• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제35권2호
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• pp.74-82
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• 2009

In order to make successful oral cancer treatment, we need to understand about tumor biology and effective chemotherapeutic agents. To achieve these studies, it is necessary to develope a proper in-vivo model. Therefore the author will make try to develop more improved animal model of more applicable in various method of cancer study. In this study, the author induced in-vivo tumorigenesis in nude mice by $YD-10B_{mod}$ cell line used by YD-10B cell line originated from oral tongue squamous cell carcinoma and observed tumor formations and invasiveness of surrounding tissue, and found some results as follows : 1. The experimental group($YD-10B_{mod}$, subcutaneous injection) produced tumors 13 out of 15 mice, while the control group produced none of 5 mice. 2. The inoculation of $1{\times}10^6$cells/mouse produced tumors 3 out of 5 mice and inoculation of $1{\times}10^7$cells/mouse, $2{\times}10^7$cells/mouse produced tumors in every 5 mice. 3. In the histopathologic studies, the inoculation of $1{\times}10^6$cells/mouse group showed the characteristic features of well-differentiated squamous cell carcinoma and demarcated expansile growth, while the inoculation of $1{\times}10^7$cells/mouse, $2{\times}10^7$cells/mouse group showed the expansile growth with partial central necrosis and invasive growth to surrounding fat & connective tissue. These findings suggest that atopic xenograft of $YD-10B_{mod}$ cell line in nude mice has a improved productivity of tumors, produced tumors showed the characteristics feature of human tumor and invasive growth to surrounding tissue in histopathologic appearance. These atopic nude mouse model of tongue carcinoma might assist in studying oral cancer biology and effective choice of chemotherapeutic agents.

• 한국지반공학회지:지반
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• 제13권5호
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• pp.125-132
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• 1997

토석류는 다양한 크기의 흙 입자와 물이 고루 섞여 점성을 가진 유체처럼 하방향으로 이동한다는 사실이 관찰되었다. 이 관찰로부터 토석류를 비선행적인 점도를 가진 비뉴톤 유체처럼 거동하는 것으로 간주할 수 있다. 이 논문에서는 토석류의 레올로지적 특성을 규명하기 위해 산사태 현장에서 채취한 시료를 가지고 점도계를 사용하여 일련의 점도시험을 수행하였다. 그 결과, 토석류는 비뉴톤 유체 중 빙함 소성 모델로 거동한다는 사실이 밝혀졌다. 이 모델을 이용하면 토 석류의 이동을 예측할 수 있다.

• International Journal of Computer Science & Network Security
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• 제21권9호
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• pp.103-108
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• 2021

The emergence of new technologies and their implementation by different manufacturers of electronic devices are experiencing an ascending trend. Most of the time, these protocols are expected to reach a certain degree of maturity, and electronic equipment manufacturers use simplified communication standards and interfaces that have already reached maturity in terms of their development such as ModBUS, KNX or CAN. This paper proposes an IoT solution of the Smart Home type based on an Analysis and Prediction System. A data acquisition component was implemented and there was defined an algorithm for the analysis and prediction of actions based on the values collected from the data update component and the data logger records.

• 한국소음진동공학회논문집
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• 제13권6호
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• pp.452-459
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• 2003

The characteristics of fluid-elastic instability and effects of turbulent excitations for the KSNP steam generator tubes were investigated numerically. The information for the thermal-hydraulic data of the steam generator has been obtained by using the ATHOS3-MOD1 code and the flow-induced vibration(FIV) analysis has been conducted by using the PIAT(program for Integrity assessment of SG tube) code. The KSNP steam generator has the concentrated plugging zone at the vicinity of the stay cylinder inside the SG. To investigate the cause of the concentrated tube plugging zone, the FIV analysis has been performed for various column and row number of the steam generator tubes. From the results of FIV analysis the stability ratio due to the fluid-elastic instability and vibrational amplitude due to the turbulent excitation in the concentrated plugged zone have a trend of larger values than those of the outer concentrated tube Plugging zone.

• 대한원격탐사학회지
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• 제28권5호
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• pp.509-520
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• 2012

본 연구에서는 농경지의 면적 산정과 다양한 작물의 생산량 추정을 위해 많이 활용되고 있는 MODIS 영상과 기상자료를 이용하여 우리나라의 벼 수량을 추정해보고자 하였다. Terra와 Aqua 위성으로부터 얻어진 시계열 MODIS NDVI 자료를 구축하고 수량과의 상관성이 높은 시기를 선택하여 기상자료와 함께 다중회귀 모형 기반으로 우리나라 벼 수량을 추정하였다. 2002년부터 2010년까지 MODIS 위성 식생지수 NDVI와 기상자료(일조시간 및 일사량)를 이용하여 우리나라 벼 수량 추정을 위한 다중 회귀모형을 작성하였다. MODIS NDVI와 관측소 기상자료 1을 이용한 모형으로 2011년 쌀 수량 추정한 결과 $494.6kg\;10a^{-1}$로 통계청이 발표한 최종 수량과는 $1.1kg\;10a^{-1}$ 차이가 나는 것으로 나타났다. MODIS NDVI와 관측소 기상자료 2를 이용한 모형으로 2011년 쌀 수량 추정한 결과 $509.7kg\;10a^{-1}$로 통계청이 발표한 최종 수량과 $14.1kg\;10a^{-1}$ 차이가 나는 것으로 나타났다. 2002년부터 2011년까지의 우리나라 쌀 수량 분포도를 작성하였다.

• 한국수자원학회논문집
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• 제49권4호
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• pp.305-314
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• 2016

본 연구에서는 농업적 가뭄을 시, 공간적으로 파악하기 위하여 Terra의 MODIS 원격탐사 자료를 활용하여 가뭄의 정량적 평가를 실시하였다. 여러 가지 위성영상 중에서 식생 상태의 변화가 관찰되는 MOD13A3 영상을 통하여 NDVI (Normalized Difference Vegetation Index)와 EVI (Enhanced Vegetation Index)를 선정하였으며, 토지정보를 효율적으로 수집할 수 있는 MCD12Q1 영상의 Type1을 통하여 물, 도심지역 등을 제외한 식생부분만을 나타낼 수 있도록 토지피복분류를 하였다. 토지피복분류된 자료를 이용하여 NDVI와 EVI를 중권역별로 산정하여 나타낸 결과 계절적인 성향이 강하게 나타나 이를 보완하고자 EVI의 표준화 지수인 VSIA (Vegetation Stress Index Anomaly)를 우리나라의 극심한 가뭄해인 2001년에 대하여 중권역별로 산정하였다. 또한, 과거 우리나라의 농업가뭄 피해를 조사하였으며, 지상강우관측소의 자료를 통하여 SPI (Standardized Precipitation Index)를 중권역별로 산정하였다. SPI와 위성영상의 표준화 지수인 VSIA를 우리나라의 농업적 가뭄피해 연도와 비교하였으며, VISA의 시공간적 분석을 통해 한반도의 농업적 가뭄을 평가할 수 있는 활용성 및 적용 가능성을 검토하였다.

• 한국인터넷방송통신학회논문지
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• 제13권6호
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• pp.221-228
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• 2013

큰 반소수 n=pq의 소인수 p,q를 나눗셈 시행법으로 직접 찾는 것은 현실적으로 거의 불가능하다. 따라서 대부분의 소인수분해 알고리즘은$a^2{\equiv}b^2$ (mod n)의 제곱합동을 찾아 p=GCD(a-b, n), q=GCD(a+b, n)의 소인수를 찾는 간접 방법을 적용하고 있다. n = pq에 대해 p와 q를 선택한 영역은 $l(p)=l(q)=l(\sqrt{n})=0.5l(n)$의 [$10{\cdots}01$, $99{\cdots}9$] 범위에서 $\sqrt{n}$을 기준으로 $10{\cdots}00$ < p < $\sqrt{n}$과 $\sqrt{n}$ < q < $99{\cdots}9$에 존재한다는 사실만이 밝혀졌다. 본 논문은 n으로 부터 획득한 정보를 이용하여 p의 범위를 보다 축소시키는 방법을 제안한다. 제안 방법은 $n=n_{LR}+n_{RL}$, $l(n_{LR})=l(n_{RL})=l(\sqrt{n})$으로 분할하여 $p_{min}=n_{LR}$, $q_{min}=n_{RL}$로 설정하는 방법을 적용하였다. 본 논문에서 제안한 n의 정보로 p의 범위를 축소하는 방법은 $\sqrt{n}$의 정보로 p의 범위 축소 방법에 비해 최소 17.79%에서 최대 90.17%의 범위 축소 효과를 얻었다.

• 한국지반공학회지:지반
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• 제13권5호
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• pp.19-34
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• 1997

Classical earth pressure theories normally assume that ground condition remains uniform for considerable distance from the wall, and that the movement of the wall is enough to result in the development of an active pressure distribution. In the case of many low gravity walls in cut, constructed, for example, by using gabions or cribs, this is not commonly the case. In strong ground a steep temporary face will be excavated for reasons of economy, and a thin wedge of backfill will be placed behind the wall following its construetion. A designer then has the difficulty of selecting appropriate soil parameters and a reasonable method of calculating the earth pressure on the w리1. This paper starts by reviewing the existing solutions applicable to such geometry. A new silo and a wedge methods are developed for static and dynamic cases, and the results obtained from these are compared with two experimental results which more correctly mod el the geometry and strength of the wall, the fill, and the soil condition. Conclusions are drawn concerning both the magnitute and distribution of earth pressures to be supported by such walls.

• Macromolecular Research
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• 제13권1호
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• pp.54-61
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• 2005

We prepared temperature-sensitive liposomes (TS-liposomes) modified with a thermo sensitive polymer, such as poly(N-isopropylacrylamide) (PNIPAAm), to increase the degree of drug release from liposomes at the hyperthermic temperature. A PNIPAAm hydrogel containing TS-Iiposomes was also prepared to obtain a hydrogel complex at body temperature. In addition, a depot system for local drug delivery using the polymer hydrogel was developed to enhance therapeutic efficacy and prevent severe side effects in the whole body. The PNIPAAm-mod­ified TS-liposome was fixed into the PNIPAAm hydrogel having a high temperature-sensitivity. The release behavior of calcein, a model drug, from TS-liposomes in the PNIPAAm hydrogel was then initiated by external hyperthermia; the results indicated that sustained release as a function of temperature and time was caused by the thermosensitivity of the liposome surface and diffusion of the drug into the PNIPAAm hydrogel. Our results indicated that TS-liposomes in a PNIPAAm hydrogel represented a plausible system for local drug delivery.

• Restorative Dentistry and Endodontics
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• 제13권2호
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• pp.337-348
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• 1988

The purpose of this study was to examine the fracture strength and characteristics of teeth with MOD cavity preparation. Freshly extracted sound maxillary premolars were cleaned and stored in normal saline solution $37^{\circ}C$ for 72 hours before experiments. The roots of teeth were embedded in a self-curing resin, and the exposed crown were maintained in a vertical position by a modelling wax in a brass ring. The MOD cavities were prepared with No. 57 carbide bur under high speed to a depth of 2.0mm and a width of 2.0mm(Fig.1). All the prepared teeth specimens were divided into 7 groups according to the mode of cavity form and restorative materials (Table 1, 2): Group I, unpreapred, intact teeth as control Group II, prepared cavity without restoration Group III, prepared teeth restored with amalgam Group IV, prepared teeth restored with composite resin (P-10) Group V, prepared teeth with beveled enamel margins restored with composite resin (P-10) Group VI, prepared teeth restored with light-cured composite resin (P-30) Group VII, prepard teeth with beveled enamel margins restored with light-cured composite resin (P-30) After placement of restorations, all of the specimens were stored in water at $37^{\circ}C$ for 72 hours before testing. All of the specimens were tested on the Instron Universal Testing machine (No. 6025) in order to evaluate the strength of fracture. One metal ball 5.0mm in diameter contacting the specimens parallel to the occlusal surface was used to in this study (Fig. 1). The fracture characteristics of the specimens were examined with naked eye and in the scanning electron microscope (JSM-20). The results obtained from this study were as follows: 1. The mean fracture strength was the highest in group VI and that in group II was the lowest. 2. The progress of crack of teeth propagated into the pulp cavity. 3. In case of the group of the restored teeth, the crack occurred to be accompanied with cuspal fracture. 4. The crack of restored teeth was initiated along the pulpo-axial line angle of the cavity.