• Journal of the Korean Magnetic Resonance Society
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• v.22 no.4
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• pp.149-157
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• 2018

Diabetes is known to be one of common causes for several types of peripheral nerve damage. Diabetic neuropathy (DN) is a significant complication lowering the quality of life that can be frequently found in diabetes patients. In this study, the metabolomic characteristic of DN and Diabetes was investigated with NMR spectroscopy. The sera samples were collected from DN patients, Diabetes patients, and healthy volunteers. Based on the pair-wise comparison, three metabolites were found to be noticeable: glucose, obviously, was upregulated both in DN patients (DNP) and Diabetes. Citrate is also increased in both diseases. However, the dietary nutrient and biosynthesized metabolite from glucose, ascorbate, was elevated only in DNP, compared to healthy control. The multivariate model of OPLS-DA clearly showed the group separation between healthy control-DNP and healthy control-Diabetes. The most significant metabolites that contributed the group separation included glucose, citrate, ascorbate, and lactate. Lactate did not show the statistical significance of change in t-test while it tends to down-regulated both in DNP and Diabetes. We also conducted the ROC curve analysis to make a multivariate model for discrimination of healthy control and diseases with the identified three metabolites. As a result, the discrimination model between healthy control and DNP (or Diabetes) was successful while the model between DNP and Diabetes was not satisfactory for discrimination. In addition, multiple combinations of lactate and citrate in the OPLS-DA model of healthy control and diabetes group (DNP + Diabetes patients) gave good ROC value of 0.952, which imply these two metabolites could be used for diagnosis of Diabetes without glucose information.

• Journal of the Korea Institute of Building Construction
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• v.6 no.1 s.19
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• pp.87-91
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• 2006

Since water leakage and cracks are not the source of serious problems such as long-term lowering of performance and durability of a stricture, including damages to operating facilities of a structure, damages to internal finishing materials, exhibition, and goods, and pollution of residential environment, they might have led to development of positive coping skills; however, an instant loss of lives or property due to earthquake, explosion, typhoon, or a fire was indeed neglected. In these days, repair materials for leakage cannot help but being taken in temporary way without any noticeable countermeasure. This kind of repair is socially criticized many times that is defective construction even if this costs a lot. It was not arrange the standard for construction methods of sealer of injection type for leakage maintenance, even it has been used various type of construction methods for leakage part. In conclusion, we suggest that the construction methods of sealer of injection type for leakage maintenance for leakage to establish the leakage repairing technology as increase of structure demand. Therefore, it would be possible to provide a stage-by-stage solution by developing systematic research activities among the industry, schools, and research institutes to spread maintenance management techniques globally through technical solution to water leakage and cracks, acquisition of structural safety with prolonged durability for life cycle, reduction of water leakage repair expense s, and so on.

• Journal of the Ergonomics Society of Korea
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• v.25 no.3
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• pp.25-32
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• 2006

As national income increases, consumers began to place a great deal of weight on products or quality of their life. They would like to have products which are more convenient to use and could meet their emotional desire in addition to its basic functional requirements. An automobile is one of the transportation system for human beings and the factor such as safety or environmentaly-friendly is regarded as important things resulting from it's popularization. In fact, domestic design technology leaves much to be desired compared with excellent manufacturing techniques. For this reason, some problems, like lowering of usage, could be caused by introducing technological data as it is from overseas. A survey of domestic car users has found that the most preferred condition (step height) is 460~495cm when they get in and out of their car. Men use their visual information and then get in the car, taking motion fit for each condition when automobile condition is changed. In other words, men get in cars actively within the range of conditions used for this study. These results were found from a motion study, when getting in a car, and checking the possibility of getting injury in accordance with the change of condition as well.

• Journal of Appropriate Technology
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• v.5 no.1
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• pp.46-53
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• 2019

It should be supported by the ease and economic production in terms of appropriate technology to be widely used in the real applying fields. In particular, the diagnosis of diseases is one of the most difficult areas to apply to the developing countries compared to other fields because of the high costs of professional manpower, equipment, and medial reagents. In recent years, paper, which is one of the most common materials around, has been used to fabricate the disease diagnostic chips, particularly without any special facilities or the equipment. These new technologies lead the possibility of using point-of-care testing devices that can be manufactured quickly in the field by lowering the production cost. These paperbased technologies will contribute to solve many of the deadliest medical problems in developing countries and ultimately improve the quality of human life.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.20 no.3
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• pp.65-72
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• 2020

The Internet of Things(IoT) is to build a hyper-connected society through interconnection, and on this basis, to improve the quality of life and productivity, including solving social problems, and to become the next growth engine for the nation. The open common eco-system pursued by the IoT can start with the under- standing of the word 'open'. The IoT can achieve the expected effect of lowering the barriers to entry of technology development, and in these changes, OSSW and OSHW play a very important role in accelerating IoT eco-system maturity and breaking the boundaries between industries to promote convergence. Recently, it has developed into an intelligent IoT that combines artificial intelligence (AI) with the connectivity of the IoT. Here, I will analyze the direction of development of the IoT through understanding and analysis of open source.

• Journal of the Korean Regional Science Association
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• v.36 no.1
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• pp.3-16
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• 2020

Most of the Korean apartment complexes are considered as gated communities having characteristics such as self-sufficiency in service provision, self-governance and exclusiveness. Today the exclusionary features of apartment complexes are reinforced by a new practice of erecting gates against pedestrians in addition to the existing walls without considering implication of the practice over neighborhoods. Three groups of residents, those who live in low-rise residential areas without walls, apartment complexes with walls and apartment complexes with walls and gates were surveyed to measure the impact of the new exclusionary practice of gated communities on social sustainability of neighborhoods. Gates turn out to improve social sustainability indicators related to life quality but lower social cohesion of neighborhoods by lowering inclusiveness indicator considerably. The new apartment complexes with increased exclusiveness shake the established order of co-existence between low-rise residential areas and apartment complexes and strengthen spatial and social segregation within neighborhoods.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.11B
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• pp.1651-1658
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• 2010

As indicators of life quality have recently shown great improvement, early stage medical examination and health care patterns are usually preformed before diseases occur. Thus, hand acupuncture, as an alternative medicine to reflect these movements of preventative work and health care, is widely used these days. Therefore, in this paper, we measured the change of voice signals elements associated with heart by stimulating the heart A16 acupuncture point, and then we investigated possible improvements of cardiac function through analysis of cross-comparisons between measurements of cardiac changes. With this in mind, we collected voice samples associated with heart before and after stimulating the corresponding A16 acupuncture point, and we performed an experiment by applying the second formant bandwidth and Jitter. As result, stimulating the A16 acupuncture point results to lowering the second formant bandwidth and Jitter. The result has proven that using voice signal processing technology can help improvement of heart function.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.8
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• pp.4713-4716
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• 2014

Several methods that have been used to manage a degasing process in recent years, such as an injection method that uses aluminum molten metal powder and chemicals, and the input method that supplies argon and nitrogen, or chlorine gas using a gas blow-tube. On the other hand, these methods have some problems, and it is a difficult process to handle pollution due to the production of considerable toxic gases, such as chlorine and fluoride gas, irregular effects, and lowering work efficiency due to the excessive processing time. The problems that are most fatal are the production of considerable sludge due to a reaction of aluminum molten metal with chemicals, loss of metals, and the decreasing life of refractory materials. To solve these problems, this study developed a technology that is related to continuous casting of molten aluminum metal and monolithic degasing apparatus.

• Korean Journal of Agricultural Science
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• v.41 no.4
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• pp.415-424
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• 2014

This study was carried out to determine the effect of storage condition, such as temperature or relative humidity (RH) in home-style refrigerator, on the change of quality traits and storage characteristics of Hanwoo M. longissimus to find out the condition for prolongation of shelf-life with maintaining the meat quality for consumers. Samples were sliced in $1{\pm}0.2cm$ thickness, and packed in foamed polystyrene tray with linear low-density polyethylene (LLD-PE) film to simulate the pre-packed Hanwoo loin sold in retail market, then stored in home-style refrigerator ($5^{\circ}C$/17% RH, Control), and chambers of $5^{\circ}C$/55% RH (T1), $5^{\circ}C$/85% RH (T2), and $-1^{\circ}C$/99% RH (T3), respectively. Quality traits (color, pH, water holding capacity, shear force and grilling loss) and storage characteristics (thiobarbituric acid reactive substances, volatile basic nitrogen and total microbes) were measured at 1, 4, 7, 14 and 21 days after storage. Lightness of Hanwoo loin stored in T1, T2 and T3 were higher than that of control until 14 days of storage, however at the end of storage (21 days) control showed significantly higher than other treatments (p<0.05). Redness and Yellowness of Hanwoo loin samples stored in T1 and T3 were significantly higher than others during all storage period (p<0.05). The water holding capacity (WHC) of control was significantly higher than others until 14 days of storage (p<0.05), however, Hanwoo loin stored in T2 was the highest ($63.64{\pm}7.62kg/cm^2$) at 21 days of storage. Hanwoo loin stored in T1 showed significantly lower shear force than others during all storage period (p<0.05). There was no consistent tendency in pH and grilling loss during storage in all treatments. Hanwoo loin stored in T1 showed lower TBARS value than others during storage period, however there was a rapid increase to $0.34{\pm}0.27mg$ malonaldehyde/kg meat at 21 days of storage. And, all the treated samples (from T1 to T3) showed significantly lower VBN values at 21 days of storage (p<0.05). The population of total aerobic microbes were significantly increased in all treatments as storage period increasing, and the population of T3 ($2.28{\pm}0.57logCFU/g$) was the lowest at 21 days of storage (p<0.05). From those results, it could be predicted the better storage condition to maintain the meat quality and prolong the shelf-life of Hanwoo loin by lowering the temperature and adjusting the humidity about 55%.

• Journal of Chest Surgery
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• v.39 no.12 s.269
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• pp.920-926
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• 2006

Background: Mortality and morbidity of anastomotic complications after esophagectomy have gradually decreased in recent years. However, swallowing difficulties and reflux symptoms after esophagogastrostomy continue to be a burden jeopardizing the quality of life. In the present study, we evaluated the quality of esophagogastrostomy by analyzing anastomotic stenosis and reflux esophagitis. Material and Method: A retrospective analysis was made in 74 patients who underwent esophagogastrostomy after esophagectomy by one surgeon between January 1995 and December 2004. 53 patients of them received endoscopic examination during follow-up($29{\pm}23.6$ months, range $5{\sim}111$ months). Reflux esophagitis and stenosis at anastomostic site were analyzed according to the techniques and locations of esophagogastrostomy. Result: The median age at the time of repair was $60.3{\pm}8.87$ years(range $39{\sim}81$ years). 23 patients received a hand-sewn esophagogastric anastomosis and 30 patients a circular stapled one. There was no significant statistical difference in terms of anastomotic stenosis(p=0.64) and reflux esophagitis(p=0.41) between the two groups. Cervical anastomosis was peformed in 26 patients and intrathoracic anastomosis in 27 patients. No significant statistical difference in anastomotic stenosis between the two groups was found(p=0.44), but reflux esophagitis was noted in 3 patients in the cervical anastomosis group and 14 patients in the intrathoracic anastomosis group(p=0.003). Conclusion: Cervical anastomosis was supposed to have a better quality of esophagogastrostomy by lowering the risk of reflux esophagitis. In the future, the comprehensive study including a patient's subjective symptom and Barrett's metaplasia should be performed in larger cases.