• Journal of Korean Society of Environmental Engineers
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• v.27 no.2
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• pp.158-162
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• 2005

The objective of this study was to assess the assimilable organic carbon (AOC) in processing water, a measurement of biostability, at several stages of a full-scale nanofiltration (NF) water treatment plant. The NF membrane plant investigated was a $45,400\;m^3$/day (12 mgd) water softening facility at Plantation City in southern Florida, which utilized an organic rich groundwater (dissolved organic carbon (DOC) = 17.6 mg/L) originated from a surficial aquifer. The average AOC concentration of raw feed water was estimated at 158 g/L acetate-C. After pretreatment(acid and antiscalant addition), AOC levels increased by 12.7%, suggesting that pretreatment chemicals used to control scaling may deteriorate feed water biostability. The results also demonstrated that nanofiltration was capable of effectively removing 63.4% of AOC and 94.8% of DOC from the raw water. AOC rejection in stage 1 (${\approx}\;68%$) was slightly higher than that of stage 2 (${\approx}\;58%$) indicating that AOC was removed less at the solution environment (i.e. low pH, high ionic strength and high hardness), which was often created in the $2^{nd}$ stage of full-scale membrane plants due to pretreatment (acid addition) and high recovery operation.

• Journal of Life Science
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• v.16 no.7 s.80
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• pp.1133-1140
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• 2006

Human HtrA1 (High temperature requirement protein A1) is a homologue of the E. coli periplasmic serine protease HtrA. A recent study has demonstrated that HtrA1 is a serine protease involved in processing of insulin like growth factor binding protein (ICFBP), indicating that it serves as an important regulator of IGF activity. Additionally, several lines of evidence suggest a striking correlation between proteolytic activity of HtrA1 serine protease and the pathogenesis of several diseases; however, physiological roles of HtrA1 remain to be elucidated. We used the pGEX bacterial expression system to develop a simple and rapid method for purifying HtrA1, and the recombinant HtrA1 protein was utilized to investigate the optimal conditions in executing its proteolytic activity. The proteolytically active HtrA1 was purified to approximately 85% purity, although the yield of the recombinant HtrA1 protein was slightly low $460{\mu}g$ for 1 liter E. coli culture). Using in vitro endoproteolytic cleavage assay, we identified that the HtrA1 serine protease activity was dependent on the enzyme concentration and the incubation time and that the best reaction temperature was $42^{\circ}C$ instead of $37^{\circ}C$. We arbitrary defined one unit of proteolytic activity of the HtrA1 serine protease as 200nM of HtrA1 that cleaves half of $5{\mu}M\;of\;{\beta}-casein$ during 3 hr incubation at $37^{\circ}C$. Our study provides a method for generating useful reagents to investigate the molecular mechanisms by which HtrA1 serine protease activity contributes in regulating its physiological function and to identify natural substrates of HtrA1.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.7 no.2
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• pp.27-34
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• 2013

Most of existing biomedical signal measurement devices measure and evaluate biomedical signal only in a single device. Also, even if the device is multi-functional, those biomedical signals can be measured by selection of the user. In this paper, we implemented wristband-style biomedical signal measurement device for u-healthcare system to solve the problem above. Implemented device uses 4 infrared sensors to measure the pulse, 2 electrodes to measure the skin conductivity, and 3-axis accelerometer to measure momentum. Also, we propose a communication packet frame for transmitting biomedical signal data to PC or mobile device, using Zigbee. Studies show that our device has the error rate of less than twice for pulse measurement, 85.6%, 84.7% reliability for momentum measurement, and the skin conductivity has changed according to the user's physical status.

• The Transactions of the Korean Institute of Power Electronics
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• v.4 no.5
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• pp.462-473
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• 1999

This paper addresses the current measurement issue of all digital field oriented control of ac motors. The p paper focuses on the effect of low-pass filter and also on the sampling of the fundamental component of the m motor current. The low-pass filter, which suppresses the switching noise of the motor current, introduces v variable phase delay according to the current ripple frequency. It is shown that the current sampling error c consists of the fundamental component and high frL'quency ripple components. In this paper, the dependency of t this current sampling e$\pi$or on the reference voltage vector is investigated analytically and a sampling technique i is proposed to minimize the error. The work is based on the three phase symmetry pulse width modulation l inverter driving an induction machine. With this technique, the bandwidth of current regulator can be extended t to the limit given by the switching frequency of the inverter and more precise torque regulation is possible.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 1994.04a
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• pp.94-99
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• 1994

최근 인구의 과밀화와 이에 따른 지가의 상승 등으로 대표적인 주거용 빌딩인 아파트의 고층화가 급속하게 진행되고 있고 아파트에 설치되는 엘리베이터도 점차 대형화, 고속화 되고 있다. 실례로 15층 아파트의 경우 11인승, 60m/min의 엘리베이터가 일반적으로 사용되는 반면, 20층 아파트의 경우 17인승, 90m/min이 주로 사용된다. 이와 같이 엘리베이터의 용량과 운행 속도가 증가함에 따라 필연적으로 소음 및 진동 문제가 발생하게 된다. 특히 아파트의 경우 침실, 공부방 등 고도의 정숙을 요하는 생활 공간이 많고, 내부 공간의 활용도를 높이기 위하여 이들 방들이 엘리베이터 기계실 또는 운행 통로와 직접 접하여 있는 경우도 있어 이 경우 소음, 진동 문제는 아주 심각한 문제로 대두된다. 본 연구소가 측정한 방에 의하면 S신도시 L아파트의 경우 아파트 최상층 방에서 실내 소음도가 46dB(A), 벽의 진동가속도가 3.4mm/s$^{2}$(RMS)으로 나타났다. 진동의 경우 생활에 직접적인 악영향을 미칠 수준은 아니지만 소음의 경우 ASHRAE 권장 주택소음 기준치가 35dB(A) 이하임ㅇㄹ 감안하면 주거에 곤란한 수준이다. 수년전, 고층 아파트가 보급될 초기에는 아파트에 엘리베이터가 설치되어있다는 그 자체만으로 충분한 장점이 되어 다소음 소음, 진동문제는 큰 불만거리가 되지 않았지만 엘리베이터가 보편화된 지금에는 엘리베이터의 편리성만으로는 점점더 크게 요구되는 정숙성이 보상되지 않는다. 따라서 전반적인 아파트의 소음, 진동 문제에 큰 비중을 차지하는 엘리베이터에 의한 소음, 진동에 관하여 체계적인 연구가 필요하다. 이에 본고에서는 엘리베이터에 의한 아파트의 소음 및 진동에 관하여 그 현황, 원인 그리고 대책에 관한여 논하고자 한다.감 방법을 연구하였고, T.Sakai는 5자유도 모델을 이용하여 엔진 공회전시 발생하는 치타음에 대해 이론과 실험을 통해 해석하고, 엔진 회전수 변동, 클러치 특성, 변속기의 드래그(drag) 토크의 영향과 치타음 저감을 위한 개선된 클러치 특성을 제시하였다. 이 외에도 Thomas C.T.와 E.P.Petkus는 특정 차량에 대한 동력전달계의 비틀림 진동 현상에 대해 연구하였다. 이러한 연구들로 볼 때, 자동차 동력전달계에서 발생하는 진동은 이론과 실험을 통해 그 해석이 가능하며 설계에 매우 유용하게 이용되고 있음을 알 수 있다. 따라서, 본 연구는 4 실린더 4 싸이클 1.5 L 엔진을 장착한 경승용차의 실차 주행실험을 통해 가속 페달의 급조작에 따른 차체의 종진동 현상을 측정하고, 엔진-변속기-타이어-차체의 반환정계 4자유도 진동모델로 시뮬레이션을 수행하여 실차 주행실험의 결과치와 비교, 분석한 후 클러치 비틀림 특성을 비롯한 자동차 동력전달계의 각 설계인자들이 차체의 종진동에 어떠한 영향을 미치는가를 해석하고자 한다.be presented.LIFO, 우선 순위 방식등을 선택할 수 있도록 확장하였다. SIMPLE는 자료구조 및 프로그램이 공개되어 있으므로 프로그래머가 원하는 기능을 쉽게 추가할 수 있는 장점도 있다. 아울러 SMPLE에서 새로이 추가된 자료구조와 함수 및 설비제어 방식등을 활용하여 실제 중형급 시스템에 대한 시뮬레이션 구현과 시스템 분석의 예를 보인다._3$", chain segment, with the activation energy of carriers from the shallow trap with 0.4[eV], in he amorphous regions.의 증발산율은 우기의 기상자료를 이용하여 구한 결과 0.05 - 0.1

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2005.05a
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• pp.135-138
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• 2005

현재 널리 상용되어 있는PDP는 3전극 변방전형이다. 3전극 면장전형 PDP는 주방전이 유전체 아래에 서로 평행하게 위치하고 있는 ITO투명전극 사이에서 발생한다. 따라서 방전시의 전기장은 MgO 보호막 위에서 아치형태로 형성되게 된다. 플라스마 방전 시 전자에 의해 이온화된 이온 입자들은 전기장에 의해 그 방전경로가 정해지게 된다. 물론 전기장은 표면에서 수직이지만 전기장에 의해 가속되어진 이온입자들은 MgO 보호막에 기울어져서 입사하게 된다. 따라서 플라스마 방전시의 이온들의 MgO 보호막으로의 입사각은 매우 다양하다. $\gamma$-FIB (Focused ion beam) 시스템은 이온입사에 의한 물질의 이차전자방출계수 측정에 효과적인 장비이다. 본 실험은 이러한 $\gamma$-FIB 시스템을 이용하여 다양한 각도로 입사하는 이온빔에 의한 MgO 보호막의 이차전자방출계수를 측정하였다. 또한 이온화 에너지가 다른 여러 종류의 불활성 기체를 사용하여 이온의 입사하는 각도에 따른 MgO 보호막의 일함수를 측정하였다. 이온빔의 입사각은 각각 $0^{\circ}$, $10^{\circ}$, $20^{\circ}$, $30^{\circ}$로 변화시키면서 이차전자방출계수 및 일함수를 측정하였다. 이러한 실험을 통해 입사각이 클수록 이차전자방출계수는 증가하고 일수는 감소하는 것을 확인 할 수 있었다.

• Korean Journal of Poultry Science
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• v.33 no.1
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• pp.57-63
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• 2006

This study was conducted to investigate the effect of ventilating system of environmental controlled broiler house on broiler production. Three hundred eighty four broiler chicks (Hubbard, mean live weight of $44.5{\pm}2.0g/bird$) were reared for 2 wk. The results of the present study were summarized as follows : 1. Ammonia gas production was lower in the second and the third floors of cages compared with first floor of cages 13.5 and 13.5 vs 14.6 ppm, respectively). The observations of ammonia production in the morning and afternoon were similar. The production of carbon dioxide was not different between morning and afternoon, but it was tended to decrease in the forth floor of cages due to a fresh air 2. A wind velocity in the enclosed house was similar across lower, middle and upper section (0.57m/sec, 0.22m/sec and 0.04msec, respectively). In order to maintain an optimal air flow velocity in the cages, the duct entrance was punched, and then the air flow was full-round in the overall space in the cage. 3. Daily liveweight gain, feed intakes, and feed efficiency were not significant differences among treatments during whole experimental period (P>0.05). Therefore, the present results showed that temperature, moisture and atmosphere controlling were desirable, and air flew evenly in the cage.

• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.3
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• pp.418-427
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• 2003

Conjugated linoleic acid (CLA) is the mixture of positional and geometric isomers of linoleic acid (LA, C18:2 $\omega$6), which is found abundantly in dairy products and meats. This study was peformed to investigate the anticarcinogenic effect of CLA in MCF-7 breast cancer cells. MCF-7 cell were treated with LA and CLA at the various concentrations of 15, 30, 60, 120 UM each. After incubation for 48 and 72 hours, cell proliferation, fatty acids incorporation into cell, peroxidation and activities of antioxidant enzymes were measured. Postaglandin E$_2$ (PGE$_2$) and thromboxane $A_2$ (TXA$_2$) were measured for the eicosanoids metabolism. There was no cell growth differences in both of LA and CLA treated MCF-7 cells at 48 hr incubation. Compared to LA, cell growth was decreased by CLA treatment according to increasing concentration at longer incubation times, respectively (p<0.05). Both of LA and CLA was incorporated into the cellular lipids 22~54% higher than in control but LA incorporation was not so linear as CLA according to concentration. Arachidonic acid (C20:4, $\omega$6) was synthesized after treatment of LA but did not in CLA, respectively. The lipid peroxide concentration in LA 120 $\mu$M group increased as 1.7 times as that in CLA 120 $\mu$M treated. The activities of antioxidant enzymes such as glutathione peroxidase and glutathione reductase were increased by the supplementation with CLA 120 $\mu$M at 72 hr incubation (p<0.001) compared to LA, otherwise activity of superoxide dismutase was not different in both. PGE$_2$ and TXA$_2$ levels were lower in condition of CLA treatments according to lower levels of arachidonic acids than those in LA treated group, respectively. Overall, the dietary CLA might change the MCF-7 cell growth by the changes of cell composition, production of lipid peroxide, activities of antioxidant enzymes and eicosanoid synthesis compared to dietary LA.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.9 no.2
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• pp.89-103
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• 2015

The purpose of this research attempted to developed the Community Reintegration support Program(H-CRsP) on patients with Spinal Cord Injury(SCI) and identity the effect. To assess the effectiveness of a Hospital based H-CRsP with a comprehensive team approach for treating inpatients with Spinal Cord Injury(SCI), offered by the Korea National Rehabilitation Hospital. Participants with SCI were recruited from the Korean National Rehabilitation Hospital. Twenty-five participants who met inclusion criteria were provided with a H-CRsP. A H-CRsP with modules related to the training of daily living skills, driving, vocations and school support activities, leisure or recreational activities, peer counseling, sexual rehabilitation, and others support activities. The 25 enrolled patients had been treated with average of 6.1 programs 2 times a week for over 2 or 3months. COPM, HADS, WHOQOL-BREF, AD-R were administered before the treatment(pre-test) and also at the time of discharge(post-test) to compare the treatment outcomes in the 25 program participants. Measured level of community integration by CIQ at discharge. The data were analyzed by such statistical methods as frequency and paired t-test analysis. Significant improvements were found on the Occupational Performance and Satisfaction, Acceptance of Disability, Quality of Life score in the COPM, AD-R, WHOQOL-BREF (p<0.05). In addition, 10 of the 25 patients returned to home, work or school. These results demonstrated the effectiveness of the H-CRsP in helping patients with SCI return their communities to which they belong. It considered development of the variety of programs and prepare systematically related system.

• Journal of Animal Environmental Science
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• v.16 no.3
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• pp.205-215
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• 2010

Geothermal heat pump system (GHPS) is an energy-efficient technology that use the relatively constant and renewable energy stored in the earth to provide heating and cooling. With the aim of using GHPS as a heating source, it's possibilities of application in farrowing house were examined by measuring environmental assessment and sow's performance. A total of 96 sows were assigned to 2 pig housings (GHPS and conventional housing) with 48 for four weeks in winter season. During the experimental period, indoor maximum temperature in GHPS-housing was measured up to $26.7^{\circ}C$, average temperature could maintain $21.2^{\circ}C$. The mean value of dust levels and $CO_2$, $NH_3$ and $H_2S$ gas emissions were decreased in GHPS-housing compare with those of conventional housing. Litter size, birth weight, parity and weaning weight did not differ between housings. However, feed intake of sow in GHPS-housing was lower than that of conventional housing. In energy consumption for heating, electric power consumption increased in GHPS-housing than the conventional housing, a 2,250 kwh increase, whereas there is no fuel usage for heater in GHPS-housing. Amount of ground water circulated for heating in cold weather for earth heat exchanger was 8.4-12.9 ton per day. In conclusion, GHPS may have environmental benefits and effectiveness of heating in farrowing housing and affect the performance in sows.