• Title/Summary/Keyword: M-continuous

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A Phase II Study on Continuous Infusional Paclitaxel and 5-Fu as First-line Chemotherapy for Patients with Advanced Esophageal Cancer

  • Gu, Ming;Li, Su-Yi;Huang, Xin-En;Lin, Yan;Cheng, Hong-Yan;Liu, Lin
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.11
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    • pp.5587-5591
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    • 2012
  • Objective: This study was performed to evaluated the efficacy and safety of continuous infusional paclitaxel and 5-Fu as first-line chemotherapy in patients with advanced esophageal squamous cell cancer (ESCC). Methods: A total of 22 patients with advanced esophageal squamous cell cancer with no indications for surgery and radiation therapy, or recurrent patients were enrolled from October 2008 to November 2010. All were treated with PTX 20 $mg/m^2$ was administered through a 16 hours continuous intravenous infusion on days 1 to 3, 8 and 9. DDP 3.75 $mg/m^2$ was given on days 1 to 4 and 8 to 11, continuous infusional 5-FU over 24-hours on days 1 to 5 and 8 to 12 at a dose of 375 $mg/m^2$, and folacin 60 mg orally synchronized with 5-Fu. The treatment was repeated every 21 days for at least two cycles. Results: 22 cases of all enrolled patients could be evaluated for the effect of treatment: 2 cases were CR, 9 cases PR, 5 cases SD and 2 cases PD, giving an overall response rate of 68.2%(15/22). The median time to progression was 7.0 months. The adverse reactions related to chemotherapy were tolerable; the most common toxic effects were marrow depression, alopecia, and fatigue. Conclusion: Low-dose continuous infusional PTX over 16-hours and 5-fu over 24-hours is a promising regimen with good tolerability in treating patients with advanced esophageal squamous cell cancer.

Estimation of Carrying Capacity by Food Availability for Farming Oysters in Goseong Bay, Korea (먹이가용성에 의한 고성만의 굴 양식장 수용력)

  • Lee, Sang-Jun;Jeong, Woo-Geon;Cho, Sang-Man;Kwon, Jung No
    • The Korean Journal of Malacology
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    • v.32 no.2
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    • pp.83-93
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    • 2016
  • For the continuous stable production of oyster, estimation of food availability (F) was carried out in Goseong Bay, south of coast Korea. Primary productivity ranged from 0.07 to $0.44gC/m^2/day$ (average $0.25gC/m^2/day$), lowest in July and highest in January. The distribution of primary productivity at Goseong Bay showed the pattern of "high in the south and low in the north." Food availability (F) was $F{\leq}0$, indicating insufficient food supply, from August to November and F > 0 from January to April. Continuous insufficient food supply was observed at 18 oyster farms in the southern part of the bay and 4 in its northern part. Mortality at the oyster farms was 56% on the average, and around 58% of death occurred during November when food supply was insufficient. The optimal population of cultured oyster per unit flow area was calculated to be $110-115indiv./m^2$ (198-201 indiv./string). When the sea area was divided into 3 regions (A, B, C) according to carrying capacity, the carrying capacity of (A) regions was $52-53indiv./m^2$ (93-95 indiv./string), (B) regions was $142-144indiv./m^2$ (255-259 indiv./string), and (C) regions was $198-202indiv./m^2$ (356-363 indiv./string). In particular, (A) regions showed extremely low productivity. For continuous stable oyster farming at Goseong Bay, it is necessary to control point and non-point source pollution through continuous environmental monitoring and to adjust harvest according to the base carrying capacity during the season of high water temperature.

Anaerobic Digestion Treatment for the Mixture of Chinese Cabbage Waste Juice and Swine Manure

  • Kafle, Gopi Krishna;Kim, Sang-Hun;Shin, Beom-Soo
    • Journal of Biosystems Engineering
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    • v.37 no.1
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    • pp.58-64
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    • 2012
  • Purpose: The objective of this study was to investigate the feasibility of anaerobic digestion of Chinese cabbage waste juice (CCWJ) and swine manure(SM). Methods: The anaerobic digestion test was conducted under batch and continuous conditions at mesophilic temperature ($36-38^{\circ}C$). The batch test was divided into Experiment I and II. In the Experiment I, biogas potential and production rate of CCWJ was evaluated. In Experiment II the effect of F/M ratio (2.0, 3.2, 4.9) at mixture ratio of 25:75(CCWJ: SM, % vol. basis) on biogas yield was studied. Results: CCWJ produced biogas and methane yield of 929 and 700 mL/g VS added respectively. The biogas yield from the mixture of CCWJ and SM was almost same at F/M ratio of 2.0 and 3.2 but dropped by 14% when F/M ratio increased from 3.2 to 4.9. In continuous test the mixture of CCWJ and SM (25:75, % vol. basis) produced biogas yield of 352 mL/g VS added which is around 11% higher compared to biogas yield from SM alone. Addition to biogas yield digester performance was also improved with co-digestion of CCWJ with SM. Conclusions: The results showed that the anaerobic digestion of CCWJ with SM could be promising for improving both the biogas yield and digester performance at mesophilic temperature.

m-SEMIOPEN SETS AND M-SEMICONTINUOUS FUNCTIONS ON SPACES WITH MINIMAL STRUCTURES

  • Min, Won-Keun
    • Honam Mathematical Journal
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    • v.31 no.2
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    • pp.239-245
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    • 2009
  • In this paper, we introduce the notions of m-semiopen sets and M-semicontinuous functions on spaces with minimal structures and study some properties of such notions. In particular, we investigate characterizations for the M-semicontinuous function and the relationship between M-continuity and M-semicontinuity.

Performance of Self-Manufactured Ion Selective Microelectrode (ISME) for Continuous Monitoring of Ammonia and Nitrate Ions

  • Byun, Im-Gyu
    • Journal of Environmental Science International
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    • v.21 no.12
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    • pp.1449-1454
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    • 2012
  • The ion selective microelectrodes (ISME) have been applied to observe the continuous profiles of NO3-N and NH4-N in bulk solutions or biofilms. In order to evaluate the performance and applicability of ion concentration measuring system, the characteristics, such as slope of calibration curve, detection limit and potentiometric selectivity coefficient were investigated. The slopes of calibration curve showed high degree of correspondence for each target ion concentrations. And the detection limits of nitrate and ammonia ion selective microelectrode were 10-4.7 M and 10-4.4 M, respectively. These ion selective microelectrodes were proved that their own performance could be maintained for 16 days after making. NO3-N and NH4-N selective microelectrodes were also adapted to detect the continuous ion profiles of cilia media packed MLE (Modified Ludzack-Ettinger) process. And the monitored nitrate and ammonia ion profiles with the ion selective microelectrode were stable and well corresponded to the results with conventional ion chromatograph. However, the electric potential was unstable until 8 hr because of the unknown noise. The tip shape and performance of the ion selective microelectrode was stably kept over 2 days continuous monitoring.

Change in Microstructure and Texture during Continuous-Annealing in Dual-Phase Steels (복합조직강의 연속어닐링과정에서 미세조직과 집합조직의 변화)

  • Jeong, Woo Chang
    • Journal of the Korean Society for Heat Treatment
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    • v.28 no.4
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    • pp.171-180
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    • 2015
  • The variation in microstructure and texture during continuous annealing was examined in a series of 1.6% Mn-0.1% Cr-0.3% Mo-0.005% B steels with carbon contents in the range of 0.010 to 0.030%. It was found that microstructure of hot band consisted of ferrite and pearlite as a consequence of high coiling temperature, and eutectoid carbon content was between 0.011% and 0.016%. Martensite ranged in volume fraction from 1.5% to 4.0% when annealed at $820{\circ}C$ according to the typical continuous annealing cycle. The critical martensite content for the continuous yielding was about 4% from stress-strain curves. The continuous yielding was obtained in the 0.030% carbon steel and 0.010% to 0.020% carbon steels revealed some yield point elongation ranging from 0.8% to 2.2% in as-annealed conditions. Higher tensile strength in the higher carbon steel is due to both increase in the martensite volume fraction and ferrite grain refinement. Decreasing the carbon content to 0.01% strengthened the intensities of ${\gamma}$-fiber textures, resulting in the increase in the $r_m$ value, which was caused by the lower volume fraction of martensite. The higher carbon steels showed the lower $r_m$ value of about 1.0.

Electrohydrodynamic Continuous Jet Printing of Ni Ink for Crystalline Silicon Solar Cells (전기 수력학 인쇄공정을 이용한 실리콘 태양전지 전극용 Ni 잉크 제조 및 인쇄 공정 연구)

  • Lee, Youngwoo;Kim, Jihoon
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.28 no.9
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    • pp.593-597
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    • 2015
  • Ni ink for electrohydrodynamic (EHD) continuous jet printing has been developed by using Ni nanoparticles mixed with conhesiveness provider. EHD continuous jet printing was used in order to realize $20{\mu}m$ pattern width. Ink stability was investigated by using Turbi-scan which monitors agglomeration and precipitation of nanoparticles in the ink for three days. The Turbi-scan results showed that the formulated Ni ink had been stable for 3 days without any indication of precipitation across the entire ink. Antireflection coating (ARC) layer in crystalline solar cell wafers was removed by laser ablation technique leading to the formation of 84 grooves where the Ni ink was printed by EHD continuous jet printing. The printability and microstructure of EHD-jet-printed Ni lines were investigated by using optical and electron microscopes. 84 Ni lines with the width less than $20{\mu}m$ were successfully printed by one-time printing without any misalignment and fill the laser-ablated ARC grooves.

ON M-CONTINUITY

  • Min, Won Keun;Chang, Hong Soon
    • Korean Journal of Mathematics
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    • v.6 no.2
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    • pp.323-329
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    • 1998
  • In this paper, we introduce a new class of sets, called $m$-sets, and the notion of $m$-continuity. In particular, $m$-sets and $m$-continuity are used to extend known results for ${\alpha}$-continuity and semi-continuity and precontinuity.

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ON MINIMAL PRECONTINUOUS FUNCTIONS

  • Min, Won Keun;Kim, Young Key
    • Journal of the Chungcheong Mathematical Society
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    • v.22 no.4
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    • pp.667-673
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    • 2009
  • In this paper, we introduce the notions of minimal precontinuity, m-preclosed graph, almost m-precompact and m-precompact and investigate some properties for such notions.

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