• 대한전자공학회논문지SP
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• 제37권2호
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• pp.15-20
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• 2000

본 논문에서는, 움직임 벡터와 보상 블록을 이용한 분류기를 제안하고, 이 분류기로써 MCD(motion compensated difference) 블록을 CVQ(classified vector quantization)하는 새로운 MCDI(motion compensated difference image) 부호화 방법을 제안하였다. MCD 블록의 분산은 움직임 벡터의 크기뿐만 아니라 보상 블록의 분산과도 밀접한 관계가 있으므로, 이 특성들을 이용하여, 새로운 분류기를 제안하였다. 제안한 방법은 서브 코드북(sub-codebook)을 선택하는 분류기에 대한 부가 정보가 필요 없으면서, 모의 실험 결과 분류 비트가 필요한 기존의 방법에 비해 제안한 방법이 좋은 성능을 나타내었다.

• 약학회지
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• 제56권2호
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• pp.99-107
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• 2012

The protective effect of AI-1367 (Alnus japonica extract) on liver injury was investigated. Primary rat hepatocyte intoxication was induced by tert-butyl hydroperoxide (tBH), carbon tetrachloride ($CCl_4$), or D-glactosamine (D-GalN). Liver injury was induced by $CCl_4$, D-GalN or MCD (methionine choline deficient)-diet in mouse. The cellular leakage of lactate dehyrogenase and cell viability followed by the treatment of hepatotoxicants were significantly improved by AI-1367 treatment at a concentration range of 5~50 ${\mu}g/ml$ for tBH, 5~50 ${\mu}g/ml$ for D-GalN, and 5~100 ${\mu}g/ml$ for $CCl_4$, respectively. Treatment with AI-1367 (20, 10, 5 mg/kg, p.o.) on liver injury induced by subcutaneous injection of $CCl_4$ or D-GalN reduced significantly the levels of aspartate transaminase and alanine transaminase in serum. Histological observations revealed that fatty acid changes, hepatocyte necrosis and inflammatory cell infiltration in $CCl_4$ (D-GalN)-induced liver injury was improved by administration of AI-1367. AI-1367 treatment (10, 5, 2.5 mg/kg, p.o.) also significantly recovered the body weight change and serum levels of aspartate transaminase, alanine transaminase and triglyceride in liver injury induced by MCD diet. From these results, AI-1367 shows protective effects against tBH, $CCl_4$, D-GalN, or MCD diet-induced hepatotoxicity in vitro or in vivo.

• 한국식품영양과학회지
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• 제27권5호
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• pp.980-986
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• 1998

The effects of mungbean sprout juice on cadmium-induced hepatotoxicity in rats were investigated. Sprague-Dawley rats weighing about 90g were divided into 4 groups and raised for 6 weeks. ; control group(CON), mungbean sprouts juice-administered group(MSJ), cadmium-administered group(CAD) fed water containing 40 ppm cadmium chloride and mung bean sprouts juice and cadmium-administered group(MCD). The diet was supplied every day for the measurement of feed efficiency ratio(FER) and net weight gain was measured every 3 days. The activities of serum glutamic oxaloactic transaminase(GOT) and glutamic pyruvic transaminase(GPT), superoxide dimutase(SOD), catalase and glutathione peroxidase(GSH-Px) in the liver and the hepatic contents of glutathione were examined. The contents of Cd in liver and kidney of the rats were determined by using ICP(Inductively Coupled Plasma Emission Spectrophotometer). Growth rate and FER were decreased in CAD group, compared with CON group but the changes were not significant in MCD group. The activities of serum GOT and GPT, SOD, catalase and GSH-Px in the liver were increased by Cd administration, but the alterations were decreased by supplementation with mungbean sprouts juice. The level of glutathione decreased in CAD group(26.8$\pm$9.0mg/g liver), whereas it increased in MCD group(36.4$\pm$15.8mg gliver). The content of Cd in the liver and kidney in MCD group(9.57 ppm, 4.88 ppm) was decreased, compared with CAD group(12.81 ppm, 5.46 ppm). This result suggested that mungbean sprout juice has a lowering effect on the accumulation of Cd in the liver and kidney and it is believed that the juice has some protective effects to Cd-induced hepatotoxicity in rats, but the mechanism of these effects was obscure.

• 한국식품영양학회지
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• 제35권5호
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• pp.332-342
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• 2022

Nonalcoholic fatty liver disease (NAFLD) is recognized one of the leading metabolic diseases globally, and the younger age population with the disease is rapidly growing, especially in developed countries. Since there has been no approved medicine, losing weight is known to be the only best remedy to control or reverse the disease. Recently, the field of microbiome has attracted much attention to offer more practical choices for patients. Here, we provide experimental evidence that Streptococcus thermophilus LM1012 (LM1012), a safe probiotic strain, is effective for improving NAFLD indexes. In the methionine-choline deficient (MCD) diet induced C57BL/6 mouse model, administration of LM1012 promoted marked reductions of aspartate transaminase (23.8%), total bilirubin (27.8%), hydroxycholesterol (64.2%), triglyceride (29.7%) and IL-1β (68.3%) compared to the MCD diet alone group. Also, the histopathological data imply that LM1012 inhibited fat accumulation and inflammation in the liver, which are the key biomarkers for progression of the disease. Together, these findings suggest that human consumption of LM1012 as a healthy nutritional supplement, may be helpful in reducing the risk of liver damages in NAFLD patients.

• Journal of Medicine and Life Science
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• 제19권3호
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• pp.125-129
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• 2022

Patients with nephrotic syndrome (NS) are generally known to be at greater risk for thrombosis, with arterial thrombosis-related complications being relatively rare compared to venous thrombosis-related complications. This report describes a 46-year-old male with historically proven minimal change disease (MCD) complicated by acute aortoiliac thrombosis. He had been diagnosed with MCD 8 months previously and was treated successfully with steroids. He was prescribed a second course of high-dose steroids (prednisolone 1 mg/kg/day) due to a relapse of MCD at the outpatient clinic 8 days before the emergency department visit. The patient presented with severe pain in both lower limbs and was diagnosed with aortoiliac thrombosis that developed during high-dose steroid treatment. He subsequently underwent surgical thromboembolectomy. Hypoalbuminemia has the strongest association with the risk of thromboembolism. According to international clinical practice guidelines, anticoagulant therapy is recommended when serum albumin is ≤2-2.5 g/dL. However, as serum albumin levels may be relatively high in the early phase of NS, as in this case report, an individualized anticoagulation strategy for each patient should be considered, regardless of serum albumin levels.

• 대한원격탐사학회지
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• 제36권5_1호
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• pp.725-733
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• 2020

본 연구의 목적은 (1) MCD12Q1 자료를 이용하여 시계열 마스크 맵 작성하여 (2) 시계열 마스크 맵의 연차별 논벼 재배면적 변화를 추출하고, (3) MYD13Q1 NDVI와 단수와의 상관계수를 비교하여 (4) 적용성을 검토하는 것이다. 이를 위해 2002년부터 2019년까지의 연도별 MCD12Q1 PFT 자료를 수집하여 시계열 마스크 맵을 작성하고 고정형 마스크 맵과 비교하였다. 그 결과, 시계열 마스크 맵에 의한 논벼 재배면적이 실제 논벼 재배면적의 변동 특성을 잘 반영하고 있는 것으로 나타났으며, 고정형 마스크 맵과 비교하여 NDVI와 논벼 단수와의 상관계수도 높게 나타나 시계열 마스크 맵이 논벼 고유의 식생지수 추출 및 작황 모니터링, 단수 추정의 정확도를 높이는 방법임을 확인하였다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 1997년도 제12회 학술발표회 논문개요집
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• pp.139-139
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• 1997

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2003년도 하계학술연구발표회 및 한.일 공동심포지엄
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• pp.266-267
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• 2003

The most distinguishing character of diluted magnetic semiconductors (DMSs) is a strong interaction between sp-carriers and localized d-spins (sp-d exchange interaction). Recently many "room-temperature (RT) ferromagnetic DMS" have been reported. However, it should be noted that their sp-d exchange interactions have not been confirmed yet. The lack of a clear evidence of the sp-d exchange interaction causes the controversy on the origin of the observed ferromagnetism. For the detection of the sp-d exchange interaction, magneto-optical spectroscopy such as a magnetic circular dichroism (MCD) measurement is the most powerful tool. By using the MCD spectroscopy, we have shown the sp-d exchange interactions in Zn$_{l-x}$Cr$_{x}$Te. Recently, we have obtained the RT ferromagnetism in a Zn$_{l-x}$Cr$_{x}$Te (x = 0.20) film.0) film.

• 한국컴퓨터산업교육학회:학술대회논문집
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• 한국컴퓨터산업교육학회 2003년도 제4회 종합학술대회 논문집
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• pp.87-94
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• 2003

Anisotropic diffusion is a selective smoothing technique that promotes smoothing within a region instead of smoothing across boundaries. In anisotropic diffusion, the rate of smoothing is controlled by the local value of the diffusion coefficient chosen to be a function of the local image gradient magnitude. El-Fallah and Gary E. Ford represented the image as a surface and proved that setting the inhomogeneous diffusion coefficient equal to the inverse of the magnitude of the surface normal results in surface evolving speed that is proportional to the mean curvature of the image surface. This model has the advantage of having the mean curvature diffusion (MCD) render invariant magnitude, thereby preserving structure and locality. In this paper, the proposed MCD model efficiently reduces diffusion coefficient at the thin edges using the smoothness of the surface.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2002년도 Proceedings of International Symposium on Remote Sensing
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• pp.54-58
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• 2002

Mean curvature diffusion (MCD) is a selective smoothing technique that promotes smoothing within a region instead of smoothing across boundaries. By using mean curvature diffusion, noise is eliminated and edges are preserved. In this paper, we propose methods of automatic parameter selection and implementation for the MCD model coupled to min/max flow. The algorithm has been applied to high resolution aerial images and the results show that noise is eliminated and edges are preserved after removal of noise.