• The Journal of the Korea Contents Association
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• v.10 no.9
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• pp.176-189
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• 2010

This study focuses on the cultural and economic effects created by long-term TV dramas that run more than 20 years. The result of this study shows that long-lasting TV dramas have significant influence in increasing audience ratings of TV broadcasting companies. An analysis of Fuji Television's "From the Northern Country" shows that the drama's audience rating has more than doubled at the end period in comparison to that at the beginning stage. The analysis shows that long-term dramas also greatly contribute to the improvement of nation's cultural capability including contents development competence by producing media contents related professionals such as actors, actresses and dramatists. Fuji Television picked an actor and an actress for the drama and kept developing their talent and make a cultural accomplishment to produce new talents who compete with performance ability for the Japanese Entertainment Business. In addition, long lasting TV dramas appear to significantly contribute to local economy by promoting tourism industry of the areas where dramas are filmed. By introducing Hurano in Hokkaido which was the main stage of "From the Northern Country" to Japanese people for 21 years, the drama played a decisive role in building Hurano's brand power.

• Biomolecules & Therapeutics
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• v.12 no.1
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• pp.19-24
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• 2004

The vascular relaxant effect of amlodipine adipate, a new salt of amlodipine, was evaluate in isolated rat aorta, and compared with that of amlodipine besylate. Furthermore, antihypertensive effects were measured in hypertensive rat models, such as spontaneously hypertensive rats (SHR) and rena1 hypertensive rats (RHR). Amlodipine adipate concentration-dependently inhibited $Ca^{2+}$-induced contraction of rat aorta with a very slow onset of action (reached its maximum at 3.5 h;$IC_{50}$: 3.76 nM), having a pattern and a potency similar to those of amlodipine besylate ($IC_{50}$: 4.01 nM). In SHR and RHR, orally administered amlodipine adipate produced a dosedependent and long-lasting (>10-24 h) antihypertensive effect ($ED_{20}$: 2.48 and 1.57 mg/kg, respectively), with a pattern and a potency similar to those of amlodipine besylate ($ED_{20}$: 2.50 and 1.99 mg/kg in SHR and RHR, respectively). These results suggest that amlodipine adipate is a potent and long-lasting antihypertensive agent and that its antihypertensive effect is not significantly different to that of amlodipine besylate.

• Archives of Plastic Surgery
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• v.42 no.5
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• pp.580-587
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• 2015

Background Descent of the lateral aspect of the brow is one of the earliest signs of aging. The purpose of this study was to describe an open surgical technique for lateral brow lifts, with the goal of achieving reliable, predictable, and long-lasting results. Methods An incision was made behind and parallel to the temporal hairline, and then extended deeper through the temporoparietal fascia to the level of the deep temporal fascia. Dissection was continued anteriorly on the surface of the deep temporal fascia and subperiosteally beyond the temporal crest, to the level of the superolateral orbital rim. Fixation of the lateral brow and tightening of the orbicularis oculi muscle was achieved with the placement of sutures that secured the tissue directly to the galea aponeurotica on the lateral aspect of the incision. An additional fixation was made between the temporoparietal fascia and the deep temporal fascia, as well as between the temporoparietal fascia and the galea aponeurotica. The excess skin in the temporal area was excised and the incision was closed. Results A total of 519 patients were included in the study. Satisfactory lateral brow elevation was obtained in most of the patients (94.41%). The following complications were observed: total relapse (n=8), partial relapse (n=21), neurapraxia of the frontal branch of the facial nerve (n=5), and limited alopecia in the temporal incision (n=9). Conclusions We consider this approach to be a safe and effective procedure, with long-lasting results.

• YAKHAK HOEJI
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• v.47 no.2
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• pp.120-124
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• 2003

Due to its profound intestinal first-pass metabolism, oral eperisone hydrochloride produces a very low bioavailability and a very short muscle relaxant activity. To improve the efficacy and compliance of eperisone, we designed a new dosage form, the transdermal patch and evaluated the muscle relaxant effects of this patch in rats. The muscle relaxant activity was assessed by measurement of forelimb grip strength and hanging test in rats. The transdermal patch of eperisone hydrochloride showed significant muscle relaxant activity at 0.5, 1.5 and 3 cm$^2$/200 g rat (1.39, 4.17 and 8.33 mg of eperisone hydrochloride/kg, respectively) in a dose-dependent manner and the effects were lasted over 24 hours. The oral eperisone hydrochloride showed significant activity at 12.5, 25 and 50 mg/kg in a dose-dependent manner but the activity was within 1 or 2 hours after administration. These results suggest that the eperisone hydrochloride is absorbed efficiently from transdermal patch and the patch can exert potent and long-lasting muscle relaxant activity. This transdermal patch will increase the efficacy and compliance in the clinical use of eperisone hydrochloride.

• Archives of Plastic Surgery
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• v.34 no.1
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• pp.88-92
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• 2007

Purpose: Free nipple graft reduction mammaplasty is a simple and effective way to reduce huge breasts. However, this technique is frequently criticized for producing poor projection and hypopigmentation of the nipple areola complex(NAC). Methods: Sixty three patients(126 breasts) underwent the procedure from 1998 to 2005. Authors' method is similar with the modified Gradinger's technique except the keyhole pattern. After skin flap closing, the position of NAC is determined considering symmetry. The NAC is initially harvested and then resection of the breast followed, leaving a deepithelized inferior parenchymal pedicle($5{\times}5cm$). The upper point of inferior pedicle is sutured to the fascia of the pectoralis to produce the upper bulge. The nipple is replaced as a free and composite graft. Results: An average of 823grams of breast tissue per breast was removed. There was no major complications. All grafted nipples showed long lasting projection. And also, all NAC eventually regained their normal color except for 3 patients who needed medical tattoos. The overall results were good and patient satisfactory score was high. Conclusion: This useful technique greatly enhances long lasting projection and recovers nipple color.

• Journal of Power Electronics
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• v.16 no.4
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• pp.1268-1276
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• 2016

A triode for alternating current (TRIAC) dimming light emitting diode (LED) driver, which adopts a variable switched capacitor for LED dimming and LED power regulation, is proposed in this paper. The proposed LED driver is power efficient, reliable, and long lasting because of the TRIAC switch that serves as its main switch. Similar to previous TRIAC dimmers for lamps, turn-on timing of a TRIAC switch can be controlled by a volume resistor, which modulates the equivalent capacitance of the proposed variable switched capacitor. Thus, LED power regulation against source voltage variation and LED dimming control can be achieved by the proposed LED driver while meeting the global standards for power factor (PF) and total harmonic distortion (THD). The long life and high power efficiency of the proposed LED driver make it appropriate for industrial lighting applications, such as those for streets, factories, parking garages, and emergency stairs. The detailed analysis of the proposed LED driver and its design procedure are presented in this paper. A prototype of 80 W was fabricated and verified by experiments, which showed that the efficiency, PF, and THD at V_s = 220 V are 93.8%, 0.95, and 22.5%, respectively; 65 W of LED dimming control was achieved with the volume resistor, and the LED power variation was well mitigated below 3.75% for 190 V < V_s < 250 V.

• 한국정보디스플레이학회:학술대회논문집
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• 2007.08b
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• pp.1512-1514
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• 2007

Long afterglow $SrAl_2O_4:Eu^{2+}$,$Dy^{3+}$ is synthesized by a solid state reaction. The effect of flux $B_2O_3$ on the sintering dynamic process, the optimum concentrations of $Eu^{2+}$ and $Dy^{3+}$ for long lasting bright luminescence property and the effect of charge compensators like $Mg^{2+}$, $Zn^{2+}$, $Na^+$, $K^+$ on long persistence have been investigated.

• Journal of Korean Academy of Nursing
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• v.49 no.2
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• pp.203-214
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• 2019

Purpose: The purpose of this study to develop a fringed fall prevention program based on King's goal attainment theory and education. This study is applied to the personal, interpersonal, and social systems of fall high-risk patients to test its effects. Methods: This study was a nonequivalent control group pre- and post-test design. There were 52 fall high-risk patients in the experimental group and 45 in the control group. The experimental group received six sessions, with the group sessions lasting 60 minutes and the individual sessions lasting 20~30 minutes. Data were analyzed using descriptive statistics, an ${\chi}^2-test$, a paired sample t-test, and a Wilcoxon signed-ranks test utilizing IBM SPSS software. Results: For the 3-month intervention period, the fall prevention program was found to be particularly effective for patients in the experimental group (from 3.38 to 1.69 per 1000 patient days; p=.044), as opposed to the control group (from 1.94 to 1.49 per 1000 patient days; p=.300). For the 6-month follow up period, the fall prevention program was again found to be effective for patients in the experimental group (from 3.26 to 0.76 per 1000 patient days; p=.049) compared to the control group (from 1.98 to 1.01 per 1000 patient days; p=.368). Conclusion: These results indicate that the fringed fall prevention program is very effective in reducing falls, not only during the intervention period, but also after the intervention period has ended. We can therefore recommend this program for use concerning fall high-risk patients in long-term care hospitals.

• The Journal of Information Systems
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• v.22 no.1
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• pp.165-180
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• 2013

Using long-term panel data of OKCashbag, this study analyzes whether learning effect influencing in effectiveness of coalition loyalty program exists. We found that there is learning effect in the behavior of loyalty program customers, and discovered that learning effect appears more greatly in using (redeeming) behavior than accumulating behavior. The authors also found a long-lasting structural changes in the pattern of point redemption after a major marketing activities associated with the act of using points. The results of this research can contribute to suggest direction to the future researches to examine differences of learning effect according to demographic (gender, age, region, ect.) and transactional (frequency or scale in point accumulation and redemption etc.) characteristics.

• Sleep Medicine and Psychophysiology
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• v.7 no.1
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• pp.10-17
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• 2000

To investigate the neurobiological bases of learning and memory is one of the ambitious goals of modern neuroscience. The progress in this field of recent years has not only brought us closer to understanding the molecular mechanism underlying long-lasting changes in synaptic strength, but it has also provided further evidence that these mechanisms are required for memory formation. Since twenty years ago, several studies for the tests of the hypothesis that NMDA-dependent hippocampal long-term potentiation(LTP) underlies learning have been reported. Also, in the recent year, data from mutant mice showed that a potential role for NMDA-dependent LTP in hippocampal CA1 and spatial learning. Although the current evidence for the role of NMDA receptor in learning and memory is not still obvious, NMDA receptor seems to act as a critical switch for activation of a cascade of events that underlie synaptic plasticity.