• Title/Summary/Keyword: Longitudinal study

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Effects of Horse Bone Powder Extract on Longitudinal Bone Growth in Adolescent Male Rats (마골(馬骨) 추출물의 성장기 흰쥐 장골 길이 성장에 대한 효과)

  • Lee, Se-Na;Choi, Han;Son, Jae-Bong;Jeong, Jae-Seung;Kim, Yun-Jung;Kang, Dae-Pyung;Park, Soo-Yeong;Kang, Se-Chan;Leem, Kang-Hyun
    • The Korea Journal of Herbology
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    • v.24 no.3
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    • pp.69-77
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    • 2009
  • Objectives : This study was designed to investigate the effects of horse bone powder extract on the growth of longitudinal bone in adolescent male rats. Methods: Longitudinal bone growth was measured by fluorescent microscopy. To examine the effects on the growth plate metabolism, the total height of growth plate, the induction of local insulin-like growth factor-1 (IGF-1), and bone morphogenetic protein-2 (BMP-2) were measured. Results: Horse bone powder extract enhanced longitudinal bone growth and total height of the growth plate. Also, it promoted the induction of local IGF-1 and BMP-2 of the growth plate. Conclusions: This study shows that the horse bone powder extract effects longitudinal bone growth in adolescent rats and might be used for both stunted adolescents and inherent growth failure patients.

Effects of Cheunggyeongsamul-tang Extract on Longitudinal Bone Growth in Adolescent Female Rats (청경사물탕(淸經四物湯) 추출물의 성장기 흰쥐 장골길이 성장에 대한 효과)

  • Lee, Jung-Hun;Lee, Se-Na;Son, Jae-Bong;Keum, So-Hyun;Leem, Kang-Hyun
    • The Korea Journal of Herbology
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    • v.24 no.4
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    • pp.149-157
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    • 2009
  • Objectives : This study was designed to investigate the effects of Cheunggyeongsamul-tang extract on the growth of longitudinal bone in adolescent female rats. Methods : Longitudinal bone growth was measured by fluorescent microscopy. To examine the effects on the growth plate metabolism, the total height of growth plate, the induction of local insulin-like growth factor-1 (IGF-1), IGF-1 receptor, bone morphogenetic protein-2 (BMP-2), BMPR-1A, indian hedgehog (IHH), and parathyroid hormone-related protein (PTH-rP) were measured. Results : Cheunggyeongsamul-tang extract enhanced longitudinal bone growth and total height of the growth plate. Also, it promoted the induction of local IGF-1, BMP-2, IHH and PTH-rP of the growth plate. Conclusions : This study shows that the Cheunggyeongsamul-tang extract effects longitudinal bone growth in adolescent rats and might be used for both stunted adolescents and inherent growth failure patients.

Confounding of Time Trend with Dropout Process in Longitudinal Data Analysis

  • Kim, Ji-Hyun;Choi, Hye-Hyun
    • Communications for Statistical Applications and Methods
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    • v.9 no.3
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    • pp.703-713
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    • 2002
  • In longitudinal studies, outcomes are repeatedly measured over time for each subject. It is common to have missing values or dropouts for longitudinal data. In this study time trend in longitudinal data with dropouts is of concern. The confounding of time trend with dropout process is investigated through simulation studies. Some simulation results are reported for binary responses as well as continuous responses with patterns of dropouts varying. It has been found that time trend is not confounded with random dropout process for binary responses when it is estimated using GEE.

Effective Stiffness of Circular Reinforced Bridge Columns (철근콘크리트 원형단면 교각의 유효강성)

  • 배성용;김준범;이재훈
    • Proceedings of the Korea Concrete Institute Conference
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    • 2001.05a
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    • pp.833-838
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    • 2001
  • The objectives of this study are to investigate effective stiffness of circular reinforced bridge columns and to provide reasonable effective stiffness equations for seismic design to the current Korean Bridge Design Standard. The material nonlinear analysis was conducted for 5184 columns of which variables were the concrete compressive stress, the steel yielding stress, the longitudinal steel location parameter, the longitudinal steel ratio, the axial load level, and the diameter of section. The current Korean Bridge Design Standard generally used the gross section stiffness because of unclear provision, it may be non-conservative because of being evaluated greater design seismic force and less design displacement than those of the abroad provision. Therefore, the proposed effective stiffness equations include three variables such as : the longitudinal steel location parameter, the longitudinal steel ratio, and the axial load ratio. Two equations of effective stiffness are proposed which may be used for earthquake force estimation and for earthquake displacement estimation, respectively.

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Impregnation of Castanea creanata Wood by Hydrophobic Oil

  • Ahmed, Sheikh Ali;Lee, Kyoung-Min;Chun, Su-Kyoung
    • Journal of the Korea Furniture Society
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    • v.19 no.1
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    • pp.91-96
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    • 2008
  • This paper investigates the penetration of essential oil into radial and longitudinal directions of Castanea crenata. Present study was performed to know the essential oil penetration depth in radial and longitudinal direction of Castanea crenata. Essential oil penetration depth was found higher in longitudinal direction than in radial direction and it was about 53 times high at 15.0 second of penetration. In early wood, fiber conducted oil more than that of large vessel. In heartwood, fiber had played an important role for the conduction of oil. But in sapwood, small vessel conducted oil deeper than wood fiber, which was also significantly different from large. On the other hand, large vessel in heartwood had statistically lower penetration depth than that of fiber and small vessel. At the beginning of penetration the speed was high and gradually decreased in course of time.

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Multivariate analysis of longitudinal surveys for population median

  • Priyanka, Kumari;Mittal, Richa
    • Communications for Statistical Applications and Methods
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    • v.24 no.3
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    • pp.255-269
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    • 2017
  • This article explores the analysis of longitudinal surveys in which same units are investigated on several occasions. Multivariate exponential ratio type estimator has been proposed for the estimation of the finite population median at the current occasion in two occasion longitudinal surveys. Information on several additional auxiliary variables, which are stable over time and readily available on both the occasions, has been utilized. Properties of the proposed multivariate estimator, including the optimum replacement strategy, are presented. The proposed multivariate estimator is compared with the sample median estimator when there is no matching from a previous occasion and with the exponential ratio type estimator in successive sampling when information is available on only one additional auxiliary variable. The merits of the proposed estimator are justified by empirical interpretations and validated by a simulation study with the help of some natural populations.

Alcohol Permeability in Castanea crenata Sieb. et Zucc

  • Lee, Kyoung-Min;Ahmed, Sheikh Ali;Chun, Su-Kyoung
    • Journal of the Korea Furniture Society
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    • v.18 no.4
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    • pp.312-316
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    • 2007
  • A study was conducted to know 99.5% ethyl alcohol penetration depth in radial and longitudinal direction of Castanea crenata. Alcohol penetration depth was found higher in longitudinal direction by about 12.47 times. In both earlywood and latewood, fiber conducted alcohol in higher depth than that of large and small vessel. Penetration depth of alcohol after 15.0 second of penetration in longitudinal direction, there was no significant difference among fiber in sapwood and heartwood, and vessel in sapwood. At the beginning of penetration the speed was high and then gradually decreased.

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Study on the Generation of Machining Program for Large Screws Defined by Longitudinal-Section Profile (축 평형단면의 형상정의에 의한 대형 스크류 가공프로그램 생성에 관한 연구)

  • 이원규;이민환;안중환
    • Journal of the Korean Society for Precision Engineering
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    • v.17 no.6
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    • pp.83-88
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    • 2000
  • In machining large screws such as those of extruders, it takes long time to machine them on conventional machines which usually use single-tipped fixed tools. And it is also difficult to use an existing CAD/CAM coftware when trying to get over the problems of conventional machines and making use of CNC machines. In this paper, generation of machining program using rotational tools for large screws defined by longitudinal-section profile is descrebed. Use of rotational tools in machining plays an important role in saving machining time. In the sort of extruder screws, it is easy to define a screw shape by longitudinal-section profile, and by which improvement of dimensional accuracy can be expected. The CAM software developed in this paper is based on user's and designer's friendliness.

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A Study on Stress Wave Propagation by Finite Element Analysis (유한요소법에 의한 2차원 응력파 전파 해석에 관한 연구)

  • 황갑운;조규종
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.18 no.12
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    • pp.3369-3376
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    • 1994
  • A finite element program for elastic stress wave propagation is developed in order to investigate the shape of stress field and analysis the magnitude of stress wave intensity at time increment. Accuracy and reliance of the finite element analysis are acquired when the element size is smaller than the product of the stress wave speed and the critical value of increasing time step. In the finite element analysis and theoretical solution, the longitudinal stress wave is propagated to the similar direction of impact load, and the stress wave intensity is expressed in terms of the ratio of propagated area. The direction of shear wave is declined at an angle of 45 degrees compared with longitudinal stress wave and the speed of shear wave is half of the longitudinal stress wave.

Study on active vibration control based on wave viewpoint using the longitudinal wave separation method (종파 분리 방법을 이용한 파동 관점의 능동 진동 제어)

  • Jung, Byung-Bo;Park, Young-Jin;Park, Youn-Sik
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2007.05a
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    • pp.928-933
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    • 2007
  • In this research, we investigated active vibration control based on wave-viewpoint using the longitudinal wave separation method. The control strategy is the one of active vibration control technique for generating vibration reduced zone and uses wave information including the directivity as the cost function. In order to get the wave information from the measured values, we proposed and examined the time-domain longitudinal wave separation method proper to real time application like active vibration control. Using the proposed method, we examine the performance and feasibility of active vibration control based wave view-point through the simulation. The related experimental verification and application is going to be expected in a near future.

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