• Journal of Sasang Constitutional Medicine
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• v.23 no.3
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• pp.402-411
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• 2011

1. Objectives: This study is about three vascular dementia patients with disorientation, memory impairment and cognitive disorder. In this study, we evaluated the effects of Sasang constitutional treatment and suggested using the Mini Mental Status Examination - Korea (MMSE-K), Global Deterioration Scale (GDS). 2. Methods: These three patients were treated by Sasang constitutional herbal medications based on "Donguisusebowon". Acupuncture and west medications were limited as much as possible. We evaluated the symptoms through the Mini Mental Status Examination - Korea (MMSE-K), GDS (Global Deterioration Scale). 3. Results and Conclusions: Disorientation, memory impairment and cognitive disorder that were these three patients chief complaints were improved. This case study shows that Sasang constitutional herbal medications are an effective treatment for vascular dementia patients.

• PNF and Movement
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• v.10 no.3
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• pp.45-52
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• 2012

Purpose : This study examines the relationship between the Mini Mental State Examination-Korean Version(MMSE-K) and the Neuro-behavioral Cognitive Status Examination(NCSE) in Stroke Patients. Methods : We studied sixteen people with stroke(7 males, 9 females) who were admitted to occupational therapy a participants were tested with the MMSE-K, the NCSE. Results : Correlation between the NCSE and the MMSE-K was significant in p<.05, p<.01. The result was orientation r=.652, memory r=.514, attention r=.417, calculation r=.839, comprehension r=.676, repetition r=.960, naming r=.683, construction r=.961, judgement r=.616. Conclusion : The MMSE-K and the NCSE are valid and useful measurement tools evaluating cognitive function of persons with stroke in Korea.

• CELLMED
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• v.7 no.3
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• pp.13.1-13.10
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• 2017

Nutrition is one of the factors influencing cognitive functions. But, the role of nutrition on cognitive functions within the elderly is recognized to a lesser degree. The aim of this academic endeavor was to analyze the affiliation between nutritional status and cognitive functions of the elderly in Korea. 316 subjects, of 114 male and 201 female aged above 65 years, were gathered from university hospital clinics, Elderly Welfare Centers, and Health Welfare Centers located in the district of Seoul, Gyeonggi province, and Incheon in Korea. The cognitive function was tested by the Korean-Mini Mental State Examination (K-MMSE) questionnaire. Nutrition intake was assessed by a 24-hour recall, a food frequency questionnaire (FFQ). Nutrition adequacy and quality were assessed by the Nutrition Screening Initiative (NSI) checklist, the nutritional adequacy ratio (NAR), and the mean adequacy ratio (MAR). The elderly with normal cognitive function status displayed significantly higher levels of calcium, riboflavin, thiamin, folate, vitamin C, vitamin E, vitamin B6, phosphorous, potassium, iron, niacin, zinc, animal fat, animal protein, polyunsaturated fatty acids, total protein, vegetable oil, vegetable protein, fiber than levels of the elderly with moderate cognitive impairment. The K-MMSE score positively correlated with of high consumption of pork, white radish, sea mustard, tomato, tangerine, grape, apple, and ice cream, and K-MMSE was negatively associated with high intake of potato, anchovy, fish cake, and mushroom. The findings suggest that nutritional status is affiliated with cognitive function within the elderly of Korea. The consumption of variety of foods and nutrients ensures adequate cognitive function in the Korean elderly.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.4
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• pp.943-947
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• 2008

This study is designed to evaluate the effects of an oriental herbal medication namely Bojungikki-tang-gamibang on vascular dementia. The Clinical data was analyzed on a patient with vascular dementia due to deficiency of Spleen Gi, whose symptoms were dementia, Rt. side hemiparesis, insomnia, anorexia et al. The patient visited at the internal medicine department of Daegu Haany University affiliated Kumi Oriental Hospital on February 14, 2008 to March 28, 2008. The improvement of symptoms were checked by Mini Mental Status Examination-Korea(MMSE-K). After treatment, dementia, Rt. side hemiparesis, insomnia, anorexia got improved and MMSE-K score increased as well. This study suggests that Bojungikki-tang-gamibang is significantly effective in treatment of vascular dementia.

• PNF and Movement
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• v.12 no.4
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• pp.217-224
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• 2014

Purpose: The purpose of this study is to analyze the hand functions of elderly persons according to their cognitive status and age. Methods: A total of 65 persons voluntarily participated in the study. The subjects were divided into three groups: impairment cognitive group, normal cognitive group, adult group (persons in their twenties). Assessment of cognitive status was performed using a mini-mental state examination for Koreans (MMSE-K). Hand function was assessed using the Purdue pegboard test. The collected data were analyzed using a one-way ANOVA and Pearsonn Acorrelation. Results: There were significant differences in hand functions in the three groups. Post-hoc test results showed significant differences between each group. There were statistically significant differences in the correlation among hand functions, cognitive status, and age. The findings of this study suggest that hand functions have a positive correlation with cognitive status. However, a negative correlation was found between hand function and age. Conclusion: According to the study's results, hand functions are correlated with age and cognitive functions in elderly persons. This study suggests that hand rehabilitation with cognitive intervention increases hand functions in elderly persons.

• Journal of Korean Academy of Nursing
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• v.38 no.1
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• pp.1-10
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• 2008

Purpose: The purpose of this study was to examine cognitive functions, depression, and life satisfaction among the elderly receiving visiting nursing services. Methods: The subjects of this study consisted of 221 elderly individuals who were receiving visiting nursing services from a public health center located in Gyeonggi-do. The Mini-mental State Examination Korea version (MMSE-K), Geriatric Depression Scale-short form-Korea version (GDS-K), and Life Satisfaction Scale were utilized to determine cognitive functions, depression, and life satisfaction, Collected data was analyzed by the SPSS PC Win 12,0 program. Results: The prevalence of cognitive impairment (MMSE-K$\leq$24) was 86.4%, and the proportion of severe depression (GDS-K$\leq$10) was 22,6%, Older age, lower education, and low income were associated with cognitive impairment, and low education, no religion, and low income were associated with depression. Cognitive function negatively correlated with depression. Life satisfaction level was fairly low and was not associated with any variables. Conclusion: The high prevalence of cognitive impairment and low life satisfaction status were determined among low-income elderly who were registered at a visiting health care center. Thus, in the future at visiting health care services, efficient and various programs for the elderly should be tried, to improve cognitive functions and reduce depression. Additionally, consistent evaluation studies for those programs will be required.

• Journal of Korean Academy of Rural Health Nursing
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• v.1 no.1
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• pp.40-48
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• 2006

Purpose: This study was done to identify the experience of stress and burn-out in caregivers of patients with senile dementia. Method: To evaluate the degree of stress and burn-out in caregivers of patients with senile dementia, 64 caregivers and matched to 64 patients with senile dementia at a Primary Health Care Post in South Kyung Sung Province were selected. The study was carried out from March 6 to March 30, 2001. Data on the degree of dementia in the patients was measured by the MMSE-K (Mini-Mental State Examination-Korea) and caregiver characteristics such as, sex, age, marital status, educational level, job, socioeconomic status, religion, number in family, relationship with patient, duration of care, and chronic disease in caregiver were collected by direct interview with a questionnaire. Results: Of 64 patients with senile dementia, 15.6% were classified as mild dementia (MMSE score 20-24) and 84.4%, as severe dementia. There were no significant characteristics of caregivers associated with the degree of stress and burn-out experience. The degree of burn-out in these caregivers of patients with severe dementia (mean value 94.3) was significantly higher than the 81.4 for those caring for patients with mild dementia (p<0.05). However, the degree of stress was not significantly related with the degree of dementia. The proportion experiencing severe burn-out (above score 4) was 54.7% in the physical domain, 90.6% in the emotional domain, and 73.4% in psychiatric domain, respectively. Conclusion: The above findings suggest that the degree of stress and burn-out experienced by caregivers of patients with senile dementia are high. Also the degree of burn-out experienced by in caregivers of patients with severe dementia was higher than for those caring for patients with mild dementia.

• The Journal of Internal Korean Medicine
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• v.21 no.2
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• pp.193-201
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• 2000

Objective : In western medicine, many medication therapies and non-medication therapies have been treated for dementia. But these methods did no more than symptomatic therapies, not basic treatment, which just can better subordinate symptoms. In fact, care or control became the very point of treatment of dementia. So, to try to find oriental medical treatments for Dementia, a clinical analysis was carried out for 84 patients who were diagnosed as Dementia through MMSE-K and treated in Dong-shin Oriental Medicine Kwangju Hospital and Karitaas Sanatorium from 10. Jan. 1998 to 20. May. 2000. Methods : Regardless of patterns of Dementia, the basic treatment(本治) is to supplement encephalon deficiency(腦髓不足). And the external treatment(標治) must be accompanied by through diagnosis according to symptoms(辨證). All patients were given Yukmi-jihwanghwan gami and acupuncture treatment. Results : Dementia of cerebral vascular type shows a high distribution(51 patients, 60.7%). Women also are distributed more widely(62명, 73.8%). In Age distribition, 70-79 years-32 patients(38.1%), over 80 years-21 patients(25%), 60-69 years-17 patients(20.2%), 50-59 years-13 patients(15.5%) and under 49 years-1 patient(1.2%). From this, Dementia occurs well over 60 years and the rate of occurrence of Dementia is high as people grow older. In past history of people with Dementia, hypertension is associated much(50 patients, 64.1%). Distribution of mental state by MMSE-K examination declined in orientaion, mathmatical faculty, memory faculty and composition faculty. In therapeutic effect by treatment duration, 14 patients(93.3%) out of 15 in sanatorium show a significant effect. And 52 patients(75.4%) out of 69 in the hospital show the same result. Especially, 11 patients with Alzheimer type in sanatorium showed an good effect when treated over 4 months. 40 patients(83.3%) with cerebral vascular type out of 48 in the hospital showed the stage of betterment. Conclusions : The basic treatment(本治) for Dementia is to supplement encephalon deficiency(腦髓不足). For promoting encephalon through supplementing kindney(補腎健腦), All patients were given Yukmi-jihwanghwan gami. And the external treatment(標治) through diagnosis according to symptoms(辨證) were be accompanied by. The result is quite effective. We consider there must be more research based on this study.

• Journal of agricultural medicine and community health
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• v.24 no.2
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• pp.291-299
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• 1999

This study was conducted to evaluate the health status including mainly cognitive function and activities of daily living of institutional elderly in a rural area. We studied 466 subjects dwelling in ten institutions at Chonnam province, Korea. The participants consist of 148 males(31.8%) and 318 females(68.2%). We collected the information of socioeconomic state, mini-mental state examination(MMSE), activities of daily living(ADL), instrumental activities of daily living(IADL), and Dartmouth Primary Care Cooperative Information Project(COOP) chart. The results were followed: 1. Severe cognitive function impairment was appeared in 45 males(30.4%) and 115 females(36.2%). 2. The percentage of fully independent in the six ADL items was 50.0% of males and 42.8% of females, but 31.1% of males and 26.1% of females were fully dependent. 3. Males had more impairment in mode of transportation among IADL, but females had most impairment in laundry. 4. Observing health status by COOP chart, both had more grade in feeling and social activity than physical fitness.

• Korean Journal of Biological Psychiatry
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• v.14 no.3
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• pp.184-193
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• 2007

Objectives:There is increasing evidence that the cerebellum plays an important role in cognition and psychiatric symptoms as well as motor coordination. The concept of cognitive dysmetria has been making cerebellar function in schizophrenia the focus of current studies. In other words, disruption in the corticocerebellum-thalamic -cortical circuit could lead to disordered cognition and clinical symptoms of schizophrenia. The purposes of this study were to determine cerebellar dysfunction in male schizophrenic patients semiquantitatively with ICARS and to investigate the clinical and cognitive correlates of ICARS in patients. Methods:We compared the scores of cerebellar neurologic sign using ICARS in 47 male patients with a DSM-IV-TR diagnosis of schizophrenia with 30 gender and age-matched healthy control subjects. The semiquantitative 100-point ICARS consists of 19 items divided into 4 unequally weighted subscores:posture and gait disturbances, kinetic functions, speech disorders and oculomotor disorders. All subjects were also assessed with cognitive function test. Cognitive functions were evaluated by Korean-Mini Mental Status Examination (K-MMSE), Verbal fluency test, and Clock drawing test. The patients were administered Korea version of Positive and Negative Symptom Scale(K-PANSS) to assess the symptom severity. Results:Schizophrenic patients had significantly higher scores on the ICARS than control subjects with posture and gait disturbances, kinetic functions, and oculomotor disorders. They also showed more significant impairments in cognitive function tests than control subjects. There was a significant correlation between ICARS and negative symptoms of patients. In cognitive function test, Clock drawing test was significantly associated with negative symptoms. In addition, Clock drawing test was negatively correlated with the total score of ICARS. Conclusion:In this study, we confirmed that schizophrenic patients have significant impairments in cognitive and cerebellar function, and that those were related with negative symptoms of schizophrenic patients. These results support a role of the cerebellum in schizophrenia. It is meaningful that we used a structured, and reliable procedure for rating neurological soft signs, ICARS. We hope that future prospective studies using a similar design help that rate of neurological sign should have been visible with the progression of illness.