• 대한의생명과학회지
• /
• 제4권2호
• /
• pp.87-101
• /
• 1998

장기간 체중부하운동이 흰쥐의 심근에 미치는 효과를 규명하기 위하여 생후 3개월, 10개월 및 20개월된 흰쥐를 5개월간 운동시킨 후 각각의 비운동군과 비교하여 심근의 조직학적ㆍ세포학적 변화를 관찰하고, 심근세포내 미세구조적 변화를 입체해석학적으로 비교 분석하였다. 운동 15개월군부터 노화색소의 양이 현저히 증가되었고 사립체의 변성, 공포화 현상 그리고 간질조직의 증식이 뚜렷하였으며, 25개월군에서는 윤반분리, 근원섬유의 소실 및 과수축대 출현빈도가 증가되었다. Glucose-6-phosphatase의 활성도는 15개월 운동군에서 감소하여 25개월 운동군에서는 활성도가 거의 나타나지 않았다. 입체해석학적 결과에서도 장기간 체중부하운동으로 인해 15개월, 25개월군에서 모두 사립체와 근원섬유의 체적밀도는 감소되었고, 간질조직의 체적밀도는 증가되었다. 본 연구의 결과로 볼 때 장기간 체중부하운동은 3개월군에 있어서 심장에 미치는 역효과가 없으나 10개월군과 20개월군에서는 심근기능강화에 역효과를 초래 할 우려가 큰 것으로 판단된다.

• 한국항공우주학회지
• /
• 제44권9호
• /
• pp.769-774
• /
• 2016

장기간 태양광 복사환경에 노출되는 폴리머는 성능의 신뢰성을 확보하기 위해 장기간 환경시험을 필요로 한다. 본 논문에서는 MIL-STD-810을 따라 설계된 태양광 복사 시험기를 이용하여, 7, 14, 28, 56, 그리고 84 주기 동안 태양광 노화 시험을 하였다. 노화 시험 후에 RGB 값을 측정하고 CIE 1976 색공간을 이용하여, 각각의 RGB 감소율과 총 색 변화량을 계산하였다. 또한 만능재료시험기를 이용하여, ASTM-D638 시험 규격을 따라, 기계적 물성이 측정되었다. 결과적으로 태양광 노화 주기가 길어질수록, 총 색 변화량이 증가하였으며, 인장 강도, 연신율이 감소하였으나 탄성계수와 포아송 비는 변화가 적었다.

• Journal of Ginseng Research
• /
• 제46권5호
• /
• pp.657-665
• /
• 2022

Background: Sarcopenia is a new and emerging risk factor aggravating the quality of life of elderly population. Because Korean Red Ginseng (RG) is known to have a great effect on relieving fatigue and enhancing physical performance, it is invaluable to examine its potential as an anti-sarcopenic drug. Methods: Anti-sarcopenic effect of non-saponin fraction of Korean Red Ginseng (RGNS) was evaluated in C2C12 myoblasts treated with C2-ceramide to induce senescence phenotypes, and 22-month-old mice fed with chow diet containing 2% RGNS (w/w) for 4 further months. Results: The RGNS treatment significantly alleviated cellular senescence indicated by intracellular lipid accumulation, increased amount of lysosomal β-galactosidase, and reduced proliferative capacity in C2C12 myoblasts. This effect was not observed with saponin fraction. In an aged mouse, the 4-month-RGNS diet significantly improved aging-associated loss of muscle mass and strength, assessed by the weights of hindlimb skeletal muscles such as tibialis anterior (TA), extensor digitorum longus (EDL), gastrocnemius (GN) and soleus (SOL), and the cross-sectional area (CSA) of SOL muscle, and the behaviors in grip strength and hanging wire tests, respectively. During the same period, an aging-associated shift of fast-to slow-twitch muscle in SOL muscle was also retarded by the RGNS treatment. Conclusions: These findings suggested that the long-term diet of RGNS significantly prevented aging-associated muscle atrophy and reduced physical performance, and thus RGNS has a strong potential to be developed as a drug that prevents or improves sarcopenia.

• 한국콘텐츠학회논문지
• /
• 제19권1호
• /
• pp.587-597
• /
• 2019

우리나라 인구의 빠른 고령화와 일상생활이 어려운 노인들이 증가하여 사회적 연대를 위한 노인장기요양 제도가 실시되었다. 제도 도입 후 나타난 장기요양제도의 구조적 문제 해결을 요구하고 있으며 기관 및 급여유형별로 통합된 요양서비스 제공체계, 노인의료-요양의 연속성 부족에 따른 요양병원-시설 간 기능정립 문제 등도 제기되고 있다. 이 연구에서는 문제점을 개선하기 위하여 입소정원, 종사인력, 제공서비스와 관련한 연구문제를 설정하였으며 FGI를 실시하였다. 연구결과 지역 내 노인 인구와 인정자 수, 노인성 질환자수 등 장기요양 수요를 반영, 지역별 적정 기관 및 인력 수급 정책 방향 제시하고, 지자체별 목표와 수급계획을 수립하여, 장기요양기관 지정요건 절차 강화 및 지정 갱신제 등 인증제도 도입이 검토되어야 하며, 남성요양보호사 육성 및 수가 인상 등을 통한 종사자 처우개선을 통하여 원활한 인력수급이 필요하다고 보았다. 급식비의 보험적용과 유관기관과의 연계를 통한 프로그램 확대제공, 원활한 입소관리를 위한 의료외 사고 중재기구가 필요하다고 나타났다.

• 한국전기전자재료학회:학술대회논문집
• /
• 한국전기전자재료학회 2001년도 하계학술대회 논문집
• /
• pp.88-91
• /
• 2001

Our knowledge about their long-term performance in an outdoor environment is still very limited. The electrical stress caused the surface of these insulators to become degradation. In order to evaluate leakage current patterns caused by surface aging on polymeric insulators, we utilized the combined aging test facility and leakage current monitoring system. And we get the continuous leakage current values from each sample. After completing the 3000h combined aging cycle test, leakage current measurement were conducted for these samples and carried out harmonics analysis for its data.

• 한국콘크리트학회:학술대회논문집
• /
• 한국콘크리트학회 2000년도 봄 학술발표회 논문집
• /
• pp.805-810
• /
• 2000

The purpose of this study is to predict long-term structural safety on the Yonggwang Unit 3 prestressed concrete containment building. The aging-related degradations of its main structural materials are investigated and the effects of the property variation of time-dependent materials on the structural behavior of containment building are also assessed through the analysis on the ultimate pressure capacity. The nonlinear finite element analyses for both the design criteria condition a the present aging condition are conducted to assess the present structural capacity of the containment building As a result, it is verified that the structural capacity of the Yonggwang Unit 3 containment building under the present aging condition is judged to be still rugged. n addition, the sensitivity of the ultimate pressrue capacity of containment building according to th degradation levels of the structural materials are assessed. Finally, it is showed that the sensitivity levels are in the order of the tendon, rebar and concrete in case of individual material degradations, and the tendon-rebar, tendon-concrete and rebar-concrete in case of coupled material degradations.

• 한국시스템다이내믹스연구
• /
• 제15권3호
• /
• pp.105-141
• /
• 2014

Human Resource Planning and Management(HRPM) is to make organization efficiently and effectively. Based on Promotion and Aging Chain Model, a revised personnel management prediction simulation is established in terms of mid- and long-term organizational changes, annual budget and personnel strategy including a promotion, aging and laying off for the best personnel architecture in organization. Also, the model is possible to find a solution for increasing the organizational capacity. An empirical application to quasi-governmental organization proceeded to testing and validating the model.

• 한국전기전자재료학회:학술대회논문집
• /
• 한국전기전자재료학회 1999년도 춘계학술대회 논문집
• /
• pp.214-217
• /
• 1999

Polymeric composite insulators have been in use for outdoor insulation. However, our knowledge about their long-term performance in a outdoor environment is still very limited. Especially, these insulator are subjected to the environmental stress such as ultraviolet radiation. Hence, in this paper. the influence of UV radiation on the aging of the shed materials was evaluated. For the aging evaluation, these insulators studied by experiment methods such as contact angle measurement. oxidation induced time. SEM/EDX, FTRI-ATR, tracking test for the different insulator samples. With the increased UV exposure time, samples are shown to exhibit degradation comparable to those of new ones

• Elastomers and Composites
• /
• 제47권2호
• /
• pp.148-155
• /
• 2012

EPDM, IIR, 그리고 BIIR 복합체를 열노화시켜 가교밀도 변화를 조사하였다. 노화 시간이 증가하거나 노화온도가 올라갈수록 EPDM 복합체의 가교밀도는 증가하였으나, 고온에서 장기간 노화된 IIR과 BIIR 복합체의 가교밀도는 감소하는 경향을 보였다. EPDM 복합체의 가교밀도 변화에 대한 활성화 에너지는 BIIR 복합체보다 높았다. 실험결과는 알릴 수소의 수, 아연 복합체의 활성화, 입체 가리움 효과, 그리고 고무 사슬의 산화로 설명하였다.

• 전기학회논문지
• /
• 제65권9호
• /
• pp.1518-1523
• /
• 2016

In this study, in order to understand the degradation characteristics of oil-paper insulation for power transformers and OF cables, tan delta was measured using cable model specimens with long-term accelerated thermal and electrical aging. In addition, to find out the degradation level due to the accelerated aging, tensile strengths of aged papers were measured. As a result, tan ${\delta}$ showed the characteristics of slight decrease at the first stage and then increase with the aging time, which could be analyzed due to the evaporation of remaining moisture and the change of aging rate with time. Also, the trend of tensile strengths with aging temperature and time was appeared to be exponentially decreased and by use of these data equivalent calculated lifetimes and accelerated aging factors were derived for each aging temperatures. After then, tan ${\delta}$ was analyzed with the equivalent operating years. For all different aging temperatures, the aged data were very well fit to the equivalent operating years and it is shown that tan ${\delta}$ was increased with the decrease of tensile strength.