• Journal of Digital Convergence
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• v.13 no.5
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• pp.227-235
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• 2015

In order to tackle healthcare expenditure problems that affects a crucial part of government finances world-wide, m-Health emerged as a solution. However, recent poor outcomes of m-Health led to the need for reform in m-Health services. Therefore the purpose of this research is to propose a solution for efficient vital data transmission and storing in m-Health environment as part of such initiative. Methods included development of an efficient system and algorithm for vital data. For results, the compression ratio of the proposed solution was compared and evaluated. Results showed a compression ratio of 30.4. The proposed system is envisioned to contribute to the future vital data monitoring system in m-Health.

• Korean Journal of Clinical Pharmacy
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• v.29 no.2
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• pp.101-108
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• 2019

Background: High doses of methotrexate (MTX) are often used in various chemotherapy protocols to treat acute lymphoblastic leukemia (ALL) and non-Hodgkin's lymphoma (NHL) in children, but its delayed elimination increases the occurrence of adverse events, such as bone marrow suppression. The aim of this study was to investigate the elimination of MTX at 24 and 48 hours. Methods: We retrospectively analyzed electronic medical records of ALL or NHL pediatric patients who received $5g/m^2$ MTX infusion over 24 hours (between June, 2012 and July, 2018) at the Yonsei University Health System, Korea. The delayed elimination of MTX concentrations was assessed with 100 or $150{\mu}M$ MTX at 24 hours, and 2 or $5{\mu}M$ at 48 hours. Results: Among the 85 MTX cycles administered, 23 cycles were classified in delayed elimination group, and 62 cycles showed normal elimination. At 24 hours, the delayed elimination group with MTX concentration > $100{\mu}M$ showed higher percentage than group with MTX concentration < $100{\mu}M$ (45.8% vs. 19.7%, p = 0.015). However, no differences were observed at $150{\mu}M$ MTX (p = 0.66). At 48 hours, the delayed elimination was higher than the normal elimination at both concentration baselines (p < 0.001 at $2{\mu}M$, p = 0.024 at $5{\mu}M$). Conclusions: MTX concentrations greater than $100{\mu}M$ show high probability of delayed elimination at 24 hours. When MTX levels are above normal, leucovorin and hydration regimens should be continued to prevent delayed elimination.

• Journal of the Korea Society of Computer and Information
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• v.17 no.7
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• pp.97-106
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• 2012

Management of biosignal data in mobile devices causes many problems in real-time transmission of large volume of multimedia data or storage devices. Therefore, this research paper intends to suggest an m-Health system, a clinical data processing system using mobile in order to provide quick medical service. This system deployed health system on IP network, compounded outputs from many bio sensing in remote sites and performed integrated data processing electronically on various bio sensors. The m-health system measures and monitors various biosignals and sends them to data servers of remote hospitals. It is an Android-based mobile application which patients and their family and medical staff can use anywhere anytime. Medical staff access patient data from hospital data servers and provide feedback on medical diagnosis and prescription to patients or users. Video stream for patient monitoring uses a scalable transcoding technique to decides data size appropriate for network traffic and sends video stream, remarkably reducing loads of mobile systems and networks.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2009.10a
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• pp.866-870
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• 2009

Mobile Health (M-Health) system is a recent term for medical and public health practice supported by mobile devices, such as mobile phones, PDAs, and other wireless devices. Mobile Health system has been successfully establishing at few general hospital in Korea. However, to use diverse devices manufactured by various company cause inoperability, and lack of security disappoints customers often. Although the outstanding health environment, most of hospitals are unavailable to share electronic patient records due to lack of standard protocol to handle the interoperability each other. Health Level 7 (HL7) is the best solution for the problem. In this paper, we will analyse a current M-Health service in terms of security and mobile device, and suggest iPhone for the best device against hospital environment. Also, for keep confidentiality of health information and patient privacy, enhanced security mechanism is introduced. As a consequence, interoperable standard, and most appropriate device for supporting staffs and M-Health performance, and enhanced securirty mechanism will be integrated in order to propose improved M-health model.

• Nuclear Medicine and Molecular Imaging
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• v.43 no.1
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• pp.48-54
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• 2009

Purpose: There are few studies evaluating the usefulness of dedicated high-resolution scintimammography and no studies using delayed washout with this dedicated high resolution scintimammography for the evaluation of breast lesions. We underwent this study to evaluate the clinical usefulness of Tc-99m MIBI in evaluating patients with palpable breast lesions using dedicated high-resolution scintimammography. Materials and Methods: This study included 19 patients with 23 palpable breast lesions who underwent mammography. Tc-99m MIBI was taken to further characterize these lesions. Scintimammography images were acquired with standard craniocaudal and mediolateral oblique views and delayed images were additionally taken. Final conclusions were based on histopathology, either by biopsy or mastectomy results. Results: Eighteen lesions were malignant and five were benign. Mammography was indeterminate for thirteen lesions, nine of those were malignant. Mammography also categorized one lesion as benign in a dense breast, but scintimammography and pathology results showed malignancy. Of the five benign lesions, two were visible on scintimammography, but delayed images showed washout. Conclusion: Based on our preliminary results, dedicated high resolution scintimammography seems to be very useful in characterizing palpable lesions that were indeterminate or negative on mammography.

• Progress in Medical Physics
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• v.18 no.3
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• pp.134-138
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• 2007

The current PET/CT system with high quality CT images not only increases diagnostic value by providing anatomic localization, but also shortens the acquisition time for attenuation correction than primary PET system. All commercially available PET/CT system uses the CT scan for attenuation correction instead of the transmission scan using radioactive source such as $^{137}Cs,\;^{68}Ge$. However the CT scan may substantially increase the patient dose. The purpose of this study was to evaluate quality of PET images reconstructed by CT attenuation map using various tube currents. in this study, images were acquired for 3D Hoffman brain phantom and cylindrical phantom using GE DSTe PET/CT system. The emission data were acquired for 10 min using phantoms after injecting 44.03 MBq of $^{18}F-FDG$. The CT images for attenuation map were acquired by changing tube current from 10 mA to 95 mA with fixed exposure time of 8 sec and fixed tube voltage of 140 kVp. The PET images were reconstructed using these CT attenuation maps. Image quality of CT images was evaluated by measuring SD (standard deviation) of cylindrical phantom which was filled with water and $^{18}F-FDG$ solution. The PET images were evaluated by measuring the activity ratio between gray matter and white matter in Hoffman phantom images. SDs of CT images decrease by increasing tube current. When PET images were reconstructed using CT attenuation maps with various tube currents, the activity ratios between gray matter and white matter of PET images were almost same. These results indicated that the quality of the PET images using low dose CT data were comparable to the PET images using general dose CT data. Therefore, the use of low dose CT is recommended than the use of general dose CT, when the diagnostic high quality CT is not required. Further studies may need to be performed for other system, since this study is limited to the GE DSTe system used in this study.

• Proceedings of the Korean Environmental Health Society Conference
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• 2005.06a
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• pp.381-385
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• 2005

Characterization of particle behavior is becoming more important in performance evaluation of water treatment system as well as in operation of the system because conventional parameter, turbidity has lack of explaining ability on small sized microorganisms such like Cryptosporidium etc. Accordingly, particle counter has been introduced in evaluation and operation of the treatment system. However researches on the relationship between turbidity, particle count and/or different sand/anthracite sizes have not been concurrent. Therefore in this study, the relationship was investigated to improve performance evaluation of sand filter so as to help choosing sand/anthracite effective size as a design parameter of water treatment facility. According to the results, too small or too large effective size media filter reached to turbidity limit(0.1 NTU)earlier. However, because shallow sand layer may cause early breakthrough, the depth of sand layer should be provided enough in order to compromise water quality and productivity.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.11 no.1
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• pp.1-8
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• 2001

This study was performed to evaluate a local exhaust ventilation system capability and welding fume concentration in welding laboratory at 5 technical high schools. Results of the study are as follows; 1. The personal exposure of welding fume in welding laboratory was measured. The geometric mean of 73 personal samples was $6.27mg/m^3$($3.85{\sim}9.88mg/m^3$), and 68.5% of these exceeded TLV of the Korea Ministry of Labor. 2. The geometric mean of welding fume at outside of booth was $2.27mg/m^3$($1.57{\sim}2.58mg/m^3$). All of measured concentrations were lower than TLV of the Korea Ministry of Labor. 3. Local exhaust ventilation system in welding laboratory could not remove hazardous substance effectively because of inappropriate canopy hood and absurd design. 4. The possibility of exposure risk was estimated to be high because of working point under breathing zone, misplacement of working table and insufficient supply of respiratory protector. 5. The mean values of capture velocity and transportation velocity of local exhaust ventilation system in welding laboratory were 0.38m/sec, 4.27m/sec respectively. These values were satisfied the guideline of the Korea Ministry of Labor. 6. The efficiency of performance of local ventilation system was anticipated to be decreased because of accumulated dust and alien substance on fan and duct.

• Smart Structures and Systems
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• v.11 no.6
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• pp.637-662
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• 2013

The Jiangyin Bridge is a suspension bridge with a main span of 1385 m over the Yangtze River in Jiangsu Province, China. Being the first bridge with a main span exceeding 1 km in Chinese mainland, it had been instrumented with a structural health monitoring (SHM) system when completed in 1999. After operation for several years, it was found with malfunction in sensors and data acquisition units, and insufficient sensors to provide necessary information for structural health evaluation. This study reports the SHM system upgrade project on the Jiangyin Bridge. Although implementations of SHM system have been reported worldwide, few studies are available on the upgrade of SHM system so far. Recognizing this, the upgrade of original SHM system for the bridge is first discussed in detail. Especially, lessons learned from the original SHM system are applied to the design of upgraded SHM system right away. Then, performance assessment of the bridge, including: (i) characterization of temperature profiles and effects; (ii) recognition of wind characteristics and effects; and (iii) identification of modal properties, is carried out by making use of the long-term monitoring data obtained from the upgraded SHM system. Emphasis is placed on the verification of design assumptions and prediction of bridge behavior or extreme responses. The results may provide the baseline for structural health evaluation.

• The Korean Journal of Nuclear Medicine Technology
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• v.14 no.2
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• pp.9-16
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• 2010

Purpose: With increasing medical use of radiation and radioactive isotopes, there is a need to better manage the risk of radiation exposure. This study aims to grasp and analyze the individual radiation exposure situations of radiation-related workers in a medical facility by specific job, in order to instill awareness of radiation danger and to assist in safety and radiation exposure management for such workers. Materials and Methods: 1 January 2007 to 31 December 2009 to work in medical institutions are classified as radiation workers Nuclear personal radiation dosimeter regularly, continuously administered survey of 40 workers in three years of occupation to target, Imaging Unit beautifully, age, dose sector, job function-related tasks to identify the average annual dose for a deep dose, respectively, were analyzed. The frequency analysis and ANOVA analysis was performed. Results: Imaging Unit beautifully three years the annual dose PET and PET/CT in the work room 11.06~12.62 mSv dose showed the highest, gamma camera injection room 11.72 mSv with a higher average annual dose of occupation by the clinical technicians 8.92 mSv the highest, radiological 7.50 mSv, a nurse 2.61 mSv, the researchers 0.69 mSv, received 0.48 mSv, 0.35 mSv doctors orderly, and detail work employed the average annual dose of the PET and PET/CT work is 12.09 mSv showed the highest radiation dose, gamma camera injection work the 11.72 mSv, gamma camera imaging work 4.92 mSv, treatment and safety management and 2.98 mSv, a nurse working 2.96 mSv, management of 1.72 mSv, work image analysis 0.92 mSv, reading task 0.54 mSv, with receiving 0.51 mSv, 0.29 mSv research work, respectively. Dose sector average annual dose of the study subjects, 15 people (37.5%) than the 1 mSv dose distribution and 5 people (12.5%) and 1.01~5.0 mSv with the dose distribution was less than, 5.01~10.0 mSv in the 14 people (35.0%), 10.01~20.0 mSv in the 6 people (15.0%) of the distribution were analyzed. The average annual dose according to age in occupations that radiological workers 25~34 years old have the highest average of 8.69 mSv dose showed the average annual dose of tenure of 5~9 years in jobs radiation workers in the 9.5 mSv The average was the highest dose. Conclusion: These results suggest that medical radiation workers working in Nuclear Medicine radiation safety management of the majority of the current were carried out in the effectiveness, depending on job characteristics has been found that many differences. However, this requires efforts to minimize radiation exposure, and systematic training for them and for reasonable radiation exposure management system is needed.