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Thixoforming을 위한 Al-7%Si-0.3%Mg 합금의 유도 가열 조건이 구상화 조직에 미치는 영향 (Effect of Induction Heating Conditions on Globular Microstructure of Al-7%Si-0.3%Mg Alloy for Thixoforming)

  • 정홍규;강충길
    • 한국주조공학회지
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    • 제18권5호
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    • pp.450-461
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    • 1998
  • The optimal reheating conditions to apply the thixoforging and semi-solid die casting process were investigated by changing the reheating time, the holding time, the reheating temperatures, the capacity of the induction heating system, and the adiabatic material size. In the case of solid fraction fs=50% (for semi-solid die casting), the microstructure of SSM (specimen size:$d76{\times}l90$) at the condition of the first elevating time of 4 min, holding time of 1 min and holding temperature of $350^{\circ}C$, the second elevating time of 3 min, holding time of 3 min and holding temperature of $575^{\circ}C$, the third elevating time of 1 min, holding time of 2 min and holding temperature of $584^{\circ}C$, capacity of Q=8.398KW is obtained with globular microstructure and finest. In addition, in the case of solid fraction fs=55% (for thixoforging), the SSM (specimen size:$d76{\times}l90$) at the condition of the first elevating time of 4 min, holding time of 1 min and holding temperature of $350^{\circ}C$, the second elevating time of 3 min, holding time of 3 min and holding temperature of $570^{\circ}C$, the third elevating time of 1 min, holding time of 2 min and holding temperature of $576^{\circ}C$, capacity of Q=12.04KW is obtained with the finest globular microstructure. We saw that the most important factor in a three-step reheating process is the final holding time.

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혈액투석 시 투석액 속도가 투석적절도와 피로에 미치는 효과 (The Effect of Dialysate Flow Rate on Dialysis Adequacy and Fatigue in Hemodialysis Patients)

  • 차선미;민혜숙
    • 대한간호학회지
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    • 제46권5호
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    • pp.642-652
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    • 2016
  • Purpose: In this single repeated measures study, an examination was done on the effects of dialysate flow rate on dialysis adequacy and fatigue in patients receiving hemodialysis. Methods: This study was a prospective single center study in which repeated measures analysis of variance were used to compare Kt/V urea (Kt/V) and urea reduction ratio (URR) as dialysis adequacy measures and level of fatigue at different dialysate flow rates: twice as fast as the participant's own blood flow, 500 mL/min, and 700 mL/min. Thirty-seven hemodialysis patients received all three dialysate flow rates using counterbalancing. Results: The Kt/V ($M{\pm}SD$) was $1.40{\pm}0.25$ at twice the blood flow rate, $1.41{\pm}0.23$ at 500 mL/min, and $1.46{\pm}0.24$ at 700 mL/min. The URR ($M{\pm}SD$) was $68.20{\pm}5.90$ at twice the blood flow rate, $68.67{\pm}5.22$ at 500 mL/min, and $70.11{\pm}5.13$ at 700 mL/min. When dialysate flow rate was increased from twice the blood flow rate to 700 mL/min and from 500 mL/min to 700 mL/ min, Kt/V and URR showed relative gains. There was no difference in fatigue according to dialysate flow rate. Conclusion: Increasing the dialy-sate flow rate to 700 mL/min is associated with a significant increase in dialysis adequacy. Hemodialysis with a dialysate flow rate of 700 mL/min should be considered in selected patients not achieving adequacy despite extended treatment times and optimized blood flow rate.

외판원 문제의 확장된 k-opt 알고리즘 (The Extended k-opt Algorithm for Traveling Salesman Problem)

  • 이상운
    • 한국컴퓨터정보학회논문지
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    • 제17권10호
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    • pp.155-165
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    • 2012
  • 본 논문은 지금까지 해결하지 못한 NP-Hard 문제들 중의 하나인 외판원 문제를 해결할 수 있는 알고리즘을 제안한다. 제안된 알고리즘은 간선교환 방법을 적용한 발견적 알고리즘이다. 초기해를 구하는 전형적인 방법은 첫 번째 노드부터 가장 인접한 노드를 방문하여 외판원의 경로를 결정하는 방법이다. 본 논문에서는 각 노드의 최소 간선을 선택하여 선택된 간선들 중 최소값을 가진 노드부터 출발하는 Min-Min 방법과 최대값을 가진 노드부터 출발하는 Min-Max 방법을 적용하고 두 방법 중 최소 경로길이를 가진 방법을 초기해로 결정하였다. 초기해로부터 최적해를 구하는 과정은 기존의 2-간선 교환 방법 (2-opt)을 기본적으로 적용하고, 추가로 확장된 3-opt와 4-opt를 제안하였다. 이와 같은 방법을 7개의 실제 데이터들에 적용한 결과 지금까지 알려진 최적해를 빠르고 정확히 구하는데 성공하였다.

자기 지도 학습훈련 기반의 Noise2Void 네트워크를 이용한 PET 영상의 잡음 제거 평가: 팬텀 실험 (The Evaluation of Denoising PET Image Using Self Supervised Noise2Void Learning Training: A Phantom Study)

  • 윤석환;박찬록
    • 대한방사선기술학회지:방사선기술과학
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    • 제44권6호
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    • pp.655-661
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    • 2021
  • Positron emission tomography (PET) images is affected by acquisition time, short acquisition times results in low gamma counts leading to degradation of image quality by statistical noise. Noise2Void(N2V) is self supervised denoising model that is convolutional neural network (CNN) based deep learning. The purpose of this study is to evaluate denoising performance of N2V for PET image with a short acquisition time. The phantom was scanned as a list mode for 10 min using Biograph mCT40 of PET/CT (Siemens Healthcare, Erlangen, Germany). We compared PET images using NEMA image-quality phantom for standard acquisition time (10 min), short acquisition time (2min) and simulated PET image (S2 min). To evaluate performance of N2V, the peak signal to noise ratio (PSNR), normalized root mean square error (NRMSE), structural similarity index (SSIM) and radio-activity recovery coefficient (RC) were used. The PSNR, NRMSE and SSIM for 2 min and S2 min PET images compared to 10min PET image were 30.983, 33.936, 9.954, 7.609 and 0.916, 0.934 respectively. The RC for spheres with S2 min PET image also met European Association of Nuclear Medicine Research Ltd. (EARL) FDG PET accreditation program. We confirmed generated S2 min PET image from N2V deep learning showed improvement results compared to 2 min PET image and The PET images on visual analysis were also comparable between 10 min and S2 min PET images. In conclusion, noisy PET image by means of short acquisition time using N2V denoising network model can be improved image quality without underestimation of radioactivity.

공조풍량별 식생바이오필터의 입자상 오염물질 저감효과 연구 (A Study on Particulate Matter Reduction Effects of Vegetation Bio-Filters by Airflow Volume)

  • 최부헌;김태한
    • 반도체디스플레이기술학회지
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    • 제20권4호
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    • pp.89-95
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    • 2021
  • As the influence of fine dust on society spreads gradually, the public's interest in indoor air is increasingly rising. Air-purifying plants are drawing keen attention due to their natural purifying function enabled by plant physiology. However, as their fine dust reduction mechanism is limited to adsorption only, vegetation bio-filters that optimize purification effects through integration with air-conditioning systems is rising as an alternative. In accordance with the relevant standard test methods, this study looked into the fine dust reduction assessment method by air-conditioning airflow volume that can be used for the industrial spread of vegetation bio-filters. In the case of PM10 at 300 ㎍/m3, it was in the order of EG-B(3,500CMH, 29 min.) < EG-A (2,500CMH, 37 min.) < CG(0CMH, 64 min.) for reaching the maintenance level (100 ㎍/m3) of publicly used facilities. For reaching the WHO Guideline(50 ㎍/m3) requirement, it was in the order of EG-B (51 min.) < EG-A (160 min.) < CG (170 min.). In the case of PM2.5, it was in the order of EG-B (26 min.) < EG-A (33 min.) < CG (57 min.) for reaching the maintenance level (50 ㎍/m3) of publicly used facilities. It was in the order of EG-B (48 min) < EG-A (140 min) < CG (158 min) for reaching the WHO Guideline (25 ㎍/m3) requirement. The findings from the analysis showed that fine dust can be reduced most efficiently when the system is operated at 3,500CMH level. The limitation of this study is that due to the absence of a way of assessing the stress of plants in vegetation bio-filters, generating optimal air-conditioning air flow of the relevant system and economics analysis against the existing facility-type air purification system have been clarified, which should be explored further though follow-up studies.

홉필드 네트워크와 퍼지 Max-Min 신경망을 이용한 손상된 교통 표지판 인식 (Damaged Traffic Sign Recognition using Hopfield Networks and Fuzzy Max-Min Neural Network)

  • 김광백
    • 한국정보통신학회논문지
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    • 제26권11호
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    • pp.1630-1636
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    • 2022
  • 현재 교통 표지판 인식 기법들은 다양한 날씨, 빛의 변화 등과 같은 외부환경 뿐만 아니라 교통 표지판이 일부 훼손된 경우에는 인식 성능이 저하되는 경우가 발생한다. 따라서 본 논문에서는 이러한 문제점을 개선하기 위하여 홉필드 네트워크와 퍼지 Max-Min 신경망을 이용하여 손상된 교통 표지판의 인식 성능을 개선하는 방법을 제안한다. 제안된 방법은 손상된 교통 표지판에서 특징들을 분석한 후, 그 특징들을 학습 패턴으로 구성하여 퍼지 Max-Min 신경망에 적용하여 1차적으로 교통 표지판의 특징을 분류한다. 1차적 분류된 특징이 있는 학습 영상들을 홉필드 네트워크에 적용하여 손상된 특징을 복원한다. 홉필드 네트워크를 적용하여 복원된 교통 표지판의 특징들을 다시 퍼지 Max-Min 신경망에 적용하여 최종적으로 손상된 교통 표지판을 분류하고 인식한다. 제안된 방법의 성능을 평가하기 위하여 손상된 정도가 다른 다양한 교통 표지판 8개를 적용하여 실험한 결과, 제안된 방법이 퍼지 Max-Min 신경망에 비해 평균적으로 38.76%의 분류 성능이 개선되었다.

냉혈K+ 심정지약을 사용한 개심술 예에서 심정지시간에 따른 심근보호효과에 관하여 (Clinical Observations on Myocardial Protection with Cold Blood Potassium Cardioplegia According to the Duration of Ischemic Arrest)

  • 정정기;이동준
    • Journal of Chest Surgery
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    • 제24권7호
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    • pp.647-655
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    • 1991
  • The efficacy of cold blood potassium cardioplegia during periods of ischemic arrest was assessed in 88 patients undergoing open heart surgical procedures at Chonnam National University Medical School from December, 1987 to January, 1989. The purpose of this study was to determine if the aortic cross clamping time[ACCT] over 120 minutes correlated with operative mortality, incidence of postoperative ventricular tachyarrhythmias, needs of postoperative inotropic support and serum enzyme levels. The patients were divided according to aortic cross clamping time[less than 120 minutes and 120 minutes or greater]. The results were as follows: 1. The operative mortality was 3.2% in ACCT<120min group and 7.7% in ACCT>120 min group. 2. The incidence of postoperative ventricular tachyarrhythmia was 1.6% in ACCT <120min group and 11.5% in ACCT>120min group[p<0.05]. 3. The incidence of postoperative inotropic support in congenital heart disease was 13.0Fo in ACCT<120min group and 45.0%o in ACCT>120min group[p<0.05]. The incidence in acquired heart disease was 26.0% in ACCT<120min group and 40.0% in ACCT> 120min group. 4. After cardiopulmonary bypass, serum GOT, LDH, CPK and CPK - MB were elevated prominently. Children showed higher value of the enzymes examined than adults did before and after cardiopulmonary bypass. In congenital heart diseases, postoperative serum GOT, LDH, CPK and CPK - MB levels of ACCT>120min group were significantly higher than those of ACCT<120min group. Postoperative serum GOT, LDH and CPK - MB levels of ACCT>=120min group were significantly higher than those of ACCT<120min group also in acquired heart diseases. The results suggest that the myocardial protective effect with cold blood potassium cardioplegic solutions was not sufficient when the aortic cross clamping time was over 120 minutes.

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감귤 추출물로부터 D-리모넨 분리를 위한 유사 이동층 크로마토그래피(SMB) 전산모사 (Simulation of D-limonene Separation from Mandarine Extract in Simulated Moving Bed (SMB))

  • 김태호;고관영;김인호
    • Korean Chemical Engineering Research
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    • 제54권1호
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    • pp.81-88
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    • 2016
  • 리모넨은 오렌지 향이 있는 천연의 키랄 화합물로 주로 감귤껍질과 레몬껍질에 함유되어 있다. $4^{\circ}C$로 냉장 보관한 감귤 껍질을 에탄올을 용매로 속슬렛 추출기에서 2시간동안 $120^{\circ}C$에서 추출하였다. 역상 HPLC 분석을 통해 d-리모넨과 불순물의 헨리 상수를 계산하여 $H_{Lim}=8.55$, $H_{imp}=0.223$를 얻었다. Aspen chromatography 프로그램을 사용해서 $0.46{\times}25cm$ 칼럼으로 이루어진 4-bed SMB의 리모넨 전산모사를 수행하였고 삼각도내의 $m_2$, $m_3$ 값을 변경하면서 순도가 가장 높은 분리 조건을 찾았다. 그 결과 가장 높은 순도는 98.59%이고, $m_2=2.57$, $m_3=9.55$였다. 이 때의 feed 유량은 1 mL/min, desorbent 유량은 1.19 mL/min, extract 유량은 0.857 mL/min, raffinate 유량은 1.34 mL/min이었다. Scale-up 전산모사를 위해 칼럼의 직경을 1.6 cm로 늘린 4-bed SMB에서 직경이 0.46 cm인 4-bed SMB와 같은 결과를 갖는 조건을 찾기 위해 유량을 칼럼 부피 비에 정비례하여 증가시켰다. 이 때 feed, desorbent, extract, raffinate의 유량은 각각 12 mL/min, 14 mL/min, 10 mL/min, 16 mL/min이었다. 리모넨과 불순물의 등온흡착곡선을 선형으로 가정하였기에 칼럼 부피에 정비례하여 유량을 증가시키는 scale-up이 가능하였다.

동결속도와 침지온도가 Hamster 수정란의 생존성에 미치는 영향 (Effects of Cooling Rates and Plunging Temperatures on Survival of Hamster Embryos)

  • 윤도중;이규승;박창식;서길웅
    • 한국가축번식학회지
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    • 제11권3호
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    • pp.161-169
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    • 1987
  • This experiment was carried out to investigate the optimal cooling rate and the plunging temperature into liquid nitrogen of the 8-cell hamster embryos. The female hamsters were induced to superovulate by intraperitoneal injection of 30 i.u. PMSG. Embryos were flushed from oviduct and uterine horn. Embryos were frozen and incubated with a modified Dulbecco's phosphate buffered saline, and equilibrated with 1.5M-dimethyl sulfoxide by a 3-step procedure. The cooling rate of samples was 1$^{\circ}C$/min from room temperature to -5$^{\circ}C$ and the samples were seeded at -5$^{\circ}C$. The plunging temperatures into liquid nitrogen were -20, -25, -30, -35, -40, -45, -50 and -55$^{\circ}C$ at 0.3$^{\circ}C$/min, 0.5$^{\circ}C$/min and 1$^{\circ}C$/min cooling rates, respectively. This mean numbers of ovulation points and recovered embryos were 59.4 and 48.4 appearing 81.6% recovery rate. The percentage of 8-cell embryos in recovered embryos was 68.2. The survival rates of embryos plunged at -45$^{\circ}C$ were 73.5% at 0.3$^{\circ}C$/min, 44.8% at 0.5$^{\circ}C$/min and 30.3% at 1$^{\circ}C$/min cooling rates, respectively. This mean numbers of ovulation points and recovered embryos were 59.4 and 48.4 appearing 81.6% recovery rate. The percentage of 8-cell embryos in recovered embryos was 68.2. The survival rates of embryos plunged at -45$^{\circ}C$ were 73.5% at 0.3$^{\circ}C$/min, 44.8% at 0.5$^{\circ}C$/min and 30.3% at 1$^{\circ}C$/min cooling rates, respectively. The survival rates at 0.3$^{\circ}C$/min were significantly high. Under the condition of 0.3$^{\circ}C$/min cooling rate, the survival rates of embryos according to the plunging temperature were 70.0% and 73.5% at -40 and -45$^{\circ}C$, and those were higher than other plunging temperatures. Under the condition of 0.5$^{\circ}C$/min and 1$^{\circ}C$/min cooling rates, the survival rates according to the plunging temperatures were lower than the cooling rate of 0.3$^{\circ}C$/min, showing the similar tendency at all the plunging temperatures. In conclusion, 8-cell hamster embryos showed the best survival rates at 0.3$^{\circ}C$/min cooling rate and -45$^{\circ}C$ plunging temperature.

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생쥐 8세포기 수정란의 동결보존에 관한 연구 (Studies on Cryopreservation of 8-Cell Mouse Embryos)

  • 최미후;이규승;박칭식;서길웅
    • 한국가축번식학회지
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    • 제11권3호
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    • pp.155-160
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    • 1987
  • This study was carried out to determine the effects of cryoprotectants, freezing and thawing rates on the survival of 8-cell mouse embryos. The female ICR mice were induced to superovulated by intraperitoneal injections of 5 i.u. PMSG and 5 i.u. HCG given 48h apart and then were paired with males of the same strain. They were killed and embryos were flushed from the oviducts and uteri on 3 days after injection of HCG. Embryos were flushed with modified Dulbecco's phosphate buffered saline and equilibrated with 1.5M-dimethyl sulfoxide (DMSO) or 1.5M-glycerol by 3-step procedure. The freezing rates of the embryos were 1$^{\circ}C$/min from room temperature to -5$^{\circ}C$ and the embryos were seeded at -5$^{\circ}C$. After being held for 3 min at the seeding temperature, the rates were 0.3$^{\circ}C$/min from -5$^{\circ}C$ to -35$^{\circ}C$. From -35$^{\circ}C$ to -7$0^{\circ}C$, the rates were divided into 0.1$^{\circ}C$/min, 1$^{\circ}C$/min and 1$0^{\circ}C$/min, respectively. After being held for 5 min at -7$0^{\circ}C$, the embryos were plunged directly into liquid nitrogen. The embryos were thawed at 4$^{\circ}C$/min and 12$^{\circ}C$/min from -196$^{\circ}C$ to 37$^{\circ}C$, and for 2 min in 37$^{\circ}C$ water bath, respectively. The average number of ovulation points and embryos recovered were 42.7 and 34 appearing 79.5% recovery rate. Eight cell embryos in the embryos recovered were 26.3. The survival rates of embryos according to the freezing rates in the presence of 1.5M-DMSO were 73.5~80.6% at 0.1$^{\circ}C$/min, 75.0~79.5% at 1$^{\circ}C$/min and 52.8~54.7% at 1$0^{\circ}C$/min, but in the presence of 1.5M-glycerol were 62.9~67.6% at 0.1$^{\circ}C$/min, 61.4~68.3% at 1$^{\circ}C$/min and 25.5~30.2% at 1$0^{\circ}C$/min. The survival rates of embryos were not affected by the thawing rates.

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