountains in this province. The results are as follows ; 1. The species number within surrey areas was 319 species. and the species of which planting frequency was very high were Hibiscus syriacus, Juniperus chinensis, Buxus microphylla v. koreana, etc.. 2. The species number of school trees and flowers of 202 schools in Kangweon-Do were 33 species, 32 species respectively. and the species of school trees and flowers that showed the highest preference were Juniperus chinensis, Forsythia koreana each. 3. The species number of flowers and trees designated in 22 City and Keun were 14 species, 7 species respectively, and the species of flowers and trees that presented the highest designation frequency were Rhododendron schlippenbachii, Ginkgo biloba each. 4. The street trees planted along the main streets in Kangweon-Do were 18 species and 84,939 individuals, and the ratio of Populus alba${\times}$glandulosa was the highest among occurrence individuals. 5, As for the composition ratios of life forms of plants within survey areas, the ratio of deciduous broad-leaved tree was the highest as about 56% and that of deciduous coniferous tree was the lowest as about 1.6%. The ratios of native species versus exotic were 43 : 57 6. Through these results, it was thought that the diversification of planing species, the selection of plants suitable to each space and the generalization of use of native species were needed. So 254 plants native to Kangweon-Do were presented to correspond to these requirements.

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A Semantic Interpretation of the Design Language in the ChwuiseokJeong Wonlim of Gochang - Focusing on the Alegory and Mimesis in 'Chwuiseok' and 'Chilseongam' - (취석정원림에 담긴 조형언어의 의미론적 해석 - '취석'과 '칠성암'에 담긴 알레고리와 미메시스를 중심으로 -)

  • Rho, Jae-Hyun;Lee, Hyun-Woo;Lee, Jung-Han
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.30 no.1
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    • pp.76-89
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    • 2012
  • This study aimed at carrying out a semantic interpretation of the core Design language that seemed to influence deeply in the creation of the ChwuiseokJeong wonlim of Gochang. Especially, this paper aimed at inferring how the spiritual culture of seclusion of the 16th century influenced the creation of the wonlim by understanding the metaphor and symbolism by grasping the transmission meaning and reception meaning of the creators and the people concerned with keywords like Eunil(隱逸: seclusion), Chwuiseok(醉石), and Chilseongam(七星巖). 'Building up a wall' was intentionally carried out in order to represent 'Seven Stars(The Big Dipper)' inside of the wonlim. This is a kind of two-dimensional 'enframement', and a result of active creation of a meaningful landscape. From Chilseongam that was created by assembling, we presumed that Kyung-Hee Kim, Nohgye(蘆溪), the creator showed the recognition and thoughts of astronomy as a Confucian scholar that the ChwuiseokJeong Wonlim where he secluded is the center of the universe. The interpretation of words in Nohgyezip, an anthology, showed that the articles and writtings of Nohgye, his decsendants, and the people of ChwuiseokJeong included alcohols, Chwuiseok, Yeon-Myung Do, and Yuli(栗里) where Do secluded; this means that Nohgye ranked himself with Do because Nohgye also lived in peace by drinking alcohols and enjoying nature like Do did. 'Drinking' was what expressed the mind of Nohgye who wanted to be free and have the joy of enjoying mountains, water, and their landscape like Do did. In other words, 'Drinking' is the symbol of freedom that makes him forget himself and equate himself with nature. These are the representation, imitation, and mimesis of respecting Yeon-Myung Do. As the alegory of 'speaking something with other things' suggested, it is possible to read 'Chwuiseok', came from the story of Yeon-Myung Do, in multiple ways; it superficially points out 'a rock on which he laid when he was drinking', but it also can be interpreted as 'an object' that made him forget his personal troubles. In addition, it means freewill protecting unselfish mind with the spiritual aberration of drinking, 'Chwui(醉)', mentally; also, it can be interpreted metaphorically and broadly as a tool that makes Nohgye reach to the state of nature by the satisfied mind of Yeon-Myung Do. 'Chwuiseok' was a design language that showed the situation of Nohgye by comparing his mind with the mind of Yeon-Myung Do from the Confucian point of view, and a kind of behavioral mimesis based on his respect to Do and 'aesthetic representation of objective reality.' It is not coincidental that this mimesis was shown in the engraved words on Chwuiseok and the creation of ChwuiseokJeong that has the same name with Chwuiseok in Korea and China.

Analysis of Relationship between Spatial Distribution of Land Use and Water Quality in Agricultural Reservoirs (토지이용의 공간적 분포와 농업용저수지 수질 간의 상관분석)

  • Lee, Sae-Bom;Yoon, Chun-Gyeong;Jung, Kwang-Wook;Jang, Jae-Ho;Jeon, Ji-Hong
    • Korean Journal of Ecology and Environment
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    • v.40 no.3
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    • pp.481-488
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    • 2007
  • This study covers the relationship between land use and water quality items. The kinds of land used in this study were almost agricultural areas with paddy fields and mountains. We set up zones at intervals of 200 m along 48 watersheds all over the country. The analysis showed high relationship between the water quality and the land use specially on the areas in the 400 m radius from the stream so that the areas needed to have strict managements. In the cases of residential area and upland, the positive correlation had a tendency to be lower when they were farther away from the stream. It depended on the increase of rainfall during July and August which affected on the water quality of reservoirs. The correlation analysis of paddy fields resulted in negative relationship, which indicated that paddy fields did not have negative effect on the quality of the stream. Through adequate irrigation and Management, paddy fields may be led to have positive effect on the quality of the reservoirs. In the case of forest, it also resulted in negative correlation so it was concerned as a positive factor which helped to improve water quality. Furthermore more than 00% of the land used in this study is comprised of forest so that it would have a positive effect on the reservoir management.