• Journal of Periodontal and Implant Science
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• v.42 no.1
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• pp.3-12
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• 2012

Purpose: Anti-rheumatic agents target common molecular pathways of inflammation in rheumatoid arthritis (RA) and periodontitis. The purpose of this study was to determine the relative effect of anti-rheumatic agents on the levels of inflammatory biomarkers and periodontal inflammation in RA patients with periodontitis. Methods: A systematic review and meta-analysis were conducted of studies comparing periodontal parameters of inflammation, such as bleeding on probing, and biomarkers of inflammation in RA patients with periodontitis and healthy adults with and without periodontitis. The search included the electronic databases MEDLINE, Cochrane Database of Systematic Reviews, and Google Scholar, inclusive through October 2011, with no language restrictions. Hand searches were conducted of the bibliographies of related journals and systematic reviews. Observational and interventional studies assessing the effects of antirheumatic therapy qualified for inclusion. Two reviewers performed independent data extraction and risk-of-bias assessment. Of the 187 identified publications, 13 studies fulfilled the inclusion criteria. Results: When compared to healthy adults without periodontitis, RA subjects were found to have significantly higher levels of bleeding on probing and limited evidence of higher levels of interleukin-$1{\beta}$ and tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) in gingival crevicular fluid and saliva. No consistent differences were found in periodontal parameters and inflammatory biomarkers between RA subjects and adults with periodontitis. Studies evaluating the effect of anti-TNF-${\alpha}$ therapy in RA subjects with periodontitis have yielded inconsistent results. Conclusions: There are limited data, however, to suggest that anti-TNF-${\alpha}$ agents can reduce local production of inflammatory cytokines and periodontal inflammation in RA patients with periodontitis.

• Fisheries and Aquatic Sciences
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• v.16 no.1
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• pp.35-39
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• 2013

The aim of this study was to assess visible implant fluorescent elastomer (VIE) tagging in greenling Hexagrammos otakii. The experiental fish were anesthetized individually and marked with orange, yellow, red, and green elastomer at the following five body locations, respectively: the adipose eyelid, the surface of the dorsal fin base, the inside surface of the pectoral fin base, the inside surface of the pelvic fin base, and the surface of the anal fin base. Control fish were anesthetized but not marked. During the 20-month trial, fish growth and retention, underwater visibility, and readability of the tags were determined. After 20 months, body length of marked greenling ($43.2{\pm}3.5cm$, mean ${\pm}$ standard deviation [SD]) did not differ from that of the control ($41.4{\pm}3.7cm$). Additionally, the body weight of marked greenling ($527.4{\pm}39.8g$, mean ${\pm}$ SD) did not differ from that of the controls ($505.9{\pm}31.7g$). Greenling retained >90% of the tags at the surface of the dorsal fin base. The anal fin base showed a higher tag retention rate than the inside surfaces of the pectoral fin and the pelvic fin bases (P < 0.05). Red and orange tags were identified more easily underwater than green and yellow tags. Green and yellow tags emitted fluorescence in response to a narrower range of light wavelengths. Thus, the VIE mark was easy to apply to greenling (< 1 min per fish) and was readily visible when viewed under an ultraviolet lamp.

• The Journal of the Korea Contents Association
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• v.10 no.3
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• pp.64-71
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• 2010

Recently, to achieve high performance of the processor, the cache is splits physically into two parts, one for instruction and one for data. This paper proposes an architecture of asynchronous instruction cache based on mixed-delay model that are DI(delay-insensitive) model for cache hit and Bundled delay model for cache miss. We synthesized the instruction cache at gate-level and constructed a test platform with 32-bit embedded processor EISC to evaluate performance. The cache communicates with the main memory and CPU using 4-phase hand-shake protocol. It has a 8-KB, 4-way set associative memory that employs Pseudo-LRU replacement algorithm. As the results, the designed cache shows 99% cache hit ratio and reduced latency to 68% tested on the platform with MI bench mark programs.

• Journal of Plant Biotechnology
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• v.43 no.3
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• pp.302-310
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• 2016

A study aimed at identifying putative drought responsive genes that confer tolerance to water stress deficit in tea plants was conducted in a 'rain-out shelter' using potted plants. Eighteen months old drought tolerant and susceptible tea cultivars were each separately exposed to water stress or control conditions of 18 or 34% soil moisture content, respectively, for three months. After the treatment period, leaves were harvested from each treatment for isolation of RNA and cDNA synthesis. The cDNA libraries were sequenced on Roche 454 high-throughput pyrosequencing platform to produce 232,853 reads. After quality control, the reads were assembled into 460 long transcripts (contigs). The annotated contigs showed similarity with proteins in the Arabidopsis thaliana proteome. Heat shock proteins (HSP70), superoxide dismutase (SOD), catalase (cat), peroxidase (PoX), calmodulinelike protein (Cam7) and galactinol synthase (Gols4) droughtrelated genes were shown to be regulated differently in tea plants exposed to water stress. HSP70 and SOD were highly expressed in the drought tolerant cultivar relative to the susceptible cultivar under drought conditions. The genes and pathways identified suggest efficient regulation leading to active adaptation as a basal defense response against water stress deficit by tea. The knowledge generated can be further utilized to better understand molecular mechanisms underlying stress tolerance in tea.

• Journal of the Korea Furniture Society
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• v.22 no.3
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• pp.160-173
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• 2011

Increased internet use under a ubiquitous environment may be called as a great human information space revolution followed by Industrial Revolution. This revolution is exerting its significant influence over all the industry as a whole with speed faster than that of any other times. Along with this trend, if furniture design field that leads living culture should fail to jump on this main stream without noticing it, it may be reduced to a unpopular field some day without any sign of recovery. Under this background, this study is intended to recognize a goal aiming at understanding our rapidly changing living environment and leading our way positively. Currently, our surrounding living environment is immersed in computers here and there and Mark Weiser once defined a system that moves in advance before an action as ubiquitous computing and in this respect, I am going to observe a detailed transformation process of space. First nature of the space may be defined as atoms, a physical space equivalent to a spatial element and Bits space that is untouchable is usually called as 2nd space and a combination of atoms and Bits is an intelligent space - 3rd space - that can be intelligible without touching it and finally, this space is called as a ubiquitous space. This spatial transformation is developed by several changes of living environment and we may call it as living trend or interior design trend. Transformation in terms of social perspective, space structural perspective and digital technique perspective may be enumerated. These transformations were surveyed based on its contents being implemented at a future housing exhibition hosted by 5 construction companies along with fusion of information furniture and furniture depending on each housing space. In conclusion, it could be realized that most of the companies were decorating future space by implementing ubiquitous environment as a success factor of future housing market. It may be meaningful to note once again that under an interior environment, a fusion of furniture and information furniture is required considering interior trend elements.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.51 no.2
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• pp.227-234
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• 2015

To obtain geographical range and growth-kinetics parameters of mottled sake (Beringraja pulchra) populations in the Yellow Sea, three mark-recapture experiments were carried out. Overall, 991 tagged individuals were released, and 4.1% of them were recaptured with the mean release period of 339 d (range, 8-1,420 d) and the mean growth rate of $1.4cm\;mon^{-1}$ (female, $1.5cm\;mon^{-1}$; male $1.3cm\;mon^{-1}$). In the first experiment, 667 individuals were released at Heuksan Island from April to June, 2007-2009, and 30 individuals were recaptured mainly at the north and the north-east coasts of the island, indicating absence of migration to the south of the island. In the second experiment, 323 individuals were released at several fishing grounds scattered in the Yellow Sea in 2010-2013, and 11 individuals were recaptured at points deviated to all directions from the releasing points. As the last, one individual was released with pop-up satellite archival tag at a costal point ($34^{\circ}37.2$'N, $124^{\circ}59.3$'E) off Hong Island on May 21, 2010. The tagged individual migrated to a north-east location ($35^{\circ}50.4$'N, $126^{\circ}03.6$'E) of Eocheong Island by Aug. 25, 2010. The data archived for the three months in the tag indicated that the migration path had depths of 48-80 m and temperature of $12.6-14.4^{\circ}C$. The results indicated that mottled sake populations had a localized habitat ranges at the north of Heuksan Island and the west of Hong Island while growing at the rate of $1.4cm\;mon^{-1}$.

• The KSFM Journal of Fluid Machinery
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• v.18 no.3
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• pp.46-52
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• 2015

Pump-turbine system is widely used by the hydropower industry for stabilizing the electrical grid in the vast growing economy of most developed countries. This study only investigates the Fluid-structure Interaction (FSI) analysis of the pump-turbine system at various operating conditions. The FSI analysis can show how reliable each component of the system is by providing the engineer with a better understanding of high stress and deformation points, which could reduce the lifespan of the pump-turbine. Pump-turbine components are categorized in two parts, pressurized static parts and movable stressed parts. The fixed parts include the spiral casing, top and bottom cover, stay vane and draft tube. The movable parts include guide vanes and impeller blades. Fine hexahedral numerical grids were used for CFD calculation and fine tetrahedral grids were used for structural analysis with imported load solution mapping greater than 90 %. The maximum equivalent stress are much smaller than the material yield stress, and the maximum equivalent stress showed an increasing tendency with the varying of operating conditions from partial to excessive at both modes. In addition, the total deformation of all the operating conditions showed a small magnitude, which have quite small influence on the structural stability. It can be conjectured that this system can be safely implemented.

• Journal of Power Electronics
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• v.16 no.6
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• pp.2035-2044
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• 2016

In order to match the voltages between high voltage battery stacks and low voltage super-capacitors with a high conversion efficiency in hybrid energy sources electric vehicles (HESEVs), a high ratio bidirectional DC-DC converter with a synchronous rectification H-Bridge is proposed in this paper. The principles of high ratio step-down and step-up operations are analyzed. In terms of the bidirectional characteristic of the H-Bridge, the bidirectional synchronous rectification (SR) operation is presented without any extra hardware. Then the SR power switches can achieve zero voltage switching (ZVS) turn-on and turn-off during dead time, and the power conversion efficiency is improved compared to that of the diode rectification (DR) operation, as well as the utilization of power switches. Experimental results show that the proposed converter can operate bidirectionally in the wide ratio range of 3~10, when the low voltage continuously varies between 15V and 50V. The maximum efficiencies are 94.1% in the Buck mode, and 93.6% in the Boost mode. In addition, the corresponding largest efficiency variations between SR and DR operations are 4.8% and 3.4%. This converter is suitable for use as a power interface between the battery stacks and super-capacitors in HESEVs.

• Journal of the Korean association of regional geographers
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• v.11 no.6
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• pp.517-529
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• 2005

Mt. Apsan is well known to be one of the most popular tourist sites around Daegu. Annually, more than 16 million persons visit Mt. Apsan. Although, in the mountain there are varieties of geomorphic and geological resources, there has been less concern to utilize the resources for geo-tourism. For example, there are about 10 valleys within Mt. Apsan and various landforms are scattered around the valleys. In this context, this study, based on field surveys centering around Gosangol valley, Anjiranggol valley and Dalbigol valley, focuses on exploring ways towards developing Mt. Apsan as an example geo-tourist site. The main findings are as follows: 1) The main landforms of Mt. Apsan include river cliff, cavern, free face, mud crack, ripple mark, fold, sheeting joint, talus, alluvial fan, pot hole, fault line, gnamma, columnar joint and metamorphic rock. 2) The guide notes on the landforms are developed. 3) In order to raise a learning effect of visitors on geomorphic resources, 9 nature trails are designed according to valleys and the length of visitor's stay.

• Journal of Digital Convergence
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• v.18 no.3
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• pp.357-362
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• 2020

By analyzing abstract book cover design, this study aims to examine the applicability of the semiotic methodology of Roland Barthes and to conduct a preference survey of how people would accept it. The selected books for the study are and published in Openbooks publishing company to mark the 30^th anniversary of the opening. The research results are as follows. First, it was confirmed that Roland Barthes' semiotic approach is a suitable tool for identifying the symbolic phenomena of visual elements that constitute abstract book cover design. Second, people were well informed of what the abstract form of design conveys, but they showed personal differences in preference, making it difficult to achieve clear results. This study, together with the importance of the internal meaning that appears in the book cover design, gives graphic designers an indication that interaction between the communicator and the acceptor should be sought.