• Korean Management Science Review
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• v.20 no.1
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• pp.65-76
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• 2003

The increased environmental concerns and the emphasis on recycling are gradually shifting the orientation of municipal solid waste (MSW) management. This paper is designed to evaluate regionalization programs for MSW management system. We developed a mixed intiger network programming (MIP) model to identify environment-friendly, cost-effective expansion plans for regionalization scenarios considered. The MIP model is a dynamic capacity expansion model based on the network flow model that depicts the MSW management cycle. In particular, our model is designed to determine the optimal form of regionalization using binary variables. We apply this model to assess the regionalization program of Seoul Metropolitan City, which includes three scenarios such as 1) districting, 2) regionalization with neighboring self-governing districts, and 3) g1obalization with all districts. We demonstrate how our model can be used to plan the MSW system. The results indicate that optimal regionalization with nearby self-governing districts can eliminate unnecessary landfills and expansions if jurisdictional obstacles are removed.

• Journal of Life Science
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• v.13 no.4
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• pp.383-389
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• 2003

A cDNA (SeMIPS) encoding myo-inositol 1-phosphate synthase has been isolated from developing sesame (Sesamum indicum L. cv. Dan-Baek) seeds and its structure and function analyzed. The SeMIPS protein was highly homologous with those from plant species (88-94%), while a much lower degree of sequence homology (60%) was found with that of human. The functional domains commonly found in MIPS protein were identified and their amino acid residues were compared with each other. Northern blot indicated that the expression of the SeMIPS gene might be organ-specifically regulated. A complementation assay based on a yeast mutant system confirmed that the SeMIPS gene encodes a myo-inositol 1-phosphate synthase (MIPS) of sesame by showing functional expression of the SeMIPS cDNA in the yeast mutants containing the disrupted INO1 gene.

• Journal of Periodontal and Implant Science
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• v.27 no.2
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• pp.425-441
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• 1997

The neuropeptide substance P(SP) has been implicated in the mediation of inflammation and immune-mediated disease such as arthritis. Recently, it was reported that SP was markedly increased around the blood vessels in inflamed gingiva as well as in close association with the inflammatory cell infiltrate. These results support that SP may contribute to the pathophysiology of neuronal inflammation in human periodontal tissues. SP may regulate inflammatory/immune responses by stimulating the proliferation of human T cells, differentiation and antibody-secreting potential of B cells, macrophage respiratory burst, connective tissue proliferation, and the secretion of cytokines from monocytes and T cells. Here, I studied potential role of SP as a costimulatory chemical signal in inflammatory/immune responses, by determining the released proinflammatory cytokines such as $MIP-1{\alpha}$, $IL-1{\beta}$, and IL-6 from culture supernatants of homogeneous immune cell lines. Serum free cell supernatants were concentrated with TCA precipitation, fractionated with SDS-PAGE, and subjected into western blot analysis. Among 15 cell lines tested, macrophage/monocyte cell line RAW264.7 and WRl9m.1 showed the highest level of induction of $MIP-1{\alpha}$ when stimulated with LPS. Discrete IL-6 bands with multiple forms of molecular mass were detected from supernatants of B cell lines A20(32kDa), Daudi(32, 35kDa), and SKW6.4(29kDa), which were expressed constitutively. $IL-1{\beta}$ could not be detected by the method of western blot analysis from supernatants of all cell lines tested except RAW264.7, WRl9m.1, and erythroid cell line K562 which showed the least amount of $IL-{\beta}$ secretion. SP $10^{-9}M$ with suboptimal dose of LPS treatment showed synergistic induction of $MIP-1{\alpha}$ release from RAW264.7 or WR19m.1, and also IL-6 release from A20, but this synergism is not the case in costimulation of RAW264.7 or WRl9m.1 with SP $10^{-9}M$ and TPA. Although treatment of T cell line CTLL-R8 with SP $10^{-7}M$ or PHA+TPA induced modest level of $MIP-1{\alpha}$ secretion, synergism was not observed when they are applied together. These findings all together suggest the possibility of a regulatory role of SP in inflammatory/immune reaction through differential modulation of bioactivities of other chemical cosignals.

• The Journal of Korean Society for Radiation Therapy
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• v.28 no.2
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• pp.123-130
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• 2016

Purpose : The aim of this study was to compare the differences between the volumes acquired with four-dimensional computed tomography (4DCT)images with a reconstruction image-filtering algorithm and cone-beam computed tomography (CBCT) images with dynamic phantom. Materials and Methods : The 4DCT images were obtained from the computerized imaging reference systems (CIRS) phantom using a computed tomography (CT) simulator. We analyzed the volumes for maximum intensity projection (MIP), minimum intensity projection (MinIP) and average intensity projection (AVG) of the images obtained with the 4DCT scanner against those acquired from CBCT images with CT ranger tools. Results : Difference in volume for node of 1, 2 and 3 cm between CBCT and 4DCT was 0.54~2.33, 5.16~8.06, 9.03~20.11 ml in MIP, respectively, 0.00~1.48, 0.00~8.47, 1.42~24.85 ml in MinIP, respectively and 0.00~1.17, 0.00~2.19, 0.04~3.35 ml in AVG, respectively. Conclusion : After a comparative analysis of the volumes for each nodal size, it was apparent that the CBCT images were similar to the AVG images acquired using 4DCT.

• Physical Therapy Korea
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• v.25 no.1
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• pp.12-21
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• 2018

Background: Research efforts to improve the pulmonary function of children with cerebral palsy (CP) need to focus on their decreased diaphragmatic ability compared to normal children. Real-time ultrasonography is appropriate for demonstrating diaphragmatic mechanisms. Objects: This study aimed to compare diaphragm movement, pulmonary function, and pulmonary strength between normal children and children with CP by using ultrasonography M-mode. The correlation between general characteristics, diaphragm movement, pulmonary function, and pulmonary strength was also studied. Methods: The subjects of this study were 25 normal and 25 CP children between five and 14 years of age. Diaphragm movement was measured using real-time ultrasonography during quiet and deep breathing. Pulmonary function (such as forced expiratory volume in one second; FEV1 and peak expiratory flow; PEF) and pulmonary strength (such as maximum inspiratory pressure; MIP and maximum expiratory pressure; MEP) were measured. A paired t-test and Spearman's Rho test, with a significance level of .05, were used for statistical analysis. Results: The between-group comparison revealed that normal children had significantly greater diaphragm movement, FEV1, PEF, MIP, and MEP (p<.05) than CP children. The results showed that general characteristics were significantly related to FEV1, PEF, MIP, and MEP (p<.05). Conclusion: In clinical settings, clinicians need to concern decreased diaphragm movement, pulmonary function, and pulmonary strength in CP group compared to normal children.

• Proceedings of the Acoustical Society of Korea Conference
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• autumn
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• pp.151-156
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• 1999

본 논문에서는 국제 표준화기구(ISO) 산하의 동영상 전문가 그룹(MPEG)의 오디오 압축방법들중 하나인 MPEG-I layer 3 의 복호화기를 고정 소수점으로 변환한 후, $OakDSPCore^{\circledR}$를 기반으로 전 과정을 어셈블리어로 실시간 구현하였다. 실시간 구현에 사용된 $OakDSPCore^{\circledR}$는 DSP Group사에서 개발된 저전력 소비형 16-비트 고정 소수점 DSPCore로서 40MIPS의 성능을 가지고 있으며, 음성/오디오, 통신, 디지털 셀룰라폰 같은 소비자의 맞게 ASIC화할 수 있는 장점을 가지고 있다. 구현된 MP3 복호화기는 약33 MIPS의 복잡도를 나타내며, 사용된 메모리양은 프로그램 ROM 3.1K words, 데이터 ROM(table) 10.82K words 및 ROM 6.1K words이다. 구현된 MP3 복호화기는 OMNI-MEDIASOUND에서 제공하는 4개의 test 벡터들을 bit-exact하게 통과하였다.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 1999.11b
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• pp.59-63
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• 1999

본 논문에서는 국제 표준화기구(ISO) 산하의 동영상 전문가 그룹(MPEG)의 오디오 압축방법들중 하나인 MPEG-I layer 3의 복호화기를 고정 소수점으로 변환한 후, OalkDSPCore$\circledR$를 기반으로 전 과정을 어셈블리어로 실시간 구현하였다. 실시간 구현에 사용된 OakDSPCor$\circledR$는 DSPGroup사에서 개발된 저전력 소비형 16-비트 고정소수점 DSPCore로서 40MIPS의 성능을 가지고 있으며, 음성/오디오, 통신, 디지털 셀룰라폰 같은 소비자의 맞게 ASIC화할 수 있는 장점을 가지고 있다. 구현된 MP3 복호화기는 약33 MIPS의 복잡도를 나타내며, 사용된 메모리양은 프로그램 ROM 3.1Kwords, 데이터 ROM(table)10.82Kwords 및 RAM6.1Kwords이다. 구현된 MP3 복호화기는 OMNI-MEDIASOUND에서 제공하는 4개의 test 벡터들을bit-exact하게 통과하였다.

• Industrial Engineering and Management Systems
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• v.10 no.1
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• pp.74-83
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• 2011

In this paper, we consider a new lot-sizing and scheduling problem (LSSP) that minimizes the sum of production cost, setup cost and inventory cost. Setup carry-over, setup overlapping, state dependent setup time as well as demand splitting are considered. For this LSSP, we develop a mixed integer programming (MIP) model, of which the size does not increase even if we divide a time period into a number of micro time periods. Also, we develop an efficient heuristic algorithm by combining a decomposition scheme with a local search procedure. Test results show that the developed heuristic algorithm finds a good quality (in practice, even better) feasible solution using far less computation time compared with the CPLEX, a competitive MIP solver.

• Proceedings of the Korea Concrete Institute Conference
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• 2009.05a
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• pp.345-346
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• 2009

This research focused on large variation of the result of Ca(OH)$_2$ quantity by TG/DTA test or micro-pore size by MIP test. Assume that sample postion has influenced on experimental result, therefore, relationship between sampling position and the experimental result was studied As a result of the research, it is obvious that samples from inside(P-3) shows more Ca(OH)$_2$ and less porosity than samples from outside(P-1).

• Proceedings of the Korean Institute of Building Construction Conference
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• 2016.10a
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• pp.32-33
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• 2016

This purpose of this study is to find the properties of pore structure and length change of blast furnace slag cement added alkali powder stimulant on shrinkage reducing agent presence. In length change, the specimen added alkaline stimulant was smaller than normal blast furnace slag concrete. And the specimen added shrinkage reduction agent was confirmed to show smaller rate of length change than the length. In MIP analysis of 1day-age, 0.1㎛ subsequent pore amount of the specimen added alkaline stimulant was significantly smaller value the normal blast furnace slag concrete specimen.