• Journal of Animal Science and Technology
• /
• v.63 no.4
• /
• pp.919-933
• /
• 2021

We hypothesized that the unsaturated fatty acid palmitoleic acid (POA) could promote the expression of adipogenic/lipogenic genes in bovine skeletal muscle satellite cells (BSCs). The BSCs were cultured in a growth medium containing 10% fetal bovine serum. When the cells reached 80%-90% confluence, we used the differentiation medium with 5% horse serum for differentiation for 96 h. The differentiation medium contained 50 µM, 100 µM and 200 µM POA. Control BSC were cultured only in differentiation media. Compared with the control BSC, the POA BSC significantly up-regulated the expression of paired box 3 (Pax3) and paired box 7 (Pax7) and down-regulated myogenin gene expression (p < 0.01), which indicates a depression in muscle fiber development. However, all POA treatments up-regulated the expression of the adipocyte transcription factors peroxisome proliferator-activated receptor γ (PPARγ), CCAAT/enhancer-binding protein alpha and beta (C/EBP α and C/EBP β), and other genes (p < 0.01) and increased the expression of PAT-family proteins and the concentration of adiponectin in the media. These results indicate that POA can convert part of BSCs into adipocytes.

• 한국정보디스플레이학회:학술대회논문집
• /
• 2008.10a
• /
• pp.1001-1004
• /
• 2008

An advanced backplane circuit technology for AMOLED using amorphous silicon TFTs with commercial level reliability, uniformity and lifetime was recently integrated into a prototype device. Differential aging of T98>100 hrs at 200 cd/m2 brightness and >10,000hrs lifetime is demonstrated. A 2.2" QVGA ($240{\times}320$) prototype has been developed and shown having the above-mentioned high performance.

• Information Systems Review
• /
• v.11 no.1
• /
• pp.145-160
• /
• 2009

Based on the user-centered innovation theory of von Hippel (2005), this research seeks to provide a case study of user innovation in the automobile navigation industry, which is a representative applied service in the area of Location-Based Service (LBS). The automobile navigation development and maintenance/repair processes of M&Soft are analyzed around the seven characteristics of user innovation as outlined by von Hippel. As a result, among the three strategic responses of sellers in the successful utilization of user innovation, it was determined that the approach of M&Soft was limited to providing an easy-to-use information technology platform so as to encourage members to easily share all types of map or mobile information or ideas. The significance of this paper is in that the theory of von Hippel originally based on physical products was applied to digital ones in line with the trend of increasing importance of Internet-based content services.

• Korean Management Science Review
• /
• v.34 no.1
• /
• pp.27-45
• /
• 2017

The purpose of this study is to empirically analyze whether open innovation activities are significant and which methods are more effective in developing new businesses. Based on the latest technological innovation survey data of the Science and Technology Policy Institute, the results were analyzed by binary logistic regression analysis. As a result of the analysis, we confirmed that open innovation activities have a positive effect on the performance of developing new businesses. In the open innovation activities, Recruitment (invitation) of specialist in related fields, Business alliance technical agreement, Dispatch of personnel, M&A, Acquisitions identify related field trends showed more influence in order. It would be beneficial to improve the performance of developing new businesses with a low probability of success if utilize more effective innovation activities in developing new business in enterprises or organizations throughout this study.

• Animal Bioscience
• /
• v.34 no.12
• /
• pp.1886-1894
• /
• 2021

Objective: Growth hormone (GH) and insulin-like growth factor I (IGF-I) play a critical role in animal growth rates. We aimed to investigate the effect of GH and IGF-I genotypes on body weight (BW), dominance, and gene expression in slow-growing chickens at different ages. Methods: A total of 613 Korat chickens (KRs) were bred and divided into three groups by genotype - A1A1, A1A3, and A3A3 for GH and AA, AC, and CC for IGF-I. Chickens were weighed every two weeks, and liver and breast muscle tissues were collected at 10 weeks of age. Genetic parameters of KRs were estimated using ASReml software. The GH and IGF-I mRNA levels were measured by quantitative polymerase chain reaction. Significant differences between traits were analyzed using the generalized linear model. Results: A significant effect of GH genotypes on BW was found at most ages, and the A1A1 genotype had the highest value of BW. Compared with the A3A3 genotype, the A1A1 and A1A3 genotypes showed a higher dominance effect at 0 and 2 weeks, and genotype A1A1 had the highest value of dominance at 8 weeks of age. A difference in GH mRNA levels between genotypes was detected in breast muscle at 6 weeks and in the liver tissue at 2 weeks. In the case of IGF-I gene, the AA genotype had the highest BW at the beginning of life. Significant differences in BW dominance were found at 2 weeks. However, IGF-I mRNA levels were not different among genotypes in both breast muscles and liver tissues. Conclusion: Our results revealed that GH and IGF-I influence growth, but may not be involved in heterosis. GH can be used as a marker gene in selection programs for growth because the homozygous genotype (A1A1) had the highest BW at all ages. The IGF-I is not a useful marker gene for selection programs.

• Proceedings of the IEEK Conference
• /
• 2002.07b
• /
• pp.1137-1140
• /
• 2002

A V-band low-noise amplifiers (LNA) based on the Millimeter-wave monolithic integrated circuit (MIMIC) technology were fabricated using high performance 0.1 $\mu\textrm{m}$ $\Gamma$-shaped pseudomorphic high electron mobility transistors (PHEMT＇s), coplanar waveguide (CPW) structures and the integrated process for passive and active devices. The low-noise designs resulted in a two-stage MIMIC LNA with a high S$\sub$21/ gain of 14.9 dB and a good matching at 60 ㎓. 20 dBm of IP3 and 3.9 dB of minimum noise figure were also obtained from the LNA. The 2-stage LNA was designed in a chip size of 2.3 ${\times}$1.4 mm$^2$by using 70 $\mu\textrm{m}$ ${\times}$2 PHEMT’s. These results demonstrate that a good low-noise performance and simultaneously with a high gain performance is achievable with GaAs PHEMT's in the 60 ㎓ band.

• Proceedings of the IEEK Conference
• /
• 2000.06b
• /
• pp.84-87
• /
• 2000

In this paper, a high gain-broad bandwidth MMIC distributed amplifier was designed using cascaded single section distributed amplifier configuration. The PHEMT for this studies was fabricated at our lab The PHEMT has a 0.2 $\mu\textrm{m}$ gate length. a 80 $\mu\textrm{m}$ unit gate width and 4 gate fingers. A designed MMIC amplifier have higher S$\sub$21/ gain than the common distributed amplifier using the same number of active devices. From the simulated result, we obtained that the S$\sub$21/ gain of DC ∼ 20 GHz bandwidth was 15.6 dB and flatness was ${\pm}$0.9 dB, and input and output reflection coefficient were lower than -8 dB. The simulated gain shows an improvement 7.3 dB compared with those of conventional distributed amplifier. And the chip size is 2.0 ${\times}$ 1.2 $\textrm{mm}^2$.

• The Journal of Society for e-Business Studies
• /
• v.16 no.3
• /
• pp.169-190
• /
• 2011

The growth rates of manufacturer M, the domestic market leader in the infant formula and dairy industry, has slowed because of the market reduction which is caused by the falling birth rates, the increasing growth in import of foreign~made infant formula and fierce competition with other rivals in domestic market. In this situation, they find a way to make new opportunities of service innovation by using 'Open Collaboration Innovation Methodology(OCIM)'. As s result, they can provide their customers with the differentiated service which is created by collaborating with the external partners, exchanging the value each other and connecting the accumulated internal capabilities to the external resources. This study focused on the application of the Open Collaboration Innovation Methodology which is used to the manufacturer M's servicitization. Also it is described in the direction of forth study based on the limits that occurred when the M company use the methodology and the matters that have to be considered when other companies apply the methodology.

• Proceedings of the IEEK Conference
• /
• 2000.07b
• /
• pp.1009-1012
• /
• 2000

In this paper, we have designed and fabricated power PHEMT’s with an unit gate width of 80$\mu\textrm{m}$ and 4 fingers, and MIMIC power amplifiers using the PHEMT’s as well. The PHEMT’s have a 0.2$\mu\textrm{m}$ gate length and source to drain spacing of 3$\mu\textrm{m}$. The characteristics of the fabricated PHEMT’s are 4.08dB of S$\sub$21/ gain at the 35GHz and 317mS/mm of gm, and 62GHz of f$\sub$T/ and 120GHz of f$\sub$max/. The designed and fabricated MIMIC’s power amplifiers with 6 PHEMT’s and MIN capacitors were fully passivated by 1000 Α of Si$_3$N$_4$ film for higher performance and surface protects. The chips were processed using the MINT processes, and size was 3.25 ${\times}$ 1.8$\textrm{mm}^2$. The fabricated MIMIC power amplifiers have RF characteristics such as 11.25dB of S$\sub$21/ gain, 11.37dB of input return-loss and 12.69dB of output return-loss at the 34.55GHz.

• International Journal of Computer Science & Network Security
• /
• v.21 no.8
• /
• pp.327-341
• /
• 2021

The knowledge management was considered as the inevitable result of the rule of knowledge in this era, and its importance became clear in being the main source for achieving success, the need to consider and manage knowledge as an independent field that must be addressed with a clear scientific methodology has become intangible - they are very valuable and a strategic asset. On the other hand, the innovation process relates to all parts of the organization, and helps to improve the behavioral patterns of individuals and their attitudes towards adopting modern and innovative ideas, it is a purposeful process adopted by the senior management and works to provide the capabilities and requirements for embodying the innovative behavior in it. In the field of dealing with the market, it is a product of the organization's innovative approach, which aims at advancement, change, and intended and organized renewal. The main objective of this article is to determine the most appropriate ways to integrate knowledge management mechanisms to employ innovation factors within universities based on the role of universities in supporting innovation. This was achieved through reviewing many relevant research and listing the most prominent concepts of knowledge management, its importance, objectives, and processes determining the stages of knowledge management application, the requirements for applying knowledge management, and the obstacles that impede its application; Then the statement "Innovation in universities, through which it addressed the concept of innovation, its importance, stages, and requirements for its application, as well as identifying the most prominent models of innovation, and obstacles to innovation, in addition to that the role of universities in supporting innovation will be identified. From the surveyed study done in this article, we concluded that the relationship among organizational culture, knowledge management and innovation capability can provide useful insights for managers regarding developing a strong culture, promote knowledge management practices effectively and eventually enhance the whole organization's innovation capability. Also, we found that different components of Knowledge Management as Knowledge activities, Knowledge types, transformation of knowledge and technology have a significant positive effect in bringing innovation through transformation of knowledge into knowledge assets in universities.