• 제목/요약/키워드: Loss of Life

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Aging of hair follicle stem cells and their niches

  • Hansaem Jang;Yemin Jo;Jung Hyun Lee;Sekyu Choi
    • BMB Reports
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    • 제56권1호
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    • pp.2-9
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    • 2023
  • Hair follicles in the skin undergo cyclic rounds of regeneration, degeneration, and rest throughout life. Stem cells residing in hair follicles play a pivotal role in maintaining tissue homeostasis and hair growth cycles. Research on hair follicle aging and age-related hair loss has demonstrated that a decline in hair follicle stem cell (HFSC) activity with aging can decrease the regeneration capacity of hair follicles. This review summarizes our understanding of how age-associated HFSC intrinsic and extrinsic mechanisms can induce HFSC aging and hair loss. In addition, we discuss approaches developed to attenuate ageassociated changes in HFSCs and their niches, thereby promoting hair regrowth.

Loss of gene function and evolution of human phenotypes

  • Oh, Hye Ji;Choi, Dongjin;Goh, Chul Jun;Hahn, Yoonsoo
    • BMB Reports
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    • 제48권7호
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    • pp.373-379
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    • 2015
  • Humans have acquired many distinct evolutionary traits after the human-chimpanzee divergence. These phenotypes have resulted from genetic changes that occurred in the human genome and were retained by natural selection. Comparative primate genome analyses reveal that loss-of-function mutations are common in the human genome. Some of these gene inactivation events were revealed to be associated with the emergence of advantageous phenotypes and were therefore positively selected and fixed in modern humans (the "less-ismore" hypothesis). Representative cases of human gene inactivation and their functional implications are presented in this review. Functional studies of additional inactive genes will provide insight into the molecular mechanisms underlying acquisition of various human-specific traits. [BMB Reports 2015; 48(7): 373-379]

Making Sense of Loss and Belongingness: Korean Transracial Adoptees' Journey from Europe to Korea

  • Favre, Beatrice;Park, Hye Jun
    • Child Studies in Asia-Pacific Contexts
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    • 제6권1호
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    • pp.1-16
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    • 2016
  • From 1953 to 2015, approximately 200,000 children born in Korea were adopted into foreign countries. Many studies have focused on Korean adoptees growing up in the US, as the majority of these children were adopted by American families. In comparison, research on Korean transracial adoptees raised in European countries is limited. Thus, the current study aims to highlight the journey of Korean transracial adoptees from Europe to Korea. Three participants narrated their life stories as adoptees in two separate interview sessions. The findings of this study call attention to the adoptees' ongoing reconsideration of their identity as they assimilate life experiences within two disparate cultural settings in Europe and Korea. The study found that ambiguous loss faced by the adoptees from their childhood in Europe continued to their adulthood in Korea. Major themes of the participants' narratives in their journey from Europe to Korea focused on their feelings of loss and the lack of belongingness. This study found that the sense of loss and the lack of belongingness changed over time. Participants were active agents in the process of their journey from Europe to Korea, as they constantly worked to adapt to and improve their situation in face of adversity.

공급률 및 탈곡통 길이 변화에 따른 자탈형 콤바인 탈곡 성능 (Threshing Performance dependent upon Feed Rate and Threshing Drum Length for Head-Feed Combine)

  • 서신원;이상우;허윤근
    • 농업과학연구
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    • 제33권2호
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    • pp.159-166
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    • 2006
  • Threshing loss was increased due to dropping of the threshing efficiency when the 4 row head-feed combine harvested 5 row rice to improve harvesting performance of a combine. Reasonable design criteria were examined to determine the ranges of both of feed rate and the length of threshing drum for the 4 row head-feed combine being used as a 5-row combine. Harvesting performance increased as working width or working speed increased, it resulted in 15% increase when the working width increased from 4 row to 5 row. Harvesting operations of the 4 row combine performed normally in the 4 row rice in threshing loss less than 1%, however, threshing loss increased to 2.25% in the 5 row due to poor threshing efficiency. The length of threshing drum was increased from 710 mm to 810 mm as well as the speed of crop feed chain was increased from 0.61 m/s to 0.75 m/s so as to improve the poor threshing efficiency resulted from the enlarged working width from the 4 row to the 5 row, which would decrease threshing loss less than 1%.

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Effects of Different Restoration Practices on Nutrient Loss from Sediments after a Forest Fire in Two Watersheds

  • Hwang, Tae-Hwan;Lee, Kyu-Song;Park, Sang-Deog;Choung, Yeon-Sook
    • Journal of Ecology and Environment
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    • 제30권3호
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    • pp.265-269
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    • 2007
  • The loss of nitrogen and phosphorus from sediments in two watersheds, one naturally regenerating and one artificially planted, in Sacheon-myun, Gangneung-si, Gangwon Province, were measured two years after a forest fire in 2000. Sediment losses occurred five times in the course of the year. In the artificially planted watershed, $50{\sim}140$ times more nitrogen and $54{\sim}139$ times more phosphorus were lost with sediments during heavy rains, from July to August, than in the naturally regenerating watershed. When the typhoon Rusa struck the country, 1,389 times more nitrogen and 1,647 times more phosphorus were lost from the artificial watershed. In spite of the limited scope of this study, these results suggest that artificially planted watersheds are extremely vulnerable to catastrophic natural disasters such as typhoons. Elevated loss of nutrients in the artificially planted watershed might have resulted from the mechanized silvicultural practices employed immediately after the fire. To maximize soil preservation, the timing and necessity of plantation practices should be reconsidered, and rapidly regenerating vegetation should be protected to promote nutrient uptake and to mitigate nutrient loss from burned forests.

농촌거주 노인의 죽음불안이 삶의 질에 미치는 영향 -자아통합감의 매개효과를 중심으로- (The Effects of Death Anxiety on Quality of Life in Rural Elderly -Focusing on the Mediating Effects of Self-Integration-)

  • 남희수;진봉희;이정임
    • 농촌지도와개발
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    • 제29권2호
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    • pp.81-98
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    • 2022
  • The purpose of this study is to examine the mediating effect of a sense of self-integration in the relationship between death anxiety and death anxiety on the quality of life for the elderly living in rural areas. First, death anxiety among the elderly living in rural areas was found to have a negative effect on the quality of life, and among the sub-elements of death anxiety, the anxiety of loss of existence and the anxiety of the death process were negative on the quality of life. Second, it was found that there is a positive effect on the sense of self-integration, which is a parameter such as anxiety about loss of existence, anxiety about the death process, and anxiety about post-mortem outcomes. Third, it was confirmed that the sense of self-integration mediates between death anxiety and quality of life. Based on the results of this study, several discussions and suggestions were made to improve the quality of life of the elderly living in rural areas by improving the sense of self-integration and reducing death anxiety.

고령자의 상실감과 자아통합감의 관계 (The Relationship between the Grief of Loss and the Sense of Ego-Integrity of the elderly)

  • 김후경 ;이순철 ;오주석
    • 한국심리학회지 : 문화 및 사회문제
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    • 제13권2호
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    • pp.17-32
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    • 2007
  • 상실이란 일반적으로 개인이 가장 의미 있다고 생각하는 물건, 사람, 소유 혹은 생각을 박탈 당하는 것으로 일생에 있어 불가피한 경험이며, 특히 고령자의 특성상 이와 같은 경험에 노출될 가능성이 높다. 상실로 인한 부정적 정서, 즉 상실감은 자연스럽고 정상적인 것이지만, 이를 원활히 극복하지 못하는 경우 심리·사회적인 부적응을 겪을 수 있다. 따라서 본 연구에서는 고령자의 상실감이 어떤 요소들로 구성이 되어있는지 알아보고, 이것이 고령자의 자아통합감에 어떤 영향을 미치는지 알아보고자 하였다. 만 65세 이상의 고령자 97명을 대상으로 자료를 수집하여 분석한 결과, 상실감의 요인은 '경제적 상실', '사별 상실', '건강 상실', '관계의 상실'로 구분되었으며 이들 요인들이 전체적으로 '죽음에 대한 수용'을 제외한 나머지 자아통합감의 요인들과 부적인 상관을 보였다. 특히 '경제적 상실'로 인한 상실감은 '죽음에 대한 수용'과 '노령에 대한 수용'을 제외한 나머지 자아통합감 하위요인들에 부적인 영향을 미치고 있었으며, '건강 상실'과 '관계의 상실'도 각각 '노령에 대한 수용' 및 과거부터 현재까지를 포함하는 생에 대한 태도 및 만족도에 부적인 영향을 미치는 것으로 나타났다. 한편, 고령자 상실감 척도의 '사별 상실' 요인과 자아통합감의 '죽음에 대한 수용' 요인은 모든 분석단계에서 통계적으로 유의한 결과를 보이지 않았다.

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중학교 레슬링 선수의 단기간 체중 감량이 신체 구성과 적혈구 Heinz body 형성에 미치는 영향 (Effects of Rapid Weight Loss on Body Composition and Heinz Body Formation in Middle-School Wrestlers)

  • 김종오;김영욱;윤진환
    • 생명과학회지
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    • 제16권6호
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    • pp.884-889
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    • 2006
  • 본 연구는 중학교 레슬링 선수의 단기간 체중 감량이 신체구성 성분과 적혈구의 산화적 손상에 어떠한 영향을 미치는가를 알아보고자 실시되었다. 중학교 레슬링 선수의 시합 전 단기간 체중 감량 법에 의한 체중 감량은 주로 탈수에 의해 이루어지는 것임을 확인하였으며, 인체 내 산소운반 능력을 가진 적혈구의 산화적 손상 지표로 이용되는 RDW, ESR, 그리고 Heinz body 형성의 변화를 확인해 본 결과 성장기에 있는 중학교 레슬링 선수의 시합 전 단기간 체중 감량법에 의한 체중감량은 적혈구의 산화적 손상을 증가시켜 인체 내 산소운반 능력을 감소시킬 가능성이 있음을 확인하였다. 추후 좀 더 다양한 감량법과 더불어 기전적인 연구가 필요할 것으로 생각한다.

Effect of Packaging Method on the Quality of Strawberry, Tomato, and plum during Storage

  • Lee, Se-Hee;Lee, Myung-Suk;Lee, Yong-Woo;Sun, Nam-Kyu;Song, Kyung-Bin
    • 한국식품저장유통학회:학술대회논문집
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    • 한국식품저장유통학회 2003년도 제23차 추계총회 및 국제학술심포지움
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    • pp.187-187
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    • 2003
  • To examine the effect of packaging method on strawberry, tomato, and plum quality, the rate of weight loss, Hunter a value, decay rate, anthocyanin contents, and microbial (total bacterial counts, mold and yeast, and pseudomonas) changes were determined during storage. Strawberry was packaged with low density polyethylene (LDPE). Tomato and plum were packaged with high density polyethylene film (HDPE). Strawberries, tomatoes, and plums were then stored at 4$^{\circ}C$ and 20$^{\circ}C$, respectively. LDPE package was the most effective on the decrease of decay rate of strawberry and the rate of weight loss for packaged strawberry was lower than that of the non-packaged. HDPE package was the most effective on the rate of weight loss during storage of tomatoes and plums regardless of storage temperature. Hunter a value increased during storage. Anthocyanin contents of plums increased overall with increasing storage time, and plums stored without package were changed more than those with package. Microbial changes of strawberry, tomato, and plum stored at 4$^{\circ}C$ and 20$^{\circ}C$ were monitored during storage. Packaging method did not affect the microbial change, yet temperature did affect the microbial change significantly. These results indicate that storage of these commodities at 4$^{\circ}C$ should be recommended in terms ,of microbial safety as well as quality and shelf-life.

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