• Journal of radiological science and technology
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• v.39 no.4
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• pp.595-600
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• 2016

The diagnostic multileaf collimator(MLC) was designed for patient dose reduction in diagnostic radiography We used monte carlo simulation code (MCNPX, LANL, USA) to evaluate efficiency of shielding material for making diagnostic MLC as preliminary study. The diagnostic radiography unit was designed using SRS-78 program according to tube voltage (80,100,120 kVp) and acquired energy spectrums. The shielding material was SKD11 alloy tool steel that is composed of 1.6% carbon(C), 0.4% silicon(Si), 0.6% manganese (Mn), 5% chromium (Cr), 1% molybdenum(Mo) and vanadium(V). The density of it was $7.89g/cm^3$.Using tally card 6, we calculated the shielding efficiency of MLC according to tube voltage. The results was that 98.3% (80 kVp), 95.7 %(100 kVp), 93.6% (120 kVp). We certified efficiency of diagnostic MLC fabricated from SKD11 alloy steel by monte calro simulation. Based on the results, we designed the diagnostic MLC and will develop the diagnostic MLC for reduction of patient dose in diagnostic radiography.

• Journal of the Korean Society of Marine Environment & Safety
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• v.25 no.1
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• pp.18-26
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• 2019

The Maritime Labour Convention, 2006, (MLC) aimed to ensure decent working conditions for seafarers and entered into force on August 20, 2013. It was considered as the fourth pillar in the maritime sector. This paper evaluates how the MLC has been implemented in the field and what issues were addressed in the shipping industry. To achieve this, statistical analysis was conducted using inspection data of Port State Control (PSC) carried out by the Paris MOU and the Tokyo MOU during 2010-2012 and 2014-2016 for deficiencies under the MLC and International Labour Organization (ILO) No. 147 Convention. This study compared pre-2013 and post-2013 deficiency data according to ship's age, size (gross tonnage) and type. The results showed that, although the deficiencies reported by the Tokyo MOU during 2014-2016 were nearly double those from 2010-2012, the deficiency share against total deficiencies for the Tokyo MOU remained two thirds of those for the Paris MOU. This study suggests that the Tokyo MOU should strengthen its inspection efforts on MLC and ILO should provide clear references, such as guidelines and a unified interpretation for national discretions under the MLC for the purpose of harmonized PSC inspections. Additionally, it would be desirable to consolidate the deficiency coding system for the MLC by deleting the codes for the ILO No. 147 Convention, which was incorporated into the MLC. It would also be beneficial to add new deficiency codes for social security, including seafarers' leave and repatriation.

• Journal of the Korean Society of Radiology
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• v.16 no.7
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• pp.863-870
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• 2022

DLG (Dosimetric Leaf Gap) and transmission factor are important parameters of MLC modeling in treatment planning system. In this study, DLG and transmission factor of HD-MLC were measured using detector with different measuring volumes, and the accuracy of the treatment plans was evaluated according to the DLG values. DLG was measured using the dynamic sweeping gap method with Semiflux3D and MicroDiamond detectors. Then, 10 radiation treatment plans were generated to optimize the DLG value and compared with the measurement results. Photon energies 6, 8, 10 MV, the DLG measured by Semiflux3D were 0.76, 0.83, and 0.85 mm, and DLG measured by MicroDiamond were 0.78, 0.86, and 0.9 mm. All plans were measured by portal dosimetry and analyzed using Gamma Evaluation. In the 6 MV photon beams, the average gamma passing rate were 94.3% and 98.4% for DLG 0.78 mm and 1.15 mm. In the 10 MV photon beam, the average gamma passing rate were 91.2% and 97.6% for DLG 0.9 mm and 1.25 mm. HD-MLC needs accurate modeling in the treatment planning system. DLG could be used measured data using small volume detector. However, for better radiation therapy, DLG should be optimized at the commissioning stage of LINAC.

• The Korean Journal of Physiology and Pharmacology
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• v.21 no.1
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• pp.99-106
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• 2017

Obesity is a critical risk factor for the hypertension. Although angiotensin II (Ang II) in obese individuals is known to be upregulated in obesity-induced hypertension, direct evidence that explains the underlying mechanism for increased vascular tone and consequent increase in blood pressure (BP) is largely unknown. The purpose of this study is to investigate the novel mechanism underlying Ang II-induced hyper-contractility and hypertension in obese rats. Eight-week old male Sprague-Dawley rats were fed with 60% fat diet or normal diet for 4 months. Body weight, plasma lipid profile, plasma Ang II level, BP, Ang II-induced vascular contraction, and expression of regulatory proteins modulating vascular contraction with/without Ang II stimulation were measured. As a result, high fat diet (HFD) accelerated age-dependent body weight gaining along with increased plasma Ang II concentration. It also increased BP and Ang II-induced aortic contraction. Basal expression of p-CPI-17 and myosin light chain (MLC) kinase was increased by HFD along with increased phosphorylation of MLC. Ang II-induced phosphorylation of CPI-17 and MLC were also higher in HFD group than control group. In conclusion HFD-induced hypertension is through at least in part by increased vascular contractility via increased expression and activation of contractile proteins and subsequent MLC phosphorylation induced by increased Ang II.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.48 no.10
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• pp.25-32
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• 2011

We have analyzed adjacent cell dependency of threshold voltage shift caused by the cell to cell interference, and we proposed a 3-adjacent-cell model to model the pattern dependency of the threshold voltage shift. The proposed algorithm is verified by using MATLAB simulation and measurement results. In the experimental results, we found that accuracy of the proposed simple 3-adjacient-cell model is comparable to the widely used conventional 8-adjacient-cell model. The Bit Error Rate (BER) of LSB and of MSB is improved by 28.9% and 19.8%, respectively, by applying the proposed algorithm based on 3-adjacent-cell model to 20nm-class 2-bit MLC NAND flash memories.

• The Journal of the Korea Contents Association
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• v.16 no.3
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• pp.91-101
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• 2016

This paper presents the design of new parallel BCH decoder for MLC NAND flash memory. The proposed decoder supports the multi-byte parallel operations to enhance its throughput. In addition, it employs a LFSR-based parallel syndrome generator for compact hardware design. The proposed BCH decoder is synthesized with hardware description language, VHDL and it is verified using Xilinx FPGA board. From the simulation results, the proposed BCH decoder enhances the throughput by 2.4 times than its predecessor employing byte-wise parallel operation. Compared to the other counterpart employing a GFM-based parallel syndrome generator, the proposed BCH decoder requires the same number of cycles to complete the given works but the circuit size is reduced to less than one-third.

• Korean Journal of Veterinary Research
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• v.20 no.2
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• pp.79-84
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• 1980

One hundred and eighteen cultures of Gram-negative rods isolated from cases of clinical bovine mastitis during lactation were examined for distribution of specific types, and activity of several antimicrobial agents to the isolates was determined by two-fold tube dilution method employing sterile whole milk as fluid medium. Of the isolates, 59.2% were Escherichia coli. Most of the remaining isolates were Klebsiella pneumoniae and Enterobacter aerogenes. Most Gram-negative rods(89.8%) were isolated from acute local and chronic mastitis. The cases of peracute systemic form with a marked symptoms of toxemia were associated with Escherichia coli and Klebsiella pneumoniae. The minimal lethal concentrations (MLC) of gentamicin and oxolinic acid in sterile whole milk were 16-128 times higher than the MLC obtained in trypticase soy broth (TSB), while the MLC of ampicillin and tetracycline in milk increased 2-4 times compared with TSB. Of the drugs tested, gentamicin was the most active antibiotics with MLC of $100{\mu}g/ml$ in sterile whole milk against all of Gram-negative rods isolated from bovine udder infections.

• Journal of radiological science and technology
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• v.42 no.5
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• pp.365-371
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• 2019

We have developed and applied a diagnostic Multi-Leaf Collimator (MLC) to optimized the X-ray field in medical imaging and the usefulness evaluated through the fusion of infrared image and X-ray image acquired by infrared camera. The hand and skull radiography with multi-leaf collimator(MLC) showed significant area dose reductions of 22.9% and 31.3% compared to ARC and leakage dose was compliant with KS A 4732. Also scattering doses of 50 cm and 100 cm showed a significant decrease to confirm the usefulness of MLC. It was confirmed that the fusion of infrared images with an adjustable degree of transparency was possible in the X-ray images. Therefore, fusion of anatomical information with physiological convergence is expected to contribute and improvement of diagnostic ability. In addition, the feasibility of convergence X-ray imaging and DITI devices and the possibility of driving MLC with infrared images were confirmed.

• 한국공간정보시스템학회:학술대회논문집
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• 2005.11a
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• pp.17-22
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• 2005

Generally, pixel-based classification, utilize the similarity of distances between the pixel values in feature space, is applied to land use mapping using satellite remote sensing data. But this method is Improper to be applied to the very high resolution satellite data (VHRS) due to complexity of the spatial structure and the variety of pixel values. In this paper, we performed the hierarchical classification of VHRS imagery by data fusion, which integrated LiDAR height and intensity information. MLC and ISODATA methods were applied to IKONOS-2 imagery with and without LiDAR data prior to the hierarchical classification, and then results was evaluated. In conclusion, the hierarchical method with LiDAR data was the superior than others in VHRS imagery and both MLC and ISODATA classification with LiDAR data were better than without.

• Molecules and Cells
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• v.25 no.1
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• pp.78-85
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• 2008

In a search for new molecular pathways associated with asthma, we performed an mRNA differential display analysis using total RNA extracted from the tracheal tissues of ovalbumin (OVA)-challenged mice and sham controls. cDNAs corresponding to mRNAs for which expression levels were altered by OVA-challenge were isolate and sequenced. Twenty-eight genes differentially expressed in sham and OVA challenged mice were identified. A GenBank BLAST homology search revealed that they were related to cytoskeleton remodeling, transcription, protein synthesis and modification, energy production, and cell growth and differentiation. Two were selected for further characterization. Up-regulation of both the perinatal skeletal myosin heavy chain (skMHC) and fast skeletal muscle myosin light chain (skMLC) genes was confirmed by RT-PCR of trachea tissue from OVA challenged mice. Overexpression of skMLC protein was observed in the smooth muscle layers of OVA-challenged mice by immunohistochemistry, and the surface areas stained with skMLC antibody increased in the OVA-challenged mice. The overexpression of skMLC in murine asthma may be associated with the changes of bronchial smooth muscle.