• Title/Summary/Keyword: MC50

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RESEARCH ON SPACE ENVIRONMENTAL EFFECT OF ORGANIC COMPOSITE MATERIALS FOR THERMAL MANAGEMENT OF SATELLITES USING MC-50 CYCLOTRON (MC-50 싸이클로트론을 이용한 위성용 열조절 유기복합재료의 우주환경 영향 연구)

  • Kim, Dae-Weon;Kim, Dong-Iel;Huh, Yong-Hak;Yang, Tae-Keun;Lee, Ho-Young;Kim, Yong-Hyup
    • Journal of Astronomy and Space Sciences
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    • v.22 no.4
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    • pp.441-450
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    • 2005
  • The organic material is one of the most popular material for the satellites and the spacecrafts in order to perform the thermal management, and to protect direct exposure from the space environment. The present paper observes material property changes of organic material under the space environment by using ground facilities. One of the representative organic thermal management material of satellites, 2 mil ITO(Indium Tin Oxide) coated aluminized KAPTON was selected for experiments. In order to investigate the single parametric effect of protons in space environment, MC-50 cyclotron system in KIRAMS(Korea Institute of Radiological and Medical Science) was utilized for the ion beam irradiation of protons and ion beam dose was set to the Very Large August 1972 EVENT model, the highest protons occurrence near the earth orbit in history. The energy of ion beam is fixed to 30MeV(mesa electron volt), observed average energy, and the equivalent irradiance time conditions were set to 1-year, 3-year, 5-year and 10-year exposure in space. The procedure of analyses includes the measurement of the ultimate tensile strength for the assessment of quantitative degradation in material properties, and the imaging analyses of crystalline transformation and damages on the exposed surface by FE-SEM(Field Emission Scanning Electron Spectroscopy) etc.

Shelf-life and Quality Characteristics of Tofu Coagulated by Calcium Lactate (젖산칼슘을 응고제로 한 두부의 품질특성과 저장성)

  • 이명예;김순동
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.2
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    • pp.412-419
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    • 2004
  • To investigate the utilization of calcium lactates (CaL) as coagulants for tofu manufacture, the quality characteristics and shelf-life of tofu made by CaL-P (black snail powder) and CaL-A (black snail ash) were investigated and compared to calcium chloride (CC), magnesium chloride (MC), calcium sulfate (CS ) and standard calcium lactate (CaL-S). And also, total microbe and turbidity of the tofu were determined during storage at 1$0^{\circ}C$. Coagulation ability of CaL-A was the highest, and the ability of CaL-P was higher than that of CaL-S. Yield of CaL-A tofu was similar to those of CS and CC tofu, while the yield of CaL-P tofu was 50% compared to that of CC. L* value of CaL-P tofu was lower, but a* and b* values were higher than those of other tofus. The hardness of tofu showed in the order of CaL-S>CS>CC>CaL-P>MC>CaL-A, while the cohesiveness showed in the order of MC>CaL-S>CC>CS>CaL-P>CaL-A. Calcium contents were 57 mg% in MC tofu, 174 mg% in CS tofu, 116 mg% in CaL-S tofu, 95 mg% in CaL-A tofu and 172 mg% in CaL-P tofu. From the results of microscopic observations, the lower hardness showed the more soft and the smaller particle. The particle of CaL-A tofu was small and uniformity but the size of CaL-P and CC tofu showed coarse. Sensory quality of CaL-P and -A tofu were better than the other tofu evaluated by texture, springiness, flavor and overall taste. The shelf-life estimated by total microbe was 4∼6 days in CC, MC, CS, CaL-S and CaL-A tofu, but 8 days in CaL-P tofu at 1$0^{\circ}C$. From the above results, the CaL-P and -A may believe to use as coagulant for tofu manufacture due to its softened taste and enhanced shelf-life, and higher calcium content which has higher absorbability in human body.

Spasmolytic and Anti-peptic Ulcer Activities of Crude Drugs Acting on Gastrointestinal Tract in Rats (흰쥐에서 위장관에 작용하는 생약의 진경 및 항위궤양 효능)

  • Jo, Seung-Gil;Park, Hye-Ran;Kim, Chang-Jong
    • YAKHAK HOEJI
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    • v.40 no.5
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    • pp.591-598
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    • 1996
  • The water extracts of ten crude drugs were tested for the spasmolytic and anti-peptic ulcer activities on rat ileum smooth muscle contraction and aspirin-induced acute hemorrhag ic erosive gastritis respectively. The water extract of Aurantii immaturi pericarpium(AIP)($IC_{50}=1.5{\times}1O^{-2}$g/l), Aurantii nobilis pericarpium(ANP)($IC_{50}=2.5{\times}1O^{-2}$g/l), Cyperi rhizoma(CR)($IC_{50}=3.3{\times}1O^{-2}$g/l). Linderae radix(LR) ($IC_{50}=6.8{\times}1O^{-2}$), Aurantii fructus immaturus(AFI)($IC_{50}=11.8{\times}1O^{-2}$), Saussureae radix(SR)($IC_{50}=13.2{\times}1O^{-2}$g/l) and Ponciri fructus(PF)($IC_{50}=23.3{\times}1O^{-2}$g/l) showed inhibitory activity on the isometric contraction of rat ileum smooth muscle induced by electrical stimulation in a concentration-dependent manner, whereas the water extracts of Arecae pericarpium(AP), Agastachis herba(AH) and Magnoliae cortex(MC) potentiated the isometric contraction. In the aspirin-induced acute gastritis, the water extracts of MC, AP and CR reduced significantly the gastric juice secretion, gastric juice acidity and pepsin activity. They also showed protective activity of gastric mucosal layer from erosion and petichial hemorrhage in gross and histological examination.

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A Study on Optimum Moisture Content and C/N ratio of Sewage Sludge Treatment Using Composting (퇴비화를 이용한 하수슬러지 처리에 있어서 적정 수분함량과 C/N비에 관한 연구)

  • 손현석;양원호;정문식
    • Journal of Environmental Health Sciences
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    • v.23 no.2
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    • pp.44-56
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    • 1997
  • When sewage sludge is treated by cornposting, higher moisture content and lower C/N ratio on sewage sludge is problems. This paper project to alesolve two problems. The almost trends in run 3 of MC 70% are similar to these in run 1 and 4 of MC 65%. A retention time of the highest temperature (>50$\circ$C) and increase rate of temperature in run 3 are an affinity to these in run 4. Particularly, decrease rate of temperature in run 3 is slower than others and this data shows the more activity of thermal microbial in run 3 than that in others. C/N ratio trends in run 3 shows slow reaction in initial stage but, after 9 days, is similar to that in run 1 and 4. Carbon trends in each run are a similarity to C/N ratio trends. Temperature, MC, carbon and C/N ratio trends in run 5, whose C/N ratio is 15, show less microbial activity than that in run 6, whose C/N ratio is 20. But temperature increase of the beginning stage and pH of the final stage in run 5 are greater than that in run 6. Final MC and carbon content in run 5 and 6 have a similar values. That is, final MC in run 5 and 6 is 49.39% and 48.97% and final carbon content in each run is 25.15% and 22.20%. Expecially, a temperature increase and C/N ratio decrease rate of the beginning stage in run 5 are greater than these in run 6. This shows the shorter lag time in run 5 than lag time in run 6.

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Apoptotic effect of Me fraction of Scutellaria barbata in human leukemic U937 cells (반지련의 Methyl chloride 분획이 U937 단핵 세포 암주의 세포고사에 미치는 영향)

  • Cha Yun Yi;Lee Eun Ok;Lee Ju Ryoung;Kang In Cheol;Park Young Doo;Ahn Kyoo Seok;Kim Sung Hoon
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.3
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    • pp.629-632
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    • 2003
  • Scutellaria barbata has been used as a traditional Chinese Herb for treating liver, lung and rectal tumors. In the present study, cytotoxic effect of Scutellaria barbata MC fradtion was investigated and it was found to inhibit proliferation of human leukemic U937 cells with an IC50 of approximately 10 μg/ml in a dose-dependent manner. We also demonstrated that Scutellaria barbata MC fraction caused apoptosis in U937 cells. In the flow cytometric assay, the MC fraction-treated U937 cells showed an increase in hypo-diplold Sub G1 DNA contents. DNA fragmentation was observed by TUNEL assay. An increase of Bax:Bcl-2 ratio, activation of caspase-9, caspase-3, and cleavage of poly (ADP-ribose) polymerase (PARP) were demonstrated by western blot analysis. Taken together, these results exerted that the MC fraction suppressed human leukemic U937 cell proliferation by inducing apoptosis via the mitochondrial pathway.

A Study on Solidification and Wear Character of Multi-alloyed White Cast Iron

  • Yu, Sung-Kon;Matsubara, Yasuhiro
    • Journal of Korea Foundry Society
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    • v.20 no.4
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    • pp.260-268
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    • 2000
  • 응고 및 마모거동을 연구하기 위하여 Cr, V, Mo 및 W의 조성이 다른 3종류의 백주철을 주조하였다. 고주파유도용해로에서 장입시켜 1873K까지 승온시켜 장입원료들을 모두 용해시킨 후 1823K에서 Y블럭주형에 주입하였다. 얻어진 3종류의 백주철조성은 다음과 같다: Fe-3%C-10%Cr-5%Mo-5%W(합금1), Fe-3%C-10%V-5%Mo-5%W(합금2) 및 Fe-3%C-17%Cr-3%V(합금 3)응고과정을 추적하기 위하여 각 시편으로부터 50g을 채취한 후 알루미나도가니에 넣고 실리콘카바이드로를 사용하여 1723K의 알콘분위기하에서 재용해를 시켰다. 용금을 10K/분의 속도로 냉각시키면서 열분석을 행하였으며 도중 몇 차례 소입 실험을 병행하였다.합금1의 경우 초정오스테나이트, (오스테나이트+$M_7C_3$)공정, (오스테나이트+$M_6C$)공정, 합금2의 경우 초정 MC, 초정오스테나이트, (오스테나이트+MC)공정 , (오스테나이트+$M_2C$)공정, 합금3의 경우 초정 $M7C_3$와 (오스테나이트+$M_7C_3$)공정으로 구성되어 있었다. 주방상태, 균질화열처러상태, 공냉상태, 템퍼링상태에서 내마모시험을 행하였다. 먼저 주방상태시 편을 진공분위기하에서 1223K에서 5시간동안 균질화열처리를 행한후 로냉을 시켰다. 다시 이 시편을 1323K에서 2시간 유지후 강제공냉을 시켰으며 강제공냉된 시편을 573K에서 3시간동안 템퍼링처리를 하였다. 내마모시험은 120 mesh마모지에 10N의 하중을 가하여 실시하였다. 각 사이클마다 무게감소를 측정하였으며 8번 반복실험을 하였다. 마모량은 균질화열처리시편, 주방상태시편, 템퍼링시편, 공냉시편의 순으로 감소하였다. 합금2가 마모량이 가장 적었으며 합금3이 가장 많았다. 합금2의 마모량이 가장 적은 이유는 조직이 초정 MC, 공정 MC 및 공정 M2C로 구성되어 있기 때문으로 사료된다.주방상태에서 기지조직은 퍼얼라이트이었으나 열처리를 통하여 마르텐사이트, 템퍼드마르텐사이트, 잔류오스테나이트로 변태하였다. 이상의 결과를 종합해 보면 MC가 내마모성에 가장 기여하는 조직으로 판단되어진다.

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The Solidification Microstructure of X%C-5%Cr-5%V-5%Mo-5%W-5%Co Multi-Component White Cast Iron (X%C-5%Cr-5%V -5%Mo-5%W-5%Co 다합금계백주철의 응고조직에 관한 연구)

  • Yu, Sung-Kon;Yasuhiro Matsubara
    • Korean Journal of Materials Research
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    • v.11 no.6
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    • pp.472-476
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    • 2001
  • Type and three-dimensional morphology of carbides precipitated in the X(X= 1.70, 1.92, 2.21, 2.50, 2.86)%C-5%Cr-5%V-5%Mo-5%W-5%Co multi-component white cast iron were investigated using an optical microscope and SEM. The types of carbides precipitated were MC, M$_2$C and M$_{7}$C$_{3}$. Morphology of the MC carbide took three forms, that it petal-like, nodular and coral-like. MC carbide seemed to change its morphology from petal-like through nodular, and finally to coral-like with an increase in carbon content. M7C carbide was classified into lamellar and plate-like type. The lamellar M$_2$C arbide precipitated in the iron with low molybdenum and tungsten contents, and higher contents of both elements in the iron were needed to form the plate-like M$_2$C carbide. The morphology of M$_{7}$C$_{3}$ was rod-like similar to that observed in high chromium white cast iron. However, cobalt does not affect the type and morphology of precipitated carbides.des.

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As-Cast and Solidification Structures of Fe-3%C-x%Cr-y%V-w%Mo-z%W Multi- Component White Cast Irons (Fe-3%C-x%Cr-y%V-w%Mo-z%W 다합금계백주철의 주방상태 및 급냉조직)

  • Yu, sung-Kon;Shin, Sang-Woo
    • Korean Journal of Materials Research
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    • v.12 no.5
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    • pp.414-422
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    • 2002
  • Three different multi-component white cast irons alloyed with Cr, V, Mo and W were prepared in order to study their as-cast and solidification structures. Three combinations of the alloying elements were selected so as to obtain the different types of carbides and matrix structures : 3%C-10%Cr-5%Mo-5%W(alloy No.1), 3%C-10%V-5% Mo-5%W(alloy No. 2) and 3%C-17%Cr-3% V(alloy No.3). The as-cast microstructures were investigated with optical and scanning electron microscopes. There existed two different types of carbides, $M_7C_3$ carbide with rod-like morphology and $M_6C$ carbide with fishbone-like one, and matrix in the alloy No. 1. The alloy No. 2 consisted of MC carbide with chunky and flaky type and needle-like $M_2C$ carbide, and matrix. The chunky type referred to primary MC carbide and the flaky one to eutectic MC carbide. The morphology of the alloy No. 3 represented a typical hypo-eutectic high chromium white cast iron composed of rod-like $M_7C_3$ carbide which is very sensitive to heat flow direction and matrix. To clarify the solidification sequence, each iron(50g) was remelted at 1723K in an alumina crucible using a silicon carbide resistance furnace under argon atmosphere. The molten iron was cooled at the rate of 10K/min and quenched into water at several temperatures during thermal analysis. The solidification structures of the specimen were found to consist of austenite dendrite(${\gamma}$), $ ({\gamma}+ M_7C_3)$ eutectic and $({\gamma}+ M_6C)$ eutectic in the alloy No. 1, proeutectic MC, austenite dendrite(${\gamma}$), (${\gamma}$+MC) eutectic and $({\gamma}+ M_2C)$ eutectic in the alloy No. 2, and proeutectic $M_7C_3$ and $ ({\gamma}+ M_7C_3)$ eutectic in the alloy No 3. respectively.

Immune-Enhancing Effects of Phellinus linteus Fruit Body and Mycelium Cultured in Cudrania tricuspidata (꾸지뽕나무 배양 상황버섯 자실체 및 균사체의 면역증진 효과)

  • Hong, Da Hyun;Joo, In Hwan;Park, Jong Min;Han, Su Hyun;Lee, Su Bin;Gwak, Seong Geun;Kim, Dong Hee
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.33 no.5
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    • pp.275-281
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    • 2019
  • Polysaccharides produced in microorganisms and plants are known to increase the immune response in the body. We proposed analysis of beta-glucan contents of phellinus linteus fruit body (FB) and mycelium (MC) cultured in cudrania tricuspidata. Also, we examined whether fruit body and mycelium can increase the immune response in cyclophosphamide-induced immunosuppression animal models. We injected cyclophosphamide (50 mg/kg) twice to produce immunosuppression mice. Then, FB (200 mg/kg) and MC (200 mg/kg) were oral administered for 14 days. In order to confirm the immune-enhancing effect of FB and MC, we analyzed spleen weight, the number of immune cells, cytokines, and immunoglobulins levels. Cyclophosphamide decreased the weight of spleen, the number of immune cells. However, FB and MC have significantly increased the weight of spleen, the number of white blood cell, lymphocyte and monocyte. In addition, they have significantly increased immune-related cytokines (IL-2 and IFN-${\gamma}$) and immunoglobulins (IgA, IgG, IgM) levels. As a results, phellinus linteus fruit body (FB) and mycelium (MC) cultured in cudrania tricuspidata can be used as effective natural materials for immune-enhancing.

Effects of ADCYP1R1, FABP3, FABP4, MC4R, MYL2 Genotypes on Growth Traits in F2 Population Between Landrace and Jeju Native Black Pig (제주재래흑돼지와 Landrace의 F2 집단에서 ADCYP1R1, FABP3, MC4R, MYL2 유전자형이 성장형질에 미치는 효과)

  • Han, Sang-Hyun;Shin, Kwang-Yun;Lee, Sung-Soo;Ko, Moon-Suck;Jeong, Dong-Kee;Jeon, Jin-Tae;Cho, In-Cheol
    • Journal of Animal Science and Technology
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    • v.50 no.5
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    • pp.621-632
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    • 2008
  • Genetic polymorphisms was investigated at five single nucleotide polymorphisms(SNP) sites in four porcine genes(ADCYAP1R1, FABP3, MC4R, and MYL2) and analyzed their statistical association with growth traits in F2 reciprocal-crossbred population between Landrace and Jeju native black pig(JNP). All populations, JNP, Landrace and their F2 were polymorphic for all five SNP loci tested, however, the homozygote T/T of FABP3 g.-158T>C and the homozygote G/G of ADCYAP1R1 intron 2 337A>G were not found in JNP and Landrace, respectively. The genotypes of ADCYAP1R1 were significantly associated with body weights(BW) at 3 weeks and at 20 weeks(P<0.05), respectivley, those of FABP3 g.-135delT were associated with late average daily gain(LADG) (P<0.01), and those of FABP3 g.-158T>G were associated with body weights during late growth period such as, BW20 and LADG(P<0.01). Those of MC4R were also significantly associated with BW10 suggesting by the difference of early average daily gain(EADG) (P<0.05), and with LADG(P<0.01). The body length of F2 animals was affected by the genotypes of ADCYAP1R1, MC4R, and MYL2(P<0.05), respectively. Among these, MC4R A/A homozygotes showed over 3 cm longer in body length than those of other genotypes. As the useful basic information, these results suggested that SNP markers showing statistical association with growth traits and the results help to select the sires of JNP for improving the productivity in JNP-related crossbreeding system in pig industry and also to construct the molecular breeding system for breed improvement of JNP itself.