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http://dx.doi.org/10.5187/JAST.2008.50.5.621

Effects of ADCYP1R1, FABP3, FABP4, MC4R, MYL2 Genotypes on Growth Traits in F2 Population Between Landrace and Jeju Native Black Pig  

Han, Sang-Hyun (National Institute of Animal Science, RDA)
Shin, Kwang-Yun (National Institute of Animal Science, RDA)
Lee, Sung-Soo (National Institute of Animal Science, RDA)
Ko, Moon-Suck (National Institute of Animal Science, RDA)
Jeong, Dong-Kee (Department of Animal Biotechnology, Cheju National University)
Jeon, Jin-Tae (Division of Applied Life Science, Gyeongsang National University)
Cho, In-Cheol (National Institute of Animal Science, RDA,)
Publication Information
Journal of Animal Science and Technology / v.50, no.5, 2008 , pp. 621-632 More about this Journal
Abstract
Genetic polymorphisms was investigated at five single nucleotide polymorphisms(SNP) sites in four porcine genes(ADCYAP1R1, FABP3, MC4R, and MYL2) and analyzed their statistical association with growth traits in F2 reciprocal-crossbred population between Landrace and Jeju native black pig(JNP). All populations, JNP, Landrace and their F2 were polymorphic for all five SNP loci tested, however, the homozygote T/T of FABP3 g.-158T>C and the homozygote G/G of ADCYAP1R1 intron 2 337A>G were not found in JNP and Landrace, respectively. The genotypes of ADCYAP1R1 were significantly associated with body weights(BW) at 3 weeks and at 20 weeks(P<0.05), respectivley, those of FABP3 g.-135delT were associated with late average daily gain(LADG) (P<0.01), and those of FABP3 g.-158T>G were associated with body weights during late growth period such as, BW20 and LADG(P<0.01). Those of MC4R were also significantly associated with BW10 suggesting by the difference of early average daily gain(EADG) (P<0.05), and with LADG(P<0.01). The body length of F2 animals was affected by the genotypes of ADCYAP1R1, MC4R, and MYL2(P<0.05), respectively. Among these, MC4R A/A homozygotes showed over 3 cm longer in body length than those of other genotypes. As the useful basic information, these results suggested that SNP markers showing statistical association with growth traits and the results help to select the sires of JNP for improving the productivity in JNP-related crossbreeding system in pig industry and also to construct the molecular breeding system for breed improvement of JNP itself.
Keywords
Jeju native black pig; Landrace; Growth traits; SNP; Association
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Times Cited By KSCI : 15  (Citation Analysis)
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