• The Journal of the Korea Contents Association
• /
• v.18 no.4
• /
• pp.89-98
• /
• 2018

Due to the increasing global prevalence of dementia, such as Alzheimer disease, there is a growing public health concern about its prevention. The purpose of this study was to conduct a systematic review for a narrative synthesis and critical appraisal of current published research related to dementia prevention programs among Koreans. To conduct a systematic review, the data bases KoreaMed, Riss4u and 9 Nursing Journals were searched using the key words dementia prevention and cognitive function. Articles published between 2000~2014 and related to dementia prevention programs were reviewed. Two hundred-fifty references were searched but only 29 studies met our inclusion criteria to review. We found that dementia prevention programs focused on: exercise, 11 studies (37.9%); multi-therapy, 9 studies (31.0%); and cognitive enhancement activity, 4 studies(13.8%). The majority of studies (n=19, 65.5%) included adults over 65 while two studies targeted adults over 75. The current literature indicates that future research is needed to develop and provide appropriate and effective dementia prevention programs among Korean older adults.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.18 no.1
• /
• pp.66-74
• /
• 2017

This study was aimed to construct a theoretical model for managing persons with early psychosis. We systematically searched SCOPUS, PubMed, RISS, Web of Knowledge, and KoreaMed for related factors to manage persons with early psychosis. Significant terms or phrases for a preliminary structural model were obtained from 19 studies since 2000 regarding the management of persons with early psychosis. Moreover, the content validity for the model was evaluated by 22 professionals. The study results revealed 51 factors for managing persons with early psychosis extracted by meta-analysis, and all factors were divided into 21 medium classification and 8 categories. A theoretical model was constructed with 8 categories, by using the middle range theory of Peplau's Interpersonal Relationships in Nursing. The results suggest that the theoretical model for the management of persons with early psychosis provides a sound theoretical basis for future study.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• v.40
• /
• pp.26.1-26.10
• /
• 2018

Background: This study aimed to evaluate the mechanical, biological, and esthetic stability of a zirconium abutment according to evidence-based dentistry. Main text: An electronic search was performed. Domestic studies were found using the keywords "zirconia abutments" and "zirconium abutment" in KMbase, KoreaMed, and the National Assembly Library, and international studies were found using the same keywords in PubMed. All identified studies were divided by evidence level from the viewpoint of the research type utilizing the evidence-based review manual. A total of 102 domestic studies (with Korean language) were found, and 9 of these studies were selected. In these nine studies, 3 had evidence level 3 and 6 had evidence level 4. A total of 97 international studies (with English language) were found, and 19 were selected. Among these 19 studies, 5 had evidence level 2 and 7 had evidence level 3, whereas the remainder had evidence level 4. According to the studies, zirconium abutments are mechanically, biologically, and esthetically stable, but the evidence level of these studies is low, and the follow-up duration is no longer than 5 years. Conclusions: All examined studies verified the mechanical stability of zirconium abutments for a period no longer than 5 years. Therefore, a long-term clinical observation is needed. Zirconium abutments are thought to be biologically stable, but they are not superior to titanium abutments. As the esthetic stability of such abutments had a low evidence level in the studies that examined here, a much higher evidence level is needed.

• The Journal of the Korea Contents Association
• /
• v.19 no.2
• /
• pp.661-670
• /
• 2019

The purpose of the study was to review the evidence of effects of virtual reality (VR) technology in nursing education. Four databases were searched for articles publised until November 2018 that databases include PubMed, Proquest (nursing and allied health), CINAHL, & RISS. Key word used for search include 'education, nursing', 'simulation', 'skill training', 'virtual reality' and 'VR'. Of 695 papers searched, Seven studies were selected for data analysis. Of seven studies, five studies used quasi-experimental design and two used one group design. There were two studies used VR technology for skill training and five were scenario based VR simulation program. Studies evaluated outcomes including students performance, time spent on practice, self-efficacy and communication ability that most studies reported positive effects while some figures were not statistically significant. The findings of this study provides evidence of nursing education program using VR, however, additional research with rigorously designed studies using systematized measurements for study outcomes are required. In addition, comparison with existing skill training and simulation education should be considered in the future studies.

• The Journal of the Korea Contents Association
• /
• v.19 no.2
• /
• pp.223-230
• /
• 2019

This study aimed to analyze previous studies on cervical cancer preventive education programs for parents. Data from January 2007 to November 2017 were searched via PubMed, Science Direct and CINAHL in foreign search databases, and RISS and Dbpia in domestic search databases. A total of 329 papers were searched, and 7 papers were finally selected based on the selection criteria and the exclusion criteria. Power point(PPT), leaflet, brochure and text messages were used as method for program education and among which, PPT were used the most. As a result of education program effect, it is found that parent's knowledge on HPV and intention for preventive inoculation became increased and rate of actual inoculation indeed higher. This analysis indicates there is a big need for cervical cancer preventive education program developing for parents in Korea and accordingly, various study for programs are expected to be performed.

• The Journal of the Korea Contents Association
• /
• v.19 no.7
• /
• pp.628-637
• /
• 2019

The purpose of this study was to investigate the systematic review and meta analysis the effect of community based rehabilitation on elderly people with mild cognitive impairment by ICF factors. This study used PubMed MEDLINE, Cochrane CENTRAL database from January 2009 to January 2019. As a result, a total of 5 studies were selected. The ICF factor effect size of the community based rehabilitation was 4.77 for physical function and structure, and 6.17 for activity and participation. The results of this study showed that the effect of community based rehabilitation of the elderly with mild cognitive impairment is effective on physical function, structure, activities and participation.

• Journal of Korean Medicine Rehabilitation
• /
• v.33 no.2
• /
• pp.19-32
• /
• 2023

Objectives The purpose of this study is to systematically review the degree of pain and function improvement in acupuncture treatment for patellofemoral pain syndrome (PFPS). Methods Randomized controlled trials (RCTs) were searched from Medline/PubMed, Cochrane Library, Embase, WanFang Data, China National Knowledge Infrastructure (CNKI), Citation Information by NII (CiNII), Koreanstudies Information Service System (KISS), ScienceON, KoreaMed, and Korean Medical Database (KMbase). The methodological quality of selected RCTs' were evaluated according to Cochrane RoB2 tool. Results Total of 158 studies were identified and 7 RCTs were selected for systematic review. Frequently used evaluation method were visual analogue scale and Kujala scores. All studies showed significant effect on pain reduction and knee function between before and after treatment, but showed partial significance between the intervention and control group. Conclusions Research showed that acupuncture treatment is an effective treatment for improving the pain and function of PFPS, but it is difficult to conclude that it has a significant effect compared to other treatments. Selected studies included subjective evaluation indicators and the total of selected studies were small, so the interpretation of the results is limited. Also most of the included studies are evaluated to have some concerns of bias. Therefore, subsequent research should continously be done in more objective and systematic method.

• Archives of Plastic Surgery
• /
• v.51 no.3
• /
• pp.304-310
• /
• 2024

Background Hidradenitis suppurativa (HS) is associated with a high prevalence of psychiatric disorders. However, no studies examine how psychiatric disorders influence surgical and financial outcomes. This study aimed to assess impact of a psychiatric diagnosis on patients treated for HS. Methods Patients with HS were retrospectively identified at a single institution from 2010 to 2021. Cohorts were stratified by the presence of a psychiatric disorder. Demographics, comorbidities, and disease characteristics were collected. Outcomes assessed included the procedural interventions and emergency department (ED) visits. Financial distress was assessed via the COST-FACIT Version 2 survey. Results Out of 138 patients, 40 (29.0%) completed the survey of which 19 (47.5%) had a preexisting psychiatric diagnosis. No demographic differences were found between cohorts. Mean follow-up was 16.1 ± 11.0 months. The psychiatric cohort had a higher median number of surgeries received (7.0 vs. 1.5, p < 0.001), a higher median number of ED visits (1.0 vs. 0, p = 0.006), and a similar hospital length of stay (p = 0.456). The mean COST-FACIT score of the overall study population was 19.2 ± 10.7 (grade 1 financial toxicity). The psych cohort had a lower mean COST-FACIT score (16.8 vs. 21.3, p = 0.092) and reported greater financial hardship (3.3 vs. 1.7, p < 0.001). On multivariate analysis, a psychiatric diagnosis was predictive of lower credit scores, more ED visits, and a higher number of surgeries. Conclusion Preexisting psychiatric conditions in patients with HS are associated with increased health care utilization and surgical intervention with substantial financial distress. Plastic surgeons should be cognizant of such comorbid disorders to facilitate holistic care addressing all patient needs.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.19
• /
• pp.8331-8335
• /
• 2014

Background: Previous studies accessing the association of CYP2C19 with outcomes of patients using tamoxifen for breast cancer have yielded conflicting results. The aim of this meta-analysis is to obtain a more precise estimate of effects of CYP2C19 polymorphisms and to clarify their effects on survival of the breast cancer patients using tamoxifen. Materials and Methods: A systematic search of PubMed and Embase was performed, comparing patients with or without $CYP2C19^*2$ and $CYP2C19^*17$, relevant articles searched for. The following outcomes were included from the eligible studies: disease-free survival (DFS) and overall survival (OS), expressed by hazard ratios (HR) with corresponding 95% confidence interval (CI). Subgroup analysis by genotypes was also performed. Pooled estimates were calculated using random-effect model in accordance to the heterogeneity. Results: Six studies met the inclusion criteria. The integrated OR on the association between CYP2C19 and DFS, calculated by the random-effect model, was 0.54 (95%CI=0.34-0.84, p=0.013). Subgroup analysis showed that both $CYP2C19^*2$ and $CYP2C19^*17$ were associated with increased survival. The pooled results of two studies for OS were OR=0.46 (95%CI=0.21-1.01, p=0.233). Conclusions: This meta-analysis suggests that the $CYP2C19^*2$ and $CYP2C19^*17$ genotypes are associated with increased survival in breast cancer patients using tamoxifen.

• The Korean Journal of Nuclear Medicine
• /
• v.14 no.1
• /
• pp.1-8
• /
• 1980

Serum TSH levels were measured by radioimmunoassay before and after intravenous administration of synthetic thyrotropin-releasing hormone (TRH) to 15 normal subjects and 55 patients with primary thyroid disease (14 patients with euthyroidism, 24 patients with thyrotoxicosis and 17 patients with hypothyroidism) to evaluate pituitary TSH reserve and its diagnostic availability. The observed results were as follows. 1. In normal subjects, serum TSH responses to synthetic TRH were $3.2{\pm}1.0$ at 0min (baseline TSH level), $8.0{\pm}4.0$ at 10min, $11.7{\pm}5.0$ at 20min, $13.7{\pm}7.1$ at 30min, $9.7{\pm}5.0$ at 60min., $5.2{\pm}2.0$ at 120min. and $3.6{\pm}0.4{\mu}U/ml$ at 180 min. Serum TSH peaked at $20{\sim}30$ minutes and returned nearly to baseline at 180minutes. 2. In euthyroid group, serum TSH responses to synthetic TRH were $3.3{\pm}1.6$ at 0min, $8.6{\pm}8.0$ at 10min, $10.9{\pm}8.5$ at 20min, $12.5{\pm}8.4$ at 30min, $9.0{\pm}5.9$ at 60min, $5.6{\pm}2.6$ at 120min and $3.5{\pm}1.3{\mu}U/ml$ at 180min. No significant difference revealed between euthyroid group and normal subjects (p>0.05). 3. In hyperthyroid group, serum TSH responses to synthetic TRH were $1.5{\pm}0.6$ at 0min, $2.2{\pm}0.8$ at 10min., $2.3{\pm}1.0$ at 20min., $2.4{\pm}1.5$ at 30min., $2.1{\pm}1.1$ at 60min., $1.9{\pm}0.2$ at 120min. and $1.5{\pm}0.8{\mu}U/ml$ at 180min., No response to TRH showed. 4. In hypothyroid group, mean values of serum TSH response to synthetic TRH were 42.0 at 0min., 60.6 at 10min., 124.8 at 20min., 123.0 at 30min., 101.6 at 60min., 64.3 at 120min. and $15.5{\mu}U/ml$ at 180 min., Patients with primary hypothyroidism showed an exaggerated TSH response to synthetic TRH despite their high basal TSH. 5. Side effects attending synthetic TRH administration were transient nausea (59.0%), desire to micturate (59.0%), feeling of flushing(19.7%), dizziness (45.9%), metallic taste (9.8%) and headache (19.7%). Any side effect didn't show in 16.4%. These symptoms began almost immediately after TRH intravenous injection and lasted several minutes, and not related to dose or response in the person experiencing it.