• Title/Summary/Keyword: MIS 7

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Minimally Invasive Surgery without Decompression for Hepatocellular Carcinoma Spinal Metastasis with Epidural Spinal Cord Compression Grade 2

  • Jung, Jong-myung;Chung, Chun Kee;Kim, Chi Heon;Yang, Seung Heon
    • Journal of Korean Neurosurgical Society
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    • v.62 no.4
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    • pp.467-475
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    • 2019
  • Objective : There is a lack of knowledge regarding whether decompression is necessary in treating patients with epidural spinal cord compression (ESCC) grade 2. The purpose of this study was to compare the outcomes of minimally invasive surgery (MIS) without decompression and conventional open surgery (palliative laminectomy) for patients with hepatocellular carcinoma (HCC) spinal metastasis of ESCC grade 2. Methods : Patients with HCC spinal metastasis requiring surgery were retrospectively reviewed. Patients with ESCC grade 2, medically intractable mechanical back pain, a Nurick grade better than 3, 3-6 months of life expectancy, Tomita score ${\geq}5$, and Spinal Instability Neoplastic Score ${\geq}7$ were included. Patients with neurological deficits, other systemic illnesses and less than 1 month of life expectancy were excluded. Thirty patients were included in the study, including 17 in the open surgery group (until 2008) and 13 in the MIS group (since 2009). Results : The MIS group had a significantly shorter operative time ($94.2{\pm}48.2minutes$ vs. $162.9{\pm}52.3minutes$, p=0.001), less blood loss ($140.0{\pm}182.9mL$ vs. $1534.4{\pm}1484.2mL$, p=0.002), and less post-operative intensive care unit transfer (one patient vs. eight patients, p=0.042) than the open surgery group. The visual analogue scale for back pain at 3 months post-operation was significantly improved in the MIS group than in the open surgery group ($3.0{\pm}1.2$ vs. $4.3{\pm}1.2$, p=0.042). The MIS group had longer ambulation time ($183{\pm}33days$ vs. $166{\pm}36days$) and survival time ($216{\pm}38days$ vs. $204{\pm}43days$) than the open surgery group without significant difference (p=0.814 and 0.959, respectively). Conclusion : MIS without decompression would be a good choice for patients with HCC spinal metastasis of ESCC grade 2, especially those with limited prognosis, mechanical instability and no neurologic deficit.

Plasma Polymerized Styrene for Gate Insulator Application to Pentacene-capacitor (유기박막트랜지스터 응용을 위해 플라즈마 중합된 Styrene 게이트 절연박막)

  • Hwang, M.H.;Son, Y.D.;Woo, I.S.;Basana, B.;Lim, J.S.;Shin, P.K.
    • Journal of the Korean Vacuum Society
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    • v.20 no.5
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    • pp.327-332
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    • 2011
  • Plasma polymerized styrene (ppS) thin films were prepared on ITO coated glass substrates for a MIM (metal-insulator-metal) structure with thermally evaporated Au thin film as metal contact. Also the ppS thin films were applied as organic insulator to a MIS (metal-insulatorsemiconductor) device with thermally evaporated pentacene thin film as organic semiconductor layer. After the I-V and C-V measurements with MIM and MIS structures, the ppS revealed relatively higher dielectric constant of k=3.7 than those of the conventional poly styrene and very low leakage current density of $1{\times}10^{-8}Acm^{-2}$ at electric field strength of $1MVcm^{-1}$. The MIS structure with the ppS dielectric layer showed negligible hysteresis in C-V characteristics. It would be therefore expected that the proposed ppS could be applied as a promising dielectric/insulator to organic thin film transistors, organic memory devices, and flexible organic electronic devices.

Marine Terrace of Daebo-Guryongpo-Gampo, SE Korea(II) (대보-구룡포-감포 지역의 해안단구(II))

  • 최성자
    • Economic and Environmental Geology
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    • v.37 no.2
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    • pp.245-253
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    • 2004
  • The 36km-long Daebo-Campo coast has a well-developed marine terraces divided to six steps by elevation of paleoshoreline : 0.5 m(T1), 10 m(T2), 30 m(T3), 40 m(T4), 60 m(T5) and 75 m(T6). The 2$^{nd}$ and 3$^{nd}$ platforms in Daebo to Guryongpo are wider and more distinctive than those of Guryongpo to Gampo. The 3$^{nd}$ terrace of 30 m high is subdivided to two flights as lower(T3b) and upper(T3a) by old sea cliff. Platform age is unclear because of coral fossil free. However, the terrace age could be determined with convergent OSL ages from beach sediments on 2$^{nd}$ step(T2). OSL ages of the terrace of 10 m high range in 60-70 ka. It reveals that the 2$^{nd}$ -step platform correlates to Oxygen Isotope Time scale, substage 5a(ca. 80 ka), and that uplift rate is ca. 0.19 m/ka for 2$^{nd}$ terrace at Daebo-Campo coast. If considering equivalent uplift rate for all terraces since the Late Pleistocene, the 3$^{rd}$ and 4$^{th}$ terraces would be 5e substage and 7 stage. The 30 m-high terrace provides a good indicator for uplift at Daebo-Gampo coast since 125,000 yrs(MIS 5e). It suggests that the local neotectonic deformation might cause an optional uplift rate of ca. 0.19 m/ka along the SE coast of Korea.

Multisystem Inflammatory Syndrome in Children (MIS-C) (소아 다기관 염증 증후군)

  • Lee, Joon Kee;Cho, Eun Young;Lee, Hyunju
    • Pediatric Infection and Vaccine
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    • v.28 no.2
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    • pp.66-81
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    • 2021
  • The coronavirus disease 2019 pandemic has been continuously spreading throughout the world. As of July 15, 2021, there have been more than 188 million confirmed cases and more than 4.06 million deaths. Although the incidence of severe infections is relatively low in children and adolescents compared to adults, a complication called multisystem inflammatory syndrome in children (MIS-C) may occur in some cases at approximately 2-6 weeks after severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. MIS-C can be seen in patients of various ages, from young infants to adolescents, and may present with diverse clinical manifestations. While fever present in a great majority of patients, symptoms suggesting the involvement of the digestive or nervous system and the skin and mucous membranes (Kawasaki disease-like symptoms) also appear in many cases. Cardiac involvement may also be observed, including left ventricular dysfunction, myocarditis, coronary artery dilatation, and coronary aneurysm. In some cases, hypotension or shock can occur, and mechanical ventilation or treatment in the intensive care unit may be necessary. Fortunately, recovery is generally reported after appropriate treatment. MIS-C is a rare but important complication of SARS-CoV-2 infection in children and adolescents. As such, it is important to recognize the clinical symptoms and provide appropriate treatment at an early stage. In this review, the epidemiology, clinical symptoms, suggested pathophysiology, diagnostic approach, and treatment of MIS-C will be discussed.

A Method of Preventing Blackout Caused by Relay (계전기 동작에 의한 광역정전 방지방안)

  • Jin, B.G.;Lee, S.J.;Kim, S.T.
    • Proceedings of the KIEE Conference
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    • 2007.07a
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    • pp.7-8
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    • 2007
  • This paper presents an vulnerability index for hidden failure of protective relays in transmission system. The bad influence can be quantized by an vulnerability index. When there is mis-operation, no-operation or mis-setting, power flow can be quantized by an index. According to the index, relays can be resetting. So the wide area blackout can be prevented.

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CFD Explanation and Verification of Multi Inner Stage Cyclone for The Particle Removal (미세입자 제거를 위한 Multi Inner Stage Cyclone의 CFD 해석 및 검증)

  • Lee, Sang Jun;Kim, Chun-Lee;Lee, Won Joo
    • Journal of the Korea Society of Computer and Information
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    • v.18 no.1
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    • pp.149-156
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    • 2013
  • In this paper, Commercial program, STAR-CCM+, was used for computer simulation. And also Multi Inner Stage(MIS) cyclone which especially designed for the real experiments of particle removal efficiency. Under negative pressure condition of outlet, computer simulation was performed to predict the removal efficiency for $5{\mu}m$ and $10{\mu}m$ particles by using a turbulence model and lagrangian method. The simulation results are 55.7% and 64.1% for $5{\mu}m$ and $10{\mu}m$ particles, respectively. To compare the simulation results with the actual test of MIS cyclone, we generated the $SiO_2$ particles by heat reactor. Although removal efficiency of actual tests is 63~76% at different flow rate, the size of $SiO_2$ particles which confirmed by SEM(scanning electron microscope) and WAPS(wide range aerosol particle spectrometer) is too small(15~30nm) to compare each results. And so the alternative experiments were performed by using commercial alumina particles ($5{\mu}m$, $10{\mu}m$ and $20{\mu}m$). It was shown that the actual removal efficiency, 76~95%, from MIS cyclone is higher than simulated one.

Properties of Deposits and Geomorphic Formative Ages on Marine Terraces in Gwangyang Bay, South Sea of Korea (광양만 일대 해안단구의 퇴적물 특성과 지형 형성시기)

  • Lee Gwang-Ryul;Park Chung-Sun
    • Journal of the Korean Geographical Society
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    • v.41 no.3 s.114
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    • pp.346-360
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    • 2006
  • In order to analyze synthetically geomorphological processes of marine terrace in Korea, this study deals with the distribution of marine terraces, stratification of sedimentary layers, physicochemical properties of deposits, and formative ages of marine terraces based on OSL(Optically Stimulated Luminescence) absolute age at coastal area of Gwangyang Bay in central part of the South Coast. As a result of comparison with physicochemical properties on diverse geomorphic materials, there is not enough distinction in them, because of recycling and mixing of materials at Gwangyang Bay having a geomorphic closure. In Gwangyang bay coast, marine terraces are discovered at least 3 levels and have a small area. Formative age of 1st Terrace, as the lowest level ranging in $10{\sim}13m$ above the sea level, is estimated at MIS(Marine Isotope Oxygen Stage) 5a, based on OSL age dating and properties of deposits. Uplifting rate is calculated at 0.141m/ka in Gwangyang bay coast. For application to this rate, 2nd terrace($18{\sim}22m$) is estimated at MIS 5e, 3rd terrace($27{\sim}32m$) is latter part of MIS 7. Consequently, we might conclude that uplifting and geomorphic process of marine terrace in South Coast is similar to East Coast during the Late Pleistocene in Korea.

Clinical spectrum and short-term outcomes of multisystem inflammatory syndrome in children in a south Indian hospital

  • Balagurunathan, Muruganantham;Natarajan, Thrilok;Karthikeyan, Jothilakshmi;Palanisamy, Venkateshwaran
    • Clinical and Experimental Pediatrics
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    • v.64 no.10
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    • pp.531-537
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    • 2021
  • Background: Multisystem inflammatory syndrome in children (MIS-C) is a new hyperinflammatory variant that evolved during the coronavirus disease 2019 pandemic. Although the precise pathophysiology of MIS-C is uncertain, it is thought to be due to immune dysregulation occurring after recovery from acute infection. Purpose: Our study aimed to analyze the clinical spectrum, laboratory parameters, imaging characteristics, treatment strategies, and short-term outcomes of children with a diagnosis of MIS-C. Methods: This retrospective and prospective observational study included children less than 16 years of age who were admitted to the pediatric unit of a tertiary care teaching hospital in south India between August 2020 to January 2021 with a diagnosis of MIS-C according to World Health Organization criteria. Results: Twenty-one children were included in the analysis; all had fever with variable combinations of other symptoms. The mean age was 6.9 years; 71.4% were male. Gastrointestinal (80.9%) and cardiovascular (80.9%) systems were the most commonly affected. The majority of children had elevated inflammatory markers, and 16 (76.2%) had echocardiographic abnormalities mimicking Kawasaki disease. Eleven children (52.4%) required intensive care admission, 3 (14.3%) required supplemental oxygen, and 4 (19%) required inotropes. Nine (42.9%) were treated with intravenous immunoglobulin alone, 6 (28.6%) with steroids alone, and 3 (14.3%) with steroids and immunoglobulin. The median hospital stay was 6 days; there were no fatalities. Overweight/obesity, elevated ferritin, and mucocutaneous involvement were significantly associated with a prolonged hospital stay (≥7 days). Sixteen children (76.2%) were followed up till now and all of them had no clinical concerns. Conclusion: MIS-C is an emerging disease with variable presentation. A high index of suspicion is necessary for its early identification and appropriate management. Further research is essential for developing optimal treatment strategies.

A Study on the Indicators of Informatization Maturity Level and Critical Success Factors in Small and Medium Manufacturers: A Case of Automotive Parts Industry (중소제조업체의 정보화 성숙도 지표 개발 및 성공요인 도출: 자동차 부품업체 사례)

  • Joo, Suk-Jung;Yoo, San-Gin;Kim, Na-Rang;Hong, Soon-Goo
    • Information Systems Review
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    • v.7 no.2
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    • pp.195-211
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    • 2005
  • The purpose of this case study is to suggest the indicators of an informatization maturity level and critical success factors in small and medium automotive parts manufacturers. To achieve this goal, literature reviews and case studies on 7 automotive parts manufacturers that confirmed to implement information systems successfully, were conducted. Based on literature review, the six functional processes including development, production scheduling, purchase, production, order, and support process, were defined. Each process has 5 levels from 1(low level) to 5(high level) depending on the degree of informatization maturity. In addition, critical success factors were discovered with interviews of CEO or CIO. The results of this study can be applied to any companies which are implementing or intended to the information systems near future.