• Transactions of the Korean Society of Mechanical Engineers A
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• v.34 no.12
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• pp.1793-1803
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• 2010

The weighting method and goal programming require weighting factors or target values to obtain a Pareto optimal solution. However, it is difficult to define these parameters, and a Pareto solution is not guaranteed when the choice of the parameters is incorrect. Recently, the Mahalanobis Taguchi System (MTS) has been introduced to minimize the Mahalanobis distance (MD). However, the MTS method cannot obtain a Pareto optimal solution. We propose a function called the skewed Mahalanobis distance (SMD) to obtain a Pareto optimal solution while retaining the advantages of the MD. The SMD is a new distance scale that multiplies the skewed value of a design point by the MD. The weighting factors are automatically reflected when the SMD is calculated. The SMD always gives a unique Pareto optimal solution. To verify the efficiency of the SMD, we present two numerical examples and show that the SMD can obtain a unique Pareto optimal solution without any additional information.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.5
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• pp.1270-1276
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• 2010

In this paper, Quad-Band small antenna for GSM850, GSM900, DCS1800, DCS1900 is designed and fabricated. The antenna achieved the size reduction of over 67.9 % than the conventional PIFA(Planar Inverted-F Antenna) by using a MD(Magneto-Dielectric) material. A simple feeding microstrip line is used to feed the antenna from a $50{\Omega}$ coaxial line, which is capacitively coupled to the grounded patch structure for broadband characteristics. The impedance bandwidth the proposed antenna shows good results as broadband characteristics of 1341 MHz (801 ~ 2142 MHz) in VSWR < 3 (${\leq}\;-6\;dB$) and the gain is -6.67 ~ 4.25 dBi in the operating frequency.

• Journal of Intelligence and Information Systems
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• v.15 no.4
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• pp.53-64
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• 2009

This paper presents a performance evaluation of shape descriptors for gait analysis in case of silhouette sequence images. We used moment descriptors(MD), Fourier descriptors(FD) and Zernike descriptors(ZD) as a shape descriptor. To evaluate their performance, we firstly defined the performance index, that is, AI(asymmetry index) and PI(periodic index) based on the periodic property of the gait images. This is why they are represented by periodic parameters due to periodic gait images. This index means that how the shape is represented periodically. According to these indexes, we evaluated the data sets with periodic images, downloaded from internet. The results showed that Zernike descriptors had better performance of AI = 1.09 and PI = 2.21 than others. And in case of FD and ZD, it's efficient to implement the gait analysis with 5~10 parameters.

• Journal of Sericultural and Entomological Science
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• v.35 no.2
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• pp.129-133
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• 1993

The 44Md plasmid of Bacillus thruingiensis var. kurstaki HD-1(B. t k HD-1) was partially digested with Sau3AI and the fragments were cloned into E. coli HB101 on vector pBR322. Of 2, 950 clones with a recombinant pBR322, only one clone KC1 was determined to have the gene for crystal toxic proteins from the 44Md plasmid of B. t k HD-1 at the BamHI site of pBR322. The recombinant pBR322 was named pKC1 and its molecular size was 12kb. The KC1 produced a protein which was toxic to the silkworm and antigenically similar to the crystal toxic protein of B. t k HD-1. Also, electrophoretic mobility of the KC1 protein was apparently the same as that of the crystal toxic protein of B. t k HD-1.

• Journal of the Semiconductor & Display Technology
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• v.13 no.2
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• pp.53-56
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• 2014

In this work, we investigate the operational properties of this proposed device in detail via classical MD simulations. The bi-stability of the GNF(Graphene Nano-flake) shuttle encapsulated in bi-layer GNR could be achieved from the increase of the attractive energy between the GNRs when the GNF approached the edges of the GNRs. This result showed the potential application of the nano-electromechanical GNR memory as a NVRAM.

• Korean Journal of Veterinary Pathology
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• v.6 no.2
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• pp.101-104
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• 2002

닭의 전신장기에 림프종 발생이 특정인 마렉병(Marek's disease; MD)은 림프구성 백혈병(Lymphoid leukosis; LL)과 병리학적 소견이 매우 유사하여 감별이 요구된다. 마렉병 바이러스(Marek's disease virus; MDV)는 질병초기에서 후기에 이르기까지 모낭상피세포에 세포용해성 감염을 지속적으로 일으킨다. 세포용해성 감염이 있는 모낭상피세포는 변성내지 괴사되어 있고 핵내봉입체가 관찰된다. 또한 세포용해성 감염이 있는 모낭상피세포 바로 밑의 진피와 깃털 수질(feather pulp)내의 혈관주위에 림프구 침윤이 관찰된다. 이러한 피부병변은 MD의 특징적인 병변들로서 LL과 감별할 수 있는 결정적인 단서이다. 본 고에서는 MD에 관한 전반적인 것과 특히 MD 진단을 위한 피부병변의 유용성에 대해서 자세히 논하고자 한다. 양계산업에 문제를 야기하고 있는 림프구 증식성 종양은 크게 마렉병(Marek’s disease; MD)과 백혈병(Lymphoid leukosis; LL)이 있다. 이들 질환의 원인체들이 분리되기 전까지는 이들 질병들은 발병부위에 따라 질병명을 붙였다. 즉, 내부장기냐 근육에 발생한 것은 visceral lymphomatosis, 피부에 발생한 것은 skin leukosis, 말초신경의 병변은 poly­n neuritis, neuritis, neurolymphomatosis gallinarum, range paralyis로 불리었다. 또한 눈에 발생한 것은 blindness, gray eye, iritis, uveitis, ocular lymphomatosis라고 불리었다. 1961년에 Biggs는 이러한 림프구 증식성 질병을 마렉병과 백혈병 으로 분류하자는 제안을 하였고, 드디어 1960년대 중반에 림프구 증식성 병변 중의 일부에서 herpesvirus가 분리되어서 Biggs가 제안한 병명인 마렉병을 본격적으로 사용하게 되었다. MD는 마렉병 바이러스(Marek’s disease virus; MDV)가 원 인제로서 닭에 전염성이 강한 염증성에서 종양성의 병변을 내부장기, 피부, 근육, 안구, 중추신경계, 말초신경계 등에 일 으킨다. MDV는 림프종을 유발하기 때문에 처음에는 사람에서 림프종을 유발하는 Epstein-Bar 바이러스와 관련이 있을 것으로 생각되어 gamma-herpesvirus로 분류되었지만, MDV의 게놈 구조와 세포배양에서 빠르게 성장한다는 점 때문에 지금은 alpha-herpesvirus로 재분류 되었다. MDV는 바이러스 중화시험과 한천 겔 침강법에 의해서 3개의 혈청형으로 분류 된다. 혈청형 1은 종양원성 바이러스와 종양원성 바이러스의 계대배양에 의한 약독주가 있다. 혈청형 2는 자연적으로 발 생하는 비종양원성 닭의 MDV이고, 혈정형 3은 바종양원성 칠면조 herpesvirus (HVT)이다. 림프종을 유발하는 MDV 감염은 4개의 과정, 즉 초기 세포용해성 감염, 잠복감염, 후기 세포용해성 감염, 마지막으로 종양화로 나눌 수 있다. 감염의 경로를 보면, 흡입된 MDV는 폐의 대식세포에 감염한 후 전선 장기로 MDV를 전파 시킨다. 특히, 흉선, F냥, 비장 등의 림프구에 초기 세포용해성 감염을 일으키는데, B 림프구가 주로 감염된다. 세포용해성 감염음 방어하기 위해 몰려든 T 림프구가 활성화가 되면, T 세포도 감염되게 된다. 잠복감염은 여러 가지 사이토카인 등 을 포함한 면역반응에 의해서 일어나며, 이 때 잠복감염된 세포는 특히 혈중의 T 세포라고 한다. 혈중 MDV 감염세포 는 피부 모낭상피세포, 선장 등 상피세포 유래의 조직에 MDV를 전파 시켜서 이들 조직에서 후기 세포용해성 감염이 일어나게 한다. 후기 세포용해성 감염을 유발하는 것은 이러한 MDV가 감염된 혈중 림프구라는 증거는 혈중의 세포 외에는 감염성 바이러스가 없기 때문이다. 후기 세포용해성 감염이 있는 후 육안적 혹은 현미경적으로 검출이 가능한 림프종이 여러 장기에서 관찰된다. MDV가 감염되면 병변 발생부위에 따라서 다양한 임상증상이 발생한다. 즉 내부장기에 병변이 있을 경우는 침울, 체중감소, 산란율 저하 등이 발생하며, 신경계는 발생부위별 신경증상이 일어난다. 이러한 장기나 조직에서는 육안적으로 백색에서 회백색의 종양성 병변이 관찰된다. 말초신경에 병변이 발생한 경우에는 특히 좌골신경 및 신경총에서 호발하는데, 이들 조직은 편측성 혹은 양측성으로 종창되어 있다. 안구는 간혹 육안적으로 식별이 가능한 홍채 퇴색 및 증식 병변이 관찰된다. 피부형 MD는 특히 육용계에서 문제가 되고 있으며, 산란계의 내장형 MD가 발생한 경우에도 피부를 자세히 설펴보면 피부형 MD를 간혹 관찰할 수 있다. 피부형 MD는 모낭주위에 원형의 결절형태로 발생하는데, 이들 병변이 커지면 바로 옆의 병변과 융합 되어 큰 결절을 형성하기도 한다. (중략)

• Journal of Nutrition and Health
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• v.35 no.2
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• pp.183-191
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• 2002

The purpose of this study was to investigate the effect of dietary mushroom powder on blood glucose levels, seam lipid levels, glucose 6-phosphtase (G6Pase), thiobarbituric arid reactive substance (TBARS) and glutathione enzymes in diabetic rats treated with streptozotocin (STZ). Four groups of rats (Sprague-Dawley male rats, 180-200 g) were fed as follows: normal rats were fed a control diet (C), diabetic rats were file a control diet (CD), normal fats were fed a mushroom powder diet (M), and diabetic rals were find mushroom powder diet (MD). Diabetes was induced by single injection of streptozotocin (60 mg/kg B.W.). The animals were fed ad libium each of the experimental diets for five weeks. Food and water intake was determined every day. Blood glucose and serum total cholesterol levels were determined every week. After five weeks, the rats were sacrificed and blood glucose, serum total cholesterol, triglyceride levels and glutathione enzymes were measured. HDL-cholesterol levels were analyzed and LDL-cholesterol concentrations were calculated by equation. There was body weight loss in the diabetic rats, but the MD group showed less body weight loss than the CD group. Blood glucose and serum total cholesterol level of the MD group were lower than those of the CD group (p < 0.05). Also, serum total cholesterol of the M group was lower than that of the C group (p < 0.05). But the serum triglyceride level of the diabetic rats (CD and MD) was higher than that of the normal rats (C and M). However, there was no significant difference between the control diet group and the mushroom diet group. Serum HDL-cholesterol levels of the C group and CD group were higher than that of the M group (p < 0.05), and the MD group was not significantly different. But the serum LDL-cholesterol levels of the M group were lower than those of the C group (p < 0.05). Activity of hepatic microsomal G6Pase significantly increased in the CD and MD, reaching levels higher than those of the C and M groups. Hepateic gutathione S-transferase (GST, glutathione reductase (GR) and glutathione peroxidase (GPX) activity was not significant. But renal GST, GR and GPX activity in the MD group was lower than that of the CD group (p < 0.05). These results suggest that dietary mushroom reduces renal disorders such as oxidation and aging of tissue. In conclusion, dietary mushroom groups reduced blood glucose and cholesterol levels in STZ-induced diabetic rats and renal glutathione enzymes activity was averted in diabetic rats.

• Journal of the Korean Institute of Intelligent Systems
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• v.9 no.4
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• pp.420-425
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• 1999

The maximum demand controller is an electrical equipment installed at the consumer side of power system for monitoring the electrical energy consumed during every integrating period and preventing the target maximum demand (MD) being exceeded by disconnecting sheddable loads. By avoiding the peak loads and spreading the energy requirement the controller contributes to maximizing the utility factor of the generator systems. It results in not only saving the energy but also reducing the budget for constructing the natural base facilities by keeping thc number of generating plants ~ninimumT. he conventional MD controllers often bring about the large number of control actions during the every inteyating period and/or undesirable loaddisconnecting operations during the beginning stage of the integrating period. These make the users aviod the MD controllers. In this paper. fuzzy control technique is used to get around the disadvantages of the conventional MD control system. The proposed MD controller consists of the predictor module and the fuzzy MD control module. The proposed forecasting method uses the SOFM neural network model, differently from time series analysis, and thus it has inherent advantages of neural network such as parallel processing, generalization and robustness. The MD fuzzy controller determines the sensitivity of control action based on the time closed to the end of the integrating period and the urgency of the load interrupting action along the predicted demand reaching the target. The experimental results show that the proposed method has more accurate forecastinglcontrol performance than the previous methods.

• Advances in environmental research
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• v.5 no.2
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• pp.79-94
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• 2016

In order to evaluate the contamination and health risk, levels of six hazardous elements i.e., Cr, Ni, Cu, As, Cd and Pb in soils of 12 different land-uses were measured. The average concentration of Cu, Cr, Ni, Pb, As and Cd in soils were 267, 239, 206, 195, 58 and 16 mg/kg, respectively. Levels of each metal exceeded the environmental action level for soils, which could pose significant risk to human. The metal concentrations were subsequently used to establish hazard indices (for adults and children) where the 5th and 95th percentile values were used to derive the hazard index through different exposure pathways (ingestion, dermal contact and inhalation). Considering the total exposure through each of the three pathways, the hazard index elucidates that there was a potency of non-cancer risk at most of the sites for both the adults and children. The findings of this study suggested that different land-use soils were severely contaminated with hazardous elements and attention is needed on the potential health risks to the exposed inhabitants.

• Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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• 2005.11a
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• pp.45-53
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• 2005

A novel method for evaluating the anisotropy of the deterministic features in a stochastic 2D data is introduced. The ability of the wavelet transform for the identification of the abrupt discontinuities could be used to characterize the boundary of the deterministic area in a 2D stochastic data, such as flocs in paper structure. The one-dimensional wavelet transform with a small-scale range in MD and CD could quantify the amount of the edge in both directions, depending on the intensity of each floc. The flocs that are aligned in the MD direction result in a higher value of local wavelet energy in the CD direction. Therefore, the ratio of the total wavelet energy in CD and MD directions can be used as a new anisotropy index. This index is a measure of the floc-orientation and can provide an excellent tool to obtain the orientation distribution and the major oriented angle of flocs. Various simulated images and real stochastic data such as local gloss variation of printed image and formation image, have been tested and the results show this analysis method is very reliable to measure the anisotropy of the deterministic features.