• 제목/요약/키워드: Low and Intermediate-Level

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Separate and Joint Associations of Shift Work and Sleep Quality with Lipids

  • Charles, Luenda E.;Gu, Ja K.;Tinney-Zara, Cathy A.;Fekedulegn, Desta;Ma, Claudia C.;Baughman, Penelope;Hartley, Tara A.;Andrew, Michael E.;Violanti, John M.;Burchfiel, Cecil M.
    • Safety and Health at Work
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    • 제7권2호
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    • pp.111-119
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    • 2016
  • Background: Shift work and/or sleep quality may affect health. We investigated whether shift work and sleep quality, separately and jointly, were associated with abnormal levels of triglycerides, total cholesterol (TC), and low-and high-density lipoprotein cholesterol in 360 police officers (27.5% women). Methods: Triglycerides, TC, and high-density lipoprotein were analyzed on the Abbott Architect; low-density lipoprotein was calculated. Shift work was assessed using City of Buffalo payroll work history records. Sleep quality (good, ${\leq}5$; intermediate, 6-8; poor, ${\geq}9$) was assessed using the Pittsburgh Sleep Quality Index questionnaire. A shift work + sleep quality variable was created: day plus good sleep; day plus poor sleep; afternoon/night plus good; and poor sleep quality. Mean values of lipid biomarkers were compared across categories of the exposures using analysis of variance/analysis of covariance. Results: Shift work was not significantly associated with lipids. However, as sleep quality worsened, mean levels of triglycerides and TC gradually increased but only among female officers (age- and race-adjusted p = 0.013 and 0.030, respectively). Age significantly modified the association between sleep quality and TC. Among officers ${\geq}40$ years old, those reporting poor sleep quality had a significantly higher mean level of TC ($202.9{\pm}3.7mg/dL$) compared with those reporting good sleep quality ($190.6{\pm}4.0mg/dL$) (gender- and race-adjusted p = 0.010). Female officers who worked the day shift and also reported good sleep quality had the lowest mean level of TC compared with women in the other three categories (p = 0.014). Conclusion: Sleep quality and its combined influence with shift work may play a role in the alteration of some lipid measures.

Effect of Dietary Fiber Level on the Performance and Carcass Traits of Mong Cai, F1 Crossbred (Mong Cai×Yorkshire) and Landrace×Yorkshire Pigs

  • Len, Ninh Thi;Lindberg, Jan Erik;Ogle, Brian
    • Asian-Australasian Journal of Animal Sciences
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    • 제21권2호
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    • pp.245-251
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    • 2008
  • The effects of feeding diets containing 20% (L) or 30% (H) neutral detergent fiber (NDF) (DM basis) on performance and carcass traits were studied in three breeds of pig, including pure Mong Cai (MC), crossbred Landrace$\times$Yorkshire (LY) and crossbred MC$\times$Yorkshire (F1). The experiment had a factorial design with two factors, breed and diet. Eighteen piglets of each breed ($60{\pm}3days$) were randomly allocated to three treatments: L-L, low fiber diet in both growing and finishing periods; L-H, low and high fiber diet in the growing and finishing period, respectively; and H-H, high fiber diet in both periods. The diets were iso-energetic and iso-nitrogenous within feeding period. The main fibrous ingredients of the diets were rice bran and cassava residue. There were no effects of fiber level on daily dry matter feed intake (DMI), expressed as g/kg metabolic body weight (BW0.75), in both feeding periods (p>0.05). DMI was highest for MC, followed by F1 and LY (p<0.001). Average daily gain (ADG) in L-L and L-H was higher than in H-H in the growing period (p<0.001) and overall (p<0.05), while feed conversion ratio (FCR) was higher in H-H than in L-L and L-H in the growing period (p<0.05) and overall, but no significant differences between treatments were found in the finishing period. In both periods, Landrace$\times$Yorkshire had the highest ADG and the lowest FCR, followed by F1 and Mong Cai (p<0.001). There were no interactions between breed and diet for performance and carcass traits. Carcass and dressing percentage was lower for L-H and H-H than for L-L (p<0.05). There were no significant differences among treatments in back fat thickness and lean meat percentage, or in crude protein and ether extract contents of lean meat. Carcass, dressing and lean meat percentage was highest for LY, lowest for MC and intermediate for F1 (p<0.001). It can be concluded that feeding a high fiber diet in the growing period reduced pig performance, but there was no effect in the finishing period. Pure Mong Cai pigs are not particularly suitable for meat purposes, although the F1 cross with Large White had reasonably good growth performance and carcass quality.

전략적(戰略的) 기술경쟁(技術競爭)과 산업(産業)·무역정책(貿易政策) (Effects of Trade and Industrial Policies in the Presence of Strategic Technology Competition)

  • 이홍구
    • KDI Journal of Economic Policy
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    • 제14권3호
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    • pp.3-21
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    • 1992
  • 기술경쟁과 생산경쟁에 범위(範圍)의 경제(經濟)가 존재하고, 두 기업이 생산경쟁에서 전략적(戰略的) 대체관계(代替關係)에 있는 경우 경쟁기업간의 기술경쟁(技術競爭)은 적극적인 양상을 띠게 된다. 생산단계의 경쟁자를 견제하기 위환 전략적 대응으로 기술경쟁단계(技術競爭段階)에서 과잉된 기술투자(技術投資)와 기술이전(技術移轉)이 유발되는 것이다. 또한 과잉된 기술경쟁은 제품가격(製品價格)의 급속한 하락(下落)으로 연결된다. 이와 같은 맥락에서 최근 보도 된 바 있는 국산화 신제품에 대한 외국기업의 저가공세(低價攻勢)는 과점적(寡占的) 시장(市場)에서 나타나는 자연스런 현상으로 이해할 수 있다. 또한 기술경쟁단계에서 기술개발투자(技術開發投資)와 기술이전(技術移轉)은 전략적(戰略的) 대체관계(代替關係)뿐만 아니라 전략적(戰略的) 보완관계(補完關係)를 가질 수 있다. 이와 같이 대조적인 전략적 대응관계가 가능하기 때문에 국산화(國産化) 노력(努力)을 견제하고 국내시장(國內市場) 점유율(占有率)을 유지하기 위해 저가공세를 취하는 외국기업에 대한 대응방안(對應方案)으로 검토되고 있는 수입품에 대한 조정관세(調整關稅), 국산화 신제품에 대한 수요창출(需要創出), 기술투자의 채산성 보장을 위한 보조금지급(補助金支給) 등과 같은 정책변수(政策變數) 활용(活用)이 바람직한가를 사전적으로 규정하기는 어렵다. 즉 전략적 무역(산업)정책이론에서 주장하는 것처럼 관세부과(關稅賦課)나 보조금지급(補助金支給)이 국내기업의 시장점유율(市場占有率)과 기술투자규모(技術投資規模)를 향상 증대시키는 것은 아니라는 것이다.

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변형률에 따른 모래-고무 혼합재의 거동 특성: 실험적 관찰 (Characteristics of Sand-Rubber Mixtures under Different Strain Levels: Experimental Observation)

  • 이창호;변용훈;이종섭
    • 한국지반공학회논문집
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    • 제27권3호
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    • pp.85-94
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    • 2011
  • 다양한 모래부피비($sf=V_{sand}/V_{total}$)를 가지는 시료를 조성하여 변형률 크기에 따른 모래-고무 혼합재($D_{sand}/D_{rubber}=1$)의 거동을 분석하였다. 공진주시험, 압밀시험, 그리고 직접전단시험을 실시하였다. 변형률 크기에 따라 모래와 고무는 혼합재 전체 거동을 서로 다르게 제어한다. $sf{\geq}0.4$의 혼합재는 비선형 전단강성의 감소가 관찰되는 반면, $sf{\leq}0.2$의 낮은 모래부피비를 가지는 혼합재는 상당히 높은 탄성한계변형률을 보인다. 고무 입자가 force chain의 역할을 수행할 때 수직변형은 급격한 증가를 보인다. 혼합재 내의 고무부피비가 감소함에 따라 혼합재의 강도는 증가하는 경향을 보이며 $sf{\leq}0.8$의 혼합재는 전단변형에 따라 부피 수축 거동을 보인다. 고무 입자는 변형률 크기에 따라 혼합재 내에서 서로 다른 역할을 수행한다: 미소변형률 영역에서는 혼합재 내의 접촉수 증가 및 소성의 제어; 중간변형률 영역에서는 force chain의 좌굴 방지; 그리고 대변형률 영역에서는 혼합재의 부피수축 거동을 이끈다.

Gramoxone이 단백질 level에 따라 흰쥐 간에 미치는 독성에 관한 연구 (Effect of Dietary Protein Levels on the Manifestation of Gramoxone Toxicity in Rat Liver)

  • Kim, Sung-Ro;Lee, Hyun-Ki;Jo, Un-Bock;Park, Byung-Tae
    • 한국식품영양과학회지
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    • 제21권3호
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    • pp.231-240
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    • 1992
  • 식이속의 단백질농도가 피리딘계 제초제인 gramoxone의 독성발현에 어떤 영향을 미치는가를 알기 위해 Wistar계 흰쥐 수놈 36마리 (6~7주령)를 6개의 실험사료군으로 나누어 2주간 사육하며 그 미치는 영향을 조사하였다. 체중증가 상황은 각단백-gramoxone군들의 경우 각 정상단백군에 비해 저조하였으며 저단백-gramoxone군에서 제일 심하였고 고단백-gramoxone군에서는 유의한 차가 없었다. 간의 지질함량변화는 각단백-gramoxone군들의 경우, 고단백-gramoxone군을 제외하고 각 단백군에 비해 증가하는 경향을 나타내었으며 특히 저단백-gramoxone군에서 가장 심하였다. 간장내 TBA가는 정상단백군, 저단백군, 고단백군 및 고단백-gramoxone군 사이에는 유의차가 없었으나 정상단백-gramoxone군과 저단백-gramoxone군의 경우 전자의 실험군들에 비해 매우 높았다. 정상단백군 및 고단백군의 간에서는 유의한 형태적인 변화가 없었으나 저단백군과 각단백-gramoxone군들에서는 정도의 차이는 이었으나 간조직의 변화가 나타났으며 간세포 지방변화 및 Kupffer 세포의 숫적인 증가가 관찰되었다. 특히 간세포 지방변화는 저단백-gramoxone군에서 심하였고 고단백-gramoxone군에서는 현저하지않았다. 간세포의 glycogen함량은 각단백-gramoxone군들에서 타군들에 비해 증가하는 경향을 보였으며 저단백-gramoxone군에서 제일 심하였다. 제일심하였다.

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Cyberknife Dosimetric Planning Using a Dose-Limiting Shell Method for Brain Metastases

  • Yoon, Kyoung Jun;Cho, Byungchul;Kwak, Jung Won;Lee, Doheui;Kwon, Do Hoon;Ahn, Seung Do;Lee, Sang-Wook;Kim, Chang Jin;Roh, Sung Woo;Cho, Young Hyun
    • Journal of Korean Neurosurgical Society
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    • 제61권6호
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    • pp.753-760
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    • 2018
  • Objective : We investigated the effect of optimization in dose-limiting shell method on the dosimetric quality of CyberKnife (CK) plans in treating brain metastases (BMs). Methods : We selected 19 BMs previously treated using CK between 2014 and 2015. The original CK plans ($CK_{original}$) had been produced using 1 to 3 dose-limiting shells : one at the prescription isodose level (PIDL) for dose conformity and the others at low-isodose levels (10-30% of prescription dose) for dose spillage. In each case, a modified CK plan ($CK_{modified}$) was generated using 5 dose-limiting shells : one at the PIDL, another at intermediate isodose level (50% of prescription dose) for steeper dose fall-off, and the others at low-isodose levels, with an optimized shell-dilation size based on our experience. A Gamma Knife (GK) plan was also produced using the original contour set. Thus, three data sets of dosimetric parameters were generated and compared. Results : There were no differences in the conformity indices among the $CK_{original}$, $CK_{modified}$, and GK plans (mean 1.22, 1.18, and 1.24, respectively; p=0.079) and tumor coverage (mean 99.5%, 99.5%, and 99.4%, respectively; p=0.177), whereas the $CK_{modified}$ plans produced significantly smaller normal tissue volumes receiving 50% of prescription dose than those produced by the $CK_{original}$ plans (p<0.001), with no statistical differences in those volumes compared with GK plans (p=0.345). Conclusion : These results indicate that significantly steeper dose fall-off is able to be achieved in the CK system by optimizing the shell function while maintaining high conformity of dose to tumor.

Major Element Changes in the Upper Quaternary Sediment of the East Sea (Sea of Japan): Their Implications for the Onset of Holocene

  • Hyun, Sang-Min;Han, Sang-Joon;Bahk, Jang-Jun
    • Journal of the korean society of oceanography
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    • 제33권4호
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    • pp.185-195
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    • 1998
  • Two piston cores (94PC-2 and 95PC-4) taken from the East Sea (Sea of Japan) are studied to evaluate the paleoceanographic changes and its interaction with climatic variation. The bulk geochemistry of the non-biogenic fractions of 54 sediment samples is determined using X-ray fluorescence. Four geochemical stratigraphic units at both core sediments are recognized based on the variations in major element concentration. These chemical stratigraphic units correspond well with the sedimentological and paleontological facies. Source materials are considered as basic and/or intermediate rocks judging from silica content. A distinctive boundary around 11 kyr may correspond to Younger Dryas event. The switch of most major elements at this level and the distinctive changes in concentration of typical terrigenous elements (TiO$_2$ and Al$_2$O$_3$) are the strong evidence for the difference in sources of terrigenous materials. The weathering indices exhibit high degree in Core 94PC-2 and low degree in Core 95PC-4. The changes in weathering degree can be distinguished by the lowest value occurred at 11 kyr in Core 94PC-2 and by a gradual decrease from top to bottom in Core 95PC-4. The profiles of potassium and sodium exhibit specific excursions between the Holocene and the late Pleistocene. This implies that sediments of the two cores originating from different sources with different weathering degrees. The distinct two-group distributions in K$_2$O/CaO vs. Na$_2$O/K$_2$O also support the difference in provenance of aluminosilicate materials at the boundary of 11 kyr. Thus, supply patterns of terrigenous materials are stable in Holocene and more complicated in the last glacial period.

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Elevational Distribution of Breeding Bird Communities in Seoraksan National Park, Korea

  • Hwang, Hyun-Su;Lee, Jae-Kang;Eom, Tae-Kyung;Bae, Ho-Kyoung;Lee, Dong-Ho;Lim, Jong-Hwan;Jung, Sung-Cheol;Park, Chan-Ryul;Rhim, Shin-Jae
    • 한국산림과학회지
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    • 제109권1호
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    • pp.109-114
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    • 2020
  • In this study, the elevational distribution of breeding birds in Seoraksan National Park, Korea was investigated. Forty-six species of birds were documented from line transect surveys taken from Seorakdong at 230 m above sea level (a.s.l.) to the Daechungbong summit at 1708 m asl. Birdspecies richness and diversity were highest in Seorakdong and lowest at the Daechungbong summit. As elevation increased, bird species richness and diversity decreased, with a humped-shape trend being observed between 700 m and 1200 m a.s.l. Stepwise analyses revealed that breeding bird species diversity indices were significantly negatively correlated with elevation (r2 = 0.327, P < 0.001) and positively correlated with vegetational coverage (r2 = 0.324, P = 0.046). Higher elevations supported fewer birds than low and intermediate elevations. Projections at the local scale, including data on behavior and habitat use by birds, will be necessary for optimal conservation and management of the bird communities in Seoraksan National Park.

Radiotoxicity flux and concentration as complementary safety indicators for the safety assessment of a rock-cavern type LILW repository

  • Jo, Yongheum;Han, Sol-Chan;Ok, Soon-Il;Choi, Seonggyu;Yun, Jong-Il
    • Nuclear Engineering and Technology
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    • 제50권8호
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    • pp.1324-1329
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    • 2018
  • This study presents a practical application of complementary safety indicators, which can be applied in a safety assessment of a radioactive waste repository by excluding a biosphere simulation and comparing the artificial radiation originating from the repository with the background natural radiation. Complementary safety indicators (radiotoxicity flux from geosphere and radiotoxicity concentration in seawater) were applied in the safety assessment of a rock-cavern type low and intermediate level radioactive waste (LILW) repository in the Republic of Korea. The natural radionuclide ($^{40}K$, $^{226,228}Ra$, $^{232}Th$, and $^{234,235,238}U$) concentrations in the groundwater and seawater at the Gyeongju LILW repository site were measured. Based on the analyzed concentrations of natural radionuclides, the levels of natural radiation were determined to be $8.6{\times}10^{-5}$ - $8.0{\times}10^{-4}Sv/m^2/yr$ and $6.95{\times}10^{-5}Sv/m^3$ for radiotoxicity flux from the geosphere and radiotoxicity concentration in seawater, respectively. From simulation results obtained using a Goldsim-based safety assessment model, it was determined that the radiotoxicity of radionuclides released from the repository is lower than that of the natural radionuclides inherently present in the natural waters. The applicability of the complementary safety indicators to the safety case was discussed with regard to reduction of the uncertainty associated with biosphere simulations, and communication with the public.

A micro-computed tomographic study using a novel test model to assess the filling ability and volumetric changes of bioceramic root repair materials

  • Fernanda Ferrari Esteves Torres;Jader Camilo Pinto;Gabriella Oliveira Figueira;Juliane Maria Guerreiro-Tanomaru;Mario Tanomaru-Filho
    • Restorative Dentistry and Endodontics
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    • 제46권1호
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    • pp.2.1-2.8
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    • 2021
  • Objectives: New premixed bioceramic root repair materials require moisture for setting. Using micro-computed tomography (micro-CT), this study evaluated the filling ability and volumetric changes of calcium silicate-based repair materials (mineral trioxide aggregate repair high-plasticity [MTA HP] and Bio-C Repair, Angelus), in comparison with a zinc oxide and eugenol-based material (intermediate restorative material [IRM]; Dentsply DeTrey). Materials and Methods: Gypsum models with cavities 3 mm deep and 1 mm in diameter were manufactured and scanned using micro-CT (SkyScan 1272. Bruker). The cavities were filled with the cements and scanned again to evaluate their filling capacity. Another scan was performed after immersing the samples in distilled water for 7 days to assess the volumetric changes of the cements. The statistical significance of differences in the data was evaluated using analysis of variance and the Tukey test with a 5% significance level. Results: Bio-C Repair had a greater filling ability than MTA HP (p < 0.05). IRM was similar to Bio-C and MTA HP (p > 0.05). MTA HP presented the largest volumetric change (p < 0.05), showing more volume loss than Bio-C and IRM, which were similar (p > 0.05). Conclusions: Bio-C Repair is a new endodontic material with excellent filling capacity and low volumetric change. The gypsum model proposed for evaluating filling ability and volumetric changes by micro-CT had appropriate and reproducible results. This model may enhance the physicochemical evaluation of premixed bioceramic materials, which need moisture for setting.