• Title/Summary/Keyword: Long-term damage

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Evaluation on the Basic Properties of Phosphate Modified Portland Cement Paste for Potential Application of Geologic CO2 Sequestration (이산화탄소 지중 격리용 인산염 혼입 시멘트 페이스트에 관한 기초물성 평가)

  • Yoon, Ju-Han;Kim, Seong-Geun;Kim, Ji-Hyun;Lee, Jae-Yong;Chung, Chul-Woo
    • Journal of the Korea Institute of Building Construction
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    • v.17 no.3
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    • pp.253-260
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    • 2017
  • As global warming became a worldwide issue, a significant effort has been made on the development of technology related to $CO_2$ capture and storage. Geologic sequestration of $CO_2$ is one of those technologies for safe disposal of $CO_2$. Geologic sequestration stores $CO_2$ in the form of supercritical fluid into the underground site surrounded by solid rock, and concrete is used for prevention of $CO_2$ leakage into the atmosphere. In such case, concrete may experience severe damage by attack of supercritical $CO_2$, and especially in contact with underground water, very aggressive form of carbonation can occur. In this work, to prevent such deterioration in concrete, calcium phosphates were added to the portland cement to produce hydroxyapatite, one of the most stable mineral in the world. Temperature rise, viscosity, set and stiffening, and strength development of cement paste incorporating three different types of calcium phosphates were investigated. According to the results, it was found that the addition of calcium phosphate increased apparent viscosity, but decreased maximum temperature rise and 28 day compressive strength. It was found that monocalcium phosphate was found to be inappropriate for portland cement based material. Applicability of dicalcium and tricalcium phosphates for portland cement needs to be evaluated with further investigation, including the long term compressive strength development.

Finite Element Analysis for the Contact Stress of Ultra-high Molecular Weight Polyethylene in Total Knee Arthroplasty (전 슬관절 치환 성형술에 사용되는 초고분자량 폴리에틸렌 삽입물의 접촉응력에 관한 유한요소해석)

  • Jo, Cheol-Hyeong;Choe, Jae-Bong;Choe, Gwi-Won;Yun, Gang-Seop;Gang, Seung-Baek
    • Journal of Biomedical Engineering Research
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    • v.20 no.1
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    • pp.37-44
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    • 1999
  • Because of bone resorption, wear of ultra-high molecular weight polyethylene(UHMWPE) in total knee arthroplasty has been recognized as a major factor in long-term failure of knee implant. The surface damage and the following harmful wear debris of UHMWPE is largely related to contact stress. Most of the previous studies focused on the contact condition only at the articulating surface of UHMWPE. Recently, contact stress at the metal-backing interface has been implicated as one of major factors in UHMWPE wear. Therefore, the purpose of the is study is to investigate the effect of the contact stress for different thickness, conformity friction coefficient, and flexion degree of the UHMWPE component in total knee system, considering the contact conditions at both interfaces. In this study, a two-dimensional non-linear plane strain finite element model was developed. The results showed that the maximum value of von-Mises stress occurred below the articulating surface and the contact stress was lower for the more conforming models. All-polyethylene component showed lower stress distribution than the metal-backed component. With increased friction coefficient on the tibiofemoral contact surface, the maximum shear stress increased about twofold.

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The Effects of Superior Cervical Sympathetic Ganglion Block on the Acute Phase Injury and Long Term Protection against Focal Cerebral Ischemia/Reperfusion Injury in Rats (백서의 국소 뇌허혈/재관류로 인한 신경손상에서 상경부 교감 신경절 블록의 급성기 및 장기 보호효과)

  • Jeon, Hae Young;Joung, Kyoung Woon;Choi, Jae Moon;Kim, Yoo Kyung;Shin, Jin Woo;Leem, Jeong Gill;Han, Sung Min
    • The Korean Journal of Pain
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    • v.21 no.2
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    • pp.119-125
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    • 2008
  • Background: Cerebral blood vessels are innervated by sympathetic nerves from the superior cervical ganglia (SCG), and these nerves may influence the cerebral blood flow. The purpose of the present study was to evaluate the neuroprotective effect of superior cervical sympathetic ganglion block in rats that were subjected to focal cerebral ischemia/reperfusion injury. Methods: Eighty male Sprague-Dawley rats (270-320 g) were randomly assigned to one of two groups (the ropivacaine group and a control group). In all the animals, brain injury was induced by middle cerebral artery (MCA) reperfusion that followed MCA occlusion for 2 hours. The animals of the ropivacaine group received $30{\mu}l$ of 0.75% ropivacaine, and their SCG. Neurologic score was assessed at 1, 3, 7 and 14 days after brain injury. Brain tissue samples were then collected. The infarct ratio was measured by 2.3.5-triphenyltetrazolium chloride staining. The terminal deoxynucleotidyl transferase mediated dUTP-biotin nick-end labeled (TUNEL) reactive cells and the cells showing caspase-3 activity were counted as markers of apoptosis at the caudoputamen and frontoparietal cortex. Results: The death rate, the neurologic score and the infarction ratio were significantly less in the ropivacaine group 24 hr after ischemia/reperfusion injury. The number of TUNEL positive cells in the ropivacaine group was significantly lower than those values of the control group in the frontoparietal cortex at 3 days after injury, but the caspase-3 activity was higher in the ropivacaine group than that in the control group at 1 day after injury. Conclusions: The study data indicated that a superior cervical sympathetic ganglion block may reduce the neuronal injury caused by focal cerebral ischemia/reperfusion, but it may not prevent the delayed damage.

Evaluation of Electrohydraulic Left Ventricular Assist Device through Animal Experiment (동물실험을 통한 전기유압식 좌심실 보조장치의 성능 평가)

  • Choi, J.S.;Chung, C.I.;Choi, W.W.;Park, S.K.;Jo, Y.H.;Om, K.S.;Lee, J.J.;Won, Y.S.;Kim, H.C.;Kim, W.G.;Min, B.G.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.05
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    • pp.84-87
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    • 1996
  • We have been developed electrohydraulic left ventricular assist device and done various in vivo evaluation on the device. Through the in vivo experiment conducted from Jan. 23, 1996 to Feb. 8, we could have experience of long-term evaluation fur the first time. The sheep used in this experiment had survived for 16 days. We used new actuator with reduced size and linear motion guide replacing oil box and ball bearings. Also, we used improved blood chamber with reduced size, reduced weight facilitating fixing the chamber to animal's body, and polymer sac having improved folding pattern. Against suction problem, we used absolute pressure limiter only. Motor current for driving this new actuator was not much higher than older one. Effective stroke volume was about 48 cc. Thrombosis was found around top area and peripheral boundary of the sac and valves. There was no sign of damage from suction problem in the atrium observed at autopsy. Main cause of death was presumed to be progressive formation of thrombosis in the cannulae. In this paper, the results of this experiment are documented.

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A Study on Optimization for Location and type of Dam Considering the Characteristic of Large Fault (대규모 단층특성을 고려한 최적 댐위치 및 형식 선정)

  • Kim, Han-Jung;Lyu, Young-Gwon;Kim, Young-Geun;Lim, Hee-Dae
    • Tunnel and Underground Space
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    • v.22 no.4
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    • pp.227-242
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    • 2012
  • Youngju multipurpose dam is planned to minimizing the damage by flood and obtaining the water for industrial use in Nakdong river region. Faults in rock mass have strong influences on the behaviors of dam structure. Thus, it is very important to analyse for the characteristics of fault rocks in dam design. However, due to the limitation of geotechnical investigation in design stages, engineers have to carry out the additional geological survey including directional boring to find the distribution of faults and the engineering properties of faults for stability of dam. Especially, the selection of location of dam and type of dam considering fault zone must be analyzed through various experimental and numerical analysis. In this study, various geological survey and field tests were carried out to analyse the characteristics of the large fault zone through the complex dam is designed in foundation region. Also, the distribution of structural geology, the shape of faults and the mechanical properties of fault rock were studied for the reasonable design of the location and type of dam for long-term stability of the complex dam.

Assessment of Water Circulation and Hydro-characteristics with LID techniques in urbanized areas (도시지역에 적용된 LID 기법의 강우시 수문특성 및 물순환 평가)

  • Choi, Hyeseon;Hong, Jungsun;Jeon, Minsu;Geronimo, Franz Kevin;Kim, Leehyung
    • Journal of Wetlands Research
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    • v.21 no.3
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    • pp.191-198
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    • 2019
  • High impervious surfaces increase the surface runoff during rainfall and reduces the underground infiltration thereby leading to water cycle distortion. The distortion of water cycle causes various urban environmental problems such as urban flooding, drought, water pollutant due to non-point pollution runoff, and water ecosystem damage. Climate change intensified seasonal biases in urban rainfall and affected urban microclimate, thereby increasing the intensity and frequency of urban floods and droughts. Low impact development(LID) technology has been applied to various purposes as a technique to reduce urban environmental problems caused by water by restoring the natural water cycle in the city. This study evaluated the contribution of hydrologic characteristics and water cycle recovery after LID application using long-term monitoring results of various LID technology applied in urban areas. Based on the results, the high retention and infiltration rate of the LID facility was found to contribute significantly to peak flow reduction and runoff delay during rainfall. The average runoff reduction effect was more than 60% at the LID facility. The surface area of the LID facility area ratio(SA/CA) was evaluated as an important factor affecting peak flow reduction and runoff delay effect.

Inflammatory Effect of Light-Emitting Diodes Curing Light Irradiation on Raw264.7 Macrophage

  • Jeong, Moon-Jin;Kil, Ki-Sung;Lee, Myoung-Hwa;Lee, Seung-Yeon;Lee, Hye-Jin;Lim, Do-Seon;Jeong, Soon-Jeong
    • Journal of dental hygiene science
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    • v.19 no.2
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    • pp.133-140
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    • 2019
  • Background: The light-emitting diode (LED) curing light used is presumed to be safe. However, the scientific basis for this is unclear, and the safety of LED curing light is still controversial. The purpose of this study was to investigate the effect of LED curing light irradiation according to the conditions applied for the polymerization of composite resins in dental clinic on the cell viability and inflammatory response in Raw264.7 macrophages and to confirm the stability of LED curing light. Methods: Cell viability and cell morphology of Raw264.7 macrophages treated with 100 ng/ml of lipopolysaccharide (LPS) or/and LED curing light with a wavelength of 440~490 nm for 20 seconds were confirmed by methylthiazolydiphenyl-tetrazolium bromide assay and microscopic observation. The production of nitric oxide (NO) and prostaglandin $E_2$ ($PGE_2$) was confirmed by NO assay and $PGE_2$ enzyme-linked immunosorbent assay kit. Expression of interleukin $(IL)-1{\beta}$ and tumor necrosis factor $(TNF)-{\alpha}$ in total RNA and protein was confirmed by reverse transcription polymerase chain reaction and Western blot analysis. Results: The LED curing light did not affect the viability and morphology of normal Raw264.7 cells but affected the cell viability and induced cytotoxicity in the inflammation-induced Raw264.7 cells by LPS. The irradiation of the LED curing light did not progress to the inflammatory state in the inflammation-induced Raw264.7 macrophage. However, LED curing light irradiation in normal Raw264.7 cells induced an increase in NO and $PGE_2$ production and mRNA and protein expression of $(IL)-1{\beta}$ and $(TNF)-{\alpha}$, indicating that it is possible to induce the inflammatory state. Conclusion: The irradiation of LED curing light in RAW264.7 macrophage may induce an excessive inflammatory reaction and damage oral tissues. Therefore, it is necessary to limit the long-term irradiation which is inappropriate when applying LED curing light in a dental clinic.

Evaluation of Indoor Mold Exposure Level in dwelling Using DNA-Based Mold Assessment Method (DNA 기반 곰팡이 평가기법을 활용한 주택의 실내 곰팡이 노출수준 평가)

  • Hwang, Eun-Seol;Seo, Sung Chul;Lee, Ju-Yeong;Ryu, Jung-min;Kwon, Myung-Hee;Chung, Hyen-Mi;Cho, Yong-Min;Lee, Jung-Sub
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.28 no.4
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    • pp.382-392
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    • 2018
  • Objective: Allergic diseases such as asthma due to fungal exposure in houses have increased, and proper management is urgent. Mold can grow in the air, floor, walls, and other areas according to environmental conditions, and there are many limitations to the conventional methodology for examining fungal exposure. For this reason, the degree of fungal contamination is being evaluated by ERMI (Environmental Relative Moldiness Index), a quantitative analysis method proposed by the EPA. In this study, we compared ERMI values between water-damaged dwellings and non-damaged ones to evaluate the effectiveness of Korean ERMI values. We also explored the association of ERMI values with the level of airborne mold and characteristics of dwellings. Methods: Floor dust was collected after installing a Dustream collector on the suction port of a vacuum cleaner. The collected samples were filtered to remove only 5 mg of dust, and DNA was extracted using the FastDNA SPIN KIT protocol. Results: The ERMI values were found to be 19.6 (-6.9-58.8) for flooded houses, 7.5 (-29.2-48.3) for leaks/condensation, and 0.8 (-29.2-37.9) for non-damaged dwellings. The airborne concentration of mold for flooded, leakage or condensed, and non-damaged houses were $684CFU/m^3$, $566CFU/m^3$, and $378CFU/m^3$, respectively. The correlation between ERMI values and the levels of airborne mold was low (R = 0.038), but a weakly significant association of the ERMI values with the concentration of particulate matter ($PM_{10}$) was observed as well(R=0.231,P<0.05). Conclusions: Our findings show that the reference value using ERMI can be used to distinguish water-damaged and non-damaged dwellings. It is believed that ERMI values could be a promising tool for assessing long-term fungal exposure in dwellings.

The Future of Countermobility Capability with a Literature Analysis from FASCAM to Terrain Shaping Obstacle(TSO) (미래 대기동 작전 능력의 발전방안 연구 -살포식지뢰(FASCAM)로부터 지형 조성 장애물(TSO) 전력을 중심으로-)

  • Park, Byoung-Ho;Sim, Jaeseong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.6
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    • pp.291-298
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    • 2021
  • In this study, the future of countermobility capability is presented by analyzing the status of the countermobility obstacles focusing on the history of landmines and munitions. The conventional landmine was forbidden globally by the CCW and Ottawa Treaty because it caused civilian damage after the war. Because the inhumanity of those mines had been acknowledged, shatterable mines with a self-destruct (SD) function and M93 "HORNET" anti-tank munition with enhanced sensors have been fielded. In 2016, the Obama administration announced a policy that banned all antipersonnel landmines, leaving a considerable gap in the countermobility capability. To deal with these problems, the developments of "SAVO" and the SLEP program of Volcano mines were conducted. In the sense of a long-term approach, the countermobility obstacles, including mines, were chosen as fundamental forces for Multi-Domain Operations and were improved to Terrain Shaping Obstacles (TSO). TSO has improved sensors and mobility kill capabilities and features an enhanced remote control over each munition on the battlefield through a network established with satellite communication. The combined arms countermobility might be fully capable until 2050 if the TSO program can be completed successfully.

A Change of Vegetation at the Ecological Restoration Area of Simwon Valley in Jirisan National Park (지리산국립공원 심원계곡 생태경관 복원공사지역 식생 변화)

  • Jung, Tae-Jun;Kim, Yeon-Gyeong;Kim, Young-Jin;Jung, Myung-Hee;Park, Kyoung-Hee;Shin, Chang-Keun;Park, Seung-hong;Kim, Young-Sun
    • Korean Journal of Environment and Ecology
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    • v.35 no.3
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    • pp.294-304
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    • 2021
  • This study aims to obtain basic data for systematic restoration by analyzing the monitoring results of the Shimwon Valley Ecological Landscape Restoration Project area in Jirisan National Park. In 2017, when the restoration project was completed, 12 monitoring plots and 4 control plots were installed for vegetation monitoring, and changes in the relative dominance, species diversity index and similarity between 2017 and 2020 were analyzed. The species diversity index of the surveyed areas where trees were planted during the restoration project was 0-1.4552, and the similarity index with the control group was 0% except for one survey area at 1.32%. The very low species diversity index and similarity index in the survey areas were attributed to the loss of trees planted during the restoration project due to death, damage by wild boars, or erosion by running water. On the other hand, the species diversity index was 0.9538-2.3222 in the monitoring plot where no tree was planted, and the similarity index was analyzed to be as high as 8.33%. It is necessary to continue the long-term monitoring for the development of ecological landscape restoration methods in the national park and analysis of the succession in monitoring plots where no trees were planted.