• 제목/요약/키워드: MFG

검색결과 131건 처리시간 0.028초

Milk Fat Globule-Epidermal Growth Factor VIII Ameliorates Brain Injury in the Subacute Phase of Cerebral Ischemia in an Animal Model

  • Choi, Jong-Il;Kang, Ho-Young;Han, Choongseong;Woo, Dong-Hun;Kim, Jong-Hoon;Park, Dong-Hyuk
    • Journal of Korean Neurosurgical Society
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    • 제63권2호
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    • pp.163-170
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    • 2020
  • Objective : Milk fat globule-epidermal growth factor VIII (MFG-E8) may play a key role in inflammatory responses and has the potential to function as a neuroprotective agent for ameliorating brain injury in cerebral infarction. This study aimed to determine the role of MFG-E8 in brain injury in the subacute phase of cerebral ischemia in a rat model. Methods : Focal cerebral ischemia was induced in rats by occluding the middle cerebral artery with the modified intraluminal filament technique. Twenty-four hours after ischemia induction, rats were randomly assigned to two groups and treated with either recombinant human MFG-E8 or saline. Functional outcomes were assessed using the modified Neurological Severity Score (mNSS), and infarct volumes were evaluated using histology. Anti-inflammation, angiogenesis, and neurogenesis were assessed using immunohistochemistry with antibodies against ionized calcium-binding adapter molecule 1 (Iba-1), rat endothelial cell antigen-1 (RECA-1), and bromodeoxyuridine (BrdU)/doublecortin (DCX), respectively. Results : Our results showed that intravenous MFG-E8 treatment did not reduce the infarct volume; however, the mNSS test revealed that neurobehavioral deficits were significantly improved in the MFG-E8-treated group than in the vehicle group. Immunofluorescence staining revealed a significantly lower number of Iba-1-positive cells and higher number of RECA-1 in the periinfarcted brain region, and significantly higher numbers of BrdU- and DCX-positive cells in the subventricular zone in the MFG-E8-treated group than in the vehicle group. Conclusion : Our findings suggest that MFG-E8 improves neurological function by suppressing inflammation and enhancing angiogenesis and neuronal proliferation in the subacute phase of cerebral infarction.

이온 교환 크로마토그래피에서 온도가 당의 체류 특성에 미치는 영향 (Temperature Effect on the Retention Behavior of Sugars in Ion Exchange Chromatography)

  • 김진일;이종호;구윤모
    • Korean Chemical Engineering Research
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    • 제43권6호
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    • pp.722-727
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    • 2005
  • Dow99Ca350, MFG-220, Finex CS-10GC는 이온 교환 수지로써, 당 분리에 주로 사용되며, 모두 poly styrene DVB를 기본 골격으로 술폰산염, 혹은 술폰산을 작용기로 하고 있다. 이 분리 수지들은 이미 제당 산업의 연속 분리 공정에서 사용되고 있으며, 이에 대해 본 실험은 온도의 영향으로 인한 Dow99Ca350, MFG-220과 Finex CS-10GC의 분리수지에서 당의 체류 혹은 흡착 특성 변화를 알아보기 위하여 수행되었다. 당 분리의 시료로써 사용된 물질은 과당과 포도당으로써 위의 분리 수지와 함께 제당 산업에서 널리 사용된다. Dow99Ca350의 팽윤 시험, 공극률 시험, 펄스 시험, 전단 분석을 통해 온도에 대한 영향을 확인하였다. MFG-220, Finex CS-10GC의 경우, 펄스 시험을 통해 온도 변화에 의한 크로마토그램의 변화를 알아보았다. 실험의 결과 Dow99Ca350, MFG-220과 Finex CS-10GC는 과당과 포도당 각각 최대 1.76, 3.37%의 체류 시간 변화를 보임으로써 온도에 안정적인 경향성을 보였다.

최적설계기법을 이용한 전기자동차용 유도전동기 설계 (Design of Induction Motor for Electric Vehicles using Optimization Technique)

  • 김영관;임강민;염국남;배상호;유영석;유우현
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1996년도 하계학술대회 논문집 A
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    • pp.6-8
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    • 1996
  • Induction Motors are preferred because of their ability to achieve higher power density, efficiency and reliability than permanent DC Motors for Electric Vehicle Drives. This paper describes induction motor design procedure to achieve high power density for EV using nonlinear optimization technique. Objective functions are considered to improve power density and a set of eight design variables is identified. As a numerical example, an induction motor of 15kW, 3 phase and 4 pole is designed.

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발전기 통합제어장치 개발 (A Development of Unified Digital Generator Controller)

  • 유영석;권혁;이상정;이선희;최용실
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1996년도 하계학술대회 논문집 B
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    • pp.1164-1166
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    • 1996
  • This system is an unified Digital Generator Controller. It has an Electronical Generator Sequencer which control the sequence of a generator, an AVR(Automatic Voltage Regulator) which perform the regulation of generator terminal voltage optimally to user's needs, and an Auto Synchronizer, it can switch the power source on from generally used an the generator to load automatically. It also possesses a Battery Charger which charge a storage battery to appropriate voltage level. Here we describe it's configuration, specifications, the way of control, figure, functions and waveforms.

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Improvement in the MIM Sintering Properties of 440C Stainless Steel

  • Soda, Yuji;Hurusaki, Takashi;Aihara, Michitaka
    • 한국분말야금학회:학술대회논문집
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    • 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part 1
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    • pp.217-218
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    • 2006
  • More and more applications or demands for machine parts etc are expected for AISI 440C (hereinafter referred to as "440C") Stainless Steel because of its characteristic features, i.e. high-strength as well as high-corrosion resistance. This research has enabled us to obtain sintered products with good quality even under a wide range of temperature by utilizing the pinning effect of NbC, improving the relevant sintering feature of 440C Stainless Steel in the MIM method.

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인버터구동시 농형 유도전동기의 파라메타 추정 (Parameter estimation of the inverter-driven squirrel cage induction motor)

  • 강세형;안종보;김근웅;김영관
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1992년도 하계학술대회 논문집 B
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    • pp.695-698
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    • 1992
  • When the inverter driven Induction motor is compared with sinusoidal voltage driving, the loss is increased and efficiency in the same output is decreased by the time harmonics in inverter output. These are based on the eddy current on stator and the skin effects of rotor bar current induced from time harmonic. The aim of this paper is to estimate the equivalent circuit parameter of squirrel cage induction motor fed from inverter considering this effects.

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자성웨지 국산화 개발 및 그 적용에 관한 연구 (A Study on Developing the Magnetic Wedge Material and its Application)

  • 최종구;강이국;배병춘;홍성일
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1996년도 하계학술대회 논문집 C
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    • pp.1482-1484
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    • 1996
  • To apply Magnetic wedges to the motor, comparing with not applying, showes its performance change of efficiency increse, reduction of temperature rise, harmonics, and magnetic noise. The motor specification and test condition are 37kW-4P-380V-60Hz,squirrel-cage, three phase induction motor with semiclosed type slots. The result of load test to compare with nonmagnetic wedges showed 1.5% increment of efficiency at 100% load and $8.0^{\circ}C$ decrement of temperature rise at stator coil. And for developing the magnetic wedge matrial, its manufacturing process was setting and TG-DTA, optical microscope, SEM, bending strength and permeability were investigated into the material made of through the process.

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스마트 ESS 전력제어모듈용 3상 PCS 시제품 성능시험 (Performance Test of Three Phase PCS Prototype for smart ESS Power Control Module)

  • 이태승;황동옥;이동주;백석민
    • 전력전자학회:학술대회논문집
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    • 전력전자학회 2015년도 전력전자학술대회 논문집
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    • pp.532-534
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    • 2015
  • 본 연구에서는 'Open Framework 기반 Smart ESS 전력제어 모듈'과 연동을 위해 설계, 제작한 3상 PCS 시제품의 동작 모드별 주요 전기적 특성을 분석하였다. 충전모드에서 운전시 PWM 컨버터의 입력역률, 입력전류 THD 및 전력변환 효율과 방전모드로 운전시 계통으로 주입되는 전류의 역률, THD 및 전력변환 효율을 각각 측정, 분석하였다. 또한 독립운전시 부하량에 따른 PWM 컨버터의 출력전압 THD 및 전력변환 효율을 측정, 분석하였다.

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