• Title/Summary/Keyword: M11

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Effect of the Ethanol Extract from Citrus Peels on Oxidative Damage in Alloxan-induced HIT-T15 Cell (진피 에탄올 추출물이 Alloxan에 의해 유도된 HIT-T15 세포의 산화적 손상에 미치는 영향)

  • Jung, Hee-Kyoung;Jeong, Yoo-Seok;Park, Chi-Deok;Park, Chang-Ho;Hong, Joo-Heon
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.8
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    • pp.1102-1106
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    • 2010
  • This study was carried out to investigate the effect of ethanol extract from citrus peels (CP-Et) against the alloxan-induced oxidative damage on HIT-T15, Hamster pancreatic $\beta$-cell. Total polyphenol and flavonoid contents in CP-Et were $57.00{\pm}2.91\;mg/g$ and $8.11{\pm}2.83\;mg/g$, respectively. Cell toxicity on HIT-T15 by CP-Et (0.125~0.75 mg/mL) was not observed. CP-Et (0.125 mg/mL) increased cell proliferation rate of HIT-T15, which was treated alloxan ($IC_{50}=11.58\;mM$) (cell viability=$80.52{\pm}3.29%$ of normal cell, p<0.05). In comparison with insulin secretion of oxidative damaged HIT-T15, 1.5 fold ($116.93{\pm}2.11\;{\mu}g/mg$ protein) was increased by treatment CP-Et treatment (0.125 mg/mL) in HIT-T15 (p<0.05). These results showed that CP-Et contribute to repairing cells and improvement of insulin expression on oxidative stress pancreatic $\beta$-cell, and also suggested application of CP-Et as a functional food material for type 2 diabetes.

Bacillus licheniformis SSA3-2M1 이 생산하는 Proteinases

  • 장영채;이경형;김성영;조윤래;김종규
    • Korean Journal of Microbiology
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    • v.30 no.4
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    • pp.239-245
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    • 1992
  • Buci1llr.s 11c~h~n~1rnSiSi.As 3-2MI which is responsible for the special taste of traditionalKorean soy sause produced two kinds of proteinase. The activity of the proteinasc I washigher about two fold than that of proteinase 11. The optimai, reaction pH of proteinaseI and I1 wcre found to be 7-1 1.5 and 7-9. respectively. Proteinase I1 was more stable andactive than proteinase I at pH ranges around 3 to 5. The optimal te~tlperature of proteinaseI and I1 were 502. The temperature stabilitl of proteinase I1 was Inore stable thanproteinase 1 at temperature range around 30-quot;~A. ctivities of proteinase I and I1 graduallydeclined above $30^{\circ}$C and 45C. respectively. Proteinasc 1 was more active than proteinaseI1 at salt concentration range around 25-3500. The K,,, values of casein and soy proteinfor proteinase I were 6.89 mglml and 3.98 mglml. In case of proteinase 11. they were 9.00mgiml anti 11.44 111g/ml. respectively. The activity of the crudc enzyme was increased by1 rnM Pb(CH3COO). but was decreased by 5 n1M and 10 rnM of HgS04 and ZnS04. Thetwo proteinases produced amino acids and peptides from the soybean protein. The peptideswere digested into amino acids. Both protcinases were found to be the main enzymes thatproduced amino acids which make the main taste of traditional Korean soy sauce.al Korean soy sauce.

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Preparation of Functional Seasoning Sauce Using Enzymatic Hydrolysates from Skipjack Tuna Cooking Drip (참치 자숙액 가수분해물을 이용한 건강 기능성 조미 소스의 제조)

  • Oh, Hyeun-Seok;Kim, Jin-Soo;Heu, Min-Soo
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.36 no.6
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    • pp.766-772
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    • 2007
  • The enzymatic hydrolysate of skipjack tuna cooking drip with good functionality was prepared by incubation with Alcalase for 30 min. For the preparation of functional seasoning sauce with enzymatic hydrolysate (SSE), the additives, such as concentrated enzymatic hydrolysate (100 mL), yeast extract powder (0.7 g), lactose (0.4 mL), liquid smoke (0.3 g) and sea tangle powder (1.4 g), were added to the enzymatic hydrolysate and boiled before filtration. The proximate composition of SSE was 11.8% for crude protein, 5.77 for pH and 11.9% for salinity. The SSE was higher in the crude protein, while lower in the salinity than commercial seasoning sauce. ACE inhibitory activity ($IC_{50}$) and antioxidative activity (PF) of SSE were 6.2 mg/mL and 1.14, respectively, which were superior to those (9.9 mg/mL in IC50 and 0.91 in PF) of commercial seasoning sauce. The free amino acid content (1,905.2 mg/100 mL) and taste value (58.65) of SSE were higher than in those (712.7 mg/100 mL and 34.30, respectively) of commercial sauce. Total amino acid content of SSE (10,965 mg/100 mL) was higher than that (4,818 mg/100 mL) of commercial sauce. The major amino acids of SSE were glutamic acid (12.2%), proline (11.0%), histidine (10.7%) and glycine (9.9%). The results suggested that SSE could be commercially sold.

On Fuzzy r-Minimal Semicompactness on Fuzzy r-Minimal Spaces

  • Min, Won-Keun
    • International Journal of Fuzzy Logic and Intelligent Systems
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    • v.11 no.2
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    • pp.103-107
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    • 2011
  • The concepts of fuzzy r-minimal semicompact, almost fuzzy r-minimal semicompact, and nearly fuzzy r-minimal semicompact on fuzzy r-minimal spaces arc introduced. We also investigate the relationships between fuzzy r-M-semicontinuous mappings and several types of fuzzy r-minimal semicompactness.

Studies on 5'-Phosphodiesterase produced by microoganisms - Part. I. On the 5'-Phosphodiesterase of Penicillium sclerotiorum - (미생물(微生物)에 의(依)한 5'-Phosphodiesterase생산(生産)에 관(關)한 연구(硏究) - 제1보(第一報) penicllium sclerotiornm의 5'-Phosphodiesterase에 대(對)하여 -)

  • Kim, Ho-Sik;Lee, Ke-Ho
    • Applied Biological Chemistry
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    • v.4
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    • pp.11-16
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    • 1963
  • (1) The 30 strains of Penicillia and the 52 strains of Aspergilli have been screened for their producibility of 5'-Phosphodiesterase, and Penicillium sclerotiorum 7321, Penicillium sp M-11 and Penicillium citrinum UV-mutant 2032-72 were selected as having high 5‘-Phosphodiesterase activity. (2) Using the wheat bran medium the 5‘-Phosphodiesterase production was reached at maximum state by the plate culture for 10 days at $30^{\circ}C$ (3) The optimum conditions of the 5'-Phosphodiesterase activity of Penicillium sclerotiorum 7321 and Penicillium sp M-11 were pH 4.0 at $62.5^{\circ}C$, while the optimum condition of the 5'-Phosphodiesterase activity of Penicillium citrinum UV-mutant 2032-72 was pH 5.0 at $50^{\circ}C$.

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Labor-saving Feasibilities in Transplanting of Paddy Rice I. Variations in Labor Requirements under the Various Planting Densities (수도 이앙노동의 생력화 연구 I. 이앙밀도 차이에 따른 이앙작업의 노동요구도 변동특성)

  • 구자옥;이영만;이관섭
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.30 no.1
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    • pp.20-25
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    • 1985
  • Studying of labor-saving feasibilities in transplanting work of paddy seedling, firstly the five transplanting densities were comparatively examined. The labor-savings were reached as 10, 20, 28% of the whole paddy works, and 28, 39, 61% of the transplanting works by reducing the density as 15, 11 and 8 hills per sq. meter, respectively. However the study on the crop yield and labor-productivity variations as affected by transplanting density of paddy rice was interpreted as the marginal feasibility of density reduction for labor-saving would be more or less than 11-12 hills per sq. meter.

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DC Accelerated Aging Characteristics of $Pr_{8}O_{11}$-Based ZnO Varistors with CoO Content (CoO 첨가량에 따른 $Pr_{8}O_{11}$계 ZnO 바리스터의 DC 가속열화특성)

  • 김향숙;정영철;남춘우
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2001.11a
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    • pp.467-471
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    • 2001
  • DC accelerated aging characteristics of Pr$_{6}$O$_{11}$-based ZnO varistors, which are composed of ZnO+Pr$_{6}$O$_{11}$+CoO+Cr$_2$O$_3$+Dy$_2$O$_3$ ceramics were investigated with CoO content in the range of 0.5~5.0 mol%. The varistors doped with 1.0 mol% revealing maximum value(66.61) in the nonlinear exponent exhibited excellent stability, in which the variation rates of the varistor voltage, the nonlinear exponent and leakage current are -1.93%, -10.48%, and 288.79%, respectively, under DC accelerated aging stress, such as (0.85 V$_{1mA}$/115$^{\circ}C$/24h)+(0.90 V$_{1mA}$/12$0^{\circ}C$/24h)+(0.95 V$_{1mA}$/1$25^{\circ}C$/24h)+(0.95 V$_{1mA}$/15$0^{\circ}C$/24h). Next the varistors doped with 2.0 mol% exhibiting the nonlinear exponent of 47.39 showed high stability,ity,ability,ity,

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Study of Retention of Mono-Substituted Phenols in Reversed-Phase Liquid Chromatography Based on the Linear Solvation Energy Relationships Using the Solvatochromic Parameters for Mobile Phases, ${\pi}_m^{\ast}, {\alpha}_m$ and ${\beta}_m$

  • Park, Jung-Hag;Jang, Myung-Duk;Kim, Sang-Tae
    • Bulletin of the Korean Chemical Society
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    • v.11 no.4
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    • pp.297-302
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    • 1990
  • Retention of mono-substituted phenols in reversed-phase liquid chromatography has been studied based on the linear solvation energy relationships using the solvatochromic mobile phase parameters, ${\pi}_m^{\ast}, {\alpha}_m$ and ${\beta}_m$. It has been observed that retention behavior of phenols in RPLC were well represented by regression equations vs. solvatochromic mobile phase parameters even though the equations may be incomplete due to lack of an explicit cavity term. Dependence of retention of monosubstituted phenols on the mobile phase properties were varied depending on the type of the organic cosolvent in the mobile phase, e.g., ${\beta}_m$ and {\alpha}_m$ in methanol-water system, but ${\pi}_m^{\ast} and ${\beta}_m$ in THF-water system. It has been suggested that retention of phenols in methanol-water system is controlled by the solvophobicity of the mobile phase.

Imaging dose evaluations on Image Guided Radiation Therapy (영상유도방사선치료시 확인 영상의 흡수선량평가)

  • Hwang, Sun Boong;Kim, Ki Hwan;kim, il Hwan;Kim, Woong;Im, Hyeong Seo;Han, Su Chul;Kang, Jin Mook;Kim, Jinho
    • The Journal of Korean Society for Radiation Therapy
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    • v.27 no.1
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    • pp.1-11
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    • 2015
  • Purpose : Evaluating absorbed dose related to 2D and 3D imaging confirmation devices Materials and Methods : According to the radiographic projection conditions, absorbed doses are measured that 3 glass dosimeters attached to the centers of 0', 90', 180' and 270' in the head, thorax and abdomen each with Rando phantom are used in field size $26.6{\times}20$, $15{\times}15$. In the same way, absorbed doses are measured for width 16cm and 10cm of CBCT each. OBI(version 1.5) system and calibrated glass dosimeters are used for the measurement. Results : AP projection for 2D imaging check, In $0^{\circ}$ degree absorbed doses measured in the head were $1.44{\pm}0.26mGy$ with the field size $26.6{\times}20$, $1.17{\pm}0.02mGy$ with the field size $15{\times}15$. With the same method, absorbed doses in the thorax were $3.08{\pm}0.86mGy$ to $0.57{\pm}0.02mGy$ by reducing field size. In the abdomen, absorbed dose were reduced $8.19{\pm}0.54mGy$ to $4.19{\pm}0.09mGy$. Finally according to the field size, absorbed doses has decreased by average 5~12%. With Lateral projection, absorbed doses showed average 5~8% decrease. CBCT for 3D imaging check, CBDI in the head were $4.39{\pm}0.11mGy$ to $3.99{\pm}0.13mGy$ by reducing the width 16cm to 10cm. In the same way in thorax the absorbed dose were reduced $34.88{\pm}0.93(10.48{\pm}0.09)mGy$ to $31.01{\pm}0.3(9.30{\pm}0.09)mGy$ and $35.99{\pm}1.86mGy$ to $32.27{\pm}1.35mGy$ in the abdomen. With variation of width 16cm and 10cm, they showed 8~11% decrease. Conclusion : By means of reducing 2D field size, absorbed dose were decreased average 5~12% in 3D width size 8~11%. So that it is necessary for radiation therapists to recognize systematical management for absorbed dose for Imaging confirmation. and also for frequent CBCT, it is considered whether or not prescribed dose for RT refer to imaging dose.

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