• Title/Summary/Keyword: Lower Detection Limit

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Performance Characteristics of In-Situ Particle Monitors at Sub-Atmospheric Pressure (감압상태에서의 In-Situ Particle Monitor의 성능특성)

  • Bae, Gwi-Nam
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.22 no.11
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    • pp.1564-1570
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    • 1998
  • In-situ particle monitors(ISPMs) are widely used for monitoring contaminant particles in vacuum-based semiconductor manufacturing equipment. In the present research, the performance of a Particle Measuring Systems(PMS) Vaculaz-2 ISPM at subatmospheric pressures has been studied. We created uniform upstream conditions of particle concentration and measured the detection efficiency, the lower detection limit, and the size response of the ISPM using uniform sized methylene blue aerosol particles. The effect of particle size, particle velocity, particle concentration, and system pressure on the detection efficiency was examined. Results show that the detection efficiency of the ISPM decreases with decreasing chamber pressure, and with increasing mass flow rate. The lower detection limit of the ISPM, determined at 50 % of the measured maximum detection efficiency, was found to be about $0.15{\sim}0.2{\mu}m$, which is similar to the minimum detectable size of $0.17{\mu}$ given by the manufacturer.

Concentration Distribution of Polychlorinated Biphenyls(PCBs) in Urban Watershed (도심하천유역의 PCBs 농도 분포)

  • Kim, Hyun-Seung;Kim, Il-Kyu
    • Journal of Korean Society of Water and Wastewater
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    • v.26 no.6
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    • pp.757-766
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    • 2012
  • In this study, we have examined concentration distribution and patterns of PCBs in waters, sediments and soils in an agricultural area of South Korea to investigate the relationship between PCBs sources and concentration levels. The concentration of PCBs in water samples were ranged from lower values below detection limit to 8.25 ug/L and the concentration of PCBs in sediment samples were ranged from lower values below detection limit to 76.67 ug/Kg. The concentration of PCBs in soil samples were ranged from lower values below detection limit to 23.51 ug/Kg. These contamination levels were far below the guideline values suggested for environmental quality assessment. The homologue patterns in samples varied from sample to sample, but isomer patterns were very similar with each other. PCB-138 and PCB-153 were predominant congeners in the soil and sediment, which were similar to the results obtained from previous studies. With these results, the assessment of potential sources of PCBs contamination in the sediments of the Nakdong river basin was performed. The principal components were extracted by Principal Component Analysis(PCA). As the result of PCA, it could be expected that PCBs in samples of this study were more affected by PCB products than combustion processes and mostly affected by already-known sources. The PCBs in the soil and sediment samples were related with commercial PCB products.

Evaluation of Autochemical Analyzer Toshiba 120 FR (자동화학 분석기 Toshiba 120 FR의 평가)

  • Park, Jum Gi
    • Korean Journal of Clinical Laboratory Science
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    • v.36 no.2
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    • pp.98-109
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    • 2004
  • The lower limit of detection, precision, setting method of target value, reportable range determination, recovery, linearity, and comparison study with another equipment was evaluated for the Toshiba-120FR chemistry autoanalyzer which was newly introduced at the Daejeon Veteran Hospital in Dec. 2003. Nineteen kinds of test for AST, ALT, ALP, LDH, GGT, TP, ALB, GLU, T-cho, T-bil, TG, UA, CAL, IP, AMY, HDL-C, LDL-C, Cre and BUN were performed to evaluate the lower limit of detection, precision, setting method of target value, reportable range determination, recovery, linearity, and comparison study with other equipment according to the NCCLS guidelines(EP5-A, EP6-P, EP9-A). The Toshiba-120FR autochemical analyzer showed good precision for all tested items. The data concerning the lower limit of detection, precision(total CV 0.47%~3.65%), setting method of target value, reportable range determination, recovery(93%~111%), linearity($R^2=0.997{\sim}0.999$), and comparison study(r=0.977~0.999) with other equipment was acceptable for all tested items. The results of evaluation for the Toshiba-120FR autochemical analyzer showed that this equipment could be used as an alternative to other equipment.

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Determination of Minimum Detectable Activity in Environmental Samples (환경방사능 측정에서의 검출한계치의 정량적 고찰 및 최소검출방사능 농도 계산)

  • Lee, Myung-Ho;Shin, Hyun-Sang;Hong, Kwang-Hee;Cho, Young-Hyun;Lee, Chang-Woo
    • Journal of Radiation Protection and Research
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    • v.24 no.3
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    • pp.171-184
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    • 1999
  • In this paper, using statistical theory the basic concepts and the formulars of lower limit of detection were deasribed. Assuming that risks of 5% are acceptable (95% confidence level), lower limits of detection were calculated on the measuring apparatus for alpha, beta and gamma nuclides. Also, on the basis concepts of lower limit of detection, the MDA values were calculated for the radionuclides detected easily in the environment. These results make it possible to evaluate confidence limits on the radioanalytical results in the environmental sample.

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Laser-induced Graphene Based Wearable Glucose Patch Sensor with Ultra-low Detection Limit (레이저 유도 그래핀 기반의 고성능 웨어러블 포도당 패치센서)

  • Nah, Joongsan;Yoon, Hyosang;Xuan, Xing;Kim, Jiyoung;Park, Jaeyeong
    • Journal of Sensor Science and Technology
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    • v.28 no.1
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    • pp.47-51
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    • 2019
  • Sweat-based glucose sensors are being widely investigated and researched as they facilitate painless and continuous measurement. However, because the concentration of sweat glucose is almost a hundred times lower than that of blood glucose, it is important to develop electrochemical sensing electrode materials that are highly sensitive to glucose molecules for the detection of low concentrations of glucose. The preparation of a flexible and ultra-sensitive sensor for detection of sweat glucose is presented in this study. Oxygen and nitrogen are removed from the surface of a polyimide film by exposure to a CO2 laser; hence, laser-induced graphene (LIG) is formed. The fabricated LIG electrode showed favorable properties of high roughness and good stability, flexibility, and conductivity. After the laser scanning, Pt nanoparticles (PtNP) with good catalytic behavior were electrodeposited and the glucose sensor thus developed, with a LIG/PtNP hybrid electrode, exhibited a high order of sensitivity and detection limit for sweat glucose.

Chemiluminescence immunochromatographic analysis for the quantitative determination of algal toxins

  • Pyo, Dongjin;Kim, Taehoon
    • ALGAE
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    • v.28 no.3
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    • pp.289-296
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    • 2013
  • For the quantitative detection of algal toxin, microcystin, a chemiluminescence immunochromatographic assay method was developed. The developed system consists of four parts, chemiluminescence assay strip (nitrocellulose membrane), horse radish peroxidase labeled microcystin monoclonal antibodies, chemiluminescence substrate (luminol and hydrogen peroxide), and luminometer. The performance of the chemiluminescence immunochromatographic assay system was compared with high performance liquid chromatography (HPLC) detection. The detection limit of chemiluminescence immunochromatographic assay system is several orders of magnitude lower than with HPLC. The chemiluminescence immunochromatography and HPLC results correlated very well with the correlation coefficient ($r^2$) of 0.979.

Detection and non-propagating cracks of small fatigue crack (미소피로균열의 검출과 정류균열)

  • 이종형
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.14 no.3
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    • pp.603-609
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    • 1990
  • Detection and non-propagating cracks of small fatigue crack for smooth and pre-cracked specimens were examined in a carbon steel. The fretting oxide induced crack closure triggered by the roughness induced crack closure has an important role in determing the length. The fatigue limit for the with no cracks or with a short pre-crack is lower at R=-1 than that at R=0. A non-propagating crack are quite different between points near the specimen's surface and those of deepest penetration.

Real-time malfunction detection of plasma etching process using EPD signal traces (EPD 신호궤적을 이용한 플라즈마 식각공정의 실시간 이상검출)

  • Cha, Sang-Yeob;Yi, Seok-Ju;Koh, Taek-Beom;Woo, Kwang-Bang
    • Journal of Institute of Control, Robotics and Systems
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    • v.4 no.2
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    • pp.246-255
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    • 1998
  • This paper presents a novel method for real-time malfunction detection of plasma etching process using EPD signal traces. First, many reference EPD signal traces are collected using monochromator and data acquisition system in normal etching processes. Critical points are defined by applying differentiation and zero-crossing method to the collected reference signal traces. Critical parameters such as intensity, slope, time, peak, overshoot, etc., determined by critical points, and frame attributes transformed signal-to symbol of reference signal traces are saved. Also, UCL(Upper Control Limit) and LCL(Lower Control Limit) are obtained by mean and standard deviation of critical parameters. Then, test EPD signal traces are collected in the actual processes, and frame attributes and critical parameters are obtained using the above mentioned method. Process malfunctions are detected in real-time by applying SPC(Statistical Process Control) method to critical parameters. the Real-time malfunction detection method presented in this paper was applied to actual processes and the results indicated that it was proved to be able to supplement disadvantages of existing quality control check inspecting or testing random-selected devices and detect process malfunctions correctly in real-time.

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Novel Detection Technology for Glycated Hemoglobin using Gold Nanoparticles (금 나노입자를 이용한 새로운 당화혈색소의 검출 기술)

  • Lee, Soo Suk
    • Journal of Sensor Science and Technology
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    • v.25 no.6
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    • pp.435-439
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    • 2016
  • We report a novel detection technology for glycated hemoglobin (HbA1c) that is measured primarily to identify the three-month average plasma glucose concentration. In enzymatic measuring of glycated hemoglobin, the generated hydrogen peroxide was then used as a reducing agent of gold (III) for the synthesis of gold (0). Gold nanoparticles obtained from this novel approach were measured by optical and piezoelectric methods. In optical method, we have developed polymer based film-type sensor cartridge filled with all the reagents for glycated hemoglobin analysis and the cartridge worked very well having the detection limit of 0.53% of glycated hemoglobin. On the other hand, quartz crystal microbalance (QCM) sensors also have been developed to determine the abilities of surface modified QCM sensors at various levels of the concentration of glycated hemoglobin to bind gold nanoparticles and limit of detection was 0.90%. Finally, despite of relatively lower sensitivities of QCM sensor and film-type optical sensor than well-plate based optical detection, these two sensors were available to measure the glycated hemoglobin level for diabetes patients and normal person.

Low complexity hybrid layered tabu-likelihood ascent search for large MIMO detection with perfect and estimated channel state information

  • Sourav Chakraborty;Nirmalendu Bikas Sinha;Monojit Mitra
    • ETRI Journal
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    • v.45 no.3
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    • pp.418-432
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    • 2023
  • In this work, we proposed a low-complexity hybrid layered tabu-likelihood ascent search (LTLAS) algorithm for large multiple-input multiple-output (MIMO) system. The conventional layered tabu search (LTS) approach involves many partial reactive tabu searches (RTSs), and each RTS requires an initialization and searching phase. In the proposed algorithm, we restricted the upper limit of the number of RTS operations. Once RTS operations exceed the limit, RTS will be replaced by low-complexity likelihood ascent search (LAS) operations. The block-based detection approach is considered to maintain a higher signal-to-noise ratio (SNR) detection performance. An efficient precomputation technique is derived, which can suppress redundant computations. The simulation results show that the bit error rate (BER) performance of the proposed detection method is close to the conventional LTS method. The complexity analysis shows that the proposed method has significantly lower computational complexity than conventional methods. Also, the proposed method can reduce almost 50% of real operations to achieve a BER of 10-3.