• Journal of Preventive Medicine and Public Health
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• v.55 no.1
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• pp.49-59
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• 2022

Objectives: Access to maternal and neonatal care services (MNCS) is an important goal of health policy in developing countries. In this study, we proposed a 3-level hierarchical location-allocation model to maximize the coverage of MNCS providers in Iran. Methods: First, the necessary criteria for designing an MNCS network were explored. Birth data, including gestational age and birth weight, were collected from the data bank of the Iranian Maternal and Neonatal Network national registry based on 3 service levels (I, II, and III). Vehicular travel times between the points of demand and MNCS providers were considered. Alternative MNCS were mapped in some cities to reduce access difficulties. Results: It was found that 130, 121, and 86 MNCS providers were needed to respond to level I, II, and III demands, respectively, in 373 cities. Service level III was not available in 39 cities within the determined travel time, which led to an increased average travel time of 173 minutes to the nearest MNCS provider. Conclusions: This study revealed inequalities in the distribution of MNCS providers. Management of the distribution of MNCS providers can be used to enhance spatial access to health services and reduce the risk of neonatal mortality and morbidity. This method may provide a sustainable healthcare solution at the policy and decision-making level for regional, or even universal, healthcare networks.

• Asian Journal of Innovation and Policy
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• v.7 no.1
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• pp.131-149
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• 2018

Multinational corporations (MNCs) leverage global locations for efficient production and sustained growth, and move significant foreign direct investments globally, particularly into emerging economies. MNCs also engage in entrepreneurial ecosystems of host countries for strategic benefits and impact the ecosystem as well. Of late, MNCs are increasingly entering into emerging economies like India through foreign direct investment (FDI) inflows and they are playing a vital role in start-up promotion in the entrepreneurial ecosystem. Therefore, we examine the role of MNCs and its impact on the entrepreneurial ecosystems in India by exploring a symbiotic relationship between MNCs and startups. We use a case-based method to ascertain and analyze specific benefits that emerge from such symbiotic relationships and draw implications for startups in India's technology entrepreneurial ecosystem.

• Journal of Information Technology Applications and Management
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• v.24 no.4
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• pp.13-24
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• 2017

This study aims to analyze which subsidiary configuration strategy is more effective under uncertainty especially technology base multinational corporations (henceforth MNCs). In previous studies real option theory scholars argue that high breadth subsidiary configuration is most effective strategy because that provides flexibility to MNCs global network. In this study I want unveil more various types of uncertainty such as technology and learning uncertainty which are more important for technology base firm and further more examine the effect of MNCs subsidiary configuration on firm R&D performance each uncertainty case. Empirical study is performed by negative binominal model based on Japanese 108 multinational corporations. The result shows that under technology uncertainty, high breadth subsidiary configuration is better for firm R&D performance but under learning uncertainty high depth subsidiary configuration is better. Thus, the effects of MNCs subsidiary configuration on firm value can differ by types of uncertainty.

• Asia-Pacific Journal of Business
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• v.14 no.1
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• pp.21-39
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• 2023

Purpose - The purpose of this study is to confirm that five different working positions show different Organizational Commitment (OC) and factors influencing OC levels in the Chinese MNCs. Design/methodology/approach - The study collected data of 326 employees in different positions in Chinese MNCs abroad and in domestic country. To test hypotheses, ANOVA analysis and linearity regression are used with SPSS 26 and AMOS 26 software on the collected data. Findings - Results shows that different working groups do not show significant difference of AC and CC level. However, there are significant difference of NC among the five groups in the Chinese MNCs. Employee's position and marital status are positively related to CC and NC. Tenure is positively related to AC. Research implications or Originality - Our research offers insight for further research direction on OC difference research. It provides implication for Chinese MNCs to consider more about strategies how to stimulate host country employee's normative commitment.

• Knowledge Management Research
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• v.12 no.1
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• pp.111-121
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• 2011

Multinational Corporations (MNCs) are establishing globally-distributed R&D centers around the world. Firms can overcome resource constraints and achieve superior innovative performance not only by using internal resources but also acquiring knowledge from oversea R&D centers. This paper explores the key factors that have been cited as significant influences on the ability to transfer knowledge, an important area of knowledge management of MNCs. Also, we identify the emerging outcomes in terms of R&D transfer and for the education, employment, and retention of knowledge works in MNCs. The result will be helpful for both MNC's managers and governments' decision makers with respect to R&D centers.

• International Area Studies Review
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• v.15 no.3
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• pp.605-625
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• 2011

Doing business in multiple countries, multinational corporations (MNCs) are warmly welcomed for additional choices of products and services available to local consumers. But in other markets, they are viewed negatively as a means of cultural imperialism even though MNCs do not change their strategies much. While the literature remains muted about such unpredictable consumer reactions, this study explores how consumers form their cultural imperialism perceptions on incoming MNCs using the consumer attitude theory.

• Journal of Korea Trade
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• v.25 no.1
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• pp.184-202
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• 2021

Purpose - This study empirically investigates the relationship between expatriate CEOs of multinational corporation (MNC) foreign subsidiaries and local philanthropy. Since corporate social responsibility (CSR) enables MNCs to achieve local legitimacy, this research argues that local philanthropy is a valuable strategic means for expatriate CEOs of foreign subsidiaries to secure local legitimacy. Design/methodology - To investigate our argument, we use a sample of 5,459 observations from 576 foreign subsidiaries of MNCs in Korea between 2002 and 2016. We conduct a random-effects panel Tobit regression with subsidiary CEO having foreign nationality as the independent variable and local philanthropy as the dependent variable. Findings - Our main findings are that expatriate CEOs of foreign subsidiaries are more actively engaged in local philanthropy. In addition, the positive relationship between expatriate CEOs and local philanthropy is weaker as their tenure increases. Originality/value - How expatriate CEOs overcome their weak local legitimacy as foreigners in a host country has remained unclear because existing studies mainly focused on the control and coordination aspects of staffing expatriates in CEO positions of foreign subsidiaries. This study broadens the literature on subsidiary CEO staffing and CSR activities of MNCs by identifying complementary relationships between expatriate CEOs and corporate philanthropy in the host country.

• Language and Information
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• v.17 no.2
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• pp.29-50
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• 2013

Multiple Nominative Constructions (MNCs) and Multiple Accusative Constructions (MACs) have been some of the hottest and interesting topics in Korean syntax. This paper took empirical approaches to these constructions and examined native speakers' grammaticality judgements of these constructions. Though there are lots of previous studies on these constructions, Ryu (2010, 2013a, 2013b, 2013c) recently tried to unify MNCs and MACs into Multiple Case Constructions (MCCs) and to classify them into 16 types based on the semantic relations. This paper includes experiments which were performed on these 16 different types. The experiments were designed following Johnson (2008); and the native speakers' intuition was measured with two scales, numerical estimates and line drawing, though the latter was adopted in the actual analyses. Through the experiment, the following facts were observed: (i) the grammaticality of the MCCs varies depending on their semantic relations, (ii) MNCs were more grammatical than MACs if both constructions occurred in similar environments, and (iii) the sentences in some MAC types had much lower grammaticality than those in the others, as Ryu (2013b, 2013c) mentioned.

• International Journal of Oral Biology
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• v.30 no.2
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• pp.47-57
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• 2005

Leptin, the product of the obese gene, is a circulating hormone secreted primarily from adipocytes. Several results suggest that leptin is important mediators of bone metabolism. The present study was undertaken to determine the effects of leptin on anti-osteoclastogenesis using murine precursors cultured on Ca-P coated plates and on the production of osteoprotegerin (OPG) in osteoblastic cells. Additionally, this study examined the possible involvement of prostaglandin $E_2\;(PGE_2)$/protein kinase C (PKC)-mediated signals on the effect of leptin on anti-osteoclastogenesis to various culture systems of osteoclast precursors. Osteoclast generation was determined by counting tartrate-resistant acid phosphatase positive [TRAP (+)] multinucleated cells (MNCs). Osteoclastic activity was determined by measuring area of resorption pits formed by osteoclasts on Ca-P coated plate. The number of 1,25-dihydroxycholecalciferol $(1,25[OH]_2D_3)$- or $PGE_2$-induced TRAP (+) MNCs in the mouse bone marrow cell culture decreased significantly after treatment with leptin. The number of receptor activator of NF-kB ligand (RANKL)-induced TRAP (+) MNCs in M-CSF dependent bone marrow macrophage (MDBM) cell or RAW264.7 cell culture decreased significantly with leptin treatment. Indomethacin inhibited osteoclast generation induced by $1,25[OH]_2D_3$ and dexamethasone, however, no significant differences were found in the leptin treated group when compared to the corresponding indomethacin group. Phorbol 12-myristate 13-acetate (PMA), a PKC activator, inhibited osteoclast generation induced by $1,25[OH]_2D_3$. The number of TRAP (+) MNCs decreased significantly with treatment by PMA at concentrations of 0.01 and $0.1{\mu}M$ in culture. Leptin inhibited PMA-mediated osteoclast generation. Isoquinoline-5-sulfonic 2-methyl-1-piperazide dihydrochloride (H7) had no effect on osteoclast generation induced by $1,25[OH]_2D_3$. Cell culture treatment with leptin resulted in no significant differences in osteoclast generation compared to the corresponding H7 group. Indomethacin showed no significant effect on TRAP (+) MNCs formation from the RAW264.7 cell line. PMA inhibited TRAP (+) MNCs formation induced by RANKL in the RAW264.7 cell culture. H7 had no effect on osteoclast generation from the RAW264.7 cell line. There was no difference compared with the corresponding control group after treatment with leptin. $1,25[OH]_2D_3$- or $PGE_2$-induced osteoclastic activity decreased significantly with leptin treatment at a concentration of 100 ng/ml in mouse bone marrow cell culture. Indomethacin, PMA, and H7 significantly inhibited osteoclastic activity induced by $1,25[OH]_2D_3$ in mouse bone marrow cell culture. No significant differences were found between the leptin treated group and the corresponding control group. The secretion of OPG, a substance known to inhibit osteoclast formation, was detected from the osteoblasts. Treatment by leptin resulted in significant increases in OPG secretion by osteoblastic cells. Taken these results, leptin may be an important regulatory cytokines within the bone marrow microenvironment.

• Management & Information Systems Review
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• v.32 no.3
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• pp.25-41
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• 2013

This study was designed to suggest the effective CSR strategies for MNCs operating in Chinese market. For this purpose, it compares the multi-years results for the evaluation on CSR activities of Multinational and Chinese firms. It also conducts questionnaire survey in an attempt at developing measures of Chinese publics' perception on the four dimensions of CSR defined by Research Center of Chinese Academy of Social Sciences - responsibility management, economic responsibility, social responsibility, and environmental responsibility. The findings of empirical analyses indicate that the CSR activities of MNCs much fall in all four dimensions compared with them of Chinese firms. Among four dimensions, MNCs have had bad evaluations especially on economic responsibility and social responsibility that are considered more important than the others to Chinese. Those findings imply that the MNCs has so far failed to implement effective CSR activities in China. In order to offset their liabilities of foreignness and compensate for their disadvantages in the lack of governmental supports, MNCs should intensify the CSR in economic and social responsibilities.