• 약학회지
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• 제45권6호
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• pp.591-598
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• 2001

The photochemical study of Viscum album (Loranthaceae) led to the isolation of twelve compounds, lupeol (1), betulonic acid (2), betulinic acid (3), terminic acid (4), ursolic acid (5), $\beta$-sitosterol (6), $\alpha$- spinasterol (7), oleanolic acid (8) , 5-hydroxy-1- (4′-hydoxyphenyl) -7- (4"-hydroxyphenyl) -hepta-1- en-3-on (9), 2′-hydroxy -4′, 6′- dimethoxychalcone -4-O-glycoside (10) ,2′-hydroxy-4′, 6′-dimethoxychalcone -4-O- [apiosal(1longrightarrow12)]glucoside (11) and syringin (12). Their structures were established by chemical and spectroscopic methods. The cytotoxicity of the isolated compounds was evaluated by sulforhodamine B assay against five cultured human tumor cell lines.

• 대한약침학회지
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• 제18권1호
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• pp.7-18
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• 2015

Objectives: Loranthus ferrugineus (L. ferrugineus) from Loranthaceae, a mistletoe, is a medicinal herb used for a variety of human ailments. Traditionally, decoctions of this parasitic shrub have been mainly used to treat high blood pressure (BP) and gastrointestinal complaints; usage which is supported by experimental based pharmacological investigations. Nonetheless, there is still limited data available evaluating this plant's traditions, and few studies have been scientifically translated toward evidence based phytomedicine. We therefore provide a concise review of the currently available L. ferrugineus literature and discuss potential directions for future areas of investigation. Methods: We surveyed available literature covering ethnopharmacological usage of L. ferrugineus and discussed relevant findings, including important future directions and shortcomings for the medicinal values of this parasitic shrub. Results: Evidence based pharmacological approaches significantly covered the medicinal application of L. ferrugineus for hypertension and gastrointestinal complaint management, with a particular focus on the active hydrophilic extract of this herb. Conclusion: Understanding the sites of action of this plant and its beneficial effects will provide justification for its use in old traditional treatments, and potentially lead to the development of therapies. Other medicinal applicative areas of this parasitic shrub, such as wound healing, gerontological effects, and antiviral and anticancer activities, are yet to be researched.

• 생약학회지
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• 제35권2호통권137호
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• pp.134-138
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• 2004

A bioassay-guided fractionation of the whole extract of Viscum album var. coloratum Ohwi (Loranthaceae) led to the isolation of two triterpenoidal components; oleanolic acid (1) and ${\beta}-amyrin$ acetate (2), and a flavonoid, homoflavoyadorinin B (3) as well as large quantity of free fatty acid mixtures as active ingredients of the extract responsible for the antitumoral property. The EtOAc soluble fraction and BuOH soluble fraction of the extract demonstrated a significant inhibition on the proliferation of cultured human tumor cells such as A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nerve system), and HCT-15 (colon) in vitro, whereas the remaining water soluble fraction exhibited a poor inhibition. The intensive phytochemical investigation of the EtOAc soluble fraction and BuOH soluble fraction of the extract indicated that the oleanolic acid (1) and large amounts of free fatty acid mixtures might be attributed to the in vitro antitumoral property of the whole extract of Viscum album var. coloratum.

• 생약학회지
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• 제43권4호
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• pp.297-301
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• 2012

In the course of screening for antioxidant compounds by measuring the radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH), a total extract of the twigs of Taxillus delavayi (Loranthaceae) was found to show potent radical scavenging activity. Subsequent activity-guided fractionation of the methanolic extract led to the isolation of two phenolic compounds, catechin (1) and galloyl catechin (2), as active principles. Their structures were elucidated by spectroscopic studies. These two compounds showed the significant antioxidative effects on DPPH, and riboflavin- and xanthin-originated superoxide quenching activities. And these two compounds also showed strong nitric oxide radical scavenging effects. In riboflavin- and xanthin-originated superoxide quenching activities and nitric oxide radical scavenging effect, compound 2 showed better antioxidant activities than vitamin C.

• 식물분류학회지
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• 제46권4호
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• pp.348-355
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• 2016

2015-2016년 사이 라오스 식물상을 조사하는 과정에서 발견한 미기록 현화식물을 보고한다. 라오스 푸카오쿠오아이 국가생물다양성보전지구에서 야목단과(Melastomataceae)의 Phyllagathis tuberosa (C. Hansen) Cellinese & S. S. Renner와 꼬리겨우살이과(Loranthaceae)의 Tolypanthus pustulatus Barlow를 발견하였으며, 이들은 태국의 기준표본 채집지 외에는 아직까지 채집된 바 없는 종들로, 라오스에 분포하는 것을 처음으로 확인하였다. 한편, 인동과(Caprifoliaceae)의 Lonicera bournei Hemsl.는 20세기초 라오스에 분포하는 것으로 보고된 바 있으나 이후 채집 기록이 없다가, 라오스 시앙쾅주 포사보국가보호지구에서 다시 발견하였다. 본 연구의 결과는 라오스 및 동남아시아 국가의 식물상 및 그 특성을 규명하는 데 도움이 될 것으로 기대된다.

• Biomolecules & Therapeutics
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• 제11권1호
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• pp.1-4
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• 2003

Plants are known as important source in the search for new drugs. The twelve compounds from Viscum album (Loranthaceae), lupeol (1), betulonic acid (2), betulinic acid (3), terminic acid (4), ursolic acid (5), $\beta$-sitosterol (6), $\alpha$-spinasterol (7), oleanolic acid (8), 5-hydroxy-1-(4′-hydoxyphenyl)-7-(4"-hydroxyphenyl)-hepta-1-en-3-on (9), 2′-hydroxy-4′,6′-dimethoxychalcone-4-O-glucoside (10), 2′-hydroxy-4′,6′-dimethoxychalcone-4-O-[apiosyl(l$\longrightarrow$2)]glucoside (11) and syringin (12) were evaluated for their immunomodulatory properties. Compounds 6 and 11 induced the macrophage tumoricidal activity and the lymphocyte blastogenesis. In addition, these compounds stimulated the macrophages to induce the production of TNF-$\alpha$ and NO. These findings suggest that compounds 6 and 11 are modulating various elements of the host immune response.

• Journal of Plant Biology
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• 제35권2호
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• pp.173-182
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• 1992

The parasitic flowering plants obtain nutrients and water from their host plants through a parasitic organ, haustorium, which connects both structurally and physiologically host and parasite. The parasitism in angiosperms thus can be understood from the knowledge of the haustorial structure. The haustoria have evolve convergently and independently in several unrelated taxa; therefore, they have similar morphology. Many anatomical studies on the haustoria in several parasites in the pst have been carried out by light microscopy. Ultrastructural studies on the haustoria, which are started from the end of 1060s', have provided new information relating to the phenomenon of parasitism in angiosperms. The purpose of this paper is to introduce and compare the structure of haustoria between parasitic plants. The results may help an understanding of phylogenetic relationships of parasitic angiosperms. The haustoria of some families, such as Santalaceae, Orobancaceae, Scrophulariaceae, Loranthaceae (or Viscaceae), and Convolvulaceae (Cuscuta) will be discussed.

• 식물분류학회지
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• 제51권3호
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• pp.305-318
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• 2021

We report 14 species of flowering plants as new additions to the flora of Laos. These are Illex viridis (Aquifoliaceae), Capparis erycibe (Capparaceae), Euphorbia bokorensis (Euphorbiaceae), Exacum darae (Gentianaceae), Aeschynanthus cambodiensis (Gesneriaceae), Tetraphyllum roseum (Gesneriaceae), Utricularia gibba (Lentibulariaceae), Macrosolen brandisianus (Loranthaceae), Decaschistia siamensis (Malvaceae), Nyssa yunnanensis (Nyssaceae), Adenia penangiana var. penangiana (Passifloraceae), Pentaphylax euryoides (Pentaphylacaceae), Wikstroemia bokorensis (Thymelaeaceae), and Debregeasia wallichiana (Urticaceae). We discovered the species during a botanical survey of the Phou Khao Khouay National Biodiversity Conservation Area (PKKNBCA) of Lao PDR in 2015-2019. In addition, nine rarely collected flowering plant species in Laos are newly reported for the PKKNBCA.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.202.2-202.2
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• 2003

A bioassay-guided fractionation of the whole extract of Viscum album (a parasitic plant : Loranthaceae) led to the isolation of two triterpenoidal components, oleanolic acid (1), ${\beta}$-amyrin acetate (2), homoflavoyadorinin B (3) as well as large quantity of free fatty acid mixtures as active ingredients of the extract responsible for the antitumoral property. The EtOAc soluble part and BuOH soluble part of the extract demonstrated a significant inhibition on the proliferation of cultured human tumor cells such as A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nerve system) and HCT-15 (colon) in vitro, whereas the remaining water soluble part exhibited a poor inhibition. (omitted)

• 한국산림과학회지
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• 제102권3호
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• pp.428-436
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• 2013

우리나라 희귀식물인 꼬리겨우살이(꼬리겨우살이과) 자생 집단의 효율적인 보전대책을 수립하기 위하여 자생 집단의 분포와 자생지 특성을 구명하고, 이를 토대로 보전지위 평가를 수행하였다. 한반도에서 꼬리겨우살이는 지리산에서부터 백두대간을 따라 설악산까지 분포하였으며, 전체 개체 중 97.8%가 강원도 지역에 집중분포 하였다. 그리고 꼬리겨우살이의 1,385개체가 480개의 기주식물에 기생하는 것으로 확인되었으며, 해발 353~1,250 m의 범위에서 광이 충분한 능선부위에 분포하는 것으로 관찰되었다. 꼬리겨우살이의 기주식물 범위는 5과 6속 10분류군(9종 1변종)이었으며, 그중 신갈나무에서 81.5%가 확인되어 가장 선호하는 결과를 보였다. 꼬리겨우살이의 분포와 자생지 특성조사 결과를 토대로 IUCN 적색목록 기준에 의한 보전지위를 평가한 결과 지역수준에서 VU등급으로 분류되었다. 그리고 꼬리겨우살이의 최대 분포지역인 설악산과 태기산, 오대산 지역에 대해 현지 내 보전구역으로 설정하여 집중보호를 해야 할 것으로 판단되었다. 이와 같이 꼬리겨우살이의 자생 집단의 지속가능한 보존을 위한 보전전략과 이를 위한 전략수립을 도출하였다.