• Title/Summary/Keyword: MD-2

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Production of Bone Broth Powder with Spray Drying Using Three Different Carrier Agents

  • Haluk, Ergezer;Yeliz, Kara;Orhan, Ozunlu
    • Food Science of Animal Resources
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    • v.38 no.6
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    • pp.1273-1285
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    • 2018
  • The aim of this study is to determine the some physicochemical (proximate composition, pH and $a_w$ values) and reconstitution (wettability, dispersibility and solubility index (SI)) properties of spray-dried bone broth powder (BBP) along with the effects of the addition of different carrier agents. Subsequently, the powdered products were stored to determine the storage stability (pH, lipid oxidation, color, browning index) for 3 mon at $-18^{\circ}C$. For this purpose, firstly marrow-containing bones (Os femur and Os humerus) have been boiled to get the bone broth. Three different emulsions were respectively prepared (1) 20% maltodextrin (MD) added BBP, (2) 20% whey powder isolate (WPI) added BBP and (3) 10% MD and 10% WPI added BBP and the emulsions were dried using a spray-dryer with $185^{\circ}C$ inlet and $95^{\circ}C$ outlet temperature. The proximate composition and reconstitution properties of BBP were found statistically different (p<0.05) depending on the use of different carrier agents. MD added BBP showed uniform and smooth morphology. The color, browning index, thiobarbituric acid reactive substances (TBARS) and pH values of BBP significantly changed (p<0.05) during storage. In conclusion, both the results of physicochemical and storage period analyses showed that the most suitable encapsulation material in the production of the bone broth powder is MD.

Effect of Citrus macroptera Fruit Pulp Juice on Alteration of Caspase Pathway Rendering Anti-Proliferative Activity against Ehrlich's Ascites Carcinoma in Mice

  • Hasan, Md. Mahmudul;Islam, Md. Shihabul;Hoque, Kazi Md. Faisal;Haque, Ariful;Reza, Md Abu
    • Toxicological Research
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    • v.35 no.3
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    • pp.271-277
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    • 2019
  • Citrus macroptera (Rutaceae) has long been used in folk medicine in Bangladesh. Considering the folkloric context, this study was aimed to scrutinize anti-proliferative activity of C. macroptera fruit pulp juice (CMFPJ) against Ehrlich's ascites carcinoma (EAC). The anti-proliferative capacity of CMFPJ was investigated and confirmed primarily using MTT assay. In vivo anti-proliferative aptitude of CMFPJ was investigated with 25, 50, and 100 mg/kg/day intraperitoneal (i.p.) treatment. Anti-proliferative efficacy of CMFPJ was assessed based on EAC growth inhibition. CMFPJ inhibited EAC growth in vitro in a dose-dependent manner. And the percentages of in vivo EAC growth inhibition were 19.53, 49.2, and 68.9% at 25, 50, and 100 mg/kg CMFPJ respectively. CMFPJ significantly induced expression of apoptosis regulatory genes caspase-8, caspase-9, cytochrome-c, and caspase-3. This considerable anti-cancer activity was perhaps due to combinatorial effect of lectin, polyphenols, and flavonoids present in CMFPJ.

A STUDY OF DENTAL CROWDING AND ITS RELATIONSHIP TO MANDIBULAR INCISOR SHAPE BY MODEL ANALYSIS IN ADOLESCENTS (청소년 석고 모형 분석에 의한 하악절치 형태와 치아밀집의 상관관계에 관한 연구)

  • Surh, Jeong-Eun;Baik, Hyoung-Seon
    • The korean journal of orthodontics
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    • v.25 no.5 s.52
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    • pp.593-604
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    • 1995
  • Mandibular incisor crowding is one of the most common features of malocclusion and is interesting characteristic in view of relapse and stability after orthodontic treatment. There are many potential factors in the etiology of lower anterior crowding. The tooth size variation is one of them, but biologic significance for the faciolingual width of the teeth has been overlooked. Peck and Peck reported that persons with ideal mandibular incisor alignment were shown to have incisor with smaller mesiodistal and larger faciolingual dimensions than persons with incisor crowding. On the basis of these findings they suggested MD/FL index as a clinical guideline for the assessment for lower incisor crowding. The present study was undertaken to examine the relationship between mandibular incisor crowding and mandibular incisor dimension, and determine their correlation with arch length discrepancy. 154 dental casts of people from 11 to 17 years of age were made, and were divided into normal group with irregularity index less than of 1, and crowding group with irregularity index greater than 1.The casts were measured and analyzed statistically. The results were as follows. 1. The mean mesiodistal width for mandibular incisor was larger in crowding group, and has significant difference in central inciosr measurement. There are no significant differences in the faciolingul width and MD/FL index. 2. Irregularity index has significant correlation coefficients with mesiodistal width and MD/FL index for mandibular incisor in crowding group, but no correlation with faciolingual width. It also has correlation with maxillary and mandibular arch length discrepancy, total tooth material, mandibular intercanine width, and mandibular inter first premolar width. 3. Upper and lower arch length discrepancy have significant correlation with mesiodistal width of mandibular incisor and overbite, but have no correlation with faciolingual width. Lower arch lenth discrepancy has significant correlation with MD/FL index for mandibular incisor and upper arch length discrepancy has correlation with MD/FL index for mandibular lateral incisor. 4. Significant differences were observed between normal and crowding group for the mandibular arch length discrepancy and overbite.

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A Molecular Dynamics Simulation Study of Ranciéite-takanelite Solid Solution Crystal Structures (란시아이트-다카네라이트 고용체 결정구조에 대한 분자동역학 시뮬레이션 연구)

  • Han, Suyeon;Kwon, Kideok D.
    • Korean Journal of Mineralogy and Petrology
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    • v.33 no.1
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    • pp.19-28
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    • 2020
  • Ranciéte is a hexagonal phyllomanganate mineral containing random Mn(IV) vacancies with hydrated Ca2+ cations charged balanced as interlayer cations. Its Mn2+ analogue is called takanelite, and ranciéite and takanelite are regarded as end-members of a solid solution series of (Ca2+,Mn2+)Mn4O9·nH2O. Because the minerals are found as very small particles associated with other minerals, the crystal structures of the solid solution series have yet to be defined. In this research, we conducted classical molecular dynamics (MD) simulations of ranciéite and takanelite by varying the Mn2+/Ca2+ interlayer cation ratio to find relations between the interlayer cations and mineral structures. MD simulation results of chalcophanite group minerals are compared with experimental results to verify our method applied. Then, lattice parameters of ranciéite and takanelite models are presented along with detailed interlayer structures as to the distribution and coordination of cations and water molecules. This study shows the potentials of MD simulations in entangling complicated phyllomanganates structures.

Clinical Features of Symptomatic Meckel's Diverticulum (증후성 멕켈 게실의 임상적 고찰)

  • Lee, Young Ah;Seo, Ji Hyun;Youn, Hee Sang;Lee, Gyeong Hun;Kim, Jae Young;Choi, Gwang Hae;Choi, Byung Ho;Park, Jae Hong
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.9 no.2
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    • pp.193-199
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    • 2006
  • Purpose: The proper diagnosis of Meckel's diverticulum (MD) is difficult and delayed because of the variety of clinical manifestations. We reviewed clinical characteristics of symptomatic MD to facilitate early detection. Methods: We analyzed retrospectively the clinical manifestations, diagnostic tools, histopathological findings, and operative findings in 58 patients with symptomatic MD. Results: The male to female ratio was 2.8 : 1. The most common symptom of MD was bleeding. Others symptoms included: vomiting, abdominal pain, irritability, abdominal distension and fever in the order of frequency. The clinical manifestations of symptomatic MD were lower gastrointestinal bleeding, intestinal obstruction, perforation, diverticulitis and hemoperitoneum, in the order of frequency. The causes of intestinal obstruction were intussusception, internal hernia, band, volvulus, invagination, in the order of frequency. Seventy five percent of patient with MD were diagnosed prior to 5 years of age. The most frequently used diagnostic tool was the Meckel's scan. The diverticulum was located 2 cm to 120 cm proximal to the ileocecal valve. The length of the diverticulum ranged from 1 cm to 10 cm and 94% were less than 5 cm. The most common ectopic tissue found in the MD was gastric mucosa. Ileal resection was more frequently performed than diverticulectomy. Conclusion: In cases of unexplained gastrointestinal bleeding, obstruction and repeated intussusception, the meckel's scan, ultrasound and computed tomography shoud be considered to rule out MD, and if clinically necessary, an exploratory laparotomy when needed.

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Ergonomic Evaluation of Console Chairs for a Weapon Locating Radar

  • Lee, Baekhee;Jung, Kihyo;Jeong, Jineun;Kim, Jinman;Hong, Wongi;Park, Seikwon;You, Heecheon
    • Journal of the Ergonomics Society of Korea
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    • v.33 no.2
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    • pp.97-108
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    • 2014
  • Objective:The present study is intended to evaluate the usability of a console chair for a weapon locating radar by comparing with different kinds of chair design. Background: Console chairs need to be ergonomically designed to reduce physical workload of operators and improve mission capability; few studies have been reported which systematically evaluate usability of military console chairs. Method: Ergonomic design of a console chair, a bus seat, and an office chair was evaluated in terms of headrest, seatback, seatpan, armrest, and controller on a 7-point scale. Ten males in their 20s and 30s were recruited considering the demographic characteristics of console operators. Results: The satisfaction scores of the console chair for headrest, seatback, and seatpan were significantly higher than those of the bus seat (mean difference [MD] = 0.9) and office chair (MD = 1.3). Meanwhile, the satisfaction scores of the console chair for armrest and controller were significantly lower than those of the office chair (MD = -1.4) and bus seat (MD = -2.2). Conclusion: The armrest and controller of the console chair needs ergonomic improvements for better comfort. Application: The evaluation results of the console chair would be of use for ergonomic console chair design.

Improving hydration in elite male footballers during a national team training camp - an observational case study

  • Mohr, Magni;Nolsoe, Eli Leifsson;Krustrup, Peter;Fatouros, Ioannis G.;Jamurtas, Athanasios Z.
    • Korean Journal of Exercise Nutrition
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    • v.25 no.4
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    • pp.10-16
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    • 2021
  • [Purpose] The purpose of this study was to (i) assess hydration levels in elite male football players during a national team training camp before and during qualifying matches, (ii) evaluate the effect of coaching strategies for hydration based on feedback from hydration monitoring, and (iii) assess possible relationships between hydration status and training load or wellness markers. [Methods] Thirty-one male players (age 27±4 yrs; height 185±6 cm; weight 82.9±6.7 kg; body fat 10.4±2.3%) representing a national team from the Union of European Football Associations (UEFA) participated. The players were studied during three different national team training camps related to the UEFA Nations League tournament. Urine specific gravity (USG) was measured to assess hydration status. During all camps, the players were actively coached on improving strategies for hydration and given individual feedback on their test results. The training load was measured using GPS technology, and wellness questionnaires were completed. [Results] USG decreased progressively and significantly (p<0.005) during camp 1 and hydration status improved over the three camps, with fewer dehydrated and more well-hydrated players identified during the last part of camp 3. Significantly (p<0.05) higher USG values were observed 2 days prior to a match (MD-2) than on match day (MD); consequently, 52% of the players were dehydrated on MD-2 and only 6% on MD. No correlations were observed between hydration status and training load or wellness markers. [Conclusion] Dehydration is a challenge in elite male football, but continuous monitoring of hydration status and coaching on hydration strategies can lead to major improvements and reduce the degree of dehydration.

HIGH RESOLUTION $HC_3N$ OBSERVATIONS TOWARD THE CENTRAL REGION OF SAGITTARIUS B2

  • CHUNG HYUN SOO;OHISHI MASATOSHI;MORIMOTO MASAKI
    • Journal of The Korean Astronomical Society
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    • v.27 no.1
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    • pp.1-11
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    • 1994
  • We have observed the emission of $HC_3N$ J=4-3, 5-4,10-9 and 12-11 transitions toward the Sgr B2 central region in an area of $150'\times150'$ with resolutions of 16'-48'. The intensities and central velocities of line profiles show significant variations with positions. In contrast to the intensities of the low J-level transitions which gradually increase from the central source toward the outside region, the $HC_3N$ emission of the high J-level transition become stronger toward 'the central radio continuum source MD5. Systematic change in the radial velocity of each line profile occurs along north-south direction. There are a few peaks in most line profiles, and these indicate that there are multiple velocity components along the line of sight. Distributions of excitation temperature and column density which were estimated from the excitation calculations show the existence of a small $(1\times2pc),\;hot\;(T_{ex}>50K)$ core which contains two temperature peaks at-15' east and north of MD5. The column density of $HC_3N\;is\;(1-3)\times10^{14}cm^{-2}$ Column density at distant position from MD5 is larger than that in the central region. We have deduced that this 'hot-core' has a mass of 105M 0, which is about an order of magnitude larger than those obtained by previous studies.

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Factors Influencing the Adoption of Cloud Computing in Healthcare Organizations: A Systematic Review

  • Qiu, Hong;Shen, Beimin;Wang, Yuhao;Mei, Yu;Gu, Wenjie
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.16 no.12
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    • pp.3960-3975
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    • 2022
  • To analyze and compare the most influencing factors on cloud computing adoption (CCA) in the healthcare organization, a systematic review and meta-analyses of studies was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and Cochrane collaboration recommendations. A search of PubMed, ScienceDirect, Springer, Wiley Online, and Taylor & Francis Online digital libraries (From inception to January 19, 2022) was performed. A total of 17 studies met the defined studies' inclusion and exclusion criteria. Statistical significance difference favoring most influencing factors on CCA were (MD 0.76, 95% CI -1.48 - 3.01, p <0.00001, I2 = 90%), (MD 1.40, 95% CI -4.76 - 7.55, p < 0.00007, I2 = 97%) (MD 0.17, 95% CI -2.69 - 3.03, p<0.00001, I2 = 96%) for technology vs. organizational, technology vs. environmental and business vs. human factors, respectively. Organizational and environmental factors had greater impacts on CCA compared with technological factors. Moreover, business factors were more influential than the human factors.

The Effects of Adult Nursing Education on the Critical Thinking Disposition, Learning Commitment, and Learning Satisfaction of Nursing Students Using the Havruta Learning Method (하브루타 학습법을 활용한 성인간호학 교육이 간호대학생의 비판적 사고성향, 학습몰입 및 학습만족도에 미치는 영향)

  • Lim, So-Hee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.7
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    • pp.547-554
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    • 2019
  • Havruta is the best teaching and learning method for developing the process of thinking, and it is a method of education centered on a range of student activities. This study examined the effects of adult learning nursing education using the Havruta learning method on the critical thinking disposition, learning commitment, and learning satisfaction. Data collection was carried out from September to December, 2017 in 96 second grade nursing college students attending a university in U city. The data were analyzed using descriptive statistics, ${\chi}^2-test$, t-test, and two-way repeated ANOVA using the SPSS WIN 23.0 program. The critical thinking disposition, learning commitment, and learning satisfaction were similar in the experimental group, who performed the adult nursing education using the Havruta learning method, and the control group. On the other hand, after the adult nursing education using the Havruta learning method, the critical thinking tendency (md=.14, p=.045), learning commitment (md=.27, p=.025), learning satisfaction (md=.30, p=.031) increased significantly. Therefore, adult nursing education using the Havruta learning method is an effective program to improve the critical thinking disposition, learning commitment, and learning satisfaction of nursing college students.